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The map label for this gene is aroD [H]

Identifier: 195977992

GI number: 195977992

Start: 906662

End: 907342

Strand: Direct

Name: aroD [H]

Synonym: Sez_0864

Alternate gene names: 195977992

Gene position: 906662-907342 (Clockwise)

Preceding gene: 195977991

Following gene: 195977993

Centisome position: 44.79

GC content: 41.26

Gene sequence:

>681_bases
ATGAAAATTGTAGCACCAGTCATGCCAAGAAATGTTGAAGAGGCTCAATCTATCGACGTTTCTAAATATCAAGATGTTAA
TTTAATCGAGTGGCGAGCAGACTTTCTTCCTAAGGAGGATATTGTTTCTGTAGCGCCAGCTATTTTTGAAAAATTTGCAG
GTAGAGAGATTATTTTTACCCTTCGTACAAGTCGAGAAGGAGGGCATATTACACTTTCTGATCAGGAATACGTTGATTTG
ATCAAGGAGATCAATGCGATTTATAATCCTGACTATATTGACTTTGAATACTTTAGTCACAAGGCTGTCTTTCATGAAAT
GCTTGACTTTCCGAATCTTGTCTTGTCTTATCACAATTTTGATGAGACGCCTGAAAATCTGATGGAGGCTTTTTCGGAGA
TGACTAAGCTAGCTCCTCGCGTTGTCAAGATTGCTGTCATGCCGCAGAGCGAGCAGGACGTTTTGGATTTGATGAATTAT
ACCAGAGGCTTTAAAACACTTAACCCAGAGCAGGAATTTGCAACCATGTCAATGGGAAAGCTAGGCAGACTATCACGCTT
GGCAGGTGATGTTGTAGGGTCCTCGTGGACTTTTGTGTCCTTAGATCAAGCCAGTGCACCAGGGCAGGTTTCCTTGGCTG
ATATGAAAAGGATTCTTCATGTTTTGGAATCTGAGGATTGA

Upstream 100 bases:

>100_bases
TAGCTCAGATGACACTTGAGCAGCTTCCAAGTGATTTTACTATCAATAAAGCAGATGAAAGAAGTAATTATTTAAAGGTA
TTTACTATAAGGGTACGAGA

Downstream 100 bases:

>100_bases
TAAGATACGGTAACAGACATTATTCTCTTGGATAGCTTAGAATAATGTCTTTTAGTTGTCTAGAGGAGGGCAGGTTTGCT
TTTTATGTCTATGATTGATA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSVAPAIFEKFAGREIIFTLRTSREGGHITLSDQEYVDL
IKEINAIYNPDYIDFEYFSHKAVFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRILHVLESED

Sequences:

>Translated_226_residues
MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSVAPAIFEKFAGREIIFTLRTSREGGHITLSDQEYVDL
IKEINAIYNPDYIDFEYFSHKAVFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRILHVLESED
>Mature_226_residues
MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSVAPAIFEKFAGREIIFTLRTSREGGHITLSDQEYVDL
IKEINAIYNPDYIDFEYFSHKAVFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRILHVLESED

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=233, Percent_Identity=31.7596566523605, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 25732; Mature: 25732

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSVAPAIFEKFAGREIIFT
CCCCCCCCCCCHHHHHCCCCHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHCCCEEEEE
LRTSREGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKAVFHEMLDFPNLVLSYHNF
EEECCCCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCC
DETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNYTRGFKTLNPEQEFATMSMGK
CCCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRILHVLESED
HHHHHHHHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSVAPAIFEKFAGREIIFT
CCCCCCCCCCCHHHHHCCCCHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHCCCEEEEE
LRTSREGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKAVFHEMLDFPNLVLSYHNF
EEECCCCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCC
DETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNYTRGFKTLNPEQEFATMSMGK
CCCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRILHVLESED
HHHHHHHHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA