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The map label for this gene is degQ [C]

Identifier: 197104727

GI number: 197104727

Start: 1437619

End: 1439013

Strand: Direct

Name: degQ [C]

Synonym: PHZ_c1261

Alternate gene names: 197104727

Gene position: 1437619-1439013 (Clockwise)

Preceding gene: 197104726

Following gene: 197104728

Centisome position: 35.97

GC content: 74.91

Gene sequence:

>1395_bases
ATGCGCGCCACCCGCGTCCTGATCCCCGCCTGCGCCCTGATGATGGCCGCGGCCGCCCCCCTCGGCGTCGCGGCGCAGGT
CCAGTCCAACCGCGTCCCGCCGACGAGCGCGGTCGCCATGAAGAGCAGCTTCGCCCCCGTGGTGAAGCGGGCGGCGCCGG
CCGTGGTCAACATCTCGGCCCGGCGGCTGGTGCGCCAGCAGACCGACCCCTTCTGGCAGCTGTTCGGCCTGGGCGCGCCG
CGCGCCCGGATCGCCAATTCGCTGGGCTCGGGCGTCATCGTCCGGCCCGACGGGATCATCGTGACCAACAACCACGTCGT
CGAGAACGGCCAGGAGATCACCGTCGCCCTGGCCGACCGGCGCGAGTTCCCCGCCCGCATCCTGCTGGCCGACCCCCGCA
CCGACCTCGCCGTGCTGAAGATCGACGTGCCGGCCGGCGAGCGCCTGCCGGTGCTGCCCATCGACGATTCGGGGGACACC
GAGGTCGGCGACCTGGTCCTGGCCATCGGCGATCCCTTCGGCGTCGGCCAGACGGTCACCAACGGCATTGTCTCGGCGAT
CAACCGCACGCCCGACGACGACGGCGCCTCGGCCTACATCCAGACCGACGCGGCCATCAATCCGGGCAACTCGGGCGGCG
CCCTGGTCGACATGGACGGCGACCTGATCGGCGTGAACAGCTTCATCCTGTCCCGCTCGGGCACCTCTTCGGGCGTCGGC
TTCGCCGTGCCGGCGGCCGTGGTGCGCCGGGTGGTAGAGACGGCGGCGGGCGGCGGCCGCGCGGTCGTGCGGCCCTGGCT
GGGCGCGCGGACCCAGACGGTCACCGCCGAGATCGCCCGCACGCTCGGCATGGCCCGCCCCCAGGGCGCGCTGGTCGCCG
ACGTCTGGCCGGGCGGGGCGGCGTTCCGGGCGGGGCTGCGCCAGGGCGACGTCGTCACCGAGGTGGACGGCCGGCCGGTG
ACCGACGCCGCCAGCCTGAACTACGCCTTCGCGACCCGCCGGCCCGGCGACACGGTCCGGCTCACCGTGCGCCGCGACGC
CGGCCGCGAGCAGACGCTGGAGGTGCGGGCCGAGGCGCCGCCCGCCTCGCCGGCGCGCGACGAGCGCACCATCGAGGGCC
AGAACCCGCTGAGCGGCGCGACGGTCGTGAACCTGTCCCCCGCCGTCGCCGACGAGCTGGGCCTGGATCCGTTCGCTGGC
CGCGGCGTGCTCATCTCGCGCCTGGACCGCGGCTTCGCCGTGGGCGCAGGGTTCCGGCCCGGCGACATCATCCGTGGCGT
CAACGGCCGCCGGGTGGAGAGCGTCCGCGAGCTGACGGCGGCGCTGGAGACGCCTTCGCGCGGATGGCAGATCGCCTTCG
AGCGAGGCGGCCAGCTGATCACCGCCCGGTTCTGA

Upstream 100 bases:

>100_bases
GAAGGCGCCCGAGCCCGAGGCGATCGCCGCATGAGCTTCGCCATCTTTGCGCCTGAAACCTCGGCAGATTTCCGCCGTTG
ATCGGCTTTCCGGAGACCGC

Downstream 100 bases:

>100_bases
GACGCCTCGTGGCGCGGGGCGGCTTTGTGCTAAGCCGCAGCTCATGGCCGACCTCTTCGAAGCCGCGGGCCTGACGCCCC
AGCAGCCATCGCCGCTGGCC

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MRATRVLIPACALMMAAAAPLGVAAQVQSNRVPPTSAVAMKSSFAPVVKRAAPAVVNISARRLVRQQTDPFWQLFGLGAP
RARIANSLGSGVIVRPDGIIVTNNHVVENGQEITVALADRREFPARILLADPRTDLAVLKIDVPAGERLPVLPIDDSGDT
EVGDLVLAIGDPFGVGQTVTNGIVSAINRTPDDDGASAYIQTDAAINPGNSGGALVDMDGDLIGVNSFILSRSGTSSGVG
FAVPAAVVRRVVETAAGGGRAVVRPWLGARTQTVTAEIARTLGMARPQGALVADVWPGGAAFRAGLRQGDVVTEVDGRPV
TDAASLNYAFATRRPGDTVRLTVRRDAGREQTLEVRAEAPPASPARDERTIEGQNPLSGATVVNLSPAVADELGLDPFAG
RGVLISRLDRGFAVGAGFRPGDIIRGVNGRRVESVRELTAALETPSRGWQIAFERGGQLITARF

Sequences:

>Translated_464_residues
MRATRVLIPACALMMAAAAPLGVAAQVQSNRVPPTSAVAMKSSFAPVVKRAAPAVVNISARRLVRQQTDPFWQLFGLGAP
RARIANSLGSGVIVRPDGIIVTNNHVVENGQEITVALADRREFPARILLADPRTDLAVLKIDVPAGERLPVLPIDDSGDT
EVGDLVLAIGDPFGVGQTVTNGIVSAINRTPDDDGASAYIQTDAAINPGNSGGALVDMDGDLIGVNSFILSRSGTSSGVG
FAVPAAVVRRVVETAAGGGRAVVRPWLGARTQTVTAEIARTLGMARPQGALVADVWPGGAAFRAGLRQGDVVTEVDGRPV
TDAASLNYAFATRRPGDTVRLTVRRDAGREQTLEVRAEAPPASPARDERTIEGQNPLSGATVVNLSPAVADELGLDPFAG
RGVLISRLDRGFAVGAGFRPGDIIRGVNGRRVESVRELTAALETPSRGWQIAFERGGQLITARF
>Mature_464_residues
MRATRVLIPACALMMAAAAPLGVAAQVQSNRVPPTSAVAMKSSFAPVVKRAAPAVVNISARRLVRQQTDPFWQLFGLGAP
RARIANSLGSGVIVRPDGIIVTNNHVVENGQEITVALADRREFPARILLADPRTDLAVLKIDVPAGERLPVLPIDDSGDT
EVGDLVLAIGDPFGVGQTVTNGIVSAINRTPDDDGASAYIQTDAAINPGNSGGALVDMDGDLIGVNSFILSRSGTSSGVG
FAVPAAVVRRVVETAAGGGRAVVRPWLGARTQTVTAEIARTLGMARPQGALVADVWPGGAAFRAGLRQGDVVTEVDGRPV
TDAASLNYAFATRRPGDTVRLTVRRDAGREQTLEVRAEAPPASPARDERTIEGQNPLSGATVVNLSPAVADELGLDPFAG
RGVLISRLDRGFAVGAGFRPGDIIRGVNGRRVESVRELTAALETPSRGWQIAFERGGQLITARF

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=350, Percent_Identity=34.2857142857143, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI24308541, Length=324, Percent_Identity=35.4938271604938, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4506141, Length=326, Percent_Identity=32.8220858895706, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI7019477, Length=331, Percent_Identity=36.2537764350453, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1789629, Length=408, Percent_Identity=36.7647058823529, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1786356, Length=454, Percent_Identity=33.0396475770925, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1789630, Length=326, Percent_Identity=38.3435582822086, Blast_Score=191, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24646839, Length=269, Percent_Identity=35.6877323420074, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 48418; Mature: 48418

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATRVLIPACALMMAAAAPLGVAAQVQSNRVPPTSAVAMKSSFAPVVKRAAPAVVNISA
CCCCCHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHH
RRLVRQQTDPFWQLFGLGAPRARIANSLGSGVIVRPDGIIVTNNHVVENGQEITVALADR
HHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCEEECCCCEEEECCEEEECCCEEEEEEECC
REFPARILLADPRTDLAVLKIDVPAGERLPVLPIDDSGDTEVGDLVLAIGDPFGVGQTVT
CCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCHHHH
NGIVSAINRTPDDDGASAYIQTDAAINPGNSGGALVDMDGDLIGVNSFILSRSGTSSGVG
HHHHHHHCCCCCCCCCEEEEEECCEECCCCCCCEEEECCCCEEECCCEEEECCCCCCCCC
FAVPAAVVRRVVETAAGGGRAVVRPWLGARTQTVTAEIARTLGMARPQGALVADVWPGGA
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHH
AFRAGLRQGDVVTEVDGRPVTDAASLNYAFATRRPGDTVRLTVRRDAGREQTLEVRAEAP
HHHHCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCEEEEEECCC
PASPARDERTIEGQNPLSGATVVNLSPAVADELGLDPFAGRGVLISRLDRGFAVGAGFRP
CCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCEEECCCCCEEECCCCCC
GDIIRGVNGRRVESVRELTAALETPSRGWQIAFERGGQLITARF
HHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEC
>Mature Secondary Structure
MRATRVLIPACALMMAAAAPLGVAAQVQSNRVPPTSAVAMKSSFAPVVKRAAPAVVNISA
CCCCCHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHH
RRLVRQQTDPFWQLFGLGAPRARIANSLGSGVIVRPDGIIVTNNHVVENGQEITVALADR
HHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCEEECCCCEEEECCEEEECCCEEEEEEECC
REFPARILLADPRTDLAVLKIDVPAGERLPVLPIDDSGDTEVGDLVLAIGDPFGVGQTVT
CCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCHHHH
NGIVSAINRTPDDDGASAYIQTDAAINPGNSGGALVDMDGDLIGVNSFILSRSGTSSGVG
HHHHHHHCCCCCCCCCEEEEEECCEECCCCCCCEEEECCCCEEECCCEEEECCCCCCCCC
FAVPAAVVRRVVETAAGGGRAVVRPWLGARTQTVTAEIARTLGMARPQGALVADVWPGGA
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHH
AFRAGLRQGDVVTEVDGRPVTDAASLNYAFATRRPGDTVRLTVRRDAGREQTLEVRAEAP
HHHHCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCEEEEEECCC
PASPARDERTIEGQNPLSGATVVNLSPAVADELGLDPFAGRGVLISRLDRGFAVGAGFRP
CCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCEEECCCCCEEECCCCCC
GDIIRGVNGRRVESVRELTAALETPSRGWQIAFERGGQLITARF
HHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]