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The map label for this gene is cirA [H]

Identifier: 197105442

GI number: 197105442

Start: 2210321

End: 2213179

Strand: Direct

Name: cirA [H]

Synonym: PHZ_c1979

Alternate gene names: 197105442

Gene position: 2210321-2213179 (Clockwise)

Preceding gene: 197105439

Following gene: 197105446

Centisome position: 55.31

GC content: 66.77

Gene sequence:

>2859_bases
GTGCCGCAGATCATTCCAGCGACAAGAAGCAACCGCAAGGTGATTCTTATTCAGTTATCCCCGTTTCAAACACGTATTCG
CATTGACGGCGCTCCGCGGCTGCTTCAGCTTCACCGTCAAGCGCAGGCAATAGCGCTCAAAGGCTGCGGGGAGGCAGTTC
ACATGAAATTCAAGCACGGCTTGATGGCGACCAGTGCTGCGCTGGCCGCCGCCCTTGGCGCACCTGCGTACGCGCAGGGC
AGTCCAAACGTCATCGAGGAGCTGGTGGTCACCGCCGAGCGGCGGGAGCAGAGCCTGCAGGACGTGCCGGTGGCCATCTC
GGCCTTCACGTCCGAGAACCGGGACCTGATCGGCATCACCACCGTCCAGGACATGACCAACTTCACCCCGGGGCTGCAGT
ATTCCAGCCAGCTCGACCGGGTGAGCCTGCGCGGCGTGGGCCGGACGACCAACGTGCACGCCGCCGACCCGTCCGTGTCG
GTCTATTCGGACGGCATCTACACCACCTCGACCGTCGAGGCGGGCAAGACGCCCCTGTTCCTGGACCGGACCGAGGTCCT
GCGCGGGCCGCAGGCCACGCTGTACGGGCGCAACGCCATCGCCGGGGCGATCAACCTGATCTCGAGGCGGCCGACCGAAG
AATGGTACGCCGAGGCGCGGGCCACCTACGCGAACTACAACCGCCACCTGGTCGAGGGGGCCGTCTCAGGCCCGACGATG
ATCCCGGGCGTGCTGTTCCGCCTGGTGGCCAACTGGGAGAAGCAGACCGACGGCTGGTACGACAACATCGTCCCCGGCAT
GCCCGACGAGGGCAACGTCATCGACACGAACATCGTCGAGGGCCAGCTGAAGTTCAATTTCAACGAGAACTTCGAGGGCT
GGGCCAAGCTGACGACCATCGTCTGGCGCAACGGCGGCGGGGGCCCCGGCTCGCGCGGGACGTGGACGCCGGCGCCCTAC
GCCACGTTCCAGGTGGCCAATGCGGCGACGACCAACGATCCGGGCTACGGCTGCAGCGGCCGGACCACCAACGTCGTCAA
CCGCTCGCCGCTGGGCTGCACCAATCCGCAGCTCGACGATCCGCGCAAGATCGCCTCGGCGGTGCCGTTCCAGGTGAAGC
TGGACGACACCCTGATCTTCGCCAGCGAATGGACCTGGCACGCCTCGAATTTCGACATCAAGTACACGACCGGCGGGGCG
CGCTATCACTACAACCTGAACCGGCCGCCGAACGACAACGTGGCGCCGGTCGAGCGCTTCACCCTGCCCGGCGGGCTGAC
GATCTTCCCGCAGCAGCTCTACAACTACCAGGAGCGCGAGGAGTGGTGGAGCCACGAGCTCACCCTGAGCTCCACCCATG
ACGGGCCGCTGCAGTGGCTGGCCGGCGTCTATTACTGGAACGAGCACTACGAGCAGCCGACCTCGACCTACCTGTTCGAC
CAGACCCAGATCGCCCAGCCGGTCGGCGCGAGCTGCCCCCGCTTCGGCAATGTCTGCCCCCCGAACACGCTGCTCCAGCG
CACGCACGACGAGCCGCGGTTCCACATCCAGTCCAAGGCGGTCTACGGCCAGATCGACTACAGCTTCACCGACACGCTGA
AGTTCACGGCCGGCCTCCGCTACTCGGAGGACACCAAGACCGGCTCGGAAGAGGCGCGGGTCATCTGCTTCGCGTTCTTC
GCCTGCACCCCGGGGCTCTATCCCGAGCAGCTGGGCCCGTTCACGCCGGCGGTGGACCTGACCCAGACCCTGTTCGTCCC
CCGGCCGACCCCGCCGAAGGGCATCTCGCAGGATTTCACCTTCGACCCCGCCACGGGCCGCGCCCGGCGCGAGTACGACG
GCAAGTGGGACCAGGTGACCGGCAACGTCGGCTTCCAGTGGGAGCCCGACGCCGACACCAACGCCTATCTCCGCTACTCG
AAGGGCTACAAGCCCGGCGGCTTCCGGATCGGCGTGGACACGGCGCTGACCGCCAATCCCTACACCGAGAAGGAGACGCT
GGACGACGTCGAGTTCGGCGTGAAGAAGTCGTTCGGGAATTTCCAGGCCAACGTCGCGTTCTTCCACTACTGGTACAAGA
ACGCCCAGATCCCGCTGACCATCGTCGACACCGCGGGCGGCATCGTGCAGGCCAATTCGGTCTTCTACAACGTGCCCAAG
GCGATCTCTAAGGGCGTGGAGGTGGAGACCATCTGGCAGCCGGTCGACGGCCTGCAGATCCTCGCCAACTACTCCTACCT
GGACTCGCACATCACCCGCGCCCGGGGCCCGGTCGACCCGGCAGATCCGGCGGCGCTCGATCCCGACGCCAACCCGATCG
GCTCGCTCGCCGACTGCGCGGCGCGGCAGGCGAACGCGGACACCACCGACAACTGCGCGGCCGACCTGTTCTCGCTGCTC
CAGGGCGGCGGTTTCCAGCTCGGCCAGGACCTGAAGGGCCAGAAGCTGCCCCACGCGCCCAAGCACAAGGTCGCGGTGAA
CGTGAACTACACCTGGCAGCTGCCGACGGCCTCGCTGACCGGCTCGGTGAGCTACACCTGGCGCGCGGCCCAGTACGGCA
GCATCTTCAACCGCTCGTACACGCGCTCGCCATCCTGGGATCAGGTGGACGCGCGGCTGACCTACAAGCCCGAGAACGAC
AAGTACACGGTGATCCTGTTCGTCCGGAACCTGTTCGACGACGTCGGCTACGAGGGCGGCGCCGGCGCCTCCCGGCGCGA
GGGCTACATCGGACCGGCCACCGCCTCGGCGCCCGGCACGCCGGTGACGGTGATCCCCGTCTCGCAGGGGATCTCGACCA
CCTATCCGATCACGCCGCCCCGGACCTACGGGATCGAGCTGCAGTACCGCTTCTTCTAG

Upstream 100 bases:

>100_bases
AAGAAAGAAGGCGCGCCTCAGGCGCGCCCCTAGGTTGTCTATTGGGAAGAACAAGATCCGAAACCGGCGAACCGCGGCCG
ATTTCTGACGCCCCCATACT

Downstream 100 bases:

>100_bases
GGTGACCGGAGGGGCGCTCCGCCACGCGGCGGGGCGCCCTTTCGCCCTCAGGCGGCCCGGACCAGCCCTTCCAGCCGCGC
CAGCAACGCGCGCCATCCGG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 952; Mature: 951

Protein sequence:

>952_residues
MPQIIPATRSNRKVILIQLSPFQTRIRIDGAPRLLQLHRQAQAIALKGCGEAVHMKFKHGLMATSAALAAALGAPAYAQG
SPNVIEELVVTAERREQSLQDVPVAISAFTSENRDLIGITTVQDMTNFTPGLQYSSQLDRVSLRGVGRTTNVHAADPSVS
VYSDGIYTTSTVEAGKTPLFLDRTEVLRGPQATLYGRNAIAGAINLISRRPTEEWYAEARATYANYNRHLVEGAVSGPTM
IPGVLFRLVANWEKQTDGWYDNIVPGMPDEGNVIDTNIVEGQLKFNFNENFEGWAKLTTIVWRNGGGGPGSRGTWTPAPY
ATFQVANAATTNDPGYGCSGRTTNVVNRSPLGCTNPQLDDPRKIASAVPFQVKLDDTLIFASEWTWHASNFDIKYTTGGA
RYHYNLNRPPNDNVAPVERFTLPGGLTIFPQQLYNYQEREEWWSHELTLSSTHDGPLQWLAGVYYWNEHYEQPTSTYLFD
QTQIAQPVGASCPRFGNVCPPNTLLQRTHDEPRFHIQSKAVYGQIDYSFTDTLKFTAGLRYSEDTKTGSEEARVICFAFF
ACTPGLYPEQLGPFTPAVDLTQTLFVPRPTPPKGISQDFTFDPATGRARREYDGKWDQVTGNVGFQWEPDADTNAYLRYS
KGYKPGGFRIGVDTALTANPYTEKETLDDVEFGVKKSFGNFQANVAFFHYWYKNAQIPLTIVDTAGGIVQANSVFYNVPK
AISKGVEVETIWQPVDGLQILANYSYLDSHITRARGPVDPADPAALDPDANPIGSLADCAARQANADTTDNCAADLFSLL
QGGGFQLGQDLKGQKLPHAPKHKVAVNVNYTWQLPTASLTGSVSYTWRAAQYGSIFNRSYTRSPSWDQVDARLTYKPEND
KYTVILFVRNLFDDVGYEGGAGASRREGYIGPATASAPGTPVTVIPVSQGISTTYPITPPRTYGIELQYRFF

Sequences:

>Translated_952_residues
MPQIIPATRSNRKVILIQLSPFQTRIRIDGAPRLLQLHRQAQAIALKGCGEAVHMKFKHGLMATSAALAAALGAPAYAQG
SPNVIEELVVTAERREQSLQDVPVAISAFTSENRDLIGITTVQDMTNFTPGLQYSSQLDRVSLRGVGRTTNVHAADPSVS
VYSDGIYTTSTVEAGKTPLFLDRTEVLRGPQATLYGRNAIAGAINLISRRPTEEWYAEARATYANYNRHLVEGAVSGPTM
IPGVLFRLVANWEKQTDGWYDNIVPGMPDEGNVIDTNIVEGQLKFNFNENFEGWAKLTTIVWRNGGGGPGSRGTWTPAPY
ATFQVANAATTNDPGYGCSGRTTNVVNRSPLGCTNPQLDDPRKIASAVPFQVKLDDTLIFASEWTWHASNFDIKYTTGGA
RYHYNLNRPPNDNVAPVERFTLPGGLTIFPQQLYNYQEREEWWSHELTLSSTHDGPLQWLAGVYYWNEHYEQPTSTYLFD
QTQIAQPVGASCPRFGNVCPPNTLLQRTHDEPRFHIQSKAVYGQIDYSFTDTLKFTAGLRYSEDTKTGSEEARVICFAFF
ACTPGLYPEQLGPFTPAVDLTQTLFVPRPTPPKGISQDFTFDPATGRARREYDGKWDQVTGNVGFQWEPDADTNAYLRYS
KGYKPGGFRIGVDTALTANPYTEKETLDDVEFGVKKSFGNFQANVAFFHYWYKNAQIPLTIVDTAGGIVQANSVFYNVPK
AISKGVEVETIWQPVDGLQILANYSYLDSHITRARGPVDPADPAALDPDANPIGSLADCAARQANADTTDNCAADLFSLL
QGGGFQLGQDLKGQKLPHAPKHKVAVNVNYTWQLPTASLTGSVSYTWRAAQYGSIFNRSYTRSPSWDQVDARLTYKPEND
KYTVILFVRNLFDDVGYEGGAGASRREGYIGPATASAPGTPVTVIPVSQGISTTYPITPPRTYGIELQYRFF
>Mature_951_residues
PQIIPATRSNRKVILIQLSPFQTRIRIDGAPRLLQLHRQAQAIALKGCGEAVHMKFKHGLMATSAALAAALGAPAYAQGS
PNVIEELVVTAERREQSLQDVPVAISAFTSENRDLIGITTVQDMTNFTPGLQYSSQLDRVSLRGVGRTTNVHAADPSVSV
YSDGIYTTSTVEAGKTPLFLDRTEVLRGPQATLYGRNAIAGAINLISRRPTEEWYAEARATYANYNRHLVEGAVSGPTMI
PGVLFRLVANWEKQTDGWYDNIVPGMPDEGNVIDTNIVEGQLKFNFNENFEGWAKLTTIVWRNGGGGPGSRGTWTPAPYA
TFQVANAATTNDPGYGCSGRTTNVVNRSPLGCTNPQLDDPRKIASAVPFQVKLDDTLIFASEWTWHASNFDIKYTTGGAR
YHYNLNRPPNDNVAPVERFTLPGGLTIFPQQLYNYQEREEWWSHELTLSSTHDGPLQWLAGVYYWNEHYEQPTSTYLFDQ
TQIAQPVGASCPRFGNVCPPNTLLQRTHDEPRFHIQSKAVYGQIDYSFTDTLKFTAGLRYSEDTKTGSEEARVICFAFFA
CTPGLYPEQLGPFTPAVDLTQTLFVPRPTPPKGISQDFTFDPATGRARREYDGKWDQVTGNVGFQWEPDADTNAYLRYSK
GYKPGGFRIGVDTALTANPYTEKETLDDVEFGVKKSFGNFQANVAFFHYWYKNAQIPLTIVDTAGGIVQANSVFYNVPKA
ISKGVEVETIWQPVDGLQILANYSYLDSHITRARGPVDPADPAALDPDANPIGSLADCAARQANADTTDNCAADLFSLLQ
GGGFQLGQDLKGQKLPHAPKHKVAVNVNYTWQLPTASLTGSVSYTWRAAQYGSIFNRSYTRSPSWDQVDARLTYKPENDK
YTVILFVRNLFDDVGYEGGAGASRREGYIGPATASAPGTPVTVIPVSQGISTTYPITPPRTYGIELQYRFF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=173, Percent_Identity=28.9017341040462, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 105010; Mature: 104879

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQIIPATRSNRKVILIQLSPFQTRIRIDGAPRLLQLHRQAQAIALKGCGEAVHMKFKHG
CCCCCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHEEEEECCCHHEEEHHHHC
LMATSAALAAALGAPAYAQGSPNVIEELVVTAERREQSLQDVPVAISAFTSENRDLIGIT
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEE
TVQDMTNFTPGLQYSSQLDRVSLRGVGRTTNVHAADPSVSVYSDGIYTTSTVEAGKTPLF
EHHHHHCCCCCCCCHHHCCCEEEECCCCCCEEEECCCCCEEEECCEEEEEECCCCCCCEE
LDRTEVLRGPQATLYGRNAIAGAINLISRRPTEEWYAEARATYANYNRHLVEGAVSGPTM
EEHHHHHCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCCCCHH
IPGVLFRLVANWEKQTDGWYDNIVPGMPDEGNVIDTNIVEGQLKFNFNENFEGWAKLTTI
HHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCEEECEEEEEEEEEECCCCCCHHEEEEEE
VWRNGGGGPGSRGTWTPAPYATFQVANAATTNDPGYGCSGRTTNVVNRSPLGCTNPQLDD
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PRKIASAVPFQVKLDDTLIFASEWTWHASNFDIKYTTGGARYHYNLNRPPNDNVAPVERF
HHHHHHCCCEEEEECCEEEEEECCEEECCCEEEEEECCCEEEEEECCCCCCCCCCCCEEE
TLPGGLTIFPQQLYNYQEREEWWSHELTLSSTHDGPLQWLAGVYYWNEHYEQPTSTYLFD
ECCCCCEECHHHHCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHEEHHHCCCCCCEEEEC
QTQIAQPVGASCPRFGNVCPPNTLLQRTHDEPRFHIQSKAVYGQIDYSFTDTLKFTAGLR
HHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCEEEEEEECCEECEEEEEECCE
YSEDTKTGSEEARVICFAFFACTPGLYPEQLGPFTPAVDLTQTLFVPRPTPPKGISQDFT
ECCCCCCCCCCCEEEEEEEEHHCCCCCHHHCCCCCCCCCCHHEEEECCCCCCCCCCCCCE
FDPATGRARREYDGKWDQVTGNVGFQWEPDADTNAYLRYSKGYKPGGFRIGVDTALTANP
ECCCCCCCCCCCCCCCEEEECCCCEEECCCCCCCEEEEECCCCCCCCEEEECCCEEECCC
YTEKETLDDVEFGVKKSFGNFQANVAFFHYWYKNAQIPLTIVDTAGGIVQANSVFYNVPK
CCCHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEEEECCCCEEEECCEEEECCH
AISKGVEVETIWQPVDGLQILANYSYLDSHITRARGPVDPADPAALDPDANPIGSLADCA
HHHCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
ARQANADTTDNCAADLFSLLQGGGFQLGQDLKGQKLPHAPKHKVAVNVNYTWQLPTASLT
HHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCC
GSVSYTWRAAQYGSIFNRSYTRSPSWDQVDARLTYKPENDKYTVILFVRNLFDDVGYEGG
CCEEEEEEHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEHHHHHHHCCCCC
AGASRREGYIGPATASAPGTPVTVIPVSQGISTTYPITPPRTYGIELQYRFF
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
PQIIPATRSNRKVILIQLSPFQTRIRIDGAPRLLQLHRQAQAIALKGCGEAVHMKFKHG
CCCCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHEEEEECCCHHEEEHHHHC
LMATSAALAAALGAPAYAQGSPNVIEELVVTAERREQSLQDVPVAISAFTSENRDLIGIT
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEE
TVQDMTNFTPGLQYSSQLDRVSLRGVGRTTNVHAADPSVSVYSDGIYTTSTVEAGKTPLF
EHHHHHCCCCCCCCHHHCCCEEEECCCCCCEEEECCCCCEEEECCEEEEEECCCCCCCEE
LDRTEVLRGPQATLYGRNAIAGAINLISRRPTEEWYAEARATYANYNRHLVEGAVSGPTM
EEHHHHHCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCCCCHH
IPGVLFRLVANWEKQTDGWYDNIVPGMPDEGNVIDTNIVEGQLKFNFNENFEGWAKLTTI
HHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCEEECEEEEEEEEEECCCCCCHHEEEEEE
VWRNGGGGPGSRGTWTPAPYATFQVANAATTNDPGYGCSGRTTNVVNRSPLGCTNPQLDD
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PRKIASAVPFQVKLDDTLIFASEWTWHASNFDIKYTTGGARYHYNLNRPPNDNVAPVERF
HHHHHHCCCEEEEECCEEEEEECCEEECCCEEEEEECCCEEEEEECCCCCCCCCCCCEEE
TLPGGLTIFPQQLYNYQEREEWWSHELTLSSTHDGPLQWLAGVYYWNEHYEQPTSTYLFD
ECCCCCEECHHHHCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHEEHHHCCCCCCEEEEC
QTQIAQPVGASCPRFGNVCPPNTLLQRTHDEPRFHIQSKAVYGQIDYSFTDTLKFTAGLR
HHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCEEEEEEECCEECEEEEEECCE
YSEDTKTGSEEARVICFAFFACTPGLYPEQLGPFTPAVDLTQTLFVPRPTPPKGISQDFT
ECCCCCCCCCCCEEEEEEEEHHCCCCCHHHCCCCCCCCCCHHEEEECCCCCCCCCCCCCE
FDPATGRARREYDGKWDQVTGNVGFQWEPDADTNAYLRYSKGYKPGGFRIGVDTALTANP
ECCCCCCCCCCCCCCCEEEECCCCEEECCCCCCCEEEEECCCCCCCCEEEECCCEEECCC
YTEKETLDDVEFGVKKSFGNFQANVAFFHYWYKNAQIPLTIVDTAGGIVQANSVFYNVPK
CCCHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEEEECCCCEEEECCEEEECCH
AISKGVEVETIWQPVDGLQILANYSYLDSHITRARGPVDPADPAALDPDANPIGSLADCA
HHHCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
ARQANADTTDNCAADLFSLLQGGGFQLGQDLKGQKLPHAPKHKVAVNVNYTWQLPTASLT
HHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCC
GSVSYTWRAAQYGSIFNRSYTRSPSWDQVDARLTYKPENDKYTVILFVRNLFDDVGYEGG
CCEEEEEEHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEHHHHHHHCCCCC
AGASRREGYIGPATASAPGTPVTVIPVSQGISTTYPITPPRTYGIELQYRFF
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]