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The map label for this gene is clpA [C]

Identifier: 197104768

GI number: 197104768

Start: 1480207

End: 1482522

Strand: Reverse

Name: clpA [C]

Synonym: PHZ_c1302

Alternate gene names: 197104768

Gene position: 1482522-1480207 (Counterclockwise)

Preceding gene: 197104769

Following gene: 197104762

Centisome position: 37.1

GC content: 67.49

Gene sequence:

>2316_bases
TTGCCTTCATTTTCGCGCCAGCTCGAAGAGTCCCTGCACCGCGCGGTCGCCTACGCCAACCAGCGTAAGCATGAATACGC
CACCCTGGAGCACCTGCTGCTCTCTCTCGTGGACGACGAGGACGCCGCCGGCGTCATGCGCGCCTGCGACGTGGACCTGG
GCGCGCTGCGCACCACCCTGACCAACTACGTCGACAACGAGCTCCGCTCGCTGGTCGTGGACGACGGCGAGGACGCCAAG
CCCACCGCCGGCTTCCAGCGCGTGATCCAGCGCGCGGTGATCCACGTCCAGTCCTCGGGCCGCGAGGAGGTGACCGGCGC
CAACGTGCTGGTGGCCATCTTCTCCGAGCGCGAGAGCCACGCCGCCTACTTCCTGCAGGAGCAGGACATGACGCGGTACG
ACGCGGTGAACTACATCGCCCACGGCATCGCCAAGAAGGCCGGCGCCACCGAGGCCAAGCCGGTGAAGGGCGCCGAGGAC
GACGAGAAGCCCCAGGTCAAGACCGGCGGCGAGGCGCTCGAGGCCTACTGCATCAACCTCAACGAGAAGGCCAAGCAGGG
GAAGGTCGACCCGCTGATCGGCCGGATGGCCGAGGTCGAGCGCTGCATCCAGATCCTGTGCCGGCGCACCAAGAACAACC
CGCTGCTGGTGGGCGACCCCGGCGTCGGCAAGACCGCCATCGCCGAGGGGCTGGCGCGCAAGATCGTCAACAAGCAGGTC
CCCGAGGTCCTGGCGAACGCGACCATCTTCTCGCTCGACATGGGCGCGCTGCTGGCCGGCACGCGCTACCGCGGCGACTT
CGAGGAACGCGTGAAGCAGGTCGTCAAGGAGCTGGAGAACCACCCCGACGCGGTCCTGTTCATCGACGAGATCCACACGG
TGATCGGCGCCGGCGCCACCTCGGGCGGGGCCATGGACGCCTCGAACCTGCTGAAGCCGGCGCTGGCCTCGGGCACGCTG
CGCTGCATGGGCTCGACGACTTACAAGGAGTTCCGCCAGCACTTCGAGAAGGACCGGGCCCTCGTCCGGCGCTTCCAGAA
GATCGACGTGAACGAGCCGACGATCGACGACACGATCAAGATCCTGAAGGGGCTGAAGTCCTACTACGAGGAGTTCCACA
AGCTCCGGTACACGAACGACGCCATCAAGGCGGCGGTGGAGCTGTCGGCGAAGTACATCACCGACCGCAAGCTGCCCGAC
AAGGCGATCGACATCATCGACGAGGCCGGCGCCTCGCAGATGCTGCTCCCCGAGGGCAGGCGGAAGAAGACCCTGGGCGT
GAAGGAGGTCGAGGCGGTCGTCGCCAAGATCGCCCGGATCCCGCCCAAGTCGGTGTCGAAGTCCGACACCGAAGCGCTGA
AGCAGCTGGAAGGCGACCTGAAGCGCGCGGTCTACGGCCAGGACGAGGCCATCGAGCAGCTGTCCGCCGCCATGAAGATG
GCCCGGGCCGGCCTGCGCGACGCGAACAAGCCGATCGGCTGCTACCTGTTCACGGGCCCGACCGGCACCGGCAAGACCGA
GACCGCCCGCCAGCTGGCCGGCACCCTCGGCATCGAGCTGCTGCGGTTCGACATGTCGGAGTACATGGAGCGCCACACGG
TCAGCCGCCTGATCGGCGCGCCTCCCGGCTACGTCGGCTTCGACCAAGGGGGTCTGCTGACCGACGCGGTCGACCAGCAT
CCGCACGCCGTGGTCCTGCTGGACGAGATCGAGAAGGCTCACCCGGACGTCTACAACATCCTCCTGCAGGTCATGGACCA
CGGTCAGCTGACCGACTCCAACGGCAAGAAGATCGACTTCCGCAACGTGGTCCTGATCATGACCACCAACGCCGGCGCCG
CCGACGCCCAGCGCAACGCCATCGGCTTCGGCCGCGGCAAGCAGGACGACGAGGTGGAAGAGGCGCTGAAGCGGCAGTTC
ACGCCCGAGTTCCGCAACCGCCTCGACGCGATCGTGCACTTCCACGCGCTGACGCCCGAGATCATCCGGCAGGTGGTGCT
CAAGTTCGTCATGCAGCTGGAGGCCCAGCTGGCGGACCGGCACGTCACCATCGAGACGGACGACGAGGCCGCCGACTGGC
TGGCCAAGAACGGCTTCGACGAGCTCTACGGCGCCCGGCCGCTGGCCCGGGTCATCCAGGAGAACATCAAGAAGCCCCTG
GCCGACGAGATCCTGTTCGGCCGGCTCACCAAGGGCGGCCACGTCAAGGTGGTGCTCAAGGACGGCAAGCTGGCGTTCGA
GATCGAGGGCCAGACCCGCGAACCCGGCGCCCCGGTGGTCGAGAAGCCCGCCGAGGAGACCGAGCCGGTCGACTGA

Upstream 100 bases:

>100_bases
CACATACGAAGTGGCGGAAACAAAAGTGGCCCAGGTCGTTGATACGGCGCGGCGGCACCAACATCCGCTGCAATGCACCA
TGGAAAAGGATTAAGGCCCT

Downstream 100 bases:

>100_bases
GCGGCGGTCTACGAGGAAAAGCGAAGGGCCCCGGAGAGCGATCGCAGAGAGCGATCTCCGGGGCCTTGTCGCGTCAGCTG
ATCTTCGCCGAGATCTGCTC

Product: ATP-dependent Clp protease, ATP-binding subunit ClpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 771; Mature: 770

Protein sequence:

>771_residues
MPSFSRQLEESLHRAVAYANQRKHEYATLEHLLLSLVDDEDAAGVMRACDVDLGALRTTLTNYVDNELRSLVVDDGEDAK
PTAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFSERESHAAYFLQEQDMTRYDAVNYIAHGIAKKAGATEAKPVKGAED
DEKPQVKTGGEALEAYCINLNEKAKQGKVDPLIGRMAEVERCIQILCRRTKNNPLLVGDPGVGKTAIAEGLARKIVNKQV
PEVLANATIFSLDMGALLAGTRYRGDFEERVKQVVKELENHPDAVLFIDEIHTVIGAGATSGGAMDASNLLKPALASGTL
RCMGSTTYKEFRQHFEKDRALVRRFQKIDVNEPTIDDTIKILKGLKSYYEEFHKLRYTNDAIKAAVELSAKYITDRKLPD
KAIDIIDEAGASQMLLPEGRRKKTLGVKEVEAVVAKIARIPPKSVSKSDTEALKQLEGDLKRAVYGQDEAIEQLSAAMKM
ARAGLRDANKPIGCYLFTGPTGTGKTETARQLAGTLGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVDQH
PHAVVLLDEIEKAHPDVYNILLQVMDHGQLTDSNGKKIDFRNVVLIMTTNAGAADAQRNAIGFGRGKQDDEVEEALKRQF
TPEFRNRLDAIVHFHALTPEIIRQVVLKFVMQLEAQLADRHVTIETDDEAADWLAKNGFDELYGARPLARVIQENIKKPL
ADEILFGRLTKGGHVKVVLKDGKLAFEIEGQTREPGAPVVEKPAEETEPVD

Sequences:

>Translated_771_residues
MPSFSRQLEESLHRAVAYANQRKHEYATLEHLLLSLVDDEDAAGVMRACDVDLGALRTTLTNYVDNELRSLVVDDGEDAK
PTAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFSERESHAAYFLQEQDMTRYDAVNYIAHGIAKKAGATEAKPVKGAED
DEKPQVKTGGEALEAYCINLNEKAKQGKVDPLIGRMAEVERCIQILCRRTKNNPLLVGDPGVGKTAIAEGLARKIVNKQV
PEVLANATIFSLDMGALLAGTRYRGDFEERVKQVVKELENHPDAVLFIDEIHTVIGAGATSGGAMDASNLLKPALASGTL
RCMGSTTYKEFRQHFEKDRALVRRFQKIDVNEPTIDDTIKILKGLKSYYEEFHKLRYTNDAIKAAVELSAKYITDRKLPD
KAIDIIDEAGASQMLLPEGRRKKTLGVKEVEAVVAKIARIPPKSVSKSDTEALKQLEGDLKRAVYGQDEAIEQLSAAMKM
ARAGLRDANKPIGCYLFTGPTGTGKTETARQLAGTLGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVDQH
PHAVVLLDEIEKAHPDVYNILLQVMDHGQLTDSNGKKIDFRNVVLIMTTNAGAADAQRNAIGFGRGKQDDEVEEALKRQF
TPEFRNRLDAIVHFHALTPEIIRQVVLKFVMQLEAQLADRHVTIETDDEAADWLAKNGFDELYGARPLARVIQENIKKPL
ADEILFGRLTKGGHVKVVLKDGKLAFEIEGQTREPGAPVVEKPAEETEPVD
>Mature_770_residues
PSFSRQLEESLHRAVAYANQRKHEYATLEHLLLSLVDDEDAAGVMRACDVDLGALRTTLTNYVDNELRSLVVDDGEDAKP
TAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFSERESHAAYFLQEQDMTRYDAVNYIAHGIAKKAGATEAKPVKGAEDD
EKPQVKTGGEALEAYCINLNEKAKQGKVDPLIGRMAEVERCIQILCRRTKNNPLLVGDPGVGKTAIAEGLARKIVNKQVP
EVLANATIFSLDMGALLAGTRYRGDFEERVKQVVKELENHPDAVLFIDEIHTVIGAGATSGGAMDASNLLKPALASGTLR
CMGSTTYKEFRQHFEKDRALVRRFQKIDVNEPTIDDTIKILKGLKSYYEEFHKLRYTNDAIKAAVELSAKYITDRKLPDK
AIDIIDEAGASQMLLPEGRRKKTLGVKEVEAVVAKIARIPPKSVSKSDTEALKQLEGDLKRAVYGQDEAIEQLSAAMKMA
RAGLRDANKPIGCYLFTGPTGTGKTETARQLAGTLGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVDQHP
HAVVLLDEIEKAHPDVYNILLQVMDHGQLTDSNGKKIDFRNVVLIMTTNAGAADAQRNAIGFGRGKQDDEVEEALKRQFT
PEFRNRLDAIVHFHALTPEIIRQVVLKFVMQLEAQLADRHVTIETDDEAADWLAKNGFDELYGARPLARVIQENIKKPLA
DEILFGRLTKGGHVKVVLKDGKLAFEIEGQTREPGAPVVEKPAEETEPVD

Specific function: ATP-Dependent Specificity Component Of The Clpp Protease. It Directs The Protease To Specific Substrates. The Primary Function Of The Clpa-Clpp Complex Appears To Be The Degradation Of Unfolded Or Abnormal Proteins. [C]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=319, Percent_Identity=34.1692789968652, Blast_Score=168, Evalue=2e-41,
Organism=Escherichia coli, GI1787109, Length=737, Percent_Identity=59.7014925373134, Blast_Score=900, Evalue=0.0,
Organism=Escherichia coli, GI1788943, Length=391, Percent_Identity=44.5012787723785, Blast_Score=303, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6320464, Length=324, Percent_Identity=47.8395061728395, Blast_Score=296, Evalue=9e-81,
Organism=Saccharomyces cerevisiae, GI6323002, Length=242, Percent_Identity=48.7603305785124, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR013461
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 85027; Mature: 84896

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSFSRQLEESLHRAVAYANQRKHEYATLEHLLLSLVDDEDAAGVMRACDVDLGALRTTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHH
TNYVDNELRSLVVDDGEDAKPTAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFSERESH
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCH
AAYFLQEQDMTRYDAVNYIAHGIAKKAGATEAKPVKGAEDDEKPQVKTGGEALEAYCINL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
NEKAKQGKVDPLIGRMAEVERCIQILCRRTKNNPLLVGDPGVGKTAIAEGLARKIVNKQV
CCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
PEVLANATIFSLDMGALLAGTRYRGDFEERVKQVVKELENHPDAVLFIDEIHTVIGAGAT
HHHHHCCHHEEECHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCC
SGGAMDASNLLKPALASGTLRCMGSTTYKEFRQHFEKDRALVRRFQKIDVNEPTIDDTIK
CCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ILKGLKSYYEEFHKLRYTNDAIKAAVELSAKYITDRKLPDKAIDIIDEAGASQMLLPEGR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCC
RKKTLGVKEVEAVVAKIARIPPKSVSKSDTEALKQLEGDLKRAVYGQDEAIEQLSAAMKM
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ARAGLRDANKPIGCYLFTGPTGTGKTETARQLAGTLGIELLRFDMSEYMERHTVSRLIGA
HHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPGYVGFDQGGLLTDAVDQHPHAVVLLDEIEKAHPDVYNILLQVMDHGQLTDSNGKKIDF
CCCCCCCCCCCCCHHHHCCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEE
RNVVLIMTTNAGAADAQRNAIGFGRGKQDDEVEEALKRQFTPEFRNRLDAIVHFHALTPE
CCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHH
IIRQVVLKFVMQLEAQLADRHVTIETDDEAADWLAKNGFDELYGARPLARVIQENIKKPL
HHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCH
ADEILFGRLTKGGHVKVVLKDGKLAFEIEGQTREPGAPVVEKPAEETEPVD
HHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSFSRQLEESLHRAVAYANQRKHEYATLEHLLLSLVDDEDAAGVMRACDVDLGALRTTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHH
TNYVDNELRSLVVDDGEDAKPTAGFQRVIQRAVIHVQSSGREEVTGANVLVAIFSERESH
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCH
AAYFLQEQDMTRYDAVNYIAHGIAKKAGATEAKPVKGAEDDEKPQVKTGGEALEAYCINL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
NEKAKQGKVDPLIGRMAEVERCIQILCRRTKNNPLLVGDPGVGKTAIAEGLARKIVNKQV
CCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
PEVLANATIFSLDMGALLAGTRYRGDFEERVKQVVKELENHPDAVLFIDEIHTVIGAGAT
HHHHHCCHHEEECHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCC
SGGAMDASNLLKPALASGTLRCMGSTTYKEFRQHFEKDRALVRRFQKIDVNEPTIDDTIK
CCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ILKGLKSYYEEFHKLRYTNDAIKAAVELSAKYITDRKLPDKAIDIIDEAGASQMLLPEGR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCC
RKKTLGVKEVEAVVAKIARIPPKSVSKSDTEALKQLEGDLKRAVYGQDEAIEQLSAAMKM
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ARAGLRDANKPIGCYLFTGPTGTGKTETARQLAGTLGIELLRFDMSEYMERHTVSRLIGA
HHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPGYVGFDQGGLLTDAVDQHPHAVVLLDEIEKAHPDVYNILLQVMDHGQLTDSNGKKIDF
CCCCCCCCCCCCCHHHHCCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEE
RNVVLIMTTNAGAADAQRNAIGFGRGKQDDEVEEALKRQFTPEFRNRLDAIVHFHALTPE
CCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHH
IIRQVVLKFVMQLEAQLADRHVTIETDDEAADWLAKNGFDELYGARPLARVIQENIKKPL
HHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCH
ADEILFGRLTKGGHVKVVLKDGKLAFEIEGQTREPGAPVVEKPAEETEPVD
HHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6209404 [H]