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The map label for this gene is nrdJ [H]

Identifier: 197105318

GI number: 197105318

Start: 2076703

End: 2079207

Strand: Direct

Name: nrdJ [H]

Synonym: PHZ_c1855

Alternate gene names: 197105318

Gene position: 2076703-2079207 (Clockwise)

Preceding gene: 197105315

Following gene: 197105319

Centisome position: 51.97

GC content: 75.09

Gene sequence:

>2505_bases
ATGGGCGATCAAGCCTCGCGCGTGGGAATCGAAGGCCGCCTGCTCGAGCGGCCCCAAGGCGTCGTCGAGGTCGAGGCGCC
GGCGCACTGGAGCAGCGCCCGGGTCGAGGCCTGGCTGGACTGGGCAGGCGGGCGTCCCGACCTGCCGGCGGCCATCGTCG
ATCAAGCGGCCGCCCTCACCGCCAATGCGCAGGCCGCGGGCCTGCTGAAGGATCTGCGCGCCCGCACCCATTTCCGCGAG
GCGCTCACCGAGGCGATGCTGCTGGGCGCCGTCGCCCTGGCCCCCGCCCCCTCCGTCGCCCCTCTCGCGACCGCCGACGC
CGGCGCTCCGGACTTCCTCCGCAGCGTGCAGGCGTTCGAGAGCCGGTTCCGCGCCGATCAGGCCGCGGAGGCCGCCGCCC
GGCTGCTGGCGGCCCGGCTCCAGGCGGTGATGGACTCGATCCTGCGCTGCGAAGGCGACGCCGAGGCCTGCGCGGATCCG
GCCCGGAACAGCAGCCTGGCCCGCGCCGCCGAGGCCGCCCGCGCGGCCGGCGCCGCGGACGCGATGATCCTGGAGGCCAT
CGCTCTCGCGGGCGCCGGCGAGAGCGCGTGGCCCGCCCCGCCCGAGGCCGAGCCGCCGACCGCCAAGGGGCTCGTCGTCC
GCCTCGACGCCTTCGACGGACCCGCTGGGGCGGCGACGGCGCGAGCCGCCTGGACCACGGGTCACGTCCTGGTCGCCCGG
ACGCCCGCCGACACCGAGGCCCTGATGGCGCTCGCCGCAGCGCCGCGGGGGGGCGTCGACCTCATGGCGTTCTTCGGCGA
GACCGGCTTCGACTGGGACGTCTTCGAGGGCGCGGTGCAGCTCGCCGCCACTGCGCTCGCCGCGAACGGCGGGTCCGGCC
TCCTCGCGCTGGCGAACCTGGGGGACTGGCTGGCGGCGCAGGGATACGCCTACGACAGCGACGGGGGAAGGACCGCCGCC
CGCCAGCTCTACGAACGGGCTCGCGCCGCGCTCGACGAGACCGGGCTCGGCGAGACCGGGCCGGCGTGCCGGCTGGCGGC
GCTGAGCGATCCGGAGCTCGCGCTGCGACTGGGCGGCCCGCTCGACGCCGGGCCGTGGCTGGGGCCGATCACCGCGGCCG
AGACGGCCGACGGCGAAGTCTTGCGGGTCCTCTCGGATGCGGCGCTGCGCGCGCTTGCGGCCACGAACGCGGACCGGGAC
GCGGTGGAGGCGGCCTGCCTGGGCCGCCGCAGCCTGACCGACGCGCCGGGCGTGAACCTCCAGTCCCTCGCCGCCTGCGG
CTTCTCGGACCTTGAGATCGGCGCCGCCATCGCCGAGCTGCCCTTCGTGGGCCGGCTCGCCGAAGCGTTCGCGCCCGCCG
TGCTCGGCGAAGGCTTCCTGCGGGACGTGCTCGGCGCGAGCCCCGAGCAGCTCGCCGACCCCGGCTTGGACGTGCTCGCC
CTGGCCGGGTTCTCGTCCGAGGATGTCGCCGCCGCCGAGCGCCACGTCCTCGGGGGCGACGGCCTCGAGGGCGCGCCGGG
CCTGACCGAGGCCCAGCAGGCGGTCTTCCGATCCCGCGACGAGACCGGTCCGGCGGCCGTCGCGGCCATGATGCAGGCCT
TGCGCCCCGCCCTGGGCGTTCCGCCGGTGCTGGAGGTGGTCCTGCCGTGGCGGGCCACGCCGGGGGACGTGCTGGCGGCG
ATGGAGGCTGCGGAGGCGCCGGTGCGCGTGCGACGGGAGCCTGCGCCTGCGGACGCCGTGCTCGACCTGCCCGCCTTCGC
CGACCTGCCCGATCGCCGCGGACCCGCGTCCGAGCCCGAGGAACGCATCGTCGAGCGTATCGTCGAGCGCGACCGGACTC
GCCGCAAGCTGCCCGACCGCCGCAAGGGCTACATCCAGAAAGCCTCGGTCGGCGGCCACAAGGTCTACATCCACACCGGC
GAGTATGACGACGGCGAGCTCGGCGAGATCTTCATCGACATGCACAAGGAAGGCGCGGCCTTCCGCTCGCTGATGAACAA
CTTCGCGATCGCGATCTCCATCGGCCTGCAGTACGGCGTGCCGCTGGACGAGTTCGTGGACGCCTTCGTCTTCACGCGCT
TCGAGCCCGCCGGACCGGTTACGGGCAACGACTCGGTGAAGTCGGCCACGTCCATCCTCGACTACATCTTCCGTGAGCTC
GGGATCAGCTACCTGGGCCGCGCGGACCTCGCCAGCGCCGACCCTGGCGAGCTGAACGCCGACGGACTGGGACGGGGCAA
GGCCGACGACGACGGCGACCCGGGCCTGGGCCCCGAGGTCCCGCAGCCGGCGTCGCGCTTCATCTCGCGCGGATTCTCCC
GCGGCTCGACCCCCGACAACCTCGTCTTCCTGCCCACCGCCAACCGGAACGCCGGCCCGGCGGCTCTGGAGGCGGCCGAA
GTCTGCGCGGCCTGCGGCGACATCGCGGTCGTGCGCAAGGGCCAGGCGATGATCTGCGAGACCTGCGGCTCGCGGGCGGG
CCGCGCCGAGGATCAGGCGCGCTAA

Upstream 100 bases:

>100_bases
TCTTCCGAGTCGATATGTTGGGGATGACTGCCCTCTCGACCCCAACATCTATTGCCGTTGGCCGCTGGGCGGCCCTACCC
TGCCCGCAGGGGAGTCGATG

Downstream 100 bases:

>100_bases
GTCCCTCTAAGTTACCGCGATTTAAGTGGTGTTCGGCGTCCCGCCAGCGCAGAGGTGACGCCGGACTCCTGAGAGGATCG
CCCCTGTGACGACGCGTTCC

Product: ribonucleotide reductase-related protein

Products: NA

Alternate protein names: Ribonucleoside-diphosphate reductase nrdJ [H]

Number of amino acids: Translated: 834; Mature: 833

Protein sequence:

>834_residues
MGDQASRVGIEGRLLERPQGVVEVEAPAHWSSARVEAWLDWAGGRPDLPAAIVDQAAALTANAQAAGLLKDLRARTHFRE
ALTEAMLLGAVALAPAPSVAPLATADAGAPDFLRSVQAFESRFRADQAAEAAARLLAARLQAVMDSILRCEGDAEACADP
ARNSSLARAAEAARAAGAADAMILEAIALAGAGESAWPAPPEAEPPTAKGLVVRLDAFDGPAGAATARAAWTTGHVLVAR
TPADTEALMALAAAPRGGVDLMAFFGETGFDWDVFEGAVQLAATALAANGGSGLLALANLGDWLAAQGYAYDSDGGRTAA
RQLYERARAALDETGLGETGPACRLAALSDPELALRLGGPLDAGPWLGPITAAETADGEVLRVLSDAALRALAATNADRD
AVEAACLGRRSLTDAPGVNLQSLAACGFSDLEIGAAIAELPFVGRLAEAFAPAVLGEGFLRDVLGASPEQLADPGLDVLA
LAGFSSEDVAAAERHVLGGDGLEGAPGLTEAQQAVFRSRDETGPAAVAAMMQALRPALGVPPVLEVVLPWRATPGDVLAA
MEAAEAPVRVRREPAPADAVLDLPAFADLPDRRGPASEPEERIVERIVERDRTRRKLPDRRKGYIQKASVGGHKVYIHTG
EYDDGELGEIFIDMHKEGAAFRSLMNNFAIAISIGLQYGVPLDEFVDAFVFTRFEPAGPVTGNDSVKSATSILDYIFREL
GISYLGRADLASADPGELNADGLGRGKADDDGDPGLGPEVPQPASRFISRGFSRGSTPDNLVFLPTANRNAGPAALEAAE
VCAACGDIAVVRKGQAMICETCGSRAGRAEDQAR

Sequences:

>Translated_834_residues
MGDQASRVGIEGRLLERPQGVVEVEAPAHWSSARVEAWLDWAGGRPDLPAAIVDQAAALTANAQAAGLLKDLRARTHFRE
ALTEAMLLGAVALAPAPSVAPLATADAGAPDFLRSVQAFESRFRADQAAEAAARLLAARLQAVMDSILRCEGDAEACADP
ARNSSLARAAEAARAAGAADAMILEAIALAGAGESAWPAPPEAEPPTAKGLVVRLDAFDGPAGAATARAAWTTGHVLVAR
TPADTEALMALAAAPRGGVDLMAFFGETGFDWDVFEGAVQLAATALAANGGSGLLALANLGDWLAAQGYAYDSDGGRTAA
RQLYERARAALDETGLGETGPACRLAALSDPELALRLGGPLDAGPWLGPITAAETADGEVLRVLSDAALRALAATNADRD
AVEAACLGRRSLTDAPGVNLQSLAACGFSDLEIGAAIAELPFVGRLAEAFAPAVLGEGFLRDVLGASPEQLADPGLDVLA
LAGFSSEDVAAAERHVLGGDGLEGAPGLTEAQQAVFRSRDETGPAAVAAMMQALRPALGVPPVLEVVLPWRATPGDVLAA
MEAAEAPVRVRREPAPADAVLDLPAFADLPDRRGPASEPEERIVERIVERDRTRRKLPDRRKGYIQKASVGGHKVYIHTG
EYDDGELGEIFIDMHKEGAAFRSLMNNFAIAISIGLQYGVPLDEFVDAFVFTRFEPAGPVTGNDSVKSATSILDYIFREL
GISYLGRADLASADPGELNADGLGRGKADDDGDPGLGPEVPQPASRFISRGFSRGSTPDNLVFLPTANRNAGPAALEAAE
VCAACGDIAVVRKGQAMICETCGSRAGRAEDQAR
>Mature_833_residues
GDQASRVGIEGRLLERPQGVVEVEAPAHWSSARVEAWLDWAGGRPDLPAAIVDQAAALTANAQAAGLLKDLRARTHFREA
LTEAMLLGAVALAPAPSVAPLATADAGAPDFLRSVQAFESRFRADQAAEAAARLLAARLQAVMDSILRCEGDAEACADPA
RNSSLARAAEAARAAGAADAMILEAIALAGAGESAWPAPPEAEPPTAKGLVVRLDAFDGPAGAATARAAWTTGHVLVART
PADTEALMALAAAPRGGVDLMAFFGETGFDWDVFEGAVQLAATALAANGGSGLLALANLGDWLAAQGYAYDSDGGRTAAR
QLYERARAALDETGLGETGPACRLAALSDPELALRLGGPLDAGPWLGPITAAETADGEVLRVLSDAALRALAATNADRDA
VEAACLGRRSLTDAPGVNLQSLAACGFSDLEIGAAIAELPFVGRLAEAFAPAVLGEGFLRDVLGASPEQLADPGLDVLAL
AGFSSEDVAAAERHVLGGDGLEGAPGLTEAQQAVFRSRDETGPAAVAAMMQALRPALGVPPVLEVVLPWRATPGDVLAAM
EAAEAPVRVRREPAPADAVLDLPAFADLPDRRGPASEPEERIVERIVERDRTRRKLPDRRKGYIQKASVGGHKVYIHTGE
YDDGELGEIFIDMHKEGAAFRSLMNNFAIAISIGLQYGVPLDEFVDAFVFTRFEPAGPVTGNDSVKSATSILDYIFRELG
ISYLGRADLASADPGELNADGLGRGKADDDGDPGLGPEVPQPASRFISRGFSRGSTPDNLVFLPTANRNAGPAALEAAEV
CAACGDIAVVRKGQAMICETCGSRAGRAEDQAR

Specific function: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen [H]

COG id: COG0209

COG function: function code F; Ribonucleotide reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase class-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002876
- InterPro:   IPR017856
- InterPro:   IPR013344
- InterPro:   IPR000788
- InterPro:   IPR013678 [H]

Pfam domain/function: PF08471 Ribonuc_red_2_N; PF02867 Ribonuc_red_lgC [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 86279; Mature: 86147

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDQASRVGIEGRLLERPQGVVEVEAPAHWSSARVEAWLDWAGGRPDLPAAIVDQAAALT
CCCCCCCCCCCCHHHCCCCCCEEEECCCCCCCHHHHHHEECCCCCCCCCHHHHHHHHHHH
ANAQAAGLLKDLRARTHFREALTEAMLLGAVALAPAPSVAPLATADAGAPDFLRSVQAFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
SRFRADQAAEAAARLLAARLQAVMDSILRCEGDAEACADPARNSSLARAAEAARAAGAAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCHHH
AMILEAIALAGAGESAWPAPPEAEPPTAKGLVVRLDAFDGPAGAATARAAWTTGHVLVAR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHEECCCCEEEEE
TPADTEALMALAAAPRGGVDLMAFFGETGFDWDVFEGAVQLAATALAANGGSGLLALANL
CCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
GDWLAAQGYAYDSDGGRTAARQLYERARAALDETGLGETGPACRLAALSDPELALRLGGP
CHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEECCC
LDAGPWLGPITAAETADGEVLRVLSDAALRALAATNADRDAVEAACLGRRSLTDAPGVNL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCH
QSLAACGFSDLEIGAAIAELPFVGRLAEAFAPAVLGEGFLRDVLGASPEQLADPGLDVLA
HHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEE
LAGFSSEDVAAAERHVLGGDGLEGAPGLTEAQQAVFRSRDETGPAAVAAMMQALRPALGV
ECCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
PPVLEVVLPWRATPGDVLAAMEAAEAPVRVRREPAPADAVLDLPAFADLPDRRGPASEPE
CHHHHHHCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCHH
ERIVERIVERDRTRRKLPDRRKGYIQKASVGGHKVYIHTGEYDDGELGEIFIDMHKEGAA
HHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCEEEEEECCCCCCCCCCCEEEEHHHCCHH
FRSLMNNFAIAISIGLQYGVPLDEFVDAFVFTRFEPAGPVTGNDSVKSATSILDYIFREL
HHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GISYLGRADLASADPGELNADGLGRGKADDDGDPGLGPEVPQPASRFISRGFSRGSTPDN
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
LVFLPTANRNAGPAALEAAEVCAACGDIAVVRKGQAMICETCGSRAGRAEDQAR
EEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GDQASRVGIEGRLLERPQGVVEVEAPAHWSSARVEAWLDWAGGRPDLPAAIVDQAAALT
CCCCCCCCCCCHHHCCCCCCEEEECCCCCCCHHHHHHEECCCCCCCCCHHHHHHHHHHH
ANAQAAGLLKDLRARTHFREALTEAMLLGAVALAPAPSVAPLATADAGAPDFLRSVQAFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
SRFRADQAAEAAARLLAARLQAVMDSILRCEGDAEACADPARNSSLARAAEAARAAGAAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCHHH
AMILEAIALAGAGESAWPAPPEAEPPTAKGLVVRLDAFDGPAGAATARAAWTTGHVLVAR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHEECCCCEEEEE
TPADTEALMALAAAPRGGVDLMAFFGETGFDWDVFEGAVQLAATALAANGGSGLLALANL
CCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
GDWLAAQGYAYDSDGGRTAARQLYERARAALDETGLGETGPACRLAALSDPELALRLGGP
CHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEECCC
LDAGPWLGPITAAETADGEVLRVLSDAALRALAATNADRDAVEAACLGRRSLTDAPGVNL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCH
QSLAACGFSDLEIGAAIAELPFVGRLAEAFAPAVLGEGFLRDVLGASPEQLADPGLDVLA
HHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEE
LAGFSSEDVAAAERHVLGGDGLEGAPGLTEAQQAVFRSRDETGPAAVAAMMQALRPALGV
ECCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
PPVLEVVLPWRATPGDVLAAMEAAEAPVRVRREPAPADAVLDLPAFADLPDRRGPASEPE
CHHHHHHCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCHH
ERIVERIVERDRTRRKLPDRRKGYIQKASVGGHKVYIHTGEYDDGELGEIFIDMHKEGAA
HHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCEEEEEECCCCCCCCCCCEEEEHHHCCHH
FRSLMNNFAIAISIGLQYGVPLDEFVDAFVFTRFEPAGPVTGNDSVKSATSILDYIFREL
HHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GISYLGRADLASADPGELNADGLGRGKADDDGDPGLGPEVPQPASRFISRGFSRGSTPDN
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
LVFLPTANRNAGPAALEAAEVCAACGDIAVVRKGQAMICETCGSRAGRAEDQAR
EEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]