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The map label for this gene is prmA

Identifier: 197116641

GI number: 197116641

Start: 284626

End: 285546

Strand: Reverse

Name: prmA

Synonym: Gbem_0241

Alternate gene names: 197116641

Gene position: 285546-284626 (Counterclockwise)

Preceding gene: 197116645

Following gene: 197116640

Centisome position: 6.19

GC content: 62.54

Gene sequence:

>921_bases
ATGACTACTGACTGGGCTGAGATCGCCTGTGAAGTGCCCGCCGAAATGGTCGATTCCCTGGCCGACTTCCTGGTGGAGTT
GACCGGTAACGGGGTCGGTATCGACAACCTGCACCTGGACACCTTCTCCCTCGACACCCTTGAGGATACCCCCCTGAAAA
GCGTTAAGGGCTACCTCCCGCTCGACGACTCGCTGGAAGAGATGCGCATCCGCATAGAGCAGTTCCTGGCCCAGACCGGC
CCCTCTTTCCCCGGGTACGTCTATGCCCCTCCAGTGGTGACGGTGATCAGGAACGAGGACTGGGCCAACAACTGGAAGGT
CCACTTCAAGCCGGTGCGCATCGGCCAGAGGCTGGTGATCAAGCCGACCTGGGAGGAATACCTGAAACTTGAGGGCGACC
TGGTGATCCAGATCGATCCCGGCATGGCCTTCGGGACCGGCGCCCACCCAACCACCAAGATGTGCCTGGAAGCACTGGAG
CGGATCTGCTTCGACGCTAGCGGCGGTAAGCTCCCAAGCCCCGTCCTCGACGTCGGCACCGGCTCCGGCGTCCTCAGCAT
CGCGGCCGCGCTACTGGGTGCGAAAGAGATCGTCGCGGTAGACATCGACCCCGAAGCGGTGCGTGTCACGATGGAGAACC
TTGAGTTGAACGGCGTGGCCGACCTGGTCGCCGCCTCCACCACCAGCCTGGAGCAGCTCCCGGGAGGATTCCGGGTCGTG
GTCGCCAACATCCTCGCCGAGGAACTGGTGCGTCTTGCCGACGAACTCACCGCCCGCGTGGCACCTGGAGGATGGCTCAT
ACTCTCCGGCATCCTCACCGAAAAAGAAGCCTTCGTCTGCGCGGCGTTCAATTCGCTGGAGCTGGTGGAAAACCCGAAGG
AGCTCGAGTGGTCCTGCCTCAGCTTCAGGAAACCCCTGTAG

Upstream 100 bases:

>100_bases
CGCAGTTTTATCCGATGTCAAGGTTTTCATTGCAATTTCCCTTATTTTCCTGCTAGTTTATGCCCATAATTTGTCTAAGA
AAAGGAGCTGCAAACTCATT

Downstream 100 bases:

>100_bases
ACCATGCGCAGTTTCTTTCTCGGCGACAACGCCATCTGCGGCGACAGCGTGACCATCACCGGAGAGCTTTACCGCCACAT
GGCGCGCGTGCTGCGCATTA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTTDWAEIACEVPAEMVDSLADFLVELTGNGVGIDNLHLDTFSLDTLEDTPLKSVKGYLPLDDSLEEMRIRIEQFLAQTG
PSFPGYVYAPPVVTVIRNEDWANNWKVHFKPVRIGQRLVIKPTWEEYLKLEGDLVIQIDPGMAFGTGAHPTTKMCLEALE
RICFDASGGKLPSPVLDVGTGSGVLSIAAALLGAKEIVAVDIDPEAVRVTMENLELNGVADLVAASTTSLEQLPGGFRVV
VANILAEELVRLADELTARVAPGGWLILSGILTEKEAFVCAAFNSLELVENPKELEWSCLSFRKPL

Sequences:

>Translated_306_residues
MTTDWAEIACEVPAEMVDSLADFLVELTGNGVGIDNLHLDTFSLDTLEDTPLKSVKGYLPLDDSLEEMRIRIEQFLAQTG
PSFPGYVYAPPVVTVIRNEDWANNWKVHFKPVRIGQRLVIKPTWEEYLKLEGDLVIQIDPGMAFGTGAHPTTKMCLEALE
RICFDASGGKLPSPVLDVGTGSGVLSIAAALLGAKEIVAVDIDPEAVRVTMENLELNGVADLVAASTTSLEQLPGGFRVV
VANILAEELVRLADELTARVAPGGWLILSGILTEKEAFVCAAFNSLELVENPKELEWSCLSFRKPL
>Mature_305_residues
TTDWAEIACEVPAEMVDSLADFLVELTGNGVGIDNLHLDTFSLDTLEDTPLKSVKGYLPLDDSLEEMRIRIEQFLAQTGP
SFPGYVYAPPVVTVIRNEDWANNWKVHFKPVRIGQRLVIKPTWEEYLKLEGDLVIQIDPGMAFGTGAHPTTKMCLEALER
ICFDASGGKLPSPVLDVGTGSGVLSIAAALLGAKEIVAVDIDPEAVRVTMENLELNGVADLVAASTTSLEQLPGGFRVVV
ANILAEELVRLADELTARVAPGGWLILSGILTEKEAFVCAAFNSLELVENPKELEWSCLSFRKPL

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=213, Percent_Identity=38.4976525821596, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_GEOBB (B5E9X4)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002137068.1
- ProteinModelPortal:   B5E9X4
- GeneID:   6783066
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_0241
- HOGENOM:   HBG584653
- OMA:   IMIDPAL
- ProtClustDB:   CLSK827836
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33235; Mature: 33103

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDWAEIACEVPAEMVDSLADFLVELTGNGVGIDNLHLDTFSLDTLEDTPLKSVKGYLP
CCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCC
LDDSLEEMRIRIEQFLAQTGPSFPGYVYAPPVVTVIRNEDWANNWKVHFKPVRIGQRLVI
CCCCHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCEEEEEEEECCCEEEE
KPTWEEYLKLEGDLVIQIDPGMAFGTGAHPTTKMCLEALERICFDASGGKLPSPVLDVGT
ECCHHHHHCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
GSGVLSIAAALLGAKEIVAVDIDPEAVRVTMENLELNGVADLVAASTTSLEQLPGGFRVV
CCHHHHHHHHHHCCCEEEEEECCCHHEEEEEECCCCCCHHHHHHHCCCHHHHCCCCHHHH
VANILAEELVRLADELTARVAPGGWLILSGILTEKEAFVCAAFNSLELVENPKELEWSCL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCEEEEEECCCHHHHCCCCCCCHHHH
SFRKPL
HCCCCC
>Mature Secondary Structure 
TTDWAEIACEVPAEMVDSLADFLVELTGNGVGIDNLHLDTFSLDTLEDTPLKSVKGYLP
CCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCC
LDDSLEEMRIRIEQFLAQTGPSFPGYVYAPPVVTVIRNEDWANNWKVHFKPVRIGQRLVI
CCCCHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCEEEEEEEECCCEEEE
KPTWEEYLKLEGDLVIQIDPGMAFGTGAHPTTKMCLEALERICFDASGGKLPSPVLDVGT
ECCHHHHHCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
GSGVLSIAAALLGAKEIVAVDIDPEAVRVTMENLELNGVADLVAASTTSLEQLPGGFRVV
CCHHHHHHHHHHCCCEEEEEECCCHHEEEEEECCCCCCHHHHHHHCCCHHHHCCCCHHHH
VANILAEELVRLADELTARVAPGGWLILSGILTEKEAFVCAAFNSLELVENPKELEWSCL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCEEEEEECCCHHHHCCCCCCCHHHH
SFRKPL
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA