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The map label for this gene is aidB [H]

Identifier: 197105439

GI number: 197105439

Start: 2205896

End: 2207551

Strand: Direct

Name: aidB [H]

Synonym: PHZ_c1976

Alternate gene names: 197105439

Gene position: 2205896-2207551 (Clockwise)

Preceding gene: 197105438

Following gene: 197105442

Centisome position: 55.2

GC content: 72.52

Gene sequence:

>1656_bases
ATGCCCGTCTTCGCCCCCACGACCCAGCTCGCCACCCACGAGGTCCTGAACCAGCCGCCCGAGTTCGCGGGCCGGAACCT
CTACGAGATCGACGTCGCCTTCCGCGAGGCCGCGCGGCGCGAGGCCGGCGAGTGGCTGGACGCGCCGCTTTCGGCCCTGG
GCGCGGCGGTGGGTTCGGAACAGGTGCTGGACTGGGGCGAACAGGCCAACCGCTTCCCGCCCGAACTGGTGACGTTCGAC
CGCTACGGCCGGCGGGTGGACGAGGCCCGGTTCCACCCCGCCTACCACCAGCTCATGGCCCTCGCCATGGAGCACCGGAT
CCACGACATCGCCTGGACTGCGGAACGGCCGGGCGGCCACGTCGGCCACCTGGCGACCCTGGCCCTGTTCACCCAGGCCG
AGGCCGGGGTCATGTGCCCGATCAACATGACCTACGCCGCCGTTCCGGCCCTGCGCACCCAGCCCGACGTGACCGGGCCG
TGGCTCGATAAGCTGCTGGGCGGCCGCTACGACGCCCCGCTGAGGCCCATCGGGCAGAAGGCGGGGATCACCGTCGGCAT
GGCCATGACCGAGAAGCAGGGCGGCAGCGACGTGCGGGCCAACACCACCCGCGCCTACCGGCTGGAAACCGGCGATCCGC
GCGCCTATCGCCTCGTCGGCCACAAGTGGTTCTGCTCGGCGCCGATGAGCGACGGCTTCCTGACGCTGGCCTACGCCGAG
CGCGGCCTGTCGTGCTTCCTCGTCCCGCGCATCACGCCCGACGGGGAACGCAACGGCATCCGGGTGATGCGGCTGAAGGA
CAAGCTGGGCAACAAGTCCAACGCCTCCAGCGAGATCGAGTACCACGACGCCTACGCCCAGCTCCTCGGCGACGAGGGCG
AAGGGGTGAAGGTGATCATCGACATGGTCCACCACACGCGGCTCGGCACCATGGGCGGCACCCTGGGGATCATGCGCATG
GCCCTGGCCCAGGCGGTGAACCAGGTGAGCGGGCGCCGGGCGTTCCAGAAGACCCTGATCGACCAGCCGGCGATGACCTC
GGTGATCGCCGACCTGGCGGTCGAGTACGAGGCGGCGGCGGCGCTCTCGATGCGCGTGGCCCGCGCCTTCGACGCCGAGG
ATCCGGCCGGCCGCGCCTTCGCCCGCCTCTCGGTGGCGGTCGGCAAGTACTGGCTGACCAAGCGCAACCCGAACTTCGTC
TACGAGTGCATGGAGTGCCACGGGGGCGTCGGCTACGTGGAGGAGACCCCCATGCCGCGCCTGTTCCGGGAGAGCCCGCT
GAACGCGATCTGGGAGGGCTCGGGCAACGTCATCGCCCTCGACATCCTGCGCACCCTGGGGCGCGAGCCCCTGGCGCTGG
AGGCCTACGCCGCCGAGGTCGCCGAGGCCCGGGGCGCGGACCGGCGGCTGGACGCTGCGGCCGAGGGGTTGCTGGACGGC
CTGGCGCGCCATCGCCCCGGAGAGGCCGACGCGCGCCGGACCGCCGAGCGGATGGCGCTGGTGCTGCAGGGCGCGCTGCT
GGTCCGCCACGCGCCGGCCGCCGTCGCCGACGCCTTCTGCGCCACCCGGCTGGGGGACGAGGGCGGCCGCTCGTTCGGGA
TCCTGCCCGGCGGCGCGGACGTGGCGGCCATCGTGGACCGCCAGCGGTTCGACTAA

Upstream 100 bases:

>100_bases
GTTTGGGCCGCGCTGGCCTTCGGCCACCCCTGGCTGTTCGGCGTCCCCGCCCTCCCCTGACGGCCTTGAAGTGGCCGACG
GGCGGGAGTGGAATGGGTCC

Downstream 100 bases:

>100_bases
GCCTCGGCTAGGCCCCTAGCGCGAACTCCACCGCCGCCTCGCAGTGGGCCACGGCGCTGTCGACCGTGGGCAGCGCCATG
TCGGCCGGATCGAGCAGGAG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MPVFAPTTQLATHEVLNQPPEFAGRNLYEIDVAFREAARREAGEWLDAPLSALGAAVGSEQVLDWGEQANRFPPELVTFD
RYGRRVDEARFHPAYHQLMALAMEHRIHDIAWTAERPGGHVGHLATLALFTQAEAGVMCPINMTYAAVPALRTQPDVTGP
WLDKLLGGRYDAPLRPIGQKAGITVGMAMTEKQGGSDVRANTTRAYRLETGDPRAYRLVGHKWFCSAPMSDGFLTLAYAE
RGLSCFLVPRITPDGERNGIRVMRLKDKLGNKSNASSEIEYHDAYAQLLGDEGEGVKVIIDMVHHTRLGTMGGTLGIMRM
ALAQAVNQVSGRRAFQKTLIDQPAMTSVIADLAVEYEAAAALSMRVARAFDAEDPAGRAFARLSVAVGKYWLTKRNPNFV
YECMECHGGVGYVEETPMPRLFRESPLNAIWEGSGNVIALDILRTLGREPLALEAYAAEVAEARGADRRLDAAAEGLLDG
LARHRPGEADARRTAERMALVLQGALLVRHAPAAVADAFCATRLGDEGGRSFGILPGGADVAAIVDRQRFD

Sequences:

>Translated_551_residues
MPVFAPTTQLATHEVLNQPPEFAGRNLYEIDVAFREAARREAGEWLDAPLSALGAAVGSEQVLDWGEQANRFPPELVTFD
RYGRRVDEARFHPAYHQLMALAMEHRIHDIAWTAERPGGHVGHLATLALFTQAEAGVMCPINMTYAAVPALRTQPDVTGP
WLDKLLGGRYDAPLRPIGQKAGITVGMAMTEKQGGSDVRANTTRAYRLETGDPRAYRLVGHKWFCSAPMSDGFLTLAYAE
RGLSCFLVPRITPDGERNGIRVMRLKDKLGNKSNASSEIEYHDAYAQLLGDEGEGVKVIIDMVHHTRLGTMGGTLGIMRM
ALAQAVNQVSGRRAFQKTLIDQPAMTSVIADLAVEYEAAAALSMRVARAFDAEDPAGRAFARLSVAVGKYWLTKRNPNFV
YECMECHGGVGYVEETPMPRLFRESPLNAIWEGSGNVIALDILRTLGREPLALEAYAAEVAEARGADRRLDAAAEGLLDG
LARHRPGEADARRTAERMALVLQGALLVRHAPAAVADAFCATRLGDEGGRSFGILPGGADVAAIVDRQRFD
>Mature_550_residues
PVFAPTTQLATHEVLNQPPEFAGRNLYEIDVAFREAARREAGEWLDAPLSALGAAVGSEQVLDWGEQANRFPPELVTFDR
YGRRVDEARFHPAYHQLMALAMEHRIHDIAWTAERPGGHVGHLATLALFTQAEAGVMCPINMTYAAVPALRTQPDVTGPW
LDKLLGGRYDAPLRPIGQKAGITVGMAMTEKQGGSDVRANTTRAYRLETGDPRAYRLVGHKWFCSAPMSDGFLTLAYAER
GLSCFLVPRITPDGERNGIRVMRLKDKLGNKSNASSEIEYHDAYAQLLGDEGEGVKVIIDMVHHTRLGTMGGTLGIMRMA
LAQAVNQVSGRRAFQKTLIDQPAMTSVIADLAVEYEAAAALSMRVARAFDAEDPAGRAFARLSVAVGKYWLTKRNPNFVY
ECMECHGGVGYVEETPMPRLFRESPLNAIWEGSGNVIALDILRTLGREPLALEAYAAEVAEARGADRRLDAAAEGLLDGL
ARHRPGEADARRTAERMALVLQGALLVRHAPAAVADAFCATRLGDEGGRSFGILPGGADVAAIVDRQRFD

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=260, Percent_Identity=28.4615384615385, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4557233, Length=272, Percent_Identity=30.1470588235294, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI226958412, Length=302, Percent_Identity=27.1523178807947, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI226958414, Length=302, Percent_Identity=27.1523178807947, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI4501857, Length=281, Percent_Identity=26.3345195729537, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI7656849, Length=270, Percent_Identity=24.8148148148148, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI4557235, Length=370, Percent_Identity=23.2432432432432, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI76496475, Length=370, Percent_Identity=23.2432432432432, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87082384, Length=521, Percent_Identity=45.10556621881, Blast_Score=432, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI86563383, Length=508, Percent_Identity=32.2834645669291, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI86563381, Length=508, Percent_Identity=32.2834645669291, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=260, Percent_Identity=28.0769230769231, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17538396, Length=272, Percent_Identity=27.9411764705882, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=272, Percent_Identity=24.6323529411765, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=276, Percent_Identity=25.7246376811594, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=276, Percent_Identity=23.5507246376812, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=191, Percent_Identity=28.2722513089005, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=271, Percent_Identity=24.3542435424354, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17534899, Length=276, Percent_Identity=22.8260869565217, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356377, Length=328, Percent_Identity=26.219512195122, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24646207, Length=275, Percent_Identity=26.5454545454545, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666513, Length=272, Percent_Identity=24.6323529411765, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI281363737, Length=370, Percent_Identity=25.6756756756757, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355753, Length=406, Percent_Identity=23.6453201970443, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59997; Mature: 59866

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVFAPTTQLATHEVLNQPPEFAGRNLYEIDVAFREAARREAGEWLDAPLSALGAAVGSE
CCCCCCCHHHHHHHHHCCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QVLDWGEQANRFPPELVTFDRYGRRVDEARFHPAYHQLMALAMEHRIHDIAWTAERPGGH
HHHHHHHHHCCCCCHHEEHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCC
VGHLATLALFTQAEAGVMCPINMTYAAVPALRTQPDVTGPWLDKLLGGRYDAPLRPIGQK
HHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
AGITVGMAMTEKQGGSDVRANTTRAYRLETGDPRAYRLVGHKWFCSAPMSDGFLTLAYAE
CCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEECCEEEECCCCCCCCEEEEEHH
RGLSCFLVPRITPDGERNGIRVMRLKDKLGNKSNASSEIEYHDAYAQLLGDEGEGVKVII
CCCEEEEEECCCCCCCCCCEEEEEEHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
DMVHHTRLGTMGGTLGIMRMALAQAVNQVSGRRAFQKTLIDQPAMTSVIADLAVEYEAAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ALSMRVARAFDAEDPAGRAFARLSVAVGKYWLTKRNPNFVYECMECHGGVGYVEETPMPR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCCCCCCCCCCCH
LFRESPLNAIWEGSGNVIALDILRTLGREPLALEAYAAEVAEARGADRRLDAAAEGLLDG
HHHHCCCCEEECCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LARHRPGEADARRTAERMALVLQGALLVRHAPAAVADAFCATRLGDEGGRSFGILPGGAD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCC
VAAIVDRQRFD
HHHHHHHHCCC
>Mature Secondary Structure 
PVFAPTTQLATHEVLNQPPEFAGRNLYEIDVAFREAARREAGEWLDAPLSALGAAVGSE
CCCCCCHHHHHHHHHCCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QVLDWGEQANRFPPELVTFDRYGRRVDEARFHPAYHQLMALAMEHRIHDIAWTAERPGGH
HHHHHHHHHCCCCCHHEEHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCC
VGHLATLALFTQAEAGVMCPINMTYAAVPALRTQPDVTGPWLDKLLGGRYDAPLRPIGQK
HHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
AGITVGMAMTEKQGGSDVRANTTRAYRLETGDPRAYRLVGHKWFCSAPMSDGFLTLAYAE
CCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEECCEEEECCCCCCCCEEEEEHH
RGLSCFLVPRITPDGERNGIRVMRLKDKLGNKSNASSEIEYHDAYAQLLGDEGEGVKVII
CCCEEEEEECCCCCCCCCCEEEEEEHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
DMVHHTRLGTMGGTLGIMRMALAQAVNQVSGRRAFQKTLIDQPAMTSVIADLAVEYEAAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ALSMRVARAFDAEDPAGRAFARLSVAVGKYWLTKRNPNFVYECMECHGGVGYVEETPMPR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCCCCCCCCCCCH
LFRESPLNAIWEGSGNVIALDILRTLGREPLALEAYAAEVAEARGADRRLDAAAEGLLDG
HHHHCCCCEEECCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LARHRPGEADARRTAERMALVLQGALLVRHAPAAVADAFCATRLGDEGGRSFGILPGGAD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCC
VAAIVDRQRFD
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]