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The map label for this gene is kdpE [H]

Identifier: 197106109

GI number: 197106109

Start: 3036008

End: 3036721

Strand: Direct

Name: kdpE [H]

Synonym: PHZ_c2648

Alternate gene names: 197106109

Gene position: 3036008-3036721 (Clockwise)

Preceding gene: 197106108

Following gene: 197106120

Centisome position: 75.97

GC content: 73.95

Gene sequence:

>714_bases
ATGAGTTCCGGACGGCTGCTCCTCGTCGACGACGAGCCCCAGATCGTCCGGGCCCTGCTGCCCGCCCTGCAGGCGGCGGG
CTACGCCGTGGAGGTGGCCGGGACCGGCGAGGCGGCCCTGACCTGCCTGGCGGCCGAGCCCTGCGACGCCATCATCCTCG
ACCTCGGCCTGCCCGACATGGACGGCAAGGAGGTCATCGCGCGCATCCGCGAATGGTCCGAGGCGCCGATCCTCGTGCTG
TCGGCCCGCGACCTGGAGAGCGAGAAGATCGCCGCGCTGGACGCGGGCGCGGACGACTTCGTGAACAAGCCGGTGGGCGT
GGGCGAGCTGCTGGCGCGCCTGCGGGCCAGCCTGCGCGGCCGCGAGCGGCGCTTCGCGTCCCAGGCCATGTTCCGCAGCG
GCGATCTCGCCATCGACTTCGCCCGCCGCCGCGTGACCGTCCAGGGCGAGGAGGTGCGCCTGACGCCGCGCGAATACGAC
CTGCTGCGGATCCTGGCGCGGCACGCCGGCCGGCCGGTCACCCATCGCCAGGTCATCGCCGCCGTCTGGGGCGCGGGGGC
CCAGGTGGACGCCCAGTTCGTCCGCGTCCTCGTGGCGCAGCTTCGCCAGAAGCTCGAGGCCGAACCCTCGGCCCCGCGGC
TGCTGATGACGGAACCGGGCCTCGGCTACCGCCTGGCGGCCGAGGACGATCCCGCTACGCCGGCTCGTAGTTGA

Upstream 100 bases:

>100_bases
TCGCCCGCGGGCTGATGGAGGCGATGGACGGGGCGATCGAGGCCCGCAACGATCCCGCCGCGGGCGGCCTGGTGGTCAGT
CTCAGCCTGGAGTCCGCGGC

Downstream 100 bases:

>100_bases
GGATCGGCGCCAGCCAGCGCTCGGCGGTCCGCACGTCCCAACCTTTGCGGCGGGCGTAGTCCTCGACCTGGTCGCGCTCG
ATCCGGCCCACCCCGAAGTA

Product: response regulator(with CheY-like receiver domain and winged-helix DNA-binding domain)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSSGRLLLVDDEPQIVRALLPALQAAGYAVEVAGTGEAALTCLAAEPCDAIILDLGLPDMDGKEVIARIREWSEAPILVL
SARDLESEKIAALDAGADDFVNKPVGVGELLARLRASLRGRERRFASQAMFRSGDLAIDFARRRVTVQGEEVRLTPREYD
LLRILARHAGRPVTHRQVIAAVWGAGAQVDAQFVRVLVAQLRQKLEAEPSAPRLLMTEPGLGYRLAAEDDPATPARS

Sequences:

>Translated_237_residues
MSSGRLLLVDDEPQIVRALLPALQAAGYAVEVAGTGEAALTCLAAEPCDAIILDLGLPDMDGKEVIARIREWSEAPILVL
SARDLESEKIAALDAGADDFVNKPVGVGELLARLRASLRGRERRFASQAMFRSGDLAIDFARRRVTVQGEEVRLTPREYD
LLRILARHAGRPVTHRQVIAAVWGAGAQVDAQFVRVLVAQLRQKLEAEPSAPRLLMTEPGLGYRLAAEDDPATPARS
>Mature_236_residues
SSGRLLLVDDEPQIVRALLPALQAAGYAVEVAGTGEAALTCLAAEPCDAIILDLGLPDMDGKEVIARIREWSEAPILVLS
ARDLESEKIAALDAGADDFVNKPVGVGELLARLRASLRGRERRFASQAMFRSGDLAIDFARRRVTVQGEEVRLTPREYDL
LRILARHAGRPVTHRQVIAAVWGAGAQVDAQFVRVLVAQLRQKLEAEPSAPRLLMTEPGLGYRLAAEDDPATPARS

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=46.8181818181818, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=36.8421052631579, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=33.1858407079646, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.9557522123894, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.4932735426009, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=30.3964757709251, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=33.1818181818182, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=30.0884955752212, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=30.5309734513274, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=32.15859030837, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=28.2608695652174, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=26.271186440678, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=28.1385281385281, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=27.3504273504274, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=31.4814814814815, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=101, Percent_Identity=34.6534653465347, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25663; Mature: 25532

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGRLLLVDDEPQIVRALLPALQAAGYAVEVAGTGEAALTCLAAEPCDAIILDLGLPDM
CCCCCEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHEEEEECCCCCEEEEECCCCCC
DGKEVIARIREWSEAPILVLSARDLESEKIAALDAGADDFVNKPVGVGELLARLRASLRG
CHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHH
RERRFASQAMFRSGDLAIDFARRRVTVQGEEVRLTPREYDLLRILARHAGRPVTHRQVIA
HHHHHHHHHHHCCCCEEEEEHHCEEEECCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHH
AVWGAGAQVDAQFVRVLVAQLRQKLEAEPSAPRLLMTEPGLGYRLAAEDDPATPARS
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
SSGRLLLVDDEPQIVRALLPALQAAGYAVEVAGTGEAALTCLAAEPCDAIILDLGLPDM
CCCCEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHEEEEECCCCCEEEEECCCCCC
DGKEVIARIREWSEAPILVLSARDLESEKIAALDAGADDFVNKPVGVGELLARLRASLRG
CHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHH
RERRFASQAMFRSGDLAIDFARRRVTVQGEEVRLTPREYDLLRILARHAGRPVTHRQVIA
HHHHHHHHHHHCCCCEEEEEHHCEEEECCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHH
AVWGAGAQVDAQFVRVLVAQLRQKLEAEPSAPRLLMTEPGLGYRLAAEDDPATPARS
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]