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The map label for this gene is arcB [H]

Identifier: 197103756

GI number: 197103756

Start: 283481

End: 285847

Strand: Reverse

Name: arcB [H]

Synonym: PHZ_c0290

Alternate gene names: 197103756

Gene position: 285847-283481 (Counterclockwise)

Preceding gene: 197103757

Following gene: 197103755

Centisome position: 7.15

GC content: 72.62

Gene sequence:

>2367_bases
ATGGCCCGGAAGAGCGCGACACGCGCCGCCGACAGGGCTGAGATGGTCTCGTGGCTGTTCGAGCACAGCCGCGACCTCAT
GCACGTGGTCGGCCCCGACCGCTGCATCCGCCTCGTCAATCCCGCCTGGACCGAACTCACCGGCTGGCGCGAGGACGAGC
TGATCGGCCGCCGCGCCATCGAGGTCTTCCACCCCGACGACCGGCCGCACATGCTGGCGCGCGTGGCCCAGTCGAAGGTG
GGCGTGGTCTATGAATCCGAGGCCCGCGTCCTCCTGAAGGACGGCTCCTCGTGCTGGGTCGCCGCGCGGCGCCAGATGAT
GCCGGACGGCTCGCACATCGTGTCCATGCGGGACGCCACCGAGCAGCGCGCCCACCGCGACGAGATCGACAACGCCCGCC
GCACCCGCAAGGCGCTGGGCGCCTCGGCCGGCATCGGCATCTGGACCTACGAGCCCGCGCTGGGGCGCATCTGGTGGTCG
GACGAGATCGTCGCGATGGTCGGCTTCGACCCGCGCGAGAACGACACGCCCGAGGCCTTCCGCGCGATGATGCATCCGCG
CGACCGCGCCCGGACCATGCAGGCCTTCGCCCGGGCGGTCGAGAACGGCGAGCCGCTGCAGCGCGAGCACCGCGTCTGGG
CCCGCGGGCGCTGGATGGTGGTGCGCGTGACGGTCACCACCGAGCCGCGGCCGGGCGGGGTCTTCGCCCTGAAGGGCATC
TCCGAGGACATCACCGAGCTGGCGGCCGCCCGCGACGCCGCGCGGCACGGCGAGCAGCAGGCCCGCAAGGCCCGCCGCGA
GGCCCAGGTCAACGCCCGGCGCCTGAAGATGGCGCTCGAGGCCGCCGAGGCCGGGGTCTACGAGATCGACCACGTGGCCC
GCACGTTCTGGGCCTCGCCCGAGTTCGAGCGGATCACCGGCCGGCGCGGCTCCAGCTACGAGGAGGCCGTCCACCTCAGC
TATCCGGGCTTCCATCCCGAGGACCTGCCGCACGTGCGCGCCTCGTTCCGCGCCCTGCATCGCGGGGACAAGAAGTCGGG
CGAATCCTTCGAGGCGCGCATCGTCCGGCCGGACGGCGCCGAGCGCTGGGTGCGCGTCTACCACCACCTCAAGGTCGGCC
GGAACGGGCGCTGGCTGAAGGCCGTGGGCCTGGTGCAGGACTGCGACGCCCACAAGCGCCAGGAACTGGCCCTGAAGGAG
GCCCAGCGCGCCGCCGAGGCGGCCGGCGAAGCCAAGGGCGCCTTCCTCGCCAACATGAGCCACGAGATCCGCACCCCGCT
GAACGGGGTGATGGGCGTGCTGCATATCCTGAAGTCCGAGCAGCTCACCGACGAGGGCCGCAGCCTGCTGGACGAGGCGC
TGTCGTGCGGCCAGATGCTGGCCGAGCTGCTGAACGACGTCATCGACTTCTCGAAGATCGAGGCCGGCCGGCTGGAGCTG
GCCTGCGAGCCGGTGGACCCCAAGGCGCTGGTCGAGGGCGTCGCCCGCCTGCTGAAGCCCCAGGCCCAGGCCAAGGGCCT
GCAGCTGATCGTCGACGCCGACGCGCGGATGGGCTGGGTGCGCTCGGACCCGGTGCGCCTGCGCCAGGCGCTGTTCAACC
TGGTCGGCAATGCGGTGAAGTTCACCGAGAAGGGCCATGTGGTGATCCGCTGCCGCCTCGCCGACGCGGGCGTGCTGCGC
TTCGAGGTCGAGGACACCGGCGTCGGCATCCCCGAGGCGGCGCAGGCGCGGCTGTTCCAGCGGTTCAACCAGGCCGACGC
CTCCACGACCCGCAAGTTCGGCGGCTCGGGCCTGGGCCTGGCCATCACCAAGCGGTTGGCCGAGATGATGAACGGCCAGG
TGGGCTTCACCTCGGCCGAGGGCCGCGGTTCGACCTTCTGGCTGGAGGTGGCGGCCGAGCCGGCCGAGGCGCAGGCGCCG
GCGTGCGAGGCGCCGCACGCGGTGCTGGAGGGCCTGCGCGTCCTCGTGGTCGAGGACAACGCCACCAACCGGCTGATCGC
CACCAAGCTGCTCGAGAACCTGGGGGCCTCGGTCGAGACCGCCGCCGACGGCTACCTGGGCGTGGAGGCGGCCGCCCGCG
GCGGCTTCGACCTGATCCTGATGGACGTGCAGATGCCCGGCATCGACGGGCTGGAGGCCGCCCGCCGCATCCGCGCGCTG
GGCGGGAACGTCGCCGCCATCCCGATCGTGGCCCTCACCGCCAACGTGCTCTCGCACCAGCGGCAGTCCTACCTGGAGGC
CGGCATGGACGGGGTGGTCGGCAAGCCCATCTCCCCCGCCGCCCTGCTCTCCGAGATCGCCCGGCTGAGCGCCCCTGTCG
AACCTGCGGTCGAAGCGGCGGACGACGCCGACACCGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGGCCAGGGCGGCCCGCGCAGATTGGCCGCAGGCCCTCCACAACTTTGCGTTTACCCCCACAGTGTAAGCGTGCCCCGC
TTTCGTGGGGGAAACCTTGG

Downstream 100 bases:

>100_bases
CCCCTCGCGCGCCGATCCGCCCCGACGCCTTCCACCCGTCGGCGAACCGGTGTTACAGCAGGCGCAACGACACCTTGGGG
GGAGATGACGGGCATGGCGG

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 787

Protein sequence:

>788_residues
MARKSATRAADRAEMVSWLFEHSRDLMHVVGPDRCIRLVNPAWTELTGWREDELIGRRAIEVFHPDDRPHMLARVAQSKV
GVVYESEARVLLKDGSSCWVAARRQMMPDGSHIVSMRDATEQRAHRDEIDNARRTRKALGASAGIGIWTYEPALGRIWWS
DEIVAMVGFDPRENDTPEAFRAMMHPRDRARTMQAFARAVENGEPLQREHRVWARGRWMVVRVTVTTEPRPGGVFALKGI
SEDITELAAARDAARHGEQQARKARREAQVNARRLKMALEAAEAGVYEIDHVARTFWASPEFERITGRRGSSYEEAVHLS
YPGFHPEDLPHVRASFRALHRGDKKSGESFEARIVRPDGAERWVRVYHHLKVGRNGRWLKAVGLVQDCDAHKRQELALKE
AQRAAEAAGEAKGAFLANMSHEIRTPLNGVMGVLHILKSEQLTDEGRSLLDEALSCGQMLAELLNDVIDFSKIEAGRLEL
ACEPVDPKALVEGVARLLKPQAQAKGLQLIVDADARMGWVRSDPVRLRQALFNLVGNAVKFTEKGHVVIRCRLADAGVLR
FEVEDTGVGIPEAAQARLFQRFNQADASTTRKFGGSGLGLAITKRLAEMMNGQVGFTSAEGRGSTFWLEVAAEPAEAQAP
ACEAPHAVLEGLRVLVVEDNATNRLIATKLLENLGASVETAADGYLGVEAAARGGFDLILMDVQMPGIDGLEAARRIRAL
GGNVAAIPIVALTANVLSHQRQSYLEAGMDGVVGKPISPAALLSEIARLSAPVEPAVEAADDADTAAA

Sequences:

>Translated_788_residues
MARKSATRAADRAEMVSWLFEHSRDLMHVVGPDRCIRLVNPAWTELTGWREDELIGRRAIEVFHPDDRPHMLARVAQSKV
GVVYESEARVLLKDGSSCWVAARRQMMPDGSHIVSMRDATEQRAHRDEIDNARRTRKALGASAGIGIWTYEPALGRIWWS
DEIVAMVGFDPRENDTPEAFRAMMHPRDRARTMQAFARAVENGEPLQREHRVWARGRWMVVRVTVTTEPRPGGVFALKGI
SEDITELAAARDAARHGEQQARKARREAQVNARRLKMALEAAEAGVYEIDHVARTFWASPEFERITGRRGSSYEEAVHLS
YPGFHPEDLPHVRASFRALHRGDKKSGESFEARIVRPDGAERWVRVYHHLKVGRNGRWLKAVGLVQDCDAHKRQELALKE
AQRAAEAAGEAKGAFLANMSHEIRTPLNGVMGVLHILKSEQLTDEGRSLLDEALSCGQMLAELLNDVIDFSKIEAGRLEL
ACEPVDPKALVEGVARLLKPQAQAKGLQLIVDADARMGWVRSDPVRLRQALFNLVGNAVKFTEKGHVVIRCRLADAGVLR
FEVEDTGVGIPEAAQARLFQRFNQADASTTRKFGGSGLGLAITKRLAEMMNGQVGFTSAEGRGSTFWLEVAAEPAEAQAP
ACEAPHAVLEGLRVLVVEDNATNRLIATKLLENLGASVETAADGYLGVEAAARGGFDLILMDVQMPGIDGLEAARRIRAL
GGNVAAIPIVALTANVLSHQRQSYLEAGMDGVVGKPISPAALLSEIARLSAPVEPAVEAADDADTAAA
>Mature_787_residues
ARKSATRAADRAEMVSWLFEHSRDLMHVVGPDRCIRLVNPAWTELTGWREDELIGRRAIEVFHPDDRPHMLARVAQSKVG
VVYESEARVLLKDGSSCWVAARRQMMPDGSHIVSMRDATEQRAHRDEIDNARRTRKALGASAGIGIWTYEPALGRIWWSD
EIVAMVGFDPRENDTPEAFRAMMHPRDRARTMQAFARAVENGEPLQREHRVWARGRWMVVRVTVTTEPRPGGVFALKGIS
EDITELAAARDAARHGEQQARKARREAQVNARRLKMALEAAEAGVYEIDHVARTFWASPEFERITGRRGSSYEEAVHLSY
PGFHPEDLPHVRASFRALHRGDKKSGESFEARIVRPDGAERWVRVYHHLKVGRNGRWLKAVGLVQDCDAHKRQELALKEA
QRAAEAAGEAKGAFLANMSHEIRTPLNGVMGVLHILKSEQLTDEGRSLLDEALSCGQMLAELLNDVIDFSKIEAGRLELA
CEPVDPKALVEGVARLLKPQAQAKGLQLIVDADARMGWVRSDPVRLRQALFNLVGNAVKFTEKGHVVIRCRLADAGVLRF
EVEDTGVGIPEAAQARLFQRFNQADASTTRKFGGSGLGLAITKRLAEMMNGQVGFTSAEGRGSTFWLEVAAEPAEAQAPA
CEAPHAVLEGLRVLVVEDNATNRLIATKLLENLGASVETAADGYLGVEAAARGGFDLILMDVQMPGIDGLEAARRIRALG
GNVAAIPIVALTANVLSHQRQSYLEAGMDGVVGKPISPAALLSEIARLSAPVEPAVEAADDADTAAA

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=467, Percent_Identity=35.117773019272, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI1788713, Length=382, Percent_Identity=33.7696335078534, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=43.3884297520661, Blast_Score=196, Evalue=7e-51,
Organism=Escherichia coli, GI87081816, Length=370, Percent_Identity=33.7837837837838, Blast_Score=195, Evalue=9e-51,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=35.7142857142857, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=32.0833333333333, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=32.4786324786325, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=24.812030075188, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=260, Percent_Identity=29.2307692307692, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788393, Length=204, Percent_Identity=29.9019607843137, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=222, Percent_Identity=28.3783783783784, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=28.2296650717703, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=288, Percent_Identity=26.0416666666667, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790551, Length=220, Percent_Identity=28.1818181818182, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=24.901185770751, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=147, Percent_Identity=29.9319727891156, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322044, Length=73, Percent_Identity=43.8356164383562, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86438; Mature: 86307

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKSATRAADRAEMVSWLFEHSRDLMHVVGPDRCIRLVNPAWTELTGWREDELIGRRAI
CCCCCHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHHCCCCHHHHCCCCHHHHHHHHHE
EVFHPDDRPHMLARVAQSKVGVVYESEARVLLKDGSSCWVAARRQMMPDGSHIVSMRDAT
EEECCCCCHHHHHHHHHHHCCEEEECCCEEEEECCCCHHHHHHHHCCCCCCCEEEEHHHH
EQRAHRDEIDNARRTRKALGASAGIGIWTYEPALGRIWWSDEIVAMVGFDPRENDTPEAF
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCEEEEECCCCCCCCCHHHH
RAMMHPRDRARTMQAFARAVENGEPLQREHRVWARGRWMVVRVTVTTEPRPGGVFALKGI
HHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCCEEEECCC
SEDITELAAARDAARHGEQQARKARREAQVNARRLKMALEAAEAGVYEIDHVARTFWASP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
EFERITGRRGSSYEEAVHLSYPGFHPEDLPHVRASFRALHRGDKKSGESFEARIVRPDGA
CHHHHCCCCCCCHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCH
ERWVRVYHHLKVGRNGRWLKAVGLVQDCDAHKRQELALKEAQRAAEAAGEAKGAFLANMS
HHHHHHHHHHHCCCCCCEEEECCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
HEIRTPLNGVMGVLHILKSEQLTDEGRSLLDEALSCGQMLAELLNDVIDFSKIEAGRLEL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ACEPVDPKALVEGVARLLKPQAQAKGLQLIVDADARMGWVRSDPVRLRQALFNLVGNAVK
EECCCCHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHE
FTEKGHVVIRCRLADAGVLRFEVEDTGVGIPEAAQARLFQRFNQADASTTRKFGGSGLGL
EECCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCHH
AITKRLAEMMNGQVGFTSAEGRGSTFWLEVAAEPAEAQAPACEAPHAVLEGLRVLVVEDN
HHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCEEEEEECC
ATNRLIATKLLENLGASVETAADGYLGVEAAARGGFDLILMDVQMPGIDGLEAARRIRAL
CCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHH
GGNVAAIPIVALTANVLSHQRQSYLEAGMDGVVGKPISPAALLSEIARLSAPVEPAVEAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCC
DDADTAAA
CCCCCCCC
>Mature Secondary Structure 
ARKSATRAADRAEMVSWLFEHSRDLMHVVGPDRCIRLVNPAWTELTGWREDELIGRRAI
CCCCHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHHCCCCHHHHCCCCHHHHHHHHHE
EVFHPDDRPHMLARVAQSKVGVVYESEARVLLKDGSSCWVAARRQMMPDGSHIVSMRDAT
EEECCCCCHHHHHHHHHHHCCEEEECCCEEEEECCCCHHHHHHHHCCCCCCCEEEEHHHH
EQRAHRDEIDNARRTRKALGASAGIGIWTYEPALGRIWWSDEIVAMVGFDPRENDTPEAF
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCEEEEECCCCCCCCCHHHH
RAMMHPRDRARTMQAFARAVENGEPLQREHRVWARGRWMVVRVTVTTEPRPGGVFALKGI
HHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCCEEEECCC
SEDITELAAARDAARHGEQQARKARREAQVNARRLKMALEAAEAGVYEIDHVARTFWASP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
EFERITGRRGSSYEEAVHLSYPGFHPEDLPHVRASFRALHRGDKKSGESFEARIVRPDGA
CHHHHCCCCCCCHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCH
ERWVRVYHHLKVGRNGRWLKAVGLVQDCDAHKRQELALKEAQRAAEAAGEAKGAFLANMS
HHHHHHHHHHHCCCCCCEEEECCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
HEIRTPLNGVMGVLHILKSEQLTDEGRSLLDEALSCGQMLAELLNDVIDFSKIEAGRLEL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ACEPVDPKALVEGVARLLKPQAQAKGLQLIVDADARMGWVRSDPVRLRQALFNLVGNAVK
EECCCCHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHE
FTEKGHVVIRCRLADAGVLRFEVEDTGVGIPEAAQARLFQRFNQADASTTRKFGGSGLGL
EECCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCHH
AITKRLAEMMNGQVGFTSAEGRGSTFWLEVAAEPAEAQAPACEAPHAVLEGLRVLVVEDN
HHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCEEEEEECC
ATNRLIATKLLENLGASVETAADGYLGVEAAARGGFDLILMDVQMPGIDGLEAARRIRAL
CCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHH
GGNVAAIPIVALTANVLSHQRQSYLEAGMDGVVGKPISPAALLSEIARLSAPVEPAVEAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCC
DDADTAAA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]