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The map label for this gene is ctrA [H]

Identifier: 197104317

GI number: 197104317

Start: 942503

End: 943198

Strand: Reverse

Name: ctrA [H]

Synonym: PHZ_c0851

Alternate gene names: 197104317

Gene position: 943198-942503 (Counterclockwise)

Preceding gene: 197104321

Following gene: 197104316

Centisome position: 23.6

GC content: 63.07

Gene sequence:

>696_bases
ATGCGCGTACTGTTGATCGAGGACGACAGCGCGACCGCGCAAAGCATCGAGCTGATGCTGAAGTCCGAAGGCTTCAACGT
CTACACCACCGATCTCGGTGAGGAAGGCGTCGATCTCGGCAAAATCTACGACTACGACCTGATCCTGCTGGACCTGAACC
TGCCGGACATGAGCGGCATGGACGTGCTGCGCACGCTGCGGGTCGGCAAGATCAACACCCCGATCATGATCCTGTCGGGC
ACCGCCGAGATCGAGACGAAGGTGAAGACCTTCACGGGCGGCGCCGACGACTACATGACCAAGCCGTTCCACAAGGACGA
GCTGGTCGCCCGCATCCACGCCGTGGTCCGCCGCTCGAAGGGCCACGCGCAGTCGGTCATCAAGACCGGCGACATCACGG
TCAACCTGGACGCCAAGACGGTCGAGGTGAACGGCATCCGCGTCCACCTGACCGGCAAGGAATACCAGATGCTGGAGCTC
CTCTCCCTGCGGAAGGGCACGACCCTGACCAAGGAGATGTTCCTGAACCACCTCTACGGCGGCATGGACGAGCCCGAGCT
GAAGATCATCGACGTGTTCATCTGCAAGCTGCGCAAGAAGCTGGCCGCCGCCGCCGACGGCAAGCACCACATCGAGACGG
TGTGGGGCCGCGGCTACGTCCTGCGCGACCCGCAGGAAGGCGTGATCGCCGCCTAA

Upstream 100 bases:

>100_bases
TAACCAGTCTTAAATTAACTCGGCGGCAAGATTGCCGGTGAGGTCCGGGGCGGATTCTGTGAATTCGCAGGGGTTTGCGG
GTACTCGTTAGGAGAGGCGA

Downstream 100 bases:

>100_bases
GGTTCAGTTCGAGGAGAGTCACGGAACGCCCGCCCTCACCGGCGGGCGTTTTCGTTTGCGCGCCGCCGGGCTAGCCTGCC
GAAAAGGGATCGGGGGAGAC

Product: cell cycle transcriptional regulator CtrA

Products: NA

Alternate protein names: Response regulator SokA [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRVLLIEDDSATAQSIELMLKSEGFNVYTTDLGEEGVDLGKIYDYDLILLDLNLPDMSGMDVLRTLRVGKINTPIMILSG
TAEIETKVKTFTGGADDYMTKPFHKDELVARIHAVVRRSKGHAQSVIKTGDITVNLDAKTVEVNGIRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLAAAADGKHHIETVWGRGYVLRDPQEGVIAA

Sequences:

>Translated_231_residues
MRVLLIEDDSATAQSIELMLKSEGFNVYTTDLGEEGVDLGKIYDYDLILLDLNLPDMSGMDVLRTLRVGKINTPIMILSG
TAEIETKVKTFTGGADDYMTKPFHKDELVARIHAVVRRSKGHAQSVIKTGDITVNLDAKTVEVNGIRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLAAAADGKHHIETVWGRGYVLRDPQEGVIAA
>Mature_231_residues
MRVLLIEDDSATAQSIELMLKSEGFNVYTTDLGEEGVDLGKIYDYDLILLDLNLPDMSGMDVLRTLRVGKINTPIMILSG
TAEIETKVKTFTGGADDYMTKPFHKDELVARIHAVVRRSKGHAQSVIKTGDITVNLDAKTVEVNGIRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLAAAADGKHHIETVWGRGYVLRDPQEGVIAA

Specific function: Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle, including cell division, stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.7826086956522, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.1111111111111, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.1266968325792, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.9366515837104, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=32.7272727272727, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=31.5068493150685, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.8947368421053, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.5154185022026, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=30.316742081448, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=29.2792792792793, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=28.6363636363636, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=25.2212389380531, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=29.9065420560748, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=25.625, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=133, Percent_Identity=27.0676691729323, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=24.1525423728814, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25701; Mature: 25701

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDSATAQSIELMLKSEGFNVYTTDLGEEGVDLGKIYDYDLILLDLNLPDMSGM
CEEEEEECCCCCHHHEEEEEECCCCEEEEECCCCCCCCCCEEECEEEEEEEECCCCCCCH
DVLRTLRVGKINTPIMILSGTAEIETKVKTFTGGADDYMTKPFHKDELVARIHAVVRRSK
HHHHHHHCCCCCCCEEEEECCCEEEEEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHCCC
GHAQSVIKTGDITVNLDAKTVEVNGIRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHHHEEECCEEEEECCEEEEECCEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLAAAADGKHHIETVWGRGYVLRDPQEGVIAA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCEEEECCCCCCCCC
>Mature Secondary Structure
MRVLLIEDDSATAQSIELMLKSEGFNVYTTDLGEEGVDLGKIYDYDLILLDLNLPDMSGM
CEEEEEECCCCCHHHEEEEEECCCCEEEEECCCCCCCCCCEEECEEEEEEEECCCCCCCH
DVLRTLRVGKINTPIMILSGTAEIETKVKTFTGGADDYMTKPFHKDELVARIHAVVRRSK
HHHHHHHCCCCCCCEEEEECCCEEEEEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHCCC
GHAQSVIKTGDITVNLDAKTVEVNGIRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHHHEEECCEEEEECCEEEEECCEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLAAAADGKHHIETVWGRGYVLRDPQEGVIAA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8548829 [H]