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The map label for this gene is sucC-1 [H]

Identifier: 197116660

GI number: 197116660

Start: 309159

End: 310319

Strand: Reverse

Name: sucC-1 [H]

Synonym: Gbem_0260

Alternate gene names: 197116660

Gene position: 310319-309159 (Counterclockwise)

Preceding gene: 197116661

Following gene: 197116659

Centisome position: 6.72

GC content: 63.91

Gene sequence:

>1161_bases
ATGAACATCCATGAATATCAGGCGAAGGAAATACTGAGCACATTCGGGATCCCGGTGCCCCGCGGGCGTGTGGCCCTGAC
CGCGGACCAAGTCGAGCGCGCCGCGAAGGAGATGGGCGGGCGCTGCGTGGTCAAGGCCCAGATCTACGCCGGCGGACGCG
GGAAGGCCGGCGGGGTCAAGCTGGTGCACCACCCCGAACAGGCCCAGGACCTCGCCAAGGAGCTGTTCGGAAAGACCCTG
GTGACCCCGCAGACCGGGCCGGAAGGGCTCAAGGTGAGGCGCATCCTGGTCGAGGAGGCGGTCGACATCGCCCGCGAATT
CTACCTCTCCATTACCCTGGACCGCGGCACTTCCCGCTACATCCTGATCGCCTCCGCAGAGGGGGGGATGGAGATAGAGG
AAGTGGCGACGAGGAGCCCGGAAAAGATCCACACCCTAACCATCGACCCCTTCACCGGGCTCAGGTCGTTCCAGGCGCGC
CACATCGCCCTGCAGCTGGGCCTCTCCGGGAGCGTCTGCGAGGACTGCGTCAGCCTCATCCTCAACCTCTACCGCGTCTG
CCTGGAGAAGGACTGCGCCCTGGTGGAGATCAACCCGCTGGTGGTGACCCGCGCCGGTTGGCTCATGGCCATGGATGCCA
AGATCACCTTCGACGACAACGCCATCTTCAGACACCGGGAATACCCCGACATGATGGACTACTCCCAGTTGGACCCCCTG
GAGATCAACGCAGGGAAATACGATCTCGCCTACATCAAGCTCACCGGCACCATCGGCTGCCTAGTGAACGGCGCAGGCCT
CGCCATGGCTACCCTAGACGTCCTGAAGGAATTCGGCGGCGAGCCTGCGAACTTCCTCGACGTCGGAGGGGGGGCCACCC
GCGAGAAGGTGGCCGAGGCGTTCAAGATCATCCTTCAGGACAGCGACGTGAAAGGGATCTTCGTCAACATCTTCGGCGGG
ATCATGCGCTGCGACGTGATCGCCCACGGCATCATCGAGGCCGCCAGCGAGGTGAACTGCACCCTCCCCATAGTAGTCCG
CATGGACGGGAGCCAGGTCGAGGAAGGGAAGAGGCTTCTTACCGAGAGCGGCCTCAACGTGCAATGCGGCGACAACCTTG
GGGACGCGGCCGCGCGAATCGTGAAGATGCTGGCGGGGTAG

Upstream 100 bases:

>100_bases
GGCTGCGCCACTTTTTTTCTTAGAAAAGGCTGGTAGAACAATAACGTGCGGCGCCGTCCGGTCCGCAACCGAACCACAAG
CTGCAGGACAGGAGATCATG

Downstream 100 bases:

>100_bases
CTTCGGCGACTGCGACAGGTCTTCCCTCACCCTGTCCCTCCCCCAAAGGGGGAGGGGACGCCAGGTTCCGAGGAATCCCG
TTTATGACCCATACTTAACC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKEILSTFGIPVPRGRVALTADQVERAAKEMGGRCVVKAQIYAGGRGKAGGVKLVHHPEQAQDLAKELFGKTL
VTPQTGPEGLKVRRILVEEAVDIAREFYLSITLDRGTSRYILIASAEGGMEIEEVATRSPEKIHTLTIDPFTGLRSFQAR
HIALQLGLSGSVCEDCVSLILNLYRVCLEKDCALVEINPLVVTRAGWLMAMDAKITFDDNAIFRHREYPDMMDYSQLDPL
EINAGKYDLAYIKLTGTIGCLVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEAFKIILQDSDVKGIFVNIFGG
IMRCDVIAHGIIEAASEVNCTLPIVVRMDGSQVEEGKRLLTESGLNVQCGDNLGDAAARIVKMLAG

Sequences:

>Translated_386_residues
MNIHEYQAKEILSTFGIPVPRGRVALTADQVERAAKEMGGRCVVKAQIYAGGRGKAGGVKLVHHPEQAQDLAKELFGKTL
VTPQTGPEGLKVRRILVEEAVDIAREFYLSITLDRGTSRYILIASAEGGMEIEEVATRSPEKIHTLTIDPFTGLRSFQAR
HIALQLGLSGSVCEDCVSLILNLYRVCLEKDCALVEINPLVVTRAGWLMAMDAKITFDDNAIFRHREYPDMMDYSQLDPL
EINAGKYDLAYIKLTGTIGCLVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEAFKIILQDSDVKGIFVNIFGG
IMRCDVIAHGIIEAASEVNCTLPIVVRMDGSQVEEGKRLLTESGLNVQCGDNLGDAAARIVKMLAG
>Mature_386_residues
MNIHEYQAKEILSTFGIPVPRGRVALTADQVERAAKEMGGRCVVKAQIYAGGRGKAGGVKLVHHPEQAQDLAKELFGKTL
VTPQTGPEGLKVRRILVEEAVDIAREFYLSITLDRGTSRYILIASAEGGMEIEEVATRSPEKIHTLTIDPFTGLRSFQAR
HIALQLGLSGSVCEDCVSLILNLYRVCLEKDCALVEINPLVVTRAGWLMAMDAKITFDDNAIFRHREYPDMMDYSQLDPL
EINAGKYDLAYIKLTGTIGCLVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEAFKIILQDSDVKGIFVNIFGG
IMRCDVIAHGIIEAASEVNCTLPIVVRMDGSQVEEGKRLLTESGLNVQCGDNLGDAAARIVKMLAG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=44.5012787723785, Blast_Score=338, Evalue=3e-93,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.9086161879896, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=45.4545454545455, Blast_Score=309, Evalue=2e-84,
Organism=Escherichia coli, GI1786948, Length=387, Percent_Identity=50.1291989664083, Blast_Score=381, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=47.1794871794872, Blast_Score=327, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=41.3705583756345, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=44.6700507614213, Blast_Score=346, Evalue=3e-96,
Organism=Drosophila melanogaster, GI161078106, Length=397, Percent_Identity=46.5994962216625, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI24645208, Length=397, Percent_Identity=46.5994962216625, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI281361397, Length=398, Percent_Identity=46.7336683417085, Blast_Score=340, Evalue=9e-94,
Organism=Drosophila melanogaster, GI281361395, Length=398, Percent_Identity=46.7336683417085, Blast_Score=340, Evalue=9e-94,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=41.0126582278481, Blast_Score=300, Evalue=8e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41824; Mature: 41824

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILSTFGIPVPRGRVALTADQVERAAKEMGGRCVVKAQIYAGGRGKAGGVK
CCCHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEE
LVHHPEQAQDLAKELFGKTLVTPQTGPEGLKVRRILVEEAVDIAREFYLSITLDRGTSRY
EEECCHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCEE
ILIASAEGGMEIEEVATRSPEKIHTLTIDPFTGLRSFQARHIALQLGLSGSVCEDCVSLI
EEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCHHHHCCEEEEEEECCCCHHHHHHHHHH
LNLYRVCLEKDCALVEINPLVVTRAGWLMAMDAKITFDDNAIFRHREYPDMMDYSQLDPL
HHHHHHHHHCCCCEEEECCEEEEECCEEEEEEEEEEECCCCEEECCCCCCCCCCCCCCCE
EINAGKYDLAYIKLTGTIGCLVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEA
EECCCCEEEEEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
FKIILQDSDVKGIFVNIFGGIMRCDVIAHGIIEAASEVNCTLPIVVRMDGSQVEEGKRLL
HHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHH
TESGLNVQCGDNLGDAAARIVKMLAG
HHCCCEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKEILSTFGIPVPRGRVALTADQVERAAKEMGGRCVVKAQIYAGGRGKAGGVK
CCCHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEE
LVHHPEQAQDLAKELFGKTLVTPQTGPEGLKVRRILVEEAVDIAREFYLSITLDRGTSRY
EEECCHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCEE
ILIASAEGGMEIEEVATRSPEKIHTLTIDPFTGLRSFQARHIALQLGLSGSVCEDCVSLI
EEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCHHHHCCEEEEEEECCCCHHHHHHHHHH
LNLYRVCLEKDCALVEINPLVVTRAGWLMAMDAKITFDDNAIFRHREYPDMMDYSQLDPL
HHHHHHHHHCCCCEEEECCEEEEECCEEEEEEEEEEECCCCEEECCCCCCCCCCCCCCCE
EINAGKYDLAYIKLTGTIGCLVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEA
EECCCCEEEEEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
FKIILQDSDVKGIFVNIFGGIMRCDVIAHGIIEAASEVNCTLPIVVRMDGSQVEEGKRLL
HHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHH
TESGLNVQCGDNLGDAAARIVKMLAG
HHCCCEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA