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The map label for this gene is pbp [H]

Identifier: 197105472

GI number: 197105472

Start: 2246938

End: 2248542

Strand: Reverse

Name: pbp [H]

Synonym: PHZ_c2009

Alternate gene names: 197105472

Gene position: 2248542-2246938 (Counterclockwise)

Preceding gene: 197105473

Following gene: 197105470

Centisome position: 56.27

GC content: 71.4

Gene sequence:

>1605_bases
ATGCGCCGCCTGATCGCCGCCCTGGTCCTCTTCGCGCCGACTTTGGCGTGCGCGGCCCCGCCGCCCGGCTTCGACCGGCG
CGTGGAGGAGGTGCGACGCAAGCTGGACGCCGTCGGCTTCGCCGCGGTGATCGTCGAGGACGGCAAGGTCACGCTGTCGA
ACGGGTACGGGCGCAAGCACATGCAGCGCCCCGATCCGGTGGACGCCGACACCCTGTTCCAGATCGGCTCGGTGACGAAG
CACTTCACGGCCGCCGCGCTCGCCACTCTCGTCGACGAGGGGAAGCTGAAGTGGGACGATCCGGTCATCGACCACCTGCC
GGACTTCCGGATGTACGACCCGTGGGTCACGCGGGAGATGACCGTCCGCGACCTGCTCACCCACCGCAGCGGCCTGGGCC
TGGGGCAGGGGGACCTGATGTTCGTCCCGGCCAGCACCATCAGCCGCGCCGAGGTGGTCCGCCGGATCCGCCACCTGAAG
CCGGCGACGAGCTTCCGGTCGGGATACGCCTACGACAACATCCTCTACGCCGTGGCGGGGCAGCTGGTGGAGGCCAAGAC
CGGCCGCACCTGGGAGGCCTACGTCCGCGACCGGCTGCTGAAGCCGGCGGGCATGGCCGACTCGGTCACCAACGATCCCG
ACCGCTGGACCGTGGCCAACCGGGCGCTGCCGCACGGCAGGCTGGGGGAAATCCGGGGCCTCGGCCCCCAGGAGCCCCTC
GACGAGAAGGGCGTGGCGCTGGGCCAGAACGTCGGCCCGGCCGGCGCCGTCTCCTCCAGCGCCAACGACATGGGCCGCTG
GCTGCAGGTCCAGCTCGGCGAGGGGAAGGCGGCCTCGGGCGCCCAGGTGTTCTCGGCCGCCGCGGCGCGGGAGATGTGGA
AGCCGGTGGTGCTGATCAACGCCCCGCCGTTCCCAGGCGCCCTGGCCGAGGCCAGCCCGCAGTTCAGCACCTATGCGCTG
GGTTGGAACGTGAAGGACTACCGCGGCCACAAGGTCATCAGCCACGGCGGCGGCACGCTGGGCTTCCGCGCCGTGGCGGT
GCTGATCCCCGAGAAGAACGTCGGCTTTGCGATGATGGTGAACTCCGAGGAGAACGCCATGATCCCCGCCCTCACCAACG
AGCTCCTCGACCACTACCTGGGGCTGCCGAGGCGCGACTGGGTCGCCGCCTATACCGAATTCCTGGACCGGCGGATGGCC
GAGGGCCTGAAGGCCGCCCGCGCCGCCCGCCAGGCGCGCCCGGCCGCCTCGAAGCCGTTCCTCCCGGCGGAGGGCTACGC
CGGGACCTACGCCGATCCCTGGTATGGCCCCATCGCCGTGAAGGCGCAGGACGGCGCGCTCTCCATCGATTTCCTGCAGA
CGCCCGGGATGACGGCGCCGCTGGAGCACTGGGCCTACGACACCTTCGTCGCCCGCTGGAGCGACGGGGTCACCGAGCCC
GCCTTCGTGACCTTCAGCCTGGACGCCGACGGCAAGCCGGCGCGGATCGCCATGAAGGCCGTCTCGCCGGTGGCCGACTT
CAGCTACGACTTCCACGACCTCGACTTCCGGCCGGTCCCGGCGAATCAGCCGGGACCGAGCCGCCCGGGTCAGACCGGGT
CGTAG

Upstream 100 bases:

>100_bases
CTGGCCGTCTACGTCCTGCCGCTGATGACCTGGGGCGTCTGGCGCCTCGCCACCGGCCGGACCGGGCGCGCCGTCGCCGC
CTGATGGGAAAGGTCCCCCG

Downstream 100 bases:

>100_bases
GGGAAGACCGAGGCGCTGGCGCCGAGGTCCGTGAAGCTGGCCGACATGGCCGGGAAGCCCTGGGCGATCAGCGCCTCGGG
CGTCCAGCCCTCGATCCTGG

Product: beta-lactamase

Products: NA

Alternate protein names: PBP-4 [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MRRLIAALVLFAPTLACAAPPPGFDRRVEEVRRKLDAVGFAAVIVEDGKVTLSNGYGRKHMQRPDPVDADTLFQIGSVTK
HFTAAALATLVDEGKLKWDDPVIDHLPDFRMYDPWVTREMTVRDLLTHRSGLGLGQGDLMFVPASTISRAEVVRRIRHLK
PATSFRSGYAYDNILYAVAGQLVEAKTGRTWEAYVRDRLLKPAGMADSVTNDPDRWTVANRALPHGRLGEIRGLGPQEPL
DEKGVALGQNVGPAGAVSSSANDMGRWLQVQLGEGKAASGAQVFSAAAAREMWKPVVLINAPPFPGALAEASPQFSTYAL
GWNVKDYRGHKVISHGGGTLGFRAVAVLIPEKNVGFAMMVNSEENAMIPALTNELLDHYLGLPRRDWVAAYTEFLDRRMA
EGLKAARAARQARPAASKPFLPAEGYAGTYADPWYGPIAVKAQDGALSIDFLQTPGMTAPLEHWAYDTFVARWSDGVTEP
AFVTFSLDADGKPARIAMKAVSPVADFSYDFHDLDFRPVPANQPGPSRPGQTGS

Sequences:

>Translated_534_residues
MRRLIAALVLFAPTLACAAPPPGFDRRVEEVRRKLDAVGFAAVIVEDGKVTLSNGYGRKHMQRPDPVDADTLFQIGSVTK
HFTAAALATLVDEGKLKWDDPVIDHLPDFRMYDPWVTREMTVRDLLTHRSGLGLGQGDLMFVPASTISRAEVVRRIRHLK
PATSFRSGYAYDNILYAVAGQLVEAKTGRTWEAYVRDRLLKPAGMADSVTNDPDRWTVANRALPHGRLGEIRGLGPQEPL
DEKGVALGQNVGPAGAVSSSANDMGRWLQVQLGEGKAASGAQVFSAAAAREMWKPVVLINAPPFPGALAEASPQFSTYAL
GWNVKDYRGHKVISHGGGTLGFRAVAVLIPEKNVGFAMMVNSEENAMIPALTNELLDHYLGLPRRDWVAAYTEFLDRRMA
EGLKAARAARQARPAASKPFLPAEGYAGTYADPWYGPIAVKAQDGALSIDFLQTPGMTAPLEHWAYDTFVARWSDGVTEP
AFVTFSLDADGKPARIAMKAVSPVADFSYDFHDLDFRPVPANQPGPSRPGQTGS
>Mature_534_residues
MRRLIAALVLFAPTLACAAPPPGFDRRVEEVRRKLDAVGFAAVIVEDGKVTLSNGYGRKHMQRPDPVDADTLFQIGSVTK
HFTAAALATLVDEGKLKWDDPVIDHLPDFRMYDPWVTREMTVRDLLTHRSGLGLGQGDLMFVPASTISRAEVVRRIRHLK
PATSFRSGYAYDNILYAVAGQLVEAKTGRTWEAYVRDRLLKPAGMADSVTNDPDRWTVANRALPHGRLGEIRGLGPQEPL
DEKGVALGQNVGPAGAVSSSANDMGRWLQVQLGEGKAASGAQVFSAAAAREMWKPVVLINAPPFPGALAEASPQFSTYAL
GWNVKDYRGHKVISHGGGTLGFRAVAVLIPEKNVGFAMMVNSEENAMIPALTNELLDHYLGLPRRDWVAAYTEFLDRRMA
EGLKAARAARQARPAASKPFLPAEGYAGTYADPWYGPIAVKAQDGALSIDFLQTPGMTAPLEHWAYDTFVARWSDGVTEP
AFVTFSLDADGKPARIAMKAVSPVADFSYDFHDLDFRPVPANQPGPSRPGQTGS

Specific function: Involved in cell wall biosynthesis and may also act as a sensor of external penicillins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=381, Percent_Identity=24.4094488188976, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17550934, Length=226, Percent_Identity=26.9911504424779, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 58001; Mature: 58001

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLIAALVLFAPTLACAAPPPGFDRRVEEVRRKLDAVGFAAVIVEDGKVTLSNGYGRKH
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCHHH
MQRPDPVDADTLFQIGSVTKHFTAAALATLVDEGKLKWDDPVIDHLPDFRMYDPWVTREM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHH
TVRDLLTHRSGLGLGQGDLMFVPASTISRAEVVRRIRHLKPATSFRSGYAYDNILYAVAG
HHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
QLVEAKTGRTWEAYVRDRLLKPAGMADSVTNDPDRWTVANRALPHGRLGEIRGLGPQEPL
HHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHCCCCCCCCCCCCCCCCCCCC
DEKGVALGQNVGPAGAVSSSANDMGRWLQVQLGEGKAASGAQVFSAAAAREMWKPVVLIN
CCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEE
APPFPGALAEASPQFSTYALGWNVKDYRGHKVISHGGGTLGFRAVAVLIPEKNVGFAMMV
CCCCCCHHHCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEE
NSEENAMIPALTNELLDHYLGLPRRDWVAAYTEFLDRRMAEGLKAARAARQARPAASKPF
ECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LPAEGYAGTYADPWYGPIAVKAQDGALSIDFLQTPGMTAPLEHWAYDTFVARWSDGVTEP
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCC
AFVTFSLDADGKPARIAMKAVSPVADFSYDFHDLDFRPVPANQPGPSRPGQTGS
EEEEEEECCCCCCCEEEHHHHCHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRLIAALVLFAPTLACAAPPPGFDRRVEEVRRKLDAVGFAAVIVEDGKVTLSNGYGRKH
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCHHH
MQRPDPVDADTLFQIGSVTKHFTAAALATLVDEGKLKWDDPVIDHLPDFRMYDPWVTREM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHH
TVRDLLTHRSGLGLGQGDLMFVPASTISRAEVVRRIRHLKPATSFRSGYAYDNILYAVAG
HHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
QLVEAKTGRTWEAYVRDRLLKPAGMADSVTNDPDRWTVANRALPHGRLGEIRGLGPQEPL
HHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHCCCCCCCCCCCCCCCCCCCC
DEKGVALGQNVGPAGAVSSSANDMGRWLQVQLGEGKAASGAQVFSAAAAREMWKPVVLIN
CCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEE
APPFPGALAEASPQFSTYALGWNVKDYRGHKVISHGGGTLGFRAVAVLIPEKNVGFAMMV
CCCCCCHHHCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEE
NSEENAMIPALTNELLDHYLGLPRRDWVAAYTEFLDRRMAEGLKAARAARQARPAASKPF
ECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LPAEGYAGTYADPWYGPIAVKAQDGALSIDFLQTPGMTAPLEHWAYDTFVARWSDGVTEP
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCC
AFVTFSLDADGKPARIAMKAVSPVADFSYDFHDLDFRPVPANQPGPSRPGQTGS
EEEEEEECCCCCCCEEEHHHHCHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]