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The map label for this gene is bcd [H]

Identifier: 197106234

GI number: 197106234

Start: 3181576

End: 3182778

Strand: Direct

Name: bcd [H]

Synonym: PHZ_c2773

Alternate gene names: 197106234

Gene position: 3181576-3182778 (Clockwise)

Preceding gene: 197106232

Following gene: 197106235

Centisome position: 79.61

GC content: 69.58

Gene sequence:

>1203_bases
ATGGCCGATTTCGGCGGCGCCGAGCTGGACGCCTTCCGCGCGGAGGTCCGCAGCTGGCTGGAGGCGAACTATCCCCCCGA
GCTGCGCGATCCGCAGGCGAAGACCGATCCCGAGGCGATCTGGGGCGGCCGCCCGTTCGAGGGCTCGGACGATCCGCAGA
TCGTCTGGATGCGCCGGATGGCCGAGAAGGGCTGGACCGCGCCGACCTGGCCCGCGGAATACGGCGGCGGCGGCCTTTCG
CCGCAGCAGGCCCGGGTCCTGGAGCAGGAGCTGGCCGCCGGCCGCTACCGTCAGCCGCTGGCCTCGTTCGGCGTCTGGAT
GCTGGGCCCGGTGCTGCTCGAGTACGCCAACGAAGACCAGAAGCGCGAGCACCTGCCGAAGATCATCAAGGGTGAGATCC
GCTGGTGCCAGGGCTACTCCGAGCCGGGCGCCGGCTCGGACCTCGCCGGCCTGCAGACCAAGTGCGAGGACAAGGGCGAC
CACTGGCTGATCAACGGCTCGAAAATTTGGACGAGCTACGCGAACAAGGCGGACTGGTGTTTCTGTCTCGTGCGGACGGA
CACGTCCAAGAAGCATGAGGGGATCAGCTTCGTGCTGATCGACATGGCCTCGCCGGGGGTGGAGACGCGGCCGATCCCGC
TGATCAGCGGCGAGAGCCCGTTCTGCGAGACGTTCTTCACGGACGTGAAGGTCCCGAAGGAGAACCTGGTCGGGCGGGTG
AACGGCGGCTGGGAGATCGCCAAGCGCCTCCTGCAGTACGAGCGCCAGAACATCTCGGCCGGCTTCGGCGAAGGCGGCAG
CGCGGGCGGCGCCTCGGGCGACCTGGCCCAGATCGCCAAGCGGTACGGCGCCGTCGACGCCGACCTGCGCGCCCGGATCA
CCGCCAACAAGATGAACTTCCAGGCCCTGCGCCAGACCATCGCCCGCTCGGCGGCGGAATCGAAGGCCGGCGGCGGCCCC
TCGGCGGCCACCTCGATCATCAAGTACGCCGCCGCCGAGTTCGCCAAGGAGCGGTCCGAGCTGATGGTCGAGGCCATGGG
CCACCAGGGCCTGGGCTGGGAGGGCGAGGGCTACGAGCCCGCCGAGCTGCTGGCGGTCCGCGGCTGGCTGCGCACCAAGG
CCAACTCGATCGAGGGCGGCACGTCCGAGATCAACCTCAACGTCATCTCCAAGCGGGTGCTGGGCCTGCCCGACCCGAAG
TAG

Upstream 100 bases:

>100_bases
GCCGCGCCCGCGCGCTCAAACAACTGTTTCATTCCACTTGCTCCCGCGCCGCCGAGCGCTAGAGTTGGAGCCCGCAGTTT
TTTCGAAAAGGGAGAACGCC

Downstream 100 bases:

>100_bases
TTCTTTTTCCAAACCTATTTCATAGAGCCGGAGATTTTCAGATGGCCGATTTCGGAGGAGGCGACCTGGAGGCCTTCCGG
GCCGAGGTCCGGGACTGGGT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MADFGGAELDAFRAEVRSWLEANYPPELRDPQAKTDPEAIWGGRPFEGSDDPQIVWMRRMAEKGWTAPTWPAEYGGGGLS
PQQARVLEQELAAGRYRQPLASFGVWMLGPVLLEYANEDQKREHLPKIIKGEIRWCQGYSEPGAGSDLAGLQTKCEDKGD
HWLINGSKIWTSYANKADWCFCLVRTDTSKKHEGISFVLIDMASPGVETRPIPLISGESPFCETFFTDVKVPKENLVGRV
NGGWEIAKRLLQYERQNISAGFGEGGSAGGASGDLAQIAKRYGAVDADLRARITANKMNFQALRQTIARSAAESKAGGGP
SAATSIIKYAAAEFAKERSELMVEAMGHQGLGWEGEGYEPAELLAVRGWLRTKANSIEGGTSEINLNVISKRVLGLPDPK

Sequences:

>Translated_400_residues
MADFGGAELDAFRAEVRSWLEANYPPELRDPQAKTDPEAIWGGRPFEGSDDPQIVWMRRMAEKGWTAPTWPAEYGGGGLS
PQQARVLEQELAAGRYRQPLASFGVWMLGPVLLEYANEDQKREHLPKIIKGEIRWCQGYSEPGAGSDLAGLQTKCEDKGD
HWLINGSKIWTSYANKADWCFCLVRTDTSKKHEGISFVLIDMASPGVETRPIPLISGESPFCETFFTDVKVPKENLVGRV
NGGWEIAKRLLQYERQNISAGFGEGGSAGGASGDLAQIAKRYGAVDADLRARITANKMNFQALRQTIARSAAESKAGGGP
SAATSIIKYAAAEFAKERSELMVEAMGHQGLGWEGEGYEPAELLAVRGWLRTKANSIEGGTSEINLNVISKRVLGLPDPK
>Mature_399_residues
ADFGGAELDAFRAEVRSWLEANYPPELRDPQAKTDPEAIWGGRPFEGSDDPQIVWMRRMAEKGWTAPTWPAEYGGGGLSP
QQARVLEQELAAGRYRQPLASFGVWMLGPVLLEYANEDQKREHLPKIIKGEIRWCQGYSEPGAGSDLAGLQTKCEDKGDH
WLINGSKIWTSYANKADWCFCLVRTDTSKKHEGISFVLIDMASPGVETRPIPLISGESPFCETFFTDVKVPKENLVGRVN
GGWEIAKRLLQYERQNISAGFGEGGSAGGASGDLAQIAKRYGAVDADLRARITANKMNFQALRQTIARSAAESKAGGGPS
AATSIIKYAAAEFAKERSELMVEAMGHQGLGWEGEGYEPAELLAVRGWLRTKANSIEGGTSEINLNVISKRVLGLPDPK

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=344, Percent_Identity=28.1976744186047, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI4557231, Length=344, Percent_Identity=28.1976744186047, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI4501859, Length=344, Percent_Identity=27.906976744186, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226958414, Length=210, Percent_Identity=30.4761904761905, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI4557233, Length=353, Percent_Identity=28.8951841359773, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI226958412, Length=210, Percent_Identity=30.4761904761905, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI7656849, Length=359, Percent_Identity=26.1838440111421, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI76496475, Length=312, Percent_Identity=27.8846153846154, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4557235, Length=312, Percent_Identity=27.8846153846154, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4501857, Length=397, Percent_Identity=22.4181360201511, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI21361497, Length=249, Percent_Identity=26.9076305220884, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI211971008, Length=256, Percent_Identity=26.953125, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI48976061, Length=256, Percent_Identity=26.953125, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI38505218, Length=301, Percent_Identity=25.9136212624585, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786223, Length=284, Percent_Identity=22.5352112676056, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=409, Percent_Identity=22.0048899755501, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=349, Percent_Identity=29.512893982808, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17570075, Length=354, Percent_Identity=27.9661016949153, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=344, Percent_Identity=28.7790697674419, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=340, Percent_Identity=28.2352941176471, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=256, Percent_Identity=28.125, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=345, Percent_Identity=28.695652173913, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=197, Percent_Identity=31.4720812182741, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=350, Percent_Identity=24, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=350, Percent_Identity=23.1428571428571, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=357, Percent_Identity=26.0504201680672, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=207, Percent_Identity=27.536231884058, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=231, Percent_Identity=31.6017316017316, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=231, Percent_Identity=31.6017316017316, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=198, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356377, Length=351, Percent_Identity=30.1994301994302, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24666513, Length=367, Percent_Identity=26.7029972752044, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646207, Length=348, Percent_Identity=29.5977011494253, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24660351, Length=348, Percent_Identity=28.1609195402299, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21355753, Length=291, Percent_Identity=27.4914089347079, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363737, Length=253, Percent_Identity=25.6916996047431, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43693; Mature: 43561

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFGGAELDAFRAEVRSWLEANYPPELRDPQAKTDPEAIWGGRPFEGSDDPQIVWMRRM
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHH
AEKGWTAPTWPAEYGGGGLSPQQARVLEQELAAGRYRQPLASFGVWMLGPVLLEYANEDQ
HHCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHHHHHCCCHH
KREHLPKIIKGEIRWCQGYSEPGAGSDLAGLQTKCEDKGDHWLINGSKIWTSYANKADWC
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCHHHHHCCCCCEE
FCLVRTDTSKKHEGISFVLIDMASPGVETRPIPLISGESPFCETFFTDVKVPKENLVGRV
EEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHCCCCHHHCCEEC
NGGWEIAKRLLQYERQNISAGFGEGGSAGGASGDLAQIAKRYGAVDADLRARITANKMNF
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHEEEECCHHHH
QALRQTIARSAAESKAGGGPSAATSIIKYAAAEFAKERSELMVEAMGHQGLGWEGEGYEP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
AELLAVRGWLRTKANSIEGGTSEINLNVISKRVLGLPDPK
HHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADFGGAELDAFRAEVRSWLEANYPPELRDPQAKTDPEAIWGGRPFEGSDDPQIVWMRRM
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHH
AEKGWTAPTWPAEYGGGGLSPQQARVLEQELAAGRYRQPLASFGVWMLGPVLLEYANEDQ
HHCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHHHHHCCCHH
KREHLPKIIKGEIRWCQGYSEPGAGSDLAGLQTKCEDKGDHWLINGSKIWTSYANKADWC
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCHHHHHCCCCCEE
FCLVRTDTSKKHEGISFVLIDMASPGVETRPIPLISGESPFCETFFTDVKVPKENLVGRV
EEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHCCCCHHHCCEEC
NGGWEIAKRLLQYERQNISAGFGEGGSAGGASGDLAQIAKRYGAVDADLRARITANKMNF
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHEEEECCHHHH
QALRQTIARSAAESKAGGGPSAATSIIKYAAAEFAKERSELMVEAMGHQGLGWEGEGYEP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
AELLAVRGWLRTKANSIEGGTSEINLNVISKRVLGLPDPK
HHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]