Click here to switch to the map view.

The map label for this gene is uppS [H]

Identifier: 197105239

GI number: 197105239

Start: 1987300

End: 1988076

Strand: Reverse

Name: uppS [H]

Synonym: PHZ_c1776

Alternate gene names: 197105239

Gene position: 1988076-1987300 (Counterclockwise)

Preceding gene: 197105240

Following gene: 197105238

Centisome position: 49.75

GC content: 72.84

Gene sequence:

>777_bases
ATGGCCGCACAAGACAAGACGCCGCCTGCGTCCACGCCCCAGCCGGGCGCGGCGGAGCGGCCCCTGCACGTGGCCATCGT
CATGGACGGCAACGGCCGCTGGGCCAAACGCCGCGGCCTGCCGCGCACCCTCGGGCATCGCGAGGGCGTCGAGGCGCTGA
AGCGCACCGTCTCGGCCGCGGCCGAGCAGGACATCCGCTGGCTGACCGTCTTCGGTTTCTCCACCGAGAACTGGAGCCGG
CCGGCCGCCGAGGTGGCCGAGCTGATGGCCCTGCCGAAGCGCTACTTCGAGAGCGACATCGGCCGGCTCGAGCGGGAAGG
GGTGCGCGTGCGCGTGATCGGCCGCCGAGCCGGCCTCTCGCCCGAACTCGTGCGGATCATCGAGGACGCCGAGACGCGCA
CGGCGCGGAACGACCGGTTCTTCCTGAACATCGCCTTCAACTACGGCGGTCAGGCCGACATCGCCGACGCCGCCCGGCGC
TTCGCCGAGGAGGTGGCCGCCGGCCGCGCCCGGCCGTCCGACCTGGACGAGCGGGTGTTCGCAAGCTTCCTGGCGACCGC
CGGGTCCCCGCCGCCGGACGTGATCATCCGCCCGTCGGGCGAGCAGCGCCTGTCGAACTTCCTCCTATGGGAGGCGGCCT
ACGCGGAGCTCGTCTTCCAGGACGTGCTCTGGCCGGACTACGGGGCCGAACACCTGAAGGCGGCGCTCGCCGCCTTCGCC
GCCCGGGACCGACGCTATGGCGCGATCGTGGCCGATGACGTCCTCGCCGCCGGCTAA

Upstream 100 bases:

>100_bases
CGAGGCCATCAAGCGCATCGACGAAGCCTTGAAAACCAAGGAACAAGAGATCATGCAGGTCTGACGCGCGCGTCAGCCGC
CTCGTAGGATCCCCCACAGC

Downstream 100 bases:

>100_bases
GCGCTTCGACTGGTCCAACCTCGGCCTGCGGATCGCCTCGGCCGTCGTGATCGGGCCGGCCGCGGTCGGCGCGGCCTGGA
TCGGCGGCTGGCCCTATCTC

Product: undecaprenyl diphosphate synthase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAAQDKTPPASTPQPGAAERPLHVAIVMDGNGRWAKRRGLPRTLGHREGVEALKRTVSAAAEQDIRWLTVFGFSTENWSR
PAAEVAELMALPKRYFESDIGRLEREGVRVRVIGRRAGLSPELVRIIEDAETRTARNDRFFLNIAFNYGGQADIADAARR
FAEEVAAGRARPSDLDERVFASFLATAGSPPPDVIIRPSGEQRLSNFLLWEAAYAELVFQDVLWPDYGAEHLKAALAAFA
ARDRRYGAIVADDVLAAG

Sequences:

>Translated_258_residues
MAAQDKTPPASTPQPGAAERPLHVAIVMDGNGRWAKRRGLPRTLGHREGVEALKRTVSAAAEQDIRWLTVFGFSTENWSR
PAAEVAELMALPKRYFESDIGRLEREGVRVRVIGRRAGLSPELVRIIEDAETRTARNDRFFLNIAFNYGGQADIADAARR
FAEEVAAGRARPSDLDERVFASFLATAGSPPPDVIIRPSGEQRLSNFLLWEAAYAELVFQDVLWPDYGAEHLKAALAAFA
ARDRRYGAIVADDVLAAG
>Mature_257_residues
AAQDKTPPASTPQPGAAERPLHVAIVMDGNGRWAKRRGLPRTLGHREGVEALKRTVSAAAEQDIRWLTVFGFSTENWSRP
AAEVAELMALPKRYFESDIGRLEREGVRVRVIGRRAGLSPELVRIIEDAETRTARNDRFFLNIAFNYGGQADIADAARRF
AEEVAAGRARPSDLDERVFASFLATAGSPPPDVIIRPSGEQRLSNFLLWEAAYAELVFQDVLWPDYGAEHLKAALAAFAA
RDRRYGAIVADDVLAAG

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580738, Length=222, Percent_Identity=38.7387387387387, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI45580742, Length=222, Percent_Identity=38.7387387387387, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1786371, Length=242, Percent_Identity=45.4545454545455, Blast_Score=218, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI71993029, Length=224, Percent_Identity=34.8214285714286, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319474, Length=225, Percent_Identity=34.2222222222222, Blast_Score=125, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6323748, Length=242, Percent_Identity=29.3388429752066, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI18857969, Length=230, Percent_Identity=37.3913043478261, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 28382; Mature: 28251

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQDKTPPASTPQPGAAERPLHVAIVMDGNGRWAKRRGLPRTLGHREGVEALKRTVSAA
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHCCCCHHHCHHHHHHHHHHHHHHH
AEQDIRWLTVFGFSTENWSRPAAEVAELMALPKRYFESDIGRLEREGVRVRVIGRRAGLS
HHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
PELVRIIEDAETRTARNDRFFLNIAFNYGGQADIADAARRFAEEVAAGRARPSDLDERVF
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
ASFLATAGSPPPDVIIRPSGEQRLSNFLLWEAAYAELVFQDVLWPDYGAEHLKAALAAFA
HHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ARDRRYGAIVADDVLAAG
HHCCCCCCEEHHHHHHCC
>Mature Secondary Structure 
AAQDKTPPASTPQPGAAERPLHVAIVMDGNGRWAKRRGLPRTLGHREGVEALKRTVSAA
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHCCCCHHHCHHHHHHHHHHHHHHH
AEQDIRWLTVFGFSTENWSRPAAEVAELMALPKRYFESDIGRLEREGVRVRVIGRRAGLS
HHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
PELVRIIEDAETRTARNDRFFLNIAFNYGGQADIADAARRFAEEVAAGRARPSDLDERVF
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
ASFLATAGSPPPDVIIRPSGEQRLSNFLLWEAAYAELVFQDVLWPDYGAEHLKAALAAFA
HHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ARDRRYGAIVADDVLAAG
HHCCCCCCEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]