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The map label for this gene is lon2 [H]

Identifier: 197103486

GI number: 197103486

Start: 17170

End: 17829

Strand: Direct

Name: lon2 [H]

Synonym: PHZ_c0020

Alternate gene names: 197103486

Gene position: 17170-17829 (Clockwise)

Preceding gene: 197103485

Following gene: 197103487

Centisome position: 0.43

GC content: 70.76

Gene sequence:

>660_bases
ATGGCCGCCTATCGCAGAGCCGCCGACCTGCCGCAGGTGATTCCGGTCTTTCCCCTGGACGGCGCATTGCTGCTGCCGGG
CGGGGACCTGCCGCTGCAGATCTTCGAGCCGCGCTACCTCAACATGATCGACGACGTCATGGGCGGCGACCGGATCATCG
GCATGATCCAGAGCAAGCCGGGCGGCGACCGCACCCGGCCCAAGCTGGCCGACGTCGGCTGCGCGGGCCGGATCACCAGC
TACGCCGAGACCTCGGACGGCCGCTATCTGATCACCCTCACCGGCATCTGCCGCTTCGAGGCGGGCGAGGAGCTGATCCT
GCGCACCCCCTACCGGCAGCTGCGGGCCCGGTACGACCGGTTCGAGGGCGACCTCGACCGGGACGCGGCGCAGGACGCCT
CCGCCGCCGCCCGCACCCGCTTCGGCCGCGCGCTGAAGCGCTACCTGAACCGCCGCGAGCTGGACATCGACTGGGAGACC
GCCAGCAGCGCCCCGCTGGAGGCCCTGGTCAACAGCCTGTGCATGGGCCTGCCCTTCGAACCGGCCGAGAAGCAGGCGCT
GCTGGAGGCCGAGGGGCTGATGGGCCGGTTCGAGACCCTGATCGCCCTGCTGGAGATCGACGCCTCCGAGCCGGATGACG
ACACCCAGTCGGTGCAGTAG

Upstream 100 bases:

>100_bases
CTCCTCACCATCTTCGAGGCCGCGGGTCCGACCTCGGAGGTCGCCAAGCAGGGCCGGCGCAAGCTCTCCTCCCTGCTGTT
CAGCTAGGGAGGCGGGCGCC

Downstream 100 bases:

>100_bases
AGGGAAGGCATGGAAGACGCCCTGCCCGCCCTCGATGTCGACGTCGATCCGCGCCTGCTGGAGATCCTGGTCTGTCCGCT
GACCCGCGGGCCCCTGGAGT

Product: ATP-dependent protease La domain protein

Products: NA

Alternate protein names: ATP-dependent protease La 2 [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAAYRRAADLPQVIPVFPLDGALLLPGGDLPLQIFEPRYLNMIDDVMGGDRIIGMIQSKPGGDRTRPKLADVGCAGRITS
YAETSDGRYLITLTGICRFEAGEELILRTPYRQLRARYDRFEGDLDRDAAQDASAAARTRFGRALKRYLNRRELDIDWET
ASSAPLEALVNSLCMGLPFEPAEKQALLEAEGLMGRFETLIALLEIDASEPDDDTQSVQ

Sequences:

>Translated_219_residues
MAAYRRAADLPQVIPVFPLDGALLLPGGDLPLQIFEPRYLNMIDDVMGGDRIIGMIQSKPGGDRTRPKLADVGCAGRITS
YAETSDGRYLITLTGICRFEAGEELILRTPYRQLRARYDRFEGDLDRDAAQDASAAARTRFGRALKRYLNRRELDIDWET
ASSAPLEALVNSLCMGLPFEPAEKQALLEAEGLMGRFETLIALLEIDASEPDDDTQSVQ
>Mature_218_residues
AAYRRAADLPQVIPVFPLDGALLLPGGDLPLQIFEPRYLNMIDDVMGGDRIIGMIQSKPGGDRTRPKLADVGCAGRITSY
AETSDGRYLITLTGICRFEAGEELILRTPYRQLRARYDRFEGDLDRDAAQDASAAARTRFGRALKRYLNRRELDIDWETA
SSAPLEALVNSLCMGLPFEPAEKQALLEAEGLMGRFETLIALLEIDASEPDDDTQSVQ

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG2802

COG function: function code R; Uncharacterized protein, similar to the N-terminal domain of Lon protease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 24253; Mature: 24122

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAYRRAADLPQVIPVFPLDGALLLPGGDLPLQIFEPRYLNMIDDVMGGDRIIGMIQSKP
CCCCHHHCCCCCCCEEECCCCEEECCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEECCC
GGDRTRPKLADVGCAGRITSYAETSDGRYLITLTGICRFEAGEELILRTPYRQLRARYDR
CCCCCCCHHHCCCCCCCCCCCEECCCCEEEEEEECEEEECCCCCEEEECCHHHHHHHHHH
FEGDLDRDAAQDASAAARTRFGRALKRYLNRRELDIDWETASSAPLEALVNSLCMGLPFE
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
PAEKQALLEAEGLMGRFETLIALLEIDASEPDDDTQSVQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAYRRAADLPQVIPVFPLDGALLLPGGDLPLQIFEPRYLNMIDDVMGGDRIIGMIQSKP
CCCHHHCCCCCCCEEECCCCEEECCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEECCC
GGDRTRPKLADVGCAGRITSYAETSDGRYLITLTGICRFEAGEELILRTPYRQLRARYDR
CCCCCCCHHHCCCCCCCCCCCEECCCCEEEEEEECEEEECCCCCEEEECCHHHHHHHHHH
FEGDLDRDAAQDASAAARTRFGRALKRYLNRRELDIDWETASSAPLEALVNSLCMGLPFE
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
PAEKQALLEAEGLMGRFETLIALLEIDASEPDDDTQSVQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8331083; 8331082 [H]