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The map label for this gene is sucD-1 [H]

Identifier: 197116659

GI number: 197116659

Start: 308151

End: 309047

Strand: Reverse

Name: sucD-1 [H]

Synonym: Gbem_0259

Alternate gene names: 197116659

Gene position: 309047-308151 (Counterclockwise)

Preceding gene: 197116660

Following gene: 197116657

Centisome position: 6.7

GC content: 63.88

Gene sequence:

>897_bases
ATGTCCATATTGATCAATAAGTCGTCGAGAATCGTGGTGCAGGGGATCACCGGCCGCAGCGGGCTCTTTCACACCCAGCA
GTGCCGCGAGTACGGCAGCAACGTGGTAGCGGGGGTCACCCCCGGCAAAGGGGGGATTCACATCGAAGGTATCCCGGTCT
TCAACACGGTGGCCGAGGCGGTGAAGTACACCAGCGCCAACGTCTCCATGATCTTCGTGCCGCCTCCCGGCGCCGCTGAC
GCCATCCTGGAAGCGGCTGCCGCCGGTCTTGAACTGGCAGTTTGCATCACCGAGGGGATTCCGGTGCGCGACATGGTGCC
GGTGAAGGCGGTCCTGCAGCAAAGCAAGCTGCGCCTGGTCGGCCCCAACTGCCCCGGCGTCATCACCCCCGGGGAATGCA
AGATCGGCATCATGCCGGGTCACATCCACAAGCCCGGCAAGATCGGCGTCGTCTCCCGCAGCGGCACCCTCACCTACGAG
GCGGTCAAGCAGCTCACCGACATGGGGCTCGGCCAGTCGACCTGCGTCGGCATCGGGGGGGATCCCATCATCGGGATGAA
CTTCGTGGACGTGCTGAAGATGTTCAACGAGGACCCCGGCACCGAGGGAGTTTTCATGATCGGCGAGATCGGGGGAGCCG
CGGAGGAAGAGGCGGCGGTCTGGATTCAGACGCACATGAAGAAGCCGGTCGCGGCGTTTATCGCAGGCGTGACCGCGCCG
CCGGGAAAGAGGATGGGGCATGCCGGCGCCATCATCACCGGCGGCAAGGGAAAAGCTGCGGACAAGATCCGCACCCTCAC
CGAATGCGGCGTAACCGTCGCGACGAGCCCCACCAAAATGGGGGAGGCGATGCAGACGGCGATGGGTTCAAAGGGAAACG
GCAAGAAGCAGAAGTGA

Upstream 100 bases:

>100_bases
GCGACAGGTCTTCCCTCACCCTGTCCCTCCCCCAAAGGGGGAGGGGACGCCAGGTTCCGAGGAATCCCGTTTATGACCCA
TACTTAACCGGAGAGTTCAT

Downstream 100 bases:

>100_bases
CGTTGGGCTGCAGTCGCGGCAAAAAAAGGGGGACAGGCTACTTTTTCAAATCAAAAAGTAGCCTGTCCCCTTTTTCTCGT
TCAGCTTCCAGTAGATGCGA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSILINKSSRIVVQGITGRSGLFHTQQCREYGSNVVAGVTPGKGGIHIEGIPVFNTVAEAVKYTSANVSMIFVPPPGAAD
AILEAAAAGLELAVCITEGIPVRDMVPVKAVLQQSKLRLVGPNCPGVITPGECKIGIMPGHIHKPGKIGVVSRSGTLTYE
AVKQLTDMGLGQSTCVGIGGDPIIGMNFVDVLKMFNEDPGTEGVFMIGEIGGAAEEEAAVWIQTHMKKPVAAFIAGVTAP
PGKRMGHAGAIITGGKGKAADKIRTLTECGVTVATSPTKMGEAMQTAMGSKGNGKKQK

Sequences:

>Translated_298_residues
MSILINKSSRIVVQGITGRSGLFHTQQCREYGSNVVAGVTPGKGGIHIEGIPVFNTVAEAVKYTSANVSMIFVPPPGAAD
AILEAAAAGLELAVCITEGIPVRDMVPVKAVLQQSKLRLVGPNCPGVITPGECKIGIMPGHIHKPGKIGVVSRSGTLTYE
AVKQLTDMGLGQSTCVGIGGDPIIGMNFVDVLKMFNEDPGTEGVFMIGEIGGAAEEEAAVWIQTHMKKPVAAFIAGVTAP
PGKRMGHAGAIITGGKGKAADKIRTLTECGVTVATSPTKMGEAMQTAMGSKGNGKKQK
>Mature_297_residues
SILINKSSRIVVQGITGRSGLFHTQQCREYGSNVVAGVTPGKGGIHIEGIPVFNTVAEAVKYTSANVSMIFVPPPGAADA
ILEAAAAGLELAVCITEGIPVRDMVPVKAVLQQSKLRLVGPNCPGVITPGECKIGIMPGHIHKPGKIGVVSRSGTLTYEA
VKQLTDMGLGQSTCVGIGGDPIIGMNFVDVLKMFNEDPGTEGVFMIGEIGGAAEEEAAVWIQTHMKKPVAAFIAGVTAPP
GKRMGHAGAIITGGKGKAADKIRTLTECGVTVATSPTKMGEAMQTAMGSKGNGKKQK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=284, Percent_Identity=61.2676056338028, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI38569423, Length=310, Percent_Identity=28.3870967741935, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI38569421, Length=310, Percent_Identity=28.3870967741935, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786949, Length=288, Percent_Identity=62.5, Blast_Score=369, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=59.2465753424658, Blast_Score=327, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=58.9041095890411, Blast_Score=321, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI17557344, Length=280, Percent_Identity=25.7142857142857, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=280, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=50.3424657534247, Blast_Score=270, Evalue=3e-73,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=59.5890410958904, Blast_Score=313, Evalue=8e-86,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=52.7397260273973, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI281363477, Length=313, Percent_Identity=26.517571884984, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363475, Length=313, Percent_Identity=26.517571884984, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363473, Length=313, Percent_Identity=26.517571884984, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30684; Mature: 30553

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKSSRIVVQGITGRSGLFHTQQCREYGSNVVAGVTPGKGGIHIEGIPVFNTVAEA
CEEEEECCCEEEEEECCCCCCCCCHHHHHHHCCCEEEEECCCCCCEEEECCCHHHHHHHH
VKYTSANVSMIFVPPPGAADAILEAAAAGLELAVCITEGIPVRDMVPVKAVLQQSKLRLV
HHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCEEEE
GPNCPGVITPGECKIGIMPGHIHKPGKIGVVSRSGTLTYEAVKQLTDMGLGQSTCVGIGG
CCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCC
DPIIGMNFVDVLKMFNEDPGTEGVFMIGEIGGAAEEEAAVWIQTHMKKPVAAFIAGVTAP
CCEECCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHEEEEHHHHCCHHHHHHHCCCCC
PGKRMGHAGAIITGGKGKAADKIRTLTECGVTVATSPTKMGEAMQTAMGSKGNGKKQK
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SILINKSSRIVVQGITGRSGLFHTQQCREYGSNVVAGVTPGKGGIHIEGIPVFNTVAEA
EEEEECCCEEEEEECCCCCCCCCHHHHHHHCCCEEEEECCCCCCEEEECCCHHHHHHHH
VKYTSANVSMIFVPPPGAADAILEAAAAGLELAVCITEGIPVRDMVPVKAVLQQSKLRLV
HHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCEEEE
GPNCPGVITPGECKIGIMPGHIHKPGKIGVVSRSGTLTYEAVKQLTDMGLGQSTCVGIGG
CCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCC
DPIIGMNFVDVLKMFNEDPGTEGVFMIGEIGGAAEEEAAVWIQTHMKKPVAAFIAGVTAP
CCEECCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHEEEEHHHHCCHHHHHHHCCCCC
PGKRMGHAGAIITGGKGKAADKIRTLTECGVTVATSPTKMGEAMQTAMGSKGNGKKQK
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]