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The map label for this gene is frpA [H]

Identifier: 197105012

GI number: 197105012

Start: 1748008

End: 1749321

Strand: Reverse

Name: frpA [H]

Synonym: PHZ_c1549

Alternate gene names: 197105012

Gene position: 1749321-1748008 (Counterclockwise)

Preceding gene: 197105013

Following gene: 197105011

Centisome position: 43.77

GC content: 69.18

Gene sequence:

>1314_bases
ATGTCGATCATCATCAGCTTCGGGGGCGTCCCCGACGGCGCGTTCAACCTCTACGAGGAAGCGGGCTTCCGGTTCACGAC
GGCCACCAACGCCCCCGACGCCTTCGAGGGCGGCCTGAGCATCGCCGACCTCGGCACGGGCGAATACATCTTCGTGCGCA
ACACGGCCGACACCGCCACGGTCGAGAAGCTGGACGGCGGCGCGTTCGGCGTGAGTTCGGTCGATCTCGACGGCTTCCGC
TGGACCGGCTTCACGCCGGCCGGGGAGCCCATCCCCGGCTCGTCCGCGGTCCAGATCAACTTCATCGGCTACAAGAGCGA
CGGGACGACGGTCAGCTGGTCGTTCAGCACCGACGCGAGTTCCGGCTTCCAGACGGCGGTGCTGCCGGCCGACTTCCAGG
GCGGGCTGCTGGCGTTCCAGTGGTACGCCGAGGGCGGCTCGGGCCTGACGCTGTTCGACAACCTGACCCTCCAGCAGAAC
CGTCCCCCGGTGGCGGAGGACTACTCCGGCGAGGGCCGCGCGGGCGAGACGTTCATCGGCCAGCTGGCCGCCTCGGACCC
CGACGGGCAGGCGCTGGTCTTCCAGCCGGTGGGCGACCTCCCCCAAGGCGTCACCCTCGATCCCGACGGGCGGTTCTACG
TCGAGCCGCTGGAGAGCGACCTGGACCTGCCGGCCGGCCAGAGCCGGGTCGTCACCTTCCAGTACGCGGTGAGCGACGGC
GAGGCGGCCTCCGAGCCCCAGACCGTCACCTTCGAGATCCAGGGGGTGACCGCGCCGGGCAAGGTCATCTGGGGCGACAA
CAAGTCCAATACCCTGACCGGCGATTCCGGTCCCGACACGATCTGGGGCTGGAACGGCGAGGACACCATCGCCGGCGACC
GCGGCGACGACTGGCTGGACGGCGACAACGGCAAGGACAACCTCTCGGGCGGGGCCGGCGCCGACACCCTGTGGGGCGGC
AACGGCAAGGACACCCTCGTGGGCGGCGCCGGCGACGACAAGCTGTTCGGCGGCCTGGGCGAGGATCACTTCATCTTCGA
CCAGGGCTCGGGTCGCGACGTGATCTTCGACTTCCAGTCGGGTCACTGGGAGCACCACAAGCACGGCTGGGGCTGGGGCG
GCTCAGGCAAGCGTTGGGAGCCGGGCGACCTGATCCAGATCTCGCCGGCGACCGTCGGCAGCTTCGACGAGCTGATGCAG
CACGCCGAGCAGAAGTGGTACGGCGTCGAGTTCGACTTCGGCGACGGCTCGTCCCTGACGCTGATGGGCGTGAGCCTGTG
GTCGCTGAACGTGGACGACTTCCTCTTCGCATAG

Upstream 100 bases:

>100_bases
CTTCTTGCTGACCCGTCCTCCGAAATCGGCGTCGCCGCGGCGGCGCAGCGGCCGTTGAGGGCCGGACTGTACCAATTTGG
GGCTAGGGGACCGCTCTGAC

Downstream 100 bases:

>100_bases
CGGCGATCTAGCATCCGGACCGAAGGCTCCGCCGTATCCCTACGGCAGGAGCCAAACCGGGAGATCCACATGCACCGCCT
CGTCGCCGCCGCCGCGCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSIIISFGGVPDGAFNLYEEAGFRFTTATNAPDAFEGGLSIADLGTGEYIFVRNTADTATVEKLDGGAFGVSSVDLDGFR
WTGFTPAGEPIPGSSAVQINFIGYKSDGTTVSWSFSTDASSGFQTAVLPADFQGGLLAFQWYAEGGSGLTLFDNLTLQQN
RPPVAEDYSGEGRAGETFIGQLAASDPDGQALVFQPVGDLPQGVTLDPDGRFYVEPLESDLDLPAGQSRVVTFQYAVSDG
EAASEPQTVTFEIQGVTAPGKVIWGDNKSNTLTGDSGPDTIWGWNGEDTIAGDRGDDWLDGDNGKDNLSGGAGADTLWGG
NGKDTLVGGAGDDKLFGGLGEDHFIFDQGSGRDVIFDFQSGHWEHHKHGWGWGGSGKRWEPGDLIQISPATVGSFDELMQ
HAEQKWYGVEFDFGDGSSLTLMGVSLWSLNVDDFLFA

Sequences:

>Translated_437_residues
MSIIISFGGVPDGAFNLYEEAGFRFTTATNAPDAFEGGLSIADLGTGEYIFVRNTADTATVEKLDGGAFGVSSVDLDGFR
WTGFTPAGEPIPGSSAVQINFIGYKSDGTTVSWSFSTDASSGFQTAVLPADFQGGLLAFQWYAEGGSGLTLFDNLTLQQN
RPPVAEDYSGEGRAGETFIGQLAASDPDGQALVFQPVGDLPQGVTLDPDGRFYVEPLESDLDLPAGQSRVVTFQYAVSDG
EAASEPQTVTFEIQGVTAPGKVIWGDNKSNTLTGDSGPDTIWGWNGEDTIAGDRGDDWLDGDNGKDNLSGGAGADTLWGG
NGKDTLVGGAGDDKLFGGLGEDHFIFDQGSGRDVIFDFQSGHWEHHKHGWGWGGSGKRWEPGDLIQISPATVGSFDELMQ
HAEQKWYGVEFDFGDGSSLTLMGVSLWSLNVDDFLFA
>Mature_436_residues
SIIISFGGVPDGAFNLYEEAGFRFTTATNAPDAFEGGLSIADLGTGEYIFVRNTADTATVEKLDGGAFGVSSVDLDGFRW
TGFTPAGEPIPGSSAVQINFIGYKSDGTTVSWSFSTDASSGFQTAVLPADFQGGLLAFQWYAEGGSGLTLFDNLTLQQNR
PPVAEDYSGEGRAGETFIGQLAASDPDGQALVFQPVGDLPQGVTLDPDGRFYVEPLESDLDLPAGQSRVVTFQYAVSDGE
AASEPQTVTFEIQGVTAPGKVIWGDNKSNTLTGDSGPDTIWGWNGEDTIAGDRGDDWLDGDNGKDNLSGGAGADTLWGGN
GKDTLVGGAGDDKLFGGLGEDHFIFDQGSGRDVIFDFQSGHWEHHKHGWGWGGSGKRWEPGDLIQISPATVGSFDELMQH
AEQKWYGVEFDFGDGSSLTLMGVSLWSLNVDDFLFA

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 7 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 46268; Mature: 46136

Theoretical pI: Translated: 3.79; Mature: 3.79

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIISFGGVPDGAFNLYEEAGFRFTTATNAPDAFEGGLSIADLGTGEYIFVRNTADTAT
CEEEEEECCCCCCHHHHHHHCCCEEEEECCCCCHHHCCEEEEECCCCCEEEEECCCCCCE
VEKLDGGAFGVSSVDLDGFRWTGFTPAGEPIPGSSAVQINFIGYKSDGTTVSWSFSTDAS
EEECCCCEECCCEEECCCEEEECCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCC
SGFQTAVLPADFQGGLLAFQWYAEGGSGLTLFDNLTLQQNRPPVAEDYSGEGRAGETFIG
CCCEEEEECCCCCCCEEEEEEEECCCCCEEEEECEEEECCCCCCCCCCCCCCCCCCCEEE
QLAASDPDGQALVFQPVGDLPQGVTLDPDGRFYVEPLESDLDLPAGQSRVVTFQYAVSDG
EEECCCCCCCEEEEEECCCCCCCCEECCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCC
EAASEPQTVTFEIQGVTAPGKVIWGDNKSNTLTGDSGPDTIWGWNGEDTIAGDRGDDWLD
CCCCCCCEEEEEEEEECCCCEEEECCCCCCEECCCCCCCCEECCCCCCCCCCCCCCCCCC
GDNGKDNLSGGAGADTLWGGNGKDTLVGGAGDDKLFGGLGEDHFIFDQGSGRDVIFDFQS
CCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCHHCCCCCCCCEEEECCCCCEEEEECCC
GHWEHHKHGWGWGGSGKRWEPGDLIQISPATVGSFDELMQHAEQKWYGVEFDFGDGSSLT
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHEEEEEEECCCCCEEE
LMGVSLWSLNVDDFLFA
EEEEEEEEECHHHHCCC
>Mature Secondary Structure 
SIIISFGGVPDGAFNLYEEAGFRFTTATNAPDAFEGGLSIADLGTGEYIFVRNTADTAT
EEEEEECCCCCCHHHHHHHCCCEEEEECCCCCHHHCCEEEEECCCCCEEEEECCCCCCE
VEKLDGGAFGVSSVDLDGFRWTGFTPAGEPIPGSSAVQINFIGYKSDGTTVSWSFSTDAS
EEECCCCEECCCEEECCCEEEECCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCC
SGFQTAVLPADFQGGLLAFQWYAEGGSGLTLFDNLTLQQNRPPVAEDYSGEGRAGETFIG
CCCEEEEECCCCCCCEEEEEEEECCCCCEEEEECEEEECCCCCCCCCCCCCCCCCCCEEE
QLAASDPDGQALVFQPVGDLPQGVTLDPDGRFYVEPLESDLDLPAGQSRVVTFQYAVSDG
EEECCCCCCCEEEEEECCCCCCCCEECCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCC
EAASEPQTVTFEIQGVTAPGKVIWGDNKSNTLTGDSGPDTIWGWNGEDTIAGDRGDDWLD
CCCCCCCEEEEEEEEECCCCEEEECCCCCCEECCCCCCCCEECCCCCCCCCCCCCCCCCC
GDNGKDNLSGGAGADTLWGGNGKDTLVGGAGDDKLFGGLGEDHFIFDQGSGRDVIFDFQS
CCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCHHCCCCCCCCEEEECCCCCEEEEECCC
GHWEHHKHGWGWGGSGKRWEPGDLIQISPATVGSFDELMQHAEQKWYGVEFDFGDGSSLT
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHEEEEEEECCCCCEEE
LMGVSLWSLNVDDFLFA
EEEEEEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8423153 [H]