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The map label for this gene is dinP [H]

Identifier: 197104770

GI number: 197104770

Start: 1483004

End: 1484290

Strand: Reverse

Name: dinP [H]

Synonym: PHZ_c1304

Alternate gene names: 197104770

Gene position: 1484290-1483004 (Counterclockwise)

Preceding gene: 197104771

Following gene: 197104769

Centisome position: 37.14

GC content: 72.03

Gene sequence:

>1287_bases
ATGGCTGTGGCCGCGATGAAGGCCCTCTGCCGCGATTGCCTCTGGACGGGGGAGGACCAGCCGCGCCGCTGTCCGGCCTG
CGGCTCGCCGCGGATCGTGGCCCACGAGGAGCTGGGCGCGCTGTCCATCGCCCACATGGACTGCGACGCCTTCTACGCCA
GCGTCGAGAAGCGCGACCGGCCCGAGCTGCGGGACGTGCCGGTCATCGTCGGCGGCGGGAAACGCGGCGTCGTCACCACC
TGCTGCTACATCGCCCGGATCAAGGGCGTGCGCTCGGCCATGCCGATGTTCAAGGCGCTGAAGGCCTGTCCGGAGGCCGT
GGTGATCAAGCCCGACTTCACCAAGTACCGGGCCGAGAGCAGGCGCATCCTGGGCCTGGCGGGCGAGCTCACCCCGCTGA
TCCAGAACCTGTCGCTGGACGAGGCGTGGATGGACCTGTCCGGCACCGAGCGCCTGCACGGCGCCCCGCCGGCCGTGACG
CTGGCCAGGCTGCAGGCGCGCATCGAGGCCGAGACCGGCCTGACCGTCTCGATCGGCCTCGCCCCCAACAAGTTCCTGGC
GAAGATCGCCTCCGACCTCGACAAGCCCCGCGGCTTCTCGGTGATCGGGGGGAAGTCGGCGCAGGCCTTCCTCGCGCCGA
AGCCGGTCTCGATCCTGCCGGGCGTGGGCCCCGCCATGGCCGCCTCGCTCGAGAAGGCCGGCTACCGCACGGTCGGCGAC
CTGGCCCGGGCCGACGCGAAGGCCCTGGCCGAGCGCTGGGGCGCCCATGGCCTGCGCCTTTCGCAGCTGGCCCACGGCCA
GGATGCGCGCACCGTCAATCCGAACGAGGCGCGCAAGGGGATCAGCGCCGAGACCACCTTCAACGAGGACCTATCGGGGC
TCGCCGACCTCGAGGACCAGCTCGCGCCGCTGTGCGACAAGGTCGCGCGCAAGGCCCGGGCCGACGGCGTGGCGGGGCGC
GTGGTGACGCTGAAGCTGCGAACCACCGACTTCCGGATCGTCACCCGCCGGCGGACCCTGCCCGTCGCCACCCAGACCGC
CAAGACGCTGTTCGCGGTCGGCCGGGAGCTGCTGGCCAAGGAAGCGACGGGGCGGCCCTGGCGGCTGATCGGCATCGGCG
TCGCCGACCTGGTGGACGCCGAGACCGCCACCGCCGACTTCTTCGCCGAGGCCGAGCGCCGGGCCCTGGCCGGCGAGAAG
ACCCTGGACGTGCTGCGCGCCAGGTTCGGCAAGGATGCGGTGACTTCGGGCAGGATGCTCAAGGCCAAGGCGCTCAACGA
AGAGTGA

Upstream 100 bases:

>100_bases
GGCTGCCGGCCGCCATCGCCCCGCACGTGTTCTCGGACGTGTTCGCGACGCCGGTGCGCCGGGCCGCGCACGGGGACTCC
TCGGGCGTGCGCGGCGCTGC

Downstream 100 bases:

>100_bases
TCGCAGGCCCCAACCCCGGGTGGCGGAGCCGCTCCGGTCTGGGGCCGTTCACCCCCGGCGTGACGATTCGACCCTTCCAA
ATGACCGCATCTTCCATATC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MAVAAMKALCRDCLWTGEDQPRRCPACGSPRIVAHEELGALSIAHMDCDAFYASVEKRDRPELRDVPVIVGGGKRGVVTT
CCYIARIKGVRSAMPMFKALKACPEAVVIKPDFTKYRAESRRILGLAGELTPLIQNLSLDEAWMDLSGTERLHGAPPAVT
LARLQARIEAETGLTVSIGLAPNKFLAKIASDLDKPRGFSVIGGKSAQAFLAPKPVSILPGVGPAMAASLEKAGYRTVGD
LARADAKALAERWGAHGLRLSQLAHGQDARTVNPNEARKGISAETTFNEDLSGLADLEDQLAPLCDKVARKARADGVAGR
VVTLKLRTTDFRIVTRRRTLPVATQTAKTLFAVGRELLAKEATGRPWRLIGIGVADLVDAETATADFFAEAERRALAGEK
TLDVLRARFGKDAVTSGRMLKAKALNEE

Sequences:

>Translated_428_residues
MAVAAMKALCRDCLWTGEDQPRRCPACGSPRIVAHEELGALSIAHMDCDAFYASVEKRDRPELRDVPVIVGGGKRGVVTT
CCYIARIKGVRSAMPMFKALKACPEAVVIKPDFTKYRAESRRILGLAGELTPLIQNLSLDEAWMDLSGTERLHGAPPAVT
LARLQARIEAETGLTVSIGLAPNKFLAKIASDLDKPRGFSVIGGKSAQAFLAPKPVSILPGVGPAMAASLEKAGYRTVGD
LARADAKALAERWGAHGLRLSQLAHGQDARTVNPNEARKGISAETTFNEDLSGLADLEDQLAPLCDKVARKARADGVAGR
VVTLKLRTTDFRIVTRRRTLPVATQTAKTLFAVGRELLAKEATGRPWRLIGIGVADLVDAETATADFFAEAERRALAGEK
TLDVLRARFGKDAVTSGRMLKAKALNEE
>Mature_427_residues
AVAAMKALCRDCLWTGEDQPRRCPACGSPRIVAHEELGALSIAHMDCDAFYASVEKRDRPELRDVPVIVGGGKRGVVTTC
CYIARIKGVRSAMPMFKALKACPEAVVIKPDFTKYRAESRRILGLAGELTPLIQNLSLDEAWMDLSGTERLHGAPPAVTL
ARLQARIEAETGLTVSIGLAPNKFLAKIASDLDKPRGFSVIGGKSAQAFLAPKPVSILPGVGPAMAASLEKAGYRTVGDL
ARADAKALAERWGAHGLRLSQLAHGQDARTVNPNEARKGISAETTFNEDLSGLADLEDQLAPLCDKVARKARADGVAGRV
VTLKLRTTDFRIVTRRRTLPVATQTAKTLFAVGRELLAKEATGRPWRLIGIGVADLVDAETATADFFAEAERRALAGEKT
LDVLRARFGKDAVTSGRMLKAKALNEE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=310, Percent_Identity=29.0322580645161, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI84043967, Length=356, Percent_Identity=25.2808988764045, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI7706681, Length=357, Percent_Identity=25.2100840336134, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI7705344, Length=106, Percent_Identity=43.3962264150943, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1786425, Length=340, Percent_Identity=37.9411764705882, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1787432, Length=390, Percent_Identity=23.8461538461538, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193205700, Length=402, Percent_Identity=30.5970149253731, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193205702, Length=354, Percent_Identity=28.5310734463277, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17537959, Length=196, Percent_Identity=27.0408163265306, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324921, Length=313, Percent_Identity=24.9201277955272, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19923006, Length=364, Percent_Identity=26.0989010989011, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI21355641, Length=336, Percent_Identity=27.6785714285714, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24644984, Length=336, Percent_Identity=27.6785714285714, Blast_Score=112, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45926; Mature: 45794

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAAMKALCRDCLWTGEDQPRRCPACGSPRIVAHEELGALSIAHMDCDAFYASVEKRDR
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHCCCCEEEEECCHHHHHHHHHHCCC
PELRDVPVIVGGGKRGVVTTCCYIARIKGVRSAMPMFKALKACPEAVVIKPDFTKYRAES
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHC
RRILGLAGELTPLIQNLSLDEAWMDLSGTERLHGAPPAVTLARLQARIEAETGLTVSIGL
CCEEEHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
APNKFLAKIASDLDKPRGFSVIGGKSAQAFLAPKPVSILPGVGPAMAASLEKAGYRTVGD
CCHHHHHHHHHHCCCCCCCEEECCCCCCEEECCCCCHHCCCCCHHHHHHHHHCCCHHHHH
LARADAKALAERWGAHGLRLSQLAHGQDARTVNPNEARKGISAETTFNEDLSGLADLEDQ
HHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHH
LAPLCDKVARKARADGVAGRVVTLKLRTTDFRIVTRRRTLPVATQTAKTLFAVGRELLAK
HHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
EATGRPWRLIGIGVADLVDAETATADFFAEAERRALAGEKTLDVLRARFGKDAVTSGRML
HCCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCCEE
KAKALNEE
EECCCCCC
>Mature Secondary Structure 
AVAAMKALCRDCLWTGEDQPRRCPACGSPRIVAHEELGALSIAHMDCDAFYASVEKRDR
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHCCCCEEEEECCHHHHHHHHHHCCC
PELRDVPVIVGGGKRGVVTTCCYIARIKGVRSAMPMFKALKACPEAVVIKPDFTKYRAES
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHC
RRILGLAGELTPLIQNLSLDEAWMDLSGTERLHGAPPAVTLARLQARIEAETGLTVSIGL
CCEEEHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
APNKFLAKIASDLDKPRGFSVIGGKSAQAFLAPKPVSILPGVGPAMAASLEKAGYRTVGD
CCHHHHHHHHHHCCCCCCCEEECCCCCCEEECCCCCHHCCCCCHHHHHHHHHCCCHHHHH
LARADAKALAERWGAHGLRLSQLAHGQDARTVNPNEARKGISAETTFNEDLSGLADLEDQ
HHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHH
LAPLCDKVARKARADGVAGRVVTLKLRTTDFRIVTRRRTLPVATQTAKTLFAVGRELLAK
HHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
EATGRPWRLIGIGVADLVDAETATADFFAEAERRALAGEKTLDVLRARFGKDAVTSGRML
HCCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCCEE
KAKALNEE
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]