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The map label for this gene is aapQ [H]

Identifier: 197104925

GI number: 197104925

Start: 1658712

End: 1659878

Strand: Reverse

Name: aapQ [H]

Synonym: PHZ_c1460

Alternate gene names: 197104925

Gene position: 1659878-1658712 (Counterclockwise)

Preceding gene: 197104926

Following gene: 197104924

Centisome position: 41.54

GC content: 74.04

Gene sequence:

>1167_bases
ATGACGGCGCATTCCTCCGCCCCCCGACGCCCGCGCCGGGTCCCGGCCTCCCCCGCCGCCATCCTGGCGCAGGCCGGCGC
GGTCGCCCTGGTGGCGGCCGCGCTCCTGCTGGTGGCGGTCAGCACGGCGGCCAACCTGCAGGCCCGGGGCCTGCCGCTCG
GATTGGAGTTCCTGGGGGATCGCGCCGGCTTCAAGATCGCCGACACGGTGCTGCCCTTCGGCCCGGAAGACACCTACCTG
CAGGCGATCGGCGTCGCCGTCGCCAACACCGTGTTCCTGTCCGCCCTGGTCTGCGTCGCCGCCACCGTCATCGGAACGGC
GCTGGGCGTCGCCCGGCTGAGCGCCAACCCCCTCGTCGCCGGGCTGGCGGCGGTGTGGGTCGAGGCGATGCGCAACACCC
CGCCGGTCCTGCTGCTCATCTTCCTCTACGCCTACTGGGGGCAGGTGATGCCGGTCGGCGGGGCCCGGGAACTCTTGCCC
GGCCTGCTGGTCTCGATCCGCGGGGTGGCCGCCCCCCGCCTCGTGGCCGAGTGGCCGCTCCTCGGCCTCGCCGGCGCGCT
CGCCGCCGGGGCCGCCGTCTATGGCGCAGCCGCCCTCGCCGGCCGCGCCGCCGCCCGCCGCGGCCGGCCACGCCCCCACC
GGGCGGCTGCGGCGGGCGTGATCGTCCTGGGGGCGCTGGCGGCGTTCGCCATTCACCCGCCGCTGCGTCTGGAAACGCCG
GCGGCCACGGGCGACGACCTGGCCGGCGGGGCGCGCCTGACGCCGGAGTTCGCCACGGTGTTCGCCGGCCTCACCGTCTA
CACCGCGGCCTTCATCGCCGAGATCGTGCGCTCGGGCGTCCAGTCGGTGCCGCGCGGCCAGTGGGAGGCCGCCCGCGCGC
TCGGGCTCAAGGAGCGGCAGATCCTGCGGCTCGTGGCCTTCCCGCAGATGCTGCGGGTGATCGTCCCGCCGATGACCAGC
CAGTACATCAACACGGTCAAGAACAGCACGCTCGCCATCGCCATCGGCTATTCGGAGTTCATGACCGTGATGGGGACGGT
CATCAACCGGACCAACCACCCGATCGAGGGCACCCTGATCATTCTCCTCGTCTACCTGGCGCTGAACCTGGCGCTGGCGG
CCCTGCTCGACCTCTACAACCGGCGCGTCCAGCTGGAGGGCCGCTGA

Upstream 100 bases:

>100_bases
AACCTCGGCGCCCGCACCCGCATCAAGGCCGACCGCCGCCTCAACCGGCCGTACAAGGACGGCGGCCTGCTGTTCCCCTA
TCCCTGGGACGTGTGAGCCG

Downstream 100 bases:

>100_bases
GATGACCTCCGTCGCGACCCCGGGCCCGCCGCGGGCCGCCCGCGGCCCCGCCGTCCTGGCCGCGAGGCTGTTCGGCTCGC
CGCTCAACGTCGTCCTGACC

Product: ABC-type amino acid transport system, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTAHSSAPRRPRRVPASPAAILAQAGAVALVAAALLLVAVSTAANLQARGLPLGLEFLGDRAGFKIADTVLPFGPEDTYL
QAIGVAVANTVFLSALVCVAATVIGTALGVARLSANPLVAGLAAVWVEAMRNTPPVLLLIFLYAYWGQVMPVGGARELLP
GLLVSIRGVAAPRLVAEWPLLGLAGALAAGAAVYGAAALAGRAAARRGRPRPHRAAAAGVIVLGALAAFAIHPPLRLETP
AATGDDLAGGARLTPEFATVFAGLTVYTAAFIAEIVRSGVQSVPRGQWEAARALGLKERQILRLVAFPQMLRVIVPPMTS
QYINTVKNSTLAIAIGYSEFMTVMGTVINRTNHPIEGTLIILLVYLALNLALAALLDLYNRRVQLEGR

Sequences:

>Translated_388_residues
MTAHSSAPRRPRRVPASPAAILAQAGAVALVAAALLLVAVSTAANLQARGLPLGLEFLGDRAGFKIADTVLPFGPEDTYL
QAIGVAVANTVFLSALVCVAATVIGTALGVARLSANPLVAGLAAVWVEAMRNTPPVLLLIFLYAYWGQVMPVGGARELLP
GLLVSIRGVAAPRLVAEWPLLGLAGALAAGAAVYGAAALAGRAAARRGRPRPHRAAAAGVIVLGALAAFAIHPPLRLETP
AATGDDLAGGARLTPEFATVFAGLTVYTAAFIAEIVRSGVQSVPRGQWEAARALGLKERQILRLVAFPQMLRVIVPPMTS
QYINTVKNSTLAIAIGYSEFMTVMGTVINRTNHPIEGTLIILLVYLALNLALAALLDLYNRRVQLEGR
>Mature_387_residues
TAHSSAPRRPRRVPASPAAILAQAGAVALVAAALLLVAVSTAANLQARGLPLGLEFLGDRAGFKIADTVLPFGPEDTYLQ
AIGVAVANTVFLSALVCVAATVIGTALGVARLSANPLVAGLAAVWVEAMRNTPPVLLLIFLYAYWGQVMPVGGARELLPG
LLVSIRGVAAPRLVAEWPLLGLAGALAAGAAVYGAAALAGRAAARRGRPRPHRAAAAGVIVLGALAAFAIHPPLRLETPA
ATGDDLAGGARLTPEFATVFAGLTVYTAAFIAEIVRSGVQSVPRGQWEAARALGLKERQILRLVAFPQMLRVIVPPMTSQ
YINTVKNSTLAIAIGYSEFMTVMGTVINRTNHPIEGTLIILLVYLALNLALAALLDLYNRRVQLEGR

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=363, Percent_Identity=38.5674931129477, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1786874, Length=141, Percent_Identity=39.0070921985816, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786873, Length=119, Percent_Identity=31.0924369747899, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788226, Length=126, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787030, Length=134, Percent_Identity=31.3432835820896, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082239, Length=125, Percent_Identity=28, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787087, Length=107, Percent_Identity=28.9719626168224, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40318; Mature: 40187

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHSSAPRRPRRVPASPAAILAQAGAVALVAAALLLVAVSTAANLQARGLPLGLEFLGD
CCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHCC
RAGFKIADTVLPFGPEDTYLQAIGVAVANTVFLSALVCVAATVIGTALGVARLSANPLVA
CCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GLAAVWVEAMRNTPPVLLLIFLYAYWGQVMPVGGARELLPGLLVSIRGVAAPRLVAEWPL
HHHHHHHHHHHCCCHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCH
LGLAGALAAGAAVYGAAALAGRAAARRGRPRPHRAAAAGVIVLGALAAFAIHPPLRLETP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCC
AATGDDLAGGARLTPEFATVFAGLTVYTAAFIAEIVRSGVQSVPRGQWEAARALGLKERQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHH
ILRLVAFPQMLRVIVPPMTSQYINTVKNSTLAIAIGYSEFMTVMGTVINRTNHPIEGTLI
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCCCHHHHH
ILLVYLALNLALAALLDLYNRRVQLEGR
HHHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure 
TAHSSAPRRPRRVPASPAAILAQAGAVALVAAALLLVAVSTAANLQARGLPLGLEFLGD
CCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHCC
RAGFKIADTVLPFGPEDTYLQAIGVAVANTVFLSALVCVAATVIGTALGVARLSANPLVA
CCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GLAAVWVEAMRNTPPVLLLIFLYAYWGQVMPVGGARELLPGLLVSIRGVAAPRLVAEWPL
HHHHHHHHHHHCCCHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCH
LGLAGALAAGAAVYGAAALAGRAAARRGRPRPHRAAAAGVIVLGALAAFAIHPPLRLETP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCC
AATGDDLAGGARLTPEFATVFAGLTVYTAAFIAEIVRSGVQSVPRGQWEAARALGLKERQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHH
ILRLVAFPQMLRVIVPPMTSQYINTVKNSTLAIAIGYSEFMTVMGTVINRTNHPIEGTLI
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCCCHHHHH
ILLVYLALNLALAALLDLYNRRVQLEGR
HHHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]