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The map label for this gene is etfA-1 [H]

Identifier: 197117746

GI number: 197117746

Start: 1564215

End: 1565573

Strand: Direct

Name: etfA-1 [H]

Synonym: Gbem_1358

Alternate gene names: 197117746

Gene position: 1564215-1565573 (Clockwise)

Preceding gene: 197117745

Following gene: 197117747

Centisome position: 33.89

GC content: 64.83

Gene sequence:

>1359_bases
ATGAGTGAGGCAAAACCTAAACTGAAGAAGCCGCGCGGGAAGGTTCGGCTCCTAGAGGGCAAATGCATCGCCTGTGGCGC
GCGCTGCCAGAGCAGCTGTCCGGTAGACGGCATCCAGATGAGCGATGCGGGTGAGCCGCAAATAGAACTCTCCAAGTGCA
TCGGCTGCCTTAAGTGCGTGAAGGCCTGCCCGGGCTCCGCCCTGGAGATCTTCTACACCAAGGAAGAGCTGGAGATCCTG
GCGGCTCTCGCCGGGCAGCAGGACCTTGCCGAGGACGAGGCGGACCCGGAGGAGCTGGCGCGACGCGAGTACGTTGCCGG
TTACCAAGGCGTCTGGGTCTTCGTGGAGCAGACTGAAGGCGAAGCGGCCCGTGTCTCCTGGGAACTGATGGGGAAGGGGA
AGGAACTCGCCGCGAAGCTCGGCGTGGAGCTCTGCGCCGTGGTCATGGGGCACAAGGTGGAGCACCTCTGCCATGAGGCC
TTCACCTATGGCGCCGATAAGGCGTACCTACTGGACCAGCCCGTGCTGGAGTACTACCGCACTTACCCGTACCTCGACGC
GCTTTGCCACCTGATCGAGCGCTACAAACCGGAGATCGTCCTCATGGGCGCGACCGGCATGGGGCGCGATCTGGCAGGCG
CTGTGGCGACCCGGGTGAAGACGGGGCTCACCGCCGACTGCACCGGCCTCGATATCGACCCCAAACGGAACCTGATGCAG
ACCCGCCCTGCCTTCGGCGGCAACATCATGGCGACCATCATGTGCGACCGCTTCCGTCCCCAGATGGCGACGGTGCGCTC
CCACGTGATGCCGATGCCCGCGCAGACGGCCGGCCGCAGCGGCAAGATCGTCCATGCTTCCTTCCCCTTAAGTGAGTCCG
ACGTCTTCACCAAGGTGCTGCAGGTGATCCGCGACAGCAAGGCGGGGCACGTCGACATCGCCGGGGCTGAATTCATCGTC
TCCGGCGGGCGCGGCATGATGGCCAAGGAGAACTTTGCCATCCTGCAGGAGCTTGCCGATGAACTCGGAGGCGTGGTCGG
TGCATCCCGCAGCGCGGTAGACGCGGGTTGGATGCCGGGCGACCGGCAGGTGGGACAGACCGGTAAGACGGTGCGCCCGA
AGATCTACATAGCCTGCGGCATCTCCGGCGCCATTCAGCATCTGGTGGGGATGCAGGACTCCGATCTCATCATCGCTATT
AACCGTGACAAGGAAGCCCCCATCTTCGAGGTGGCGAGCTACGGCATCGTGGGCGACCTGTTCGAGGTCGTCCCCGCCAT
CACCGCCACGCTGCGCGAGCTGAAGGCCGCGAAGAACCCGGGCGGCCAGCCCGCCGACCGGGACGTCGAGGCGGCGTAA

Upstream 100 bases:

>100_bases
AGGGACATGCTGGCGGTGTAGTCACTAACAAACCTTGTGGACTGAATGGACGCCATGGACTTGGTGGATGTGATGGACGT
GACCGAAAGTGGGGAGAATG

Downstream 100 bases:

>100_bases
GGGGGGTAACCCGGTTGGGGCGCTGCCCTCACCCTAACCCTCTCCCAGAGGGAGAGGGGACTTTAACAGCACGACATGGC
CCGTCCATCCCTTCTCCCTC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSEAKPKLKKPRGKVRLLEGKCIACGARCQSSCPVDGIQMSDAGEPQIELSKCIGCLKCVKACPGSALEIFYTKEELEIL
AALAGQQDLAEDEADPEELARREYVAGYQGVWVFVEQTEGEAARVSWELMGKGKELAAKLGVELCAVVMGHKVEHLCHEA
FTYGADKAYLLDQPVLEYYRTYPYLDALCHLIERYKPEIVLMGATGMGRDLAGAVATRVKTGLTADCTGLDIDPKRNLMQ
TRPAFGGNIMATIMCDRFRPQMATVRSHVMPMPAQTAGRSGKIVHASFPLSESDVFTKVLQVIRDSKAGHVDIAGAEFIV
SGGRGMMAKENFAILQELADELGGVVGASRSAVDAGWMPGDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDLIIAI
NRDKEAPIFEVASYGIVGDLFEVVPAITATLRELKAAKNPGGQPADRDVEAA

Sequences:

>Translated_452_residues
MSEAKPKLKKPRGKVRLLEGKCIACGARCQSSCPVDGIQMSDAGEPQIELSKCIGCLKCVKACPGSALEIFYTKEELEIL
AALAGQQDLAEDEADPEELARREYVAGYQGVWVFVEQTEGEAARVSWELMGKGKELAAKLGVELCAVVMGHKVEHLCHEA
FTYGADKAYLLDQPVLEYYRTYPYLDALCHLIERYKPEIVLMGATGMGRDLAGAVATRVKTGLTADCTGLDIDPKRNLMQ
TRPAFGGNIMATIMCDRFRPQMATVRSHVMPMPAQTAGRSGKIVHASFPLSESDVFTKVLQVIRDSKAGHVDIAGAEFIV
SGGRGMMAKENFAILQELADELGGVVGASRSAVDAGWMPGDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDLIIAI
NRDKEAPIFEVASYGIVGDLFEVVPAITATLRELKAAKNPGGQPADRDVEAA
>Mature_451_residues
SEAKPKLKKPRGKVRLLEGKCIACGARCQSSCPVDGIQMSDAGEPQIELSKCIGCLKCVKACPGSALEIFYTKEELEILA
ALAGQQDLAEDEADPEELARREYVAGYQGVWVFVEQTEGEAARVSWELMGKGKELAAKLGVELCAVVMGHKVEHLCHEAF
TYGADKAYLLDQPVLEYYRTYPYLDALCHLIERYKPEIVLMGATGMGRDLAGAVATRVKTGLTADCTGLDIDPKRNLMQT
RPAFGGNIMATIMCDRFRPQMATVRSHVMPMPAQTAGRSGKIVHASFPLSESDVFTKVLQVIRDSKAGHVDIAGAEFIVS
GGRGMMAKENFAILQELADELGGVVGASRSAVDAGWMPGDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDLIIAIN
RDKEAPIFEVASYGIVGDLFEVVPAITATLRELKAAKNPGGQPADRDVEAA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=347, Percent_Identity=35.1585014409222, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI189181759, Length=232, Percent_Identity=43.1034482758621, Blast_Score=181, Evalue=2e-45,
Organism=Escherichia coli, GI1787990, Length=326, Percent_Identity=30.3680981595092, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786226, Length=332, Percent_Identity=29.8192771084337, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI87082157, Length=256, Percent_Identity=26.953125, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=309, Percent_Identity=36.5695792880259, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6325261, Length=204, Percent_Identity=38.7254901960784, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17136898, Length=242, Percent_Identity=43.801652892562, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24652801, Length=242, Percent_Identity=43.801652892562, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 48666; Mature: 48535

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAKPKLKKPRGKVRLLEGKCIACGARCQSSCPVDGIQMSDAGEPQIELSKCIGCLKCV
CCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHH
KACPGSALEIFYTKEELEILAALAGQQDLAEDEADPEELARREYVAGYQGVWVFVEQTEG
HHCCCCCEEEEEEHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCC
EAARVSWELMGKGKELAAKLGVELCAVVMGHKVEHLCHEAFTYGADKAYLLDQPVLEYYR
CCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHH
TYPYLDALCHLIERYKPEIVLMGATGMGRDLAGAVATRVKTGLTADCTGLDIDPKRNLMQ
HCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
TRPAFGGNIMATIMCDRFRPQMATVRSHVMPMPAQTAGRSGKIVHASFPLSESDVFTKVL
CCCCCCCCEEEEEEHHHCCHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCCHHHHHHHH
QVIRDSKAGHVDIAGAEFIVSGGRGMMAKENFAILQELADELGGVVGASRSAVDAGWMPG
HHHHCCCCCEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDLIIAINRDKEAPIFEVASYGIVGDL
CCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCHHHHH
FEVVPAITATLRELKAAKNPGGQPADRDVEAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEAKPKLKKPRGKVRLLEGKCIACGARCQSSCPVDGIQMSDAGEPQIELSKCIGCLKCV
CCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHH
KACPGSALEIFYTKEELEILAALAGQQDLAEDEADPEELARREYVAGYQGVWVFVEQTEG
HHCCCCCEEEEEEHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCC
EAARVSWELMGKGKELAAKLGVELCAVVMGHKVEHLCHEAFTYGADKAYLLDQPVLEYYR
CCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHH
TYPYLDALCHLIERYKPEIVLMGATGMGRDLAGAVATRVKTGLTADCTGLDIDPKRNLMQ
HCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
TRPAFGGNIMATIMCDRFRPQMATVRSHVMPMPAQTAGRSGKIVHASFPLSESDVFTKVL
CCCCCCCCEEEEEEHHHCCHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCCHHHHHHHH
QVIRDSKAGHVDIAGAEFIVSGGRGMMAKENFAILQELADELGGVVGASRSAVDAGWMPG
HHHHCCCCCEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDLIIAINRDKEAPIFEVASYGIVGDL
CCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCHHHHH
FEVVPAITATLRELKAAKNPGGQPADRDVEAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA