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The map label for this gene is yleA [C]

Identifier: 197103594

GI number: 197103594

Start: 121363

End: 122760

Strand: Direct

Name: yleA [C]

Synonym: PHZ_c0128

Alternate gene names: 197103594

Gene position: 121363-122760 (Clockwise)

Preceding gene: 197103593

Following gene: 197103595

Centisome position: 3.04

GC content: 73.18

Gene sequence:

>1398_bases
ATGGCGCGCGGACGGCCACGTGATCATGACCGGCCCGGCGGCCGTCGACTTCCAGGGCGAGCTGCCGTGAGCGGCTTCGA
GGCCCCCTCCGTCTCGACGCGTTCGCGCCGATCCACCTCCCCCCCTTCGCAGGGGAGGAGCGACGTCGACATCGTCACGT
TCGGCTGCCGGCTGAACGCCTACGAGAGCGAGGTCATCCGCAAGCGGGCGGCCGAGGACGGCCTTTCGGACGCCATCGTG
TTCAACACCTGTGCGGTGACGGGCGAGGCGGTGCGCCAGGCCCGGCAGGCGATCCGCAAGGCCCGCCGCGAGCGGCCGGG
CGCGAAGGTGATCGTCACCGGCTGCGCGGCCCAGATCGATCCCGACGCCTTCGCCGCCATGGACGAGGTCGACCTGGTGC
TCGGCAACGCCGAGAAGAGCCAGGCCGGGTCCTATGCGCCGACGGCCGAGGCCGGCCGCGTGCGCGTCAATGACATCATG
AGCGTGCGCGAGACGGCGGGCCATCTCATCGACGGATTGAAAGACCGCGCGCGGGCCTATGTCGAGGTCCAGAACGGCTG
TGACCACCGCTGCACCTTCTGCATCATCCCCTACGGCCGCGGGAACTCCCGCTCGGCGCCCGCCGGCGAGGTGGTCGAGC
AGGTTCGCCGGCTGGCGGGCGAAGGCTACCAGGAGGTCGTGCTCACCGGCGTGGACGTGACGAGCTGGGGCGCCGACCTG
CCGGGCGCCCCGACCCTGGGCCAGCTGGTCGGGCGAATCCTGAAGCTGGCGCCCGGGCTGCCGCGCCTGCGGCTGTCGTC
CATCGACGCGGCCGAGATCGACGCCGACCTGCTGCGGCTCCTCGCCGAGGAGCCCCGGCTGATGCCCTACCTGCACCTCA
GCCTTCAGGCAGGGGACGACATGATCCTGAAGCGCATGAAGCGCCGCCACAGCCGCGCCGACGCGCTGAGGCTCGTCGCC
GACGTGCGCGCGGTGCGCCCCGACGTGGCCTTCGGCGCCGACCTGATCGCCGGTTTCCCGACCGAGACGGACGAGATGTT
CGAGAACACCCTGCGGCTGGTGGAGGAGGCGGGACTCGCGTTCCTGCACGTCTTCCCCTTCAGCCCCAGGCCGGGCACGC
CGGCGGCCCGGATGCCGCAACTGCCGCGCGAGGTGGTGAAGGCTCGCGCCGCCCGCCTGCGCGCCGCCGGCGAGGCCGCC
CTGGACCGCCACCTGGAGGCCCAGGTCGGCCGGACGCTGCTGGGCCTCGTCGAGCGGCCCGGGTTCGCGCGCGCCGAGGA
CTTCACCGAGATCGCCTTCACCGGCGAGGCGGCGGAGGGGGCCGTCGTCGCCCTGGCGGTCACCGCACACGACGGCCGGC
GGGCGATCGCCCGCGTTCAGGAGAGGGGCGCGGCATGA

Upstream 100 bases:

>100_bases
GCGGCACCGGCGCCTGCGCGGCCATGGTGGCCGCCTCGCGCCGCGGCCTGATCGGCCGCCACGCGACGATGGAGCTGGAC
GGCGGCGAGCTGTTCGTCGA

Downstream 100 bases:

>100_bases
GCTGGACCGGCGGATGCCAGTGCGGGAAGGTCCGCTTCCGGGTGGAGGGCGAGCTGGGGCGCGCCAGCATCTGCCACTGC
CGCATGTGCCAGAAGGCGAC

Product: 2-methylthioadenine synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MARGRPRDHDRPGGRRLPGRAAVSGFEAPSVSTRSRRSTSPPSQGRSDVDIVTFGCRLNAYESEVIRKRAAEDGLSDAIV
FNTCAVTGEAVRQARQAIRKARRERPGAKVIVTGCAAQIDPDAFAAMDEVDLVLGNAEKSQAGSYAPTAEAGRVRVNDIM
SVRETAGHLIDGLKDRARAYVEVQNGCDHRCTFCIIPYGRGNSRSAPAGEVVEQVRRLAGEGYQEVVLTGVDVTSWGADL
PGAPTLGQLVGRILKLAPGLPRLRLSSIDAAEIDADLLRLLAEEPRLMPYLHLSLQAGDDMILKRMKRRHSRADALRLVA
DVRAVRPDVAFGADLIAGFPTETDEMFENTLRLVEEAGLAFLHVFPFSPRPGTPAARMPQLPREVVKARAARLRAAGEAA
LDRHLEAQVGRTLLGLVERPGFARAEDFTEIAFTGEAAEGAVVALAVTAHDGRRAIARVQERGAA

Sequences:

>Translated_465_residues
MARGRPRDHDRPGGRRLPGRAAVSGFEAPSVSTRSRRSTSPPSQGRSDVDIVTFGCRLNAYESEVIRKRAAEDGLSDAIV
FNTCAVTGEAVRQARQAIRKARRERPGAKVIVTGCAAQIDPDAFAAMDEVDLVLGNAEKSQAGSYAPTAEAGRVRVNDIM
SVRETAGHLIDGLKDRARAYVEVQNGCDHRCTFCIIPYGRGNSRSAPAGEVVEQVRRLAGEGYQEVVLTGVDVTSWGADL
PGAPTLGQLVGRILKLAPGLPRLRLSSIDAAEIDADLLRLLAEEPRLMPYLHLSLQAGDDMILKRMKRRHSRADALRLVA
DVRAVRPDVAFGADLIAGFPTETDEMFENTLRLVEEAGLAFLHVFPFSPRPGTPAARMPQLPREVVKARAARLRAAGEAA
LDRHLEAQVGRTLLGLVERPGFARAEDFTEIAFTGEAAEGAVVALAVTAHDGRRAIARVQERGAA
>Mature_464_residues
ARGRPRDHDRPGGRRLPGRAAVSGFEAPSVSTRSRRSTSPPSQGRSDVDIVTFGCRLNAYESEVIRKRAAEDGLSDAIVF
NTCAVTGEAVRQARQAIRKARRERPGAKVIVTGCAAQIDPDAFAAMDEVDLVLGNAEKSQAGSYAPTAEAGRVRVNDIMS
VRETAGHLIDGLKDRARAYVEVQNGCDHRCTFCIIPYGRGNSRSAPAGEVVEQVRRLAGEGYQEVVLTGVDVTSWGADLP
GAPTLGQLVGRILKLAPGLPRLRLSSIDAAEIDADLLRLLAEEPRLMPYLHLSLQAGDDMILKRMKRRHSRADALRLVAD
VRAVRPDVAFGADLIAGFPTETDEMFENTLRLVEEAGLAFLHVFPFSPRPGTPAARMPQLPREVVKARAARLRAAGEAAL
DRHLEAQVGRTLLGLVERPGFARAEDFTEIAFTGEAAEGAVVALAVTAHDGRRAIARVQERGAA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=379, Percent_Identity=29.8153034300792, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI28872782, Length=413, Percent_Identity=25.181598062954, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI28872784, Length=413, Percent_Identity=24.9394673123487, Blast_Score=132, Evalue=9e-31,
Organism=Escherichia coli, GI1786882, Length=362, Percent_Identity=28.7292817679558, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1787057, Length=390, Percent_Identity=29.7435897435897, Blast_Score=156, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17553146, Length=386, Percent_Identity=31.0880829015544, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI71996771, Length=220, Percent_Identity=32.2727272727273, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922432, Length=368, Percent_Identity=29.8913043478261, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356207, Length=407, Percent_Identity=26.7813267813268, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 50120; Mature: 49988

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGRPRDHDRPGGRRLPGRAAVSGFEAPSVSTRSRRSTSPPSQGRSDVDIVTFGCRLNA
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCH
YESEVIRKRAAEDGLSDAIVFNTCAVTGEAVRQARQAIRKARRERPGAKVIVTGCAAQID
HHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
PDAFAAMDEVDLVLGNAEKSQAGSYAPTAEAGRVRVNDIMSVRETAGHLIDGLKDRARAY
CHHHHHHHHHHHEECCCCHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEE
VEVQNGCDHRCTFCIIPYGRGNSRSAPAGEVVEQVRRLAGEGYQEVVLTGVDVTSWGADL
EECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEECCCHHCCCCCC
PGAPTLGQLVGRILKLAPGLPRLRLSSIDAAEIDADLLRLLAEEPRLMPYLHLSLQAGDD
CCCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCH
MILKRMKRRHSRADALRLVADVRAVRPDVAFGADLIAGFPTETDEMFENTLRLVEEAGLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHCCCCCCHHHHHHHHHHHHHHCCCE
FLHVFPFSPRPGTPAARMPQLPREVVKARAARLRAAGEAALDRHLEAQVGRTLLGLVERP
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFARAEDFTEIAFTGEAAEGAVVALAVTAHDGRRAIARVQERGAA
CCCCCCCCHHEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ARGRPRDHDRPGGRRLPGRAAVSGFEAPSVSTRSRRSTSPPSQGRSDVDIVTFGCRLNA
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCH
YESEVIRKRAAEDGLSDAIVFNTCAVTGEAVRQARQAIRKARRERPGAKVIVTGCAAQID
HHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
PDAFAAMDEVDLVLGNAEKSQAGSYAPTAEAGRVRVNDIMSVRETAGHLIDGLKDRARAY
CHHHHHHHHHHHEECCCCHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEE
VEVQNGCDHRCTFCIIPYGRGNSRSAPAGEVVEQVRRLAGEGYQEVVLTGVDVTSWGADL
EECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEECCCHHCCCCCC
PGAPTLGQLVGRILKLAPGLPRLRLSSIDAAEIDADLLRLLAEEPRLMPYLHLSLQAGDD
CCCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCH
MILKRMKRRHSRADALRLVADVRAVRPDVAFGADLIAGFPTETDEMFENTLRLVEEAGLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHCCCCCCHHHHHHHHHHHHHHCCCE
FLHVFPFSPRPGTPAARMPQLPREVVKARAARLRAAGEAALDRHLEAQVGRTLLGLVERP
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFARAEDFTEIAFTGEAAEGAVVALAVTAHDGRRAIARVQERGAA
CCCCCCCCHHEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]