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The map label for this gene is bcd [H]

Identifier: 197106235

GI number: 197106235

Start: 3182820

End: 3184028

Strand: Direct

Name: bcd [H]

Synonym: PHZ_c2774

Alternate gene names: 197106235

Gene position: 3182820-3184028 (Clockwise)

Preceding gene: 197106234

Following gene: 197106236

Centisome position: 79.65

GC content: 70.64

Gene sequence:

>1209_bases
ATGGCCGATTTCGGAGGAGGCGACCTGGAGGCCTTCCGGGCCGAGGTCCGGGACTGGGTGGCGGCGAATTTCCCGCCGTC
CTGCAAGGGCAAGGGGCCGGCGGTCGGGCCCGACCGCGCGAGCGAGACGGCCGACCAGAAGGCCTGGCGCCTGGCGGTCG
GCGAGAAGGGCTGGGGCGTTCCCACCTGGCCCAAGGCCTACGGCGGCGGCGGGCTGTCCCCGCAGGAAGCCCGGGTGGTG
ACCCAGGAGTTCGGCAGGGCCGGCGCCTACAACCCCATCGTCGGCATGGGGACCATGATGTTCGGCCCCACCCTGCTGGA
ATACGGGACCGAGGAACAGAAGACGCGGCACATCCCGCTGATCGCCAACGGCGAGGTCCAGTGGTGCCAGGGCTTCTCCG
AGCCGGGCGCCGGCTCGGACCTGGCGGCGCTCTCGACCCGCGCCGAGGACAAGGGCGACCACTTCCTGGTGAGCGGCCAG
AAGATCTGGACCTCGGGCGCCCAGTGGGCCGACTGGTGCTTCTGCCTGGTGCGGACCGACTTCACCAAGAAGCACGAGGG
CATCAGCTTCGTGCTGTTCGACATGACGACGCCGGGCGTCGAGGTGCGGCCGATCCAGCTCATCTCGGGCGCCAGCCCCT
TCTGCGAGACCTTCCTCACCGACGTGAAGGTGCCGAAGGAGAACCTGGTCGGCCCGCTGAACGGCGGCTGGACCATCGCC
AAGCGCCTGCTGCAGCACGAGCGCAACAGCCTGGCGGGCGGCGGCGGCAGCGCCGGCCGCTTCGCCTCGGGCCGGGCCCC
GGCGGCGCTGGCCAAGGACTACGTCGGCCTCGACGCGCAGGGCCGCATCGCCGACGGCGACCTGCGCACGCGGATCGCCC
GCAACGACATCGACCTGAAGGCCTTCCAGCTCACCGCCATGCGGGCGATGGTGGAGTCCCGGGGCAACCAGGGCCCCTCG
GCGGCGACCTCGATCATGAAGAACGCCGCCAGCCAGACGCTGCAGGAGCGCGCCGAGCTCTGCATCGAGATCCTGGGCTC
CCAGGGCCTCGGCTGGGAGGGCGAGGGCTTCTCGCAGGAGGAGCTGACGTTCGTCCGCAACTGGCTGGGCGGCAAGGCCA
CCACGATCTACGGCGGCTCGGCCGAGATCCAGAACAACATCATCTCCAAGCGCATCCTGGGCCTCCCGGACGCGACCCAG
ACGAAATGA

Upstream 100 bases:

>100_bases
CCGAGATCAACCTCAACGTCATCTCCAAGCGGGTGCTGGGCCTGCCCGACCCGAAGTAGTTCTTTTTCCAAACCTATTTC
ATAGAGCCGGAGATTTTCAG

Downstream 100 bases:

>100_bases
GACCCCAGCCCGTCATCCCGCGGTCAGCCGAAGGCTGATCCGGGGGCCCCAAGCCGAACGGGCCGCGAAGGCCGCTTGGG
TCCCCCGGATCGCCGCGCGA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MADFGGGDLEAFRAEVRDWVAANFPPSCKGKGPAVGPDRASETADQKAWRLAVGEKGWGVPTWPKAYGGGGLSPQEARVV
TQEFGRAGAYNPIVGMGTMMFGPTLLEYGTEEQKTRHIPLIANGEVQWCQGFSEPGAGSDLAALSTRAEDKGDHFLVSGQ
KIWTSGAQWADWCFCLVRTDFTKKHEGISFVLFDMTTPGVEVRPIQLISGASPFCETFLTDVKVPKENLVGPLNGGWTIA
KRLLQHERNSLAGGGGSAGRFASGRAPAALAKDYVGLDAQGRIADGDLRTRIARNDIDLKAFQLTAMRAMVESRGNQGPS
AATSIMKNAASQTLQERAELCIEILGSQGLGWEGEGFSQEELTFVRNWLGGKATTIYGGSAEIQNNIISKRILGLPDATQ
TK

Sequences:

>Translated_402_residues
MADFGGGDLEAFRAEVRDWVAANFPPSCKGKGPAVGPDRASETADQKAWRLAVGEKGWGVPTWPKAYGGGGLSPQEARVV
TQEFGRAGAYNPIVGMGTMMFGPTLLEYGTEEQKTRHIPLIANGEVQWCQGFSEPGAGSDLAALSTRAEDKGDHFLVSGQ
KIWTSGAQWADWCFCLVRTDFTKKHEGISFVLFDMTTPGVEVRPIQLISGASPFCETFLTDVKVPKENLVGPLNGGWTIA
KRLLQHERNSLAGGGGSAGRFASGRAPAALAKDYVGLDAQGRIADGDLRTRIARNDIDLKAFQLTAMRAMVESRGNQGPS
AATSIMKNAASQTLQERAELCIEILGSQGLGWEGEGFSQEELTFVRNWLGGKATTIYGGSAEIQNNIISKRILGLPDATQ
TK
>Mature_401_residues
ADFGGGDLEAFRAEVRDWVAANFPPSCKGKGPAVGPDRASETADQKAWRLAVGEKGWGVPTWPKAYGGGGLSPQEARVVT
QEFGRAGAYNPIVGMGTMMFGPTLLEYGTEEQKTRHIPLIANGEVQWCQGFSEPGAGSDLAALSTRAEDKGDHFLVSGQK
IWTSGAQWADWCFCLVRTDFTKKHEGISFVLFDMTTPGVEVRPIQLISGASPFCETFLTDVKVPKENLVGPLNGGWTIAK
RLLQHERNSLAGGGGSAGRFASGRAPAALAKDYVGLDAQGRIADGDLRTRIARNDIDLKAFQLTAMRAMVESRGNQGPSA
ATSIMKNAASQTLQERAELCIEILGSQGLGWEGEGFSQEELTFVRNWLGGKATTIYGGSAEIQNNIISKRILGLPDATQT
K

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=347, Percent_Identity=28.5302593659942, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226958412, Length=222, Percent_Identity=31.0810810810811, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226958414, Length=219, Percent_Identity=31.9634703196347, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4557233, Length=344, Percent_Identity=28.1976744186047, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4557231, Length=355, Percent_Identity=26.7605633802817, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI187960098, Length=355, Percent_Identity=26.7605633802817, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4501857, Length=337, Percent_Identity=23.7388724035608, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI21361497, Length=261, Percent_Identity=23.7547892720307, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI76496475, Length=343, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4557235, Length=343, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7656849, Length=338, Percent_Identity=25.7396449704142, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI211971008, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48976061, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4503943, Length=362, Percent_Identity=24.0331491712707, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081958, Length=401, Percent_Identity=23.9401496259352, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786223, Length=350, Percent_Identity=21.4285714285714, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=349, Percent_Identity=28.9398280802292, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=342, Percent_Identity=28.0701754385965, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=340, Percent_Identity=28.8235294117647, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=344, Percent_Identity=28.4883720930233, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=399, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=213, Percent_Identity=30.9859154929577, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=255, Percent_Identity=27.4509803921569, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=188, Percent_Identity=28.1914893617021, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=213, Percent_Identity=29.1079812206573, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=201, Percent_Identity=27.8606965174129, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=201, Percent_Identity=27.363184079602, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=208, Percent_Identity=30.2884615384615, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=208, Percent_Identity=30.2884615384615, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21356377, Length=352, Percent_Identity=30.6818181818182, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646207, Length=392, Percent_Identity=29.0816326530612, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355753, Length=367, Percent_Identity=27.2479564032698, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24666513, Length=330, Percent_Identity=26.3636363636364, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24660351, Length=308, Percent_Identity=29.2207792207792, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281363737, Length=230, Percent_Identity=26.9565217391304, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920834, Length=343, Percent_Identity=24.7813411078717, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43057; Mature: 42926

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFGGGDLEAFRAEVRDWVAANFPPSCKGKGPAVGPDRASETADQKAWRLAVGEKGWGV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCC
PTWPKAYGGGGLSPQEARVVTQEFGRAGAYNPIVGMGTMMFGPTLLEYGTEEQKTRHIPL
CCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCE
IANGEVQWCQGFSEPGAGSDLAALSTRAEDKGDHFLVSGQKIWTSGAQWADWCFCLVRTD
EECCCHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCEEECCCCCHHHHHHHHHHCC
FTKKHEGISFVLFDMTTPGVEVRPIQLISGASPFCETFLTDVKVPKENLVGPLNGGWTIA
CHHCCCCCEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHCCCCHHHCCCCCCCCHHHH
KRLLQHERNSLAGGGGSAGRFASGRAPAALAKDYVGLDAQGRIADGDLRTRIARNDIDLK
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEECCHHHHHHHCCCCCHH
AFQLTAMRAMVESRGNQGPSAATSIMKNAASQTLQERAELCIEILGSQGLGWEGEGFSQE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
ELTFVRNWLGGKATTIYGGSAEIQNNIISKRILGLPDATQTK
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ADFGGGDLEAFRAEVRDWVAANFPPSCKGKGPAVGPDRASETADQKAWRLAVGEKGWGV
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCC
PTWPKAYGGGGLSPQEARVVTQEFGRAGAYNPIVGMGTMMFGPTLLEYGTEEQKTRHIPL
CCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCE
IANGEVQWCQGFSEPGAGSDLAALSTRAEDKGDHFLVSGQKIWTSGAQWADWCFCLVRTD
EECCCHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCEEECCCCCHHHHHHHHHHCC
FTKKHEGISFVLFDMTTPGVEVRPIQLISGASPFCETFLTDVKVPKENLVGPLNGGWTIA
CHHCCCCCEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHCCCCHHHCCCCCCCCHHHH
KRLLQHERNSLAGGGGSAGRFASGRAPAALAKDYVGLDAQGRIADGDLRTRIARNDIDLK
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEECCHHHHHHHCCCCCHH
AFQLTAMRAMVESRGNQGPSAATSIMKNAASQTLQERAELCIEILGSQGLGWEGEGFSQE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
ELTFVRNWLGGKATTIYGGSAEIQNNIISKRILGLPDATQTK
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]