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The map label for this gene is era [H]

Identifier: 197105332

GI number: 197105332

Start: 2096942

End: 2097922

Strand: Reverse

Name: era [H]

Synonym: PHZ_c1869

Alternate gene names: 197105332

Gene position: 2097922-2096942 (Counterclockwise)

Preceding gene: 197105333

Following gene: 197105331

Centisome position: 52.5

GC content: 69.52

Gene sequence:

>981_bases
GTGCATGCTGCTGAAGCGCGAAGGGCCCGAGCCCGGAAAGGTCGGAGAATGAGCCGCGCCGGTTTCTGCGCCATCATCGG
CGCGCCCAATGCGGGCAAGTCCACCCTGACCAACCGACTGGTCGGGGCCAAGGTCTCGATCGTCACCCAGAAGGTGCAGA
CGACGCGCTTTCCCGTGCGCGGCGTGGCCATCGCGGGCGACGCCCAGATCGTGCTGGTCGACACCCCCGGGATCTTCCAG
CCGCGCCGCCGGCTGGACCGGGCCATGGTCCGCGCCGCCTGGGGCGGGGCCGAGGACGCCGACGCCGTCGTCCACCTGGT
CGACGCCGCCGCCCAACTCGGCGACAAGCCCGCCGACCGCAAGGCCCAGGCCGACGTGGACTCCATCGTCGAGGGCCTGA
AGAAATCCGGCCGTAAGGTGATCCTGGCGCTGAACAAGATCGACGCGGTCAAGCGCGAGGCGCTGCTCGATATCTCCAAA
ACCCTCTTCGATACGGGCGTTTACGACGAGGTCTTCATGGTCTCGGCGACCTCCGGCTCGGGCGTGGAGGACCTGAAGGC
CAGGCTCGCGGCCCTGATGCCCGACAACCCCTGGTTCTACCCCGAGGACCAGACCGCCGACCTGCCGGCCCGCCTGCTGG
CGGCCGAGATCACCCGCGAGAAGCTCTACCTGCGCCTGCACGAGGAGCTGCCCTATTCGGCCACCGTCGAGACGACGAAG
TTCGAGGAGAGGCCCGCGCCCCCCGACGGCGACGGCGGCGTGCGCATCGAGCAGACCATCTTCGTCGAGCGCGAGGGCCA
GCGGCCCATCGTCCTGGGCAAGGGCGGCCAGACCCTGAAGTGGATCGGCCAGAAGGCCCGCGAGGAGCTGACCGCCATTC
TCGACCGCCCCGTGCACCTCTTCCTGCACGTGGCCGTGGACGAGCGCTGGGCCGACAAGCGCGAGTTCTACGGCCCGCTG
GGCCTGGACTACGACGTGTGA

Upstream 100 bases:

>100_bases
CGCACGCCCCGTCCTTCACGGTCGAGGTGCAGGTGGCGGGCTTCGGCGCCGAGCGCGGCGAGGGCCGCTCGCGCCAGGCC
GCCGAGAAGGCCGCGGCCCA

Downstream 100 bases:

>100_bases
GAGCCTAGCTCTCACCAGATGGTCGACCTCGACGCCTACTTCGCCCGCATCGGCTACGCCGGCTCTCGCGAGCCGACGCT
TCAGACCCTGCGCGAGCTGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MHAAEARRARARKGRRMSRAGFCAIIGAPNAGKSTLTNRLVGAKVSIVTQKVQTTRFPVRGVAIAGDAQIVLVDTPGIFQ
PRRRLDRAMVRAAWGGAEDADAVVHLVDAAAQLGDKPADRKAQADVDSIVEGLKKSGRKVILALNKIDAVKREALLDISK
TLFDTGVYDEVFMVSATSGSGVEDLKARLAALMPDNPWFYPEDQTADLPARLLAAEITREKLYLRLHEELPYSATVETTK
FEERPAPPDGDGGVRIEQTIFVEREGQRPIVLGKGGQTLKWIGQKAREELTAILDRPVHLFLHVAVDERWADKREFYGPL
GLDYDV

Sequences:

>Translated_326_residues
MHAAEARRARARKGRRMSRAGFCAIIGAPNAGKSTLTNRLVGAKVSIVTQKVQTTRFPVRGVAIAGDAQIVLVDTPGIFQ
PRRRLDRAMVRAAWGGAEDADAVVHLVDAAAQLGDKPADRKAQADVDSIVEGLKKSGRKVILALNKIDAVKREALLDISK
TLFDTGVYDEVFMVSATSGSGVEDLKARLAALMPDNPWFYPEDQTADLPARLLAAEITREKLYLRLHEELPYSATVETTK
FEERPAPPDGDGGVRIEQTIFVEREGQRPIVLGKGGQTLKWIGQKAREELTAILDRPVHLFLHVAVDERWADKREFYGPL
GLDYDV
>Mature_326_residues
MHAAEARRARARKGRRMSRAGFCAIIGAPNAGKSTLTNRLVGAKVSIVTQKVQTTRFPVRGVAIAGDAQIVLVDTPGIFQ
PRRRLDRAMVRAAWGGAEDADAVVHLVDAAAQLGDKPADRKAQADVDSIVEGLKKSGRKVILALNKIDAVKREALLDISK
TLFDTGVYDEVFMVSATSGSGVEDLKARLAALMPDNPWFYPEDQTADLPARLLAAEITREKLYLRLHEELPYSATVETTK
FEERPAPPDGDGGVRIEQTIFVEREGQRPIVLGKGGQTLKWIGQKAREELTAILDRPVHLFLHVAVDERWADKREFYGPL
GLDYDV

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=324, Percent_Identity=28.3950617283951, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI1788919, Length=308, Percent_Identity=37.012987012987, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI87082120, Length=172, Percent_Identity=31.3953488372093, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646434, Length=334, Percent_Identity=25.1497005988024, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35827; Mature: 35827

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAAEARRARARKGRRMSRAGFCAIIGAPNAGKSTLTNRLVGAKVSIVTQKVQTTRFPVR
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCC
GVAIAGDAQIVLVDTPGIFQPRRRLDRAMVRAAWGGAEDADAVVHLVDAAAQLGDKPADR
EEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
KAQADVDSIVEGLKKSGRKVILALNKIDAVKREALLDISKTLFDTGVYDEVFMVSATSGS
HHHCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GVEDLKARLAALMPDNPWFYPEDQTADLPARLLAAEITREKLYLRLHEELPYSATVETTK
CHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
FEERPAPPDGDGGVRIEQTIFVEREGQRPIVLGKGGQTLKWIGQKAREELTAILDRPVHL
CCCCCCCCCCCCCEEEEEEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEE
FLHVAVDERWADKREFYGPLGLDYDV
EEEEECCHHHCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHAAEARRARARKGRRMSRAGFCAIIGAPNAGKSTLTNRLVGAKVSIVTQKVQTTRFPVR
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCC
GVAIAGDAQIVLVDTPGIFQPRRRLDRAMVRAAWGGAEDADAVVHLVDAAAQLGDKPADR
EEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
KAQADVDSIVEGLKKSGRKVILALNKIDAVKREALLDISKTLFDTGVYDEVFMVSATSGS
HHHCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GVEDLKARLAALMPDNPWFYPEDQTADLPARLLAAEITREKLYLRLHEELPYSATVETTK
CHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
FEERPAPPDGDGGVRIEQTIFVEREGQRPIVLGKGGQTLKWIGQKAREELTAILDRPVHL
CCCCCCCCCCCCCEEEEEEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEE
FLHVAVDERWADKREFYGPLGLDYDV
EEEEECCHHHCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA