Click here to switch to the map view.

The map label for this gene is aroC [H]

Identifier: 195977993

GI number: 195977993

Start: 907455

End: 908621

Strand: Direct

Name: aroC [H]

Synonym: Sez_0865

Alternate gene names: 195977993

Gene position: 907455-908621 (Clockwise)

Preceding gene: 195977992

Following gene: 195977994

Centisome position: 44.83

GC content: 46.44

Gene sequence:

>1167_bases
ATGAGGTATTTAACAGCAGGTGAGTCACATGGACAAGCTTTGACGGCCATTATAGAGGGAATTCCTGCAGGCTTAGCATT
ATCAGCTGAGCTTATTAACAAGGAACTGAAGCGTCGGCAGGGGGGATATGGTCGTGGCGCACGCATGCGCATTGAATCAG
ATCGTGTGCATATCTCTTCAGGTGTTCGTCATGGCAAAACAACAGGAGCACCAATTACTTTAACCATTCAAAACAAGGAC
CATCAAAAATGGCTAGACATTATGGCTGTTGAGGCTGTTGAAGAGCAAATCAAGTTCAAGCGTAAAATCACTCGTCCACG
CCCTGGTCATGCTGACTTGGTTGGGGGGATCAAATATCGTTTTGATGATTTAAGAAATGCGCTTGAGCGCTCCTCTGCCA
GAGAAACAGCGATGCGTGTGGCCGTTGGTGCAATTGCTAAGGCAGTCCTTACTGAGCTTGGGATCGAAACTGCTAATCAC
GTCCTGGTTTTTGGTGGTATTGAGGTAGCTGTGCCTGAGGCGATGCCTTTTACAGACATCAAAAAAGCAGCAGAGGCTTC
TGATTTATCTATTGTCAATCCTAAGCAGGAGGCGACTATCAAGGCTCATATTGATCAAGTCAAAAAAGAGGGGGATACGC
TTGGCGGTATTATTGAAACAATCATTTATGGCTTACCAGCAGGCTTAGGCTCATACGTTCAATGGGATCGCAAATTAGAT
GCCAAAATCGCGCAGACTGTCCTGTCTATCAACGCCTTTAAAGGGGTCGAATTTGGTATGGGCTTTGACATGGGTTACCA
AAAAGGCTCGCAGGTCATGGACGACATCATTTGGCATGAGACAAGCGGCTACAGTCGTCGAACAAACCGACTAGGTGGCT
TTGAGGCAGGTATGACTACTGGTCAGCCTATTGTTGTCAAAGGGGTGATGAAGCCGATTCCCACCCTCTACAAGCCCCTA
ATGTCTGTGGATACTGAGACGCACGAGCCTTACAAGGCTACTGTTGAGCGTTCTGATCCTACGGCTCTGCCGGCTGCCGG
TGTCGTGATGGAAAATGTTGTAGCAACTGTCATCACAAAAGAGATTTTGGAACAATTTCCATCAGACAATATGACCGATT
TAAAGCAGGCTTTTTTTGCCTATCGTGACTATGTTCATCATTTTTAA

Upstream 100 bases:

>100_bases
ACAGACATTATTCTCTTGGATAGCTTAGAATAATGTCTTTTAGTTGTCTAGAGGAGGGCAGGTTTGCTTTTTATGTCTAT
GATTGATAAATGGAGGAATA

Downstream 100 bases:

>100_bases
GCGACAAATGGCTTGATATTGTGATATGATAAGGATAATAAATGATAAAAGGAGATCCAGATGTCCCAAGATATTTATGA
TTATGCCAATAAGCTTGAGC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYGRGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKD
HQKWLDIMAVEAVEEQIKFKRKITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAVLTELGIETANH
VLVFGGIEVAVPEAMPFTDIKKAAEASDLSIVNPKQEATIKAHIDQVKKEGDTLGGIIETIIYGLPAGLGSYVQWDRKLD
AKIAQTVLSINAFKGVEFGMGFDMGYQKGSQVMDDIIWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPL
MSVDTETHEPYKATVERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF

Sequences:

>Translated_388_residues
MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYGRGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKD
HQKWLDIMAVEAVEEQIKFKRKITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAVLTELGIETANH
VLVFGGIEVAVPEAMPFTDIKKAAEASDLSIVNPKQEATIKAHIDQVKKEGDTLGGIIETIIYGLPAGLGSYVQWDRKLD
AKIAQTVLSINAFKGVEFGMGFDMGYQKGSQVMDDIIWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPL
MSVDTETHEPYKATVERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF
>Mature_388_residues
MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYGRGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKD
HQKWLDIMAVEAVEEQIKFKRKITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAVLTELGIETANH
VLVFGGIEVAVPEAMPFTDIKKAAEASDLSIVNPKQEATIKAHIDQVKKEGDTLGGIIETIIYGLPAGLGSYVQWDRKLD
AKIAQTVLSINAFKGVEFGMGFDMGYQKGSQVMDDIIWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPL
MSVDTETHEPYKATVERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=368, Percent_Identity=37.5, Blast_Score=169, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6321290, Length=374, Percent_Identity=31.283422459893, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 42573; Mature: 42573

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYGRGARMRIESDRVHISS
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEECC
GVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRKITRPRPGHADLVGGIKYR
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHH
FDDLRNALERSSARETAMRVAVGAIAKAVLTELGIETANHVLVFGGIEVAVPEAMPFTDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCEEEECCEEEECCCCCCHHHH
KKAAEASDLSIVNPKQEATIKAHIDQVKKEGDTLGGIIETIIYGLPAGLGSYVQWDRKLD
HHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AKIAQTVLSINAFKGVEFGMGFDMGYQKGSQVMDDIIWHETSGYSRRTNRLGGFEAGMTT
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCC
GQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKATVERSDPTALPAAGVVMENVVATVITK
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
EILEQFPSDNMTDLKQAFFAYRDYVHHF
HHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYGRGARMRIESDRVHISS
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEECC
GVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRKITRPRPGHADLVGGIKYR
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHH
FDDLRNALERSSARETAMRVAVGAIAKAVLTELGIETANHVLVFGGIEVAVPEAMPFTDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCEEEECCEEEECCCCCCHHHH
KKAAEASDLSIVNPKQEATIKAHIDQVKKEGDTLGGIIETIIYGLPAGLGSYVQWDRKLD
HHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AKIAQTVLSINAFKGVEFGMGFDMGYQKGSQVMDDIIWHETSGYSRRTNRLGGFEAGMTT
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCC
GQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKATVERSDPTALPAAGVVMENVVATVITK
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
EILEQFPSDNMTDLKQAFFAYRDYVHHF
HHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA