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The map label for this gene is fadE25 [H]

Identifier: 197106002

GI number: 197106002

Start: 2916556

End: 2917731

Strand: Reverse

Name: fadE25 [H]

Synonym: PHZ_c2541

Alternate gene names: 197106002

Gene position: 2917731-2916556 (Counterclockwise)

Preceding gene: 197106003

Following gene: 197106001

Centisome position: 73.01

GC content: 70.41

Gene sequence:

>1176_bases
ATGGATTTGACCCTCGGCGAAGAGTACGACGCCTTCCGGGAGGAGGTCCTGCAGTTCCTCGCCGAGGCCTGGCCGCCGCG
CCAGCCCTCGGGAGATGAGGCCGCCGATGCGAAGGCGTTCCGGCGGCTCGCGACCGAGCGCGGGCTCCTCTACCGGCGGT
TCCCGCGGGAGTACGGCGGCTCGGGCCAGGCGCCCGATCCCCTCAAGGACCGGATCGTCCGCGAGGAGTTCGCCAGGCGG
GGCGCGCCCGGCGAACTCGCCGGCATTGGCCAGAAGATGCTCGCGCCGACGCTGCTCGCCCGCGGGGAGGAGTGGCAGAA
GCGGCGCTTCATCGCCCCGACGCTCGCGGGCGATCTCGTGTGGTGCCAAGGCTACAGCGAGCCGGGCTCCGGCTCCGATC
TGGCCTCGCTCAGGACCCGGGCCGTGCTCGACGGGGACGCATGGGTGATCGCGGGCCAGAAGATCTGGACCTCCGACGCC
CGGGCCGCGGACTACATGTTCATCTTGGTGCGCACCGAGCCCGACGCGCCGAAACACGCGGGCATCTCCTACCTGCTGCT
CGACATGAAGGCGCCGGGGATCACCATCCGGCCGCTGAAGCAGATGAACGGCGAGGCGCACTTCAACGAGGTGTTCTTCG
ACGAGGTGCGGACGCCCGCCGACTGGATCGTGGGCAAGAGGGGCGAGGGCTGGTCGGTCGCCCGCACGACGCTCTCGTTC
GAGCGCGCCAGCGTCAACGCGCCGGAGGCGATGGACGATCTGCTGCGCCGCGTGAAGGACCAGGCCCGAACCGCCCGCCG
GAACGGCCGCCCGCTGATCGAGGATCCGGTGTTCCGGGACGAGCTGGCCCGCGTGGAGGGCTACGCCATGGCCCACCGCT
ATTCGGTGCTGCGGCAGATGTCGATGGACACGGTGGGGCAGGATCCCGGGCTCGCCGGGCTCTGCAACAAGCTGGTCGGC
ACGGACGTCGGCCTCAAGATCGCGCGCCTCTTCCAGGAGGCGGCGGGCGACGCGGGCCTGCTGATGCCGGGCCCCGGCGT
AACCCGGGACGACATGGATGCGATGTTCTGGATCATGCGCTCGATGTCGGTGACCATCGCCGGTGGGACCTCGAACATCC
AACGCAACATCATCGCCGAGCGGGGCCTGGGCCTTCCTCGAGACCCGGGGAGCTGA

Upstream 100 bases:

>100_bases
AGGTCCTCGGCGAGGTGCTGGGCATGGATGCGGGTGAGATCGAACAACTGCGGAGCAAGGGCGCGGTCTGACCGAGCGCC
GCATCGACGGAGAGCAGAGC

Downstream 100 bases:

>100_bases
GGGCATGAACTTCCACCTTTCCGACGAGCAGGCGGCGCTGCAGGACGCCGTCCGGCGCTTCGCCGCCGAGCAGGCCGAGG
CCGGCGTGCGCCGGCGCGCA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MDLTLGEEYDAFREEVLQFLAEAWPPRQPSGDEAADAKAFRRLATERGLLYRRFPREYGGSGQAPDPLKDRIVREEFARR
GAPGELAGIGQKMLAPTLLARGEEWQKRRFIAPTLAGDLVWCQGYSEPGSGSDLASLRTRAVLDGDAWVIAGQKIWTSDA
RAADYMFILVRTEPDAPKHAGISYLLLDMKAPGITIRPLKQMNGEAHFNEVFFDEVRTPADWIVGKRGEGWSVARTTLSF
ERASVNAPEAMDDLLRRVKDQARTARRNGRPLIEDPVFRDELARVEGYAMAHRYSVLRQMSMDTVGQDPGLAGLCNKLVG
TDVGLKIARLFQEAAGDAGLLMPGPGVTRDDMDAMFWIMRSMSVTIAGGTSNIQRNIIAERGLGLPRDPGS

Sequences:

>Translated_391_residues
MDLTLGEEYDAFREEVLQFLAEAWPPRQPSGDEAADAKAFRRLATERGLLYRRFPREYGGSGQAPDPLKDRIVREEFARR
GAPGELAGIGQKMLAPTLLARGEEWQKRRFIAPTLAGDLVWCQGYSEPGSGSDLASLRTRAVLDGDAWVIAGQKIWTSDA
RAADYMFILVRTEPDAPKHAGISYLLLDMKAPGITIRPLKQMNGEAHFNEVFFDEVRTPADWIVGKRGEGWSVARTTLSF
ERASVNAPEAMDDLLRRVKDQARTARRNGRPLIEDPVFRDELARVEGYAMAHRYSVLRQMSMDTVGQDPGLAGLCNKLVG
TDVGLKIARLFQEAAGDAGLLMPGPGVTRDDMDAMFWIMRSMSVTIAGGTSNIQRNIIAERGLGLPRDPGS
>Mature_391_residues
MDLTLGEEYDAFREEVLQFLAEAWPPRQPSGDEAADAKAFRRLATERGLLYRRFPREYGGSGQAPDPLKDRIVREEFARR
GAPGELAGIGQKMLAPTLLARGEEWQKRRFIAPTLAGDLVWCQGYSEPGSGSDLASLRTRAVLDGDAWVIAGQKIWTSDA
RAADYMFILVRTEPDAPKHAGISYLLLDMKAPGITIRPLKQMNGEAHFNEVFFDEVRTPADWIVGKRGEGWSVARTTLSF
ERASVNAPEAMDDLLRRVKDQARTARRNGRPLIEDPVFRDELARVEGYAMAHRYSVLRQMSMDTVGQDPGLAGLCNKLVG
TDVGLKIARLFQEAAGDAGLLMPGPGVTRDDMDAMFWIMRSMSVTIAGGTSNIQRNIIAERGLGLPRDPGS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=24.6031746031746, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI226958412, Length=245, Percent_Identity=27.7551020408163, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4557233, Length=244, Percent_Identity=31.5573770491803, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI76496475, Length=395, Percent_Identity=25.8227848101266, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4557235, Length=395, Percent_Identity=25.8227848101266, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI187960098, Length=349, Percent_Identity=25.7879656160458, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4557231, Length=349, Percent_Identity=25.7879656160458, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI226958414, Length=199, Percent_Identity=28.643216080402, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4501859, Length=248, Percent_Identity=29.4354838709677, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI21361497, Length=393, Percent_Identity=23.9185750636132, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7656849, Length=351, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI48976061, Length=255, Percent_Identity=28.6274509803922, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI211971008, Length=255, Percent_Identity=28.6274509803922, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=26.1780104712042, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786223, Length=394, Percent_Identity=23.3502538071066, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=404, Percent_Identity=27.970297029703, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=346, Percent_Identity=27.1676300578035, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17538396, Length=246, Percent_Identity=28.4552845528455, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=404, Percent_Identity=25.2475247524752, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=253, Percent_Identity=25.6916996047431, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=348, Percent_Identity=27.5862068965517, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=196, Percent_Identity=30.1020408163265, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=215, Percent_Identity=26.5116279069767, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=152, Percent_Identity=30.2631578947368, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=205, Percent_Identity=28.2926829268293, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=211, Percent_Identity=27.9620853080569, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=211, Percent_Identity=28.436018957346, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24660351, Length=230, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24646207, Length=247, Percent_Identity=28.3400809716599, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24666513, Length=205, Percent_Identity=29.2682926829268, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356377, Length=244, Percent_Identity=27.0491803278689, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281363737, Length=352, Percent_Identity=25.2840909090909, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21355753, Length=251, Percent_Identity=26.6932270916335, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43223; Mature: 43223

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTLGEEYDAFREEVLQFLAEAWPPRQPSGDEAADAKAFRRLATERGLLYRRFPREYGG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCHHHCC
SGQAPDPLKDRIVREEFARRGAPGELAGIGQKMLAPTLLARGEEWQKRRFIAPTLAGDLV
CCCCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHCCCHHHHCCEE
WCQGYSEPGSGSDLASLRTRAVLDGDAWVIAGQKIWTSDARAADYMFILVRTEPDAPKHA
EECCCCCCCCCCHHHHHHHHHEECCCEEEEECCEEECCCCCCCCEEEEEEECCCCCCCCC
GISYLLLDMKAPGITIRPLKQMNGEAHFNEVFFDEVRTPADWIVGKRGEGWSVARTTLSF
CCEEEEEECCCCCCEECHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHH
ERASVNAPEAMDDLLRRVKDQARTARRNGRPLIEDPVFRDELARVEGYAMAHRYSVLRQM
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SMDTVGQDPGLAGLCNKLVGTDVGLKIARLFQEAAGDAGLLMPGPGVTRDDMDAMFWIMR
HHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHH
SMSVTIAGGTSNIQRNIIAERGLGLPRDPGS
HCEEEEECCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDLTLGEEYDAFREEVLQFLAEAWPPRQPSGDEAADAKAFRRLATERGLLYRRFPREYGG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCHHHCC
SGQAPDPLKDRIVREEFARRGAPGELAGIGQKMLAPTLLARGEEWQKRRFIAPTLAGDLV
CCCCCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHCCCHHHHCCEE
WCQGYSEPGSGSDLASLRTRAVLDGDAWVIAGQKIWTSDARAADYMFILVRTEPDAPKHA
EECCCCCCCCCCHHHHHHHHHEECCCEEEEECCEEECCCCCCCCEEEEEEECCCCCCCCC
GISYLLLDMKAPGITIRPLKQMNGEAHFNEVFFDEVRTPADWIVGKRGEGWSVARTTLSF
CCEEEEEECCCCCCEECHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHH
ERASVNAPEAMDDLLRRVKDQARTARRNGRPLIEDPVFRDELARVEGYAMAHRYSVLRQM
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SMDTVGQDPGLAGLCNKLVGTDVGLKIARLFQEAAGDAGLLMPGPGVTRDDMDAMFWIMR
HHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHH
SMSVTIAGGTSNIQRNIIAERGLGLPRDPGS
HCEEEEECCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]