BacMap

Definition	Phenylobacterium zucineum HLK1, complete genome.
Accession	NC_011144
Length	3,996,255

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The map label for this gene is kduD [H]

Identifier: 197103751

GI number: 197103751

Start: 278034

End: 278807

Strand: Reverse

Name: kduD [H]

Synonym: PHZ_c0285

Alternate gene names: 197103751

Gene position: 278807-278034 (Counterclockwise)

Preceding gene: 197103755

Following gene: 197103750

Centisome position: 6.98

GC content: 71.83

Gene sequence:

>774_bases
ATGAGCTATCCGCTGCCGAACATCTCCACCGACCTGTCGGGCCAGACCGCCTTCGTGACGGGCGCCTCTTCGGGACTCGG
GAACCGCTTCGCCCGGGTGTTGGCCGCCGCCGGGGCCAAGGTGGCGATCGCCGCCCGGCGCGCCGACCGCCTCGAAGCCC
TGGCCGGCGAGATCCGCGCGGCCGGCGGCGAGGCCTTCCCCGTCGAGGTGGACGTGTCCGACGATGCGGCGCTGCCCGAC
GCCGTCGCCAGGGCGGAGGCGGCCCTCGGGCTCGTCACCATCCTCGTCAACAACGCCGGCATCCCCGACGCCCAGCGGGC
CACCAAGATGCCGCCCGAGCTGATCAACCGCGTCCTGGACGTGAACGTGCGCGCGCCCTTCGTGCTGTCGTGCGAGGTCG
CCCGCCGGCTGATGGCGGCCAAGCGGCCGGGGCGGGTCGTCAACATCGCCTCCATCGCGGCCTTCGACTATTCCGGCGGC
GGGGCGGCGCTCTACTCGGTCAGCAAGGCCGCGGTGGTCCGGATGACCGAGGCGCTGGCGGTGGAGTGGTCGGGGTTCAA
TATCAACGTCAACGCCATCGCCCCGGGCGCCTTCGCCTCCGAGATGATGGACGGCATGCTGCAGCGGGTGGGCGACATCT
CGCAGCACTTCCCGCGCAAGCGGATCGGCGATCCGGCCCAGCTCGACAGCACCCTGCTCTATCTCGTCTCGCCCGCGTCC
GACGCGGTCACCGGAACCTGCATCAAGGTGGACGACGGCCAGGGCCGCCGCTGA

Upstream 100 bases:

>100_bases
CCGCGGCGCGGATGAACGGCGGCTGACCGCGGATTCGCCCCTCGCCAGACGCGGCGTCAGCCTGTTCAGCTTGGGGGACG
CCGATCCGGAGACCGCCCCC

Downstream 100 bases:

>100_bases
TCCGCCGCAACCCCAACGAGGAGGAAGACCCCATGAGCGCCTTCAAGGACGGCCTGCTGGCCGGCAAGACGGCCTTCGTC
GCCGGCGGCACCAGCGGCAT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSYPLPNISTDLSGQTAFVTGASSGLGNRFARVLAAAGAKVAIAARRADRLEALAGEIRAAGGEAFPVEVDVSDDAALPD
AVARAEAALGLVTILVNNAGIPDAQRATKMPPELINRVLDVNVRAPFVLSCEVARRLMAAKRPGRVVNIASIAAFDYSGG
GAALYSVSKAAVVRMTEALAVEWSGFNINVNAIAPGAFASEMMDGMLQRVGDISQHFPRKRIGDPAQLDSTLLYLVSPAS
DAVTGTCIKVDDGQGRR

Sequences:

>Translated_257_residues
MSYPLPNISTDLSGQTAFVTGASSGLGNRFARVLAAAGAKVAIAARRADRLEALAGEIRAAGGEAFPVEVDVSDDAALPD
AVARAEAALGLVTILVNNAGIPDAQRATKMPPELINRVLDVNVRAPFVLSCEVARRLMAAKRPGRVVNIASIAAFDYSGG
GAALYSVSKAAVVRMTEALAVEWSGFNINVNAIAPGAFASEMMDGMLQRVGDISQHFPRKRIGDPAQLDSTLLYLVSPAS
DAVTGTCIKVDDGQGRR
>Mature_256_residues
SYPLPNISTDLSGQTAFVTGASSGLGNRFARVLAAAGAKVAIAARRADRLEALAGEIRAAGGEAFPVEVDVSDDAALPDA
VARAEAALGLVTILVNNAGIPDAQRATKMPPELINRVLDVNVRAPFVLSCEVARRLMAAKRPGRVVNIASIAAFDYSGGG
AALYSVSKAAVVRMTEALAVEWSGFNINVNAIAPGAFASEMMDGMLQRVGDISQHFPRKRIGDPAQLDSTLLYLVSPASD
AVTGTCIKVDDGQGRR

Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=269, Percent_Identity=28.996282527881, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=28.936170212766, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=29.2, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=29.7959183673469, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=31.0756972111554, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=28.3950617283951, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=30.1204819277108, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4503301, Length=249, Percent_Identity=26.5060240963855, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=32.8125, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4758504, Length=231, Percent_Identity=32.9004329004329, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254986, Length=201, Percent_Identity=31.8407960199005, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4557649, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI209862901, Length=202, Percent_Identity=29.7029702970297, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI19923983, Length=202, Percent_Identity=29.7029702970297, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI157739938, Length=189, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=265, Percent_Identity=26.0377358490566, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=36.5461847389558, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=33.6032388663968, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=32.6530612244898, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=32.6530612244898, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=30.6772908366534, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=33.1967213114754, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=33.0645161290323, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=29.3877551020408, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=29.1828793774319, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=30.9236947791165, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=30.3867403314917, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=34.1269841269841, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=31.3492063492063, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=29.1338582677165, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=34.251968503937, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=28.6821705426357, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=27.3076923076923, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=30.4182509505703, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=29.0697674418605, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=30.1526717557252, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=28.735632183908, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=34.251968503937, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=30.5019305019305, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=28.5140562248996, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=29.7029702970297, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=27.0916334661355, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=27.6923076923077, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=25.7692307692308, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=29.7619047619048, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=202, Percent_Identity=28.7128712871287, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=202, Percent_Identity=29.7029702970297, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=216, Percent_Identity=28.2407407407407, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=28.735632183908, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=192, Percent_Identity=30.2083333333333, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=27.8884462151394, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=185, Percent_Identity=34.0540540540541, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=33.7962962962963, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=30.4182509505703, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71997099, Length=209, Percent_Identity=31.1004784688995, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=26.8199233716475, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=24.3445692883895, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=206, Percent_Identity=27.6699029126214, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558628, Length=192, Percent_Identity=30.7291666666667, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=29.5336787564767, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=254, Percent_Identity=27.5590551181102, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=254, Percent_Identity=27.5590551181102, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=32.8282828282828, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=31.6831683168317, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=26.0700389105058, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=34.9397590361446, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=34.251968503937, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=32, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=31.7073170731707, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=26.8595041322314, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17737361, Length=226, Percent_Identity=33.6283185840708, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641232, Length=214, Percent_Identity=30.3738317757009, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859837, Length=205, Percent_Identity=33.1707317073171, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=26.3779527559055, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI161076933, Length=203, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24584748, Length=203, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24584752, Length=203, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=29.5918367346939, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571387, Length=206, Percent_Identity=32.0388349514563, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=30.6122448979592, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007234, Length=198, Percent_Identity=30.8080808080808, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584744, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574402, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648944, Length=205, Percent_Identity=27.3170731707317, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641388, Length=201, Percent_Identity=31.8407960199005, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=28.0632411067194, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=204, Percent_Identity=27.9411764705882, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24648693, Length=202, Percent_Identity=32.1782178217822, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355889, Length=202, Percent_Identity=32.1782178217822, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007238, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24586328, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011286
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.127 [H]

Molecular weight: Translated: 26735; Mature: 26604

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYPLPNISTDLSGQTAFVTGASSGLGNRFARVLAAAGAKVAIAARRADRLEALAGEIRA
CCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHH
AGGEAFPVEVDVSDDAALPDAVARAEAALGLVTILVNNAGIPDAQRATKMPPELINRVLD
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCHHHHHCCCHHHHHHHHC
VNVRAPFVLSCEVARRLMAAKRPGRVVNIASIAAFDYSGGGAALYSVSKAAVVRMTEALA
CCCCCCEEEEHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHE
VEWSGFNINVNAIAPGAFASEMMDGMLQRVGDISQHFPRKRIGDPAQLDSTLLYLVSPAS
EEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCEEEEEECCCC
DAVTGTCIKVDDGQGRR
CCCEEEEEEECCCCCCC
>Mature Secondary Structure 
SYPLPNISTDLSGQTAFVTGASSGLGNRFARVLAAAGAKVAIAARRADRLEALAGEIRA
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHH
AGGEAFPVEVDVSDDAALPDAVARAEAALGLVTILVNNAGIPDAQRATKMPPELINRVLD
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCHHHHHCCCHHHHHHHHC
VNVRAPFVLSCEVARRLMAAKRPGRVVNIASIAAFDYSGGGAALYSVSKAAVVRMTEALA
CCCCCCEEEEHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHE
VEWSGFNINVNAIAPGAFASEMMDGMLQRVGDISQHFPRKRIGDPAQLDSTLLYLVSPAS
EEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCEEEEEECCCC
DAVTGTCIKVDDGQGRR
CCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766386 [H]