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The map label for this gene is yycG [H]

Identifier: 197116410

GI number: 197116410

Start: 14523

End: 16058

Strand: Direct

Name: yycG [H]

Synonym: Gbem_0010

Alternate gene names: 197116410

Gene position: 14523-16058 (Clockwise)

Preceding gene: 197116409

Following gene: 308535145

Centisome position: 0.31

GC content: 64.71

Gene sequence:

>1536_bases
ATGCAAAAGGATAAGATTCTCATCGTGGACGACGAGGCGGACATCGCGCTCATCCTCAAGCTGCAACTGGAGGACGCCGG
CTACGAGACGGTCCGGGCCCGCGATGGTGTAGAGGCCCTTGAGGCGGTGGCGCAGGAGCCGTTCGACCTCATCATGCTCG
ACATAAAGATGCCCCGCATGGACGGCCTCGAGGTGCTGAGCCGCCTGAAGGGGGACGAGACCCCCGTGGTGATGATGACC
GCCCACGGCAGCGAGGACATCGCCGTGGACGCCATGAAGAAGGGGGCGCTCGACTACATTTCGAAGCCGTTTTCCACCGA
CGACATGCTGCAGAAGGTGGAGCGCGCCATCGGCATCGACCGCACCCGCAAGGAAAACGCCAGACTCTCGCAGCAGTTGG
ACGAGGAGCGGCGCAAGATGGAGGCGGTGCTGCAGGGGATGGCCGATCTCCTGGTCGCAGTCGACCTGCAGGGGCGCATC
ATCACCTGGAGCCGGCAGGCGGCCAGGCTTCTTGCCGCCGAAGGGGAGAGCCTCTTGGGGAAAACCCTCGAAGAGGTGCT
CAAGGCCGAGGTTCCGGGGGGAGAACTCCCGGCCCGGACCGTCTTGCGCACCGGGGAGCCTCGCCTCGACGTCGGATACC
TGCTGAAGATCGGCAGCCTGACGGTGCCGGTACTCTCCTCGGCGGCGCCGCTTTGGAACGCGAACGGAGAGCTTGCGGGG
AGCGTCGAGATCATCAGGGACATCTCGAAACTCAAGGAGCTGGAGCAGGAAAAAGAGGATTTCGTGAGCATGCTCTCCCA
CGACCTCAAGTCCCCCATCACCGCGGTGGTCGGCTCCATCGACCTGGTGCGGGAGGCGAAGCTCGGCCCGGTGACCCCGG
ACCAGTCCGAATACCTGAACGCCGCCATAGAGAGCTGCGAGGAAATGGTGGAGATGATCGACACCCTGCTCGGCATCCAC
AAGTTCGAGGCGGGGAAGATGAAGCTGAACTTCCGGGAGGAAGACCCGTCGCTGCTCATCAACCGGAGCGTCACCAAGTT
TCAGACGCCGGCGCAGCGCGGCGCGATCAGCCTCTTTGCGACCCTCCCCCCGTCCCTCCCCGCTATCTCGGCCGACCGCT
CCTCGTTCAGCCGCATCCTGGGAAACCTTCTTTCCAACGCGGTGAAGTTCACCCCCGAGGGGGGGGAGATAGAGGTGTCG
GCAGACCTGGTACAGGATCCGGCACCCGTGCTGGCGCACGTACCGGAGGAGTGCTATCCCGGGCAAGAGCTGCCCAGGGA
AGGGGAGTTCGTCAGGATCAGGGTGCGCGACTCCGGCGTCGGGATTCCGCAGGAATCGCTCGGCTCCATCTTCGACCGTT
TCGTGCAGGCGAGAAACCGCCGGCAGGGAAAGACCCGCGGCACCGGCCTGGGGCTTGCCTTCTGCAGGAAGGCTGTGGAC
GCGCATGGCGGTTACATCTGGGCGGAGAGCGAGCCGGGCGCAGGGAGCGTCTTCACCCTCATGTTCCCGGCGCTTCCGGA
GGAGGAGGACGAGTAG

Upstream 100 bases:

>100_bases
AAGGAGATAGTCGAGCGGCATCACGGCAGGATCTTCTACACCGCCGCCAAGGAATACGGCAATACCTTCAGCTTCACGGT
GCCGATAATAGGGGAGACAG

Downstream 100 bases:

>100_bases
CAGCTGACCGTCCTGCACGCAGTTAAAAAACCCTTTAATTAGCCCATGCAACAGGGCCGGGGAAGAGGGGAGAGATGAAA
GTTATTTTAATCACTCCTCT

Product: response receiver sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MQKDKILIVDDEADIALILKLQLEDAGYETVRARDGVEALEAVAQEPFDLIMLDIKMPRMDGLEVLSRLKGDETPVVMMT
AHGSEDIAVDAMKKGALDYISKPFSTDDMLQKVERAIGIDRTRKENARLSQQLDEERRKMEAVLQGMADLLVAVDLQGRI
ITWSRQAARLLAAEGESLLGKTLEEVLKAEVPGGELPARTVLRTGEPRLDVGYLLKIGSLTVPVLSSAAPLWNANGELAG
SVEIIRDISKLKELEQEKEDFVSMLSHDLKSPITAVVGSIDLVREAKLGPVTPDQSEYLNAAIESCEEMVEMIDTLLGIH
KFEAGKMKLNFREEDPSLLINRSVTKFQTPAQRGAISLFATLPPSLPAISADRSSFSRILGNLLSNAVKFTPEGGEIEVS
ADLVQDPAPVLAHVPEECYPGQELPREGEFVRIRVRDSGVGIPQESLGSIFDRFVQARNRRQGKTRGTGLGLAFCRKAVD
AHGGYIWAESEPGAGSVFTLMFPALPEEEDE

Sequences:

>Translated_511_residues
MQKDKILIVDDEADIALILKLQLEDAGYETVRARDGVEALEAVAQEPFDLIMLDIKMPRMDGLEVLSRLKGDETPVVMMT
AHGSEDIAVDAMKKGALDYISKPFSTDDMLQKVERAIGIDRTRKENARLSQQLDEERRKMEAVLQGMADLLVAVDLQGRI
ITWSRQAARLLAAEGESLLGKTLEEVLKAEVPGGELPARTVLRTGEPRLDVGYLLKIGSLTVPVLSSAAPLWNANGELAG
SVEIIRDISKLKELEQEKEDFVSMLSHDLKSPITAVVGSIDLVREAKLGPVTPDQSEYLNAAIESCEEMVEMIDTLLGIH
KFEAGKMKLNFREEDPSLLINRSVTKFQTPAQRGAISLFATLPPSLPAISADRSSFSRILGNLLSNAVKFTPEGGEIEVS
ADLVQDPAPVLAHVPEECYPGQELPREGEFVRIRVRDSGVGIPQESLGSIFDRFVQARNRRQGKTRGTGLGLAFCRKAVD
AHGGYIWAESEPGAGSVFTLMFPALPEEEDE
>Mature_511_residues
MQKDKILIVDDEADIALILKLQLEDAGYETVRARDGVEALEAVAQEPFDLIMLDIKMPRMDGLEVLSRLKGDETPVVMMT
AHGSEDIAVDAMKKGALDYISKPFSTDDMLQKVERAIGIDRTRKENARLSQQLDEERRKMEAVLQGMADLLVAVDLQGRI
ITWSRQAARLLAAEGESLLGKTLEEVLKAEVPGGELPARTVLRTGEPRLDVGYLLKIGSLTVPVLSSAAPLWNANGELAG
SVEIIRDISKLKELEQEKEDFVSMLSHDLKSPITAVVGSIDLVREAKLGPVTPDQSEYLNAAIESCEEMVEMIDTLLGIH
KFEAGKMKLNFREEDPSLLINRSVTKFQTPAQRGAISLFATLPPSLPAISADRSSFSRILGNLLSNAVKFTPEGGEIEVS
ADLVQDPAPVLAHVPEECYPGQELPREGEFVRIRVRDSGVGIPQESLGSIFDRFVQARNRRQGKTRGTGLGLAFCRKAVD
AHGGYIWAESEPGAGSVFTLMFPALPEEEDE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=31.3253012048193, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI48994928, Length=297, Percent_Identity=29.96632996633, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788549, Length=388, Percent_Identity=22.680412371134, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=27.4193548387097, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=31.5175097276265, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789149, Length=248, Percent_Identity=30.6451612903226, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788550, Length=132, Percent_Identity=38.6363636363636, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=42.0168067226891, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=260, Percent_Identity=26.1538461538462, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082128, Length=256, Percent_Identity=26.953125, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=28.2868525896414, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=40, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=25.0980392156863, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=271, Percent_Identity=26.5682656826568, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=28.3185840707965, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=35.9649122807018, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790300, Length=261, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082012, Length=197, Percent_Identity=27.4111675126904, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788905, Length=115, Percent_Identity=33.0434782608696, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=22.5190839694656, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=116, Percent_Identity=32.7586206896552, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=32.5, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=42.156862745098, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=112, Percent_Identity=29.4642857142857, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789402, Length=131, Percent_Identity=29.7709923664122, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI2367329, Length=115, Percent_Identity=36.5217391304348, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788394, Length=129, Percent_Identity=34.8837209302326, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55981; Mature: 55981

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKDKILIVDDEADIALILKLQLEDAGYETVRARDGVEALEAVAQEPFDLIMLDIKMPRM
CCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCC
DGLEVLSRLKGDETPVVMMTAHGSEDIAVDAMKKGALDYISKPFSTDDMLQKVERAIGID
CHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCC
RTRKENARLSQQLDEERRKMEAVLQGMADLLVAVDLQGRIITWSRQAARLLAAEGESLLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECHHHHHHHHHCCHHHHH
KTLEEVLKAEVPGGELPARTVLRTGEPRLDVGYLLKIGSLTVPVLSSAAPLWNANGELAG
HHHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHHHHEECCCHHHHHHCCCCCCCCCCCCCH
SVEIIRDISKLKELEQEKEDFVSMLSHDLKSPITAVVGSIDLVREAKLGPVTPDQSEYLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AAIESCEEMVEMIDTLLGIHKFEAGKMKLNFREEDPSLLINRSVTKFQTPAQRGAISLFA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCHHHHCCCHHHCCEEEEE
TLPPSLPAISADRSSFSRILGNLLSNAVKFTPEGGEIEVSADLVQDPAPVLAHVPEECYP
ECCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEHHHHCCCCHHHHHCCHHCCC
GQELPREGEFVRIRVRDSGVGIPQESLGSIFDRFVQARNRRQGKTRGTGLGLAFCRKAVD
CCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AHGGYIWAESEPGAGSVFTLMFPALPEEEDE
CCCCEEEECCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MQKDKILIVDDEADIALILKLQLEDAGYETVRARDGVEALEAVAQEPFDLIMLDIKMPRM
CCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCC
DGLEVLSRLKGDETPVVMMTAHGSEDIAVDAMKKGALDYISKPFSTDDMLQKVERAIGID
CHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCC
RTRKENARLSQQLDEERRKMEAVLQGMADLLVAVDLQGRIITWSRQAARLLAAEGESLLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECHHHHHHHHHCCHHHHH
KTLEEVLKAEVPGGELPARTVLRTGEPRLDVGYLLKIGSLTVPVLSSAAPLWNANGELAG
HHHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHHHHEECCCHHHHHHCCCCCCCCCCCCCH
SVEIIRDISKLKELEQEKEDFVSMLSHDLKSPITAVVGSIDLVREAKLGPVTPDQSEYLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AAIESCEEMVEMIDTLLGIHKFEAGKMKLNFREEDPSLLINRSVTKFQTPAQRGAISLFA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCHHHHCCCHHHCCEEEEE
TLPPSLPAISADRSSFSRILGNLLSNAVKFTPEGGEIEVSADLVQDPAPVLAHVPEECYP
ECCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEHHHHCCCCHHHHHCCHHCCC
GQELPREGEFVRIRVRDSGVGIPQESLGSIFDRFVQARNRRQGKTRGTGLGLAFCRKAVD
CCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AHGGYIWAESEPGAGSVFTLMFPALPEEEDE
CCCCEEEECCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]