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The map label for this gene is msrR [H]

Identifier: 195977834

GI number: 195977834

Start: 729369

End: 730799

Strand: Direct

Name: msrR [H]

Synonym: Sez_0702

Alternate gene names: 195977834

Gene position: 729369-730799 (Clockwise)

Preceding gene: 195977833

Following gene: 195977835

Centisome position: 36.03

GC content: 42.21

Gene sequence:

>1431_bases
ATGACGAGATACCAAAAGGGTGGTCTAAGCCACCACGAAGAATTACGATATTTTTATTTATTAAGAAATTTAAATTATTT
GACTGAGACTGAACGCAGAGAATTTACCTTTTTAAAGTCAAAGATGGAGTCAAGGGCTATGCCTTCTCGTTCTCAGCGCT
CCTTGACTCATTATACTAGGGGTGGGCGTGACGATTATGCTCAAGCTTCACAGGATAATGCTGATGCTTATGATATGAGT
GATGAGCAACAGGCTGGACCTAATGGCCTGCCTCTTTATCCGAGATCAGAAAGACGTAGCAAAAGGCATCAGCAAAAGCC
AATACTAGCCCCTCAGCAGGACTTCTATGATGACCCAGATCAGGCGATCTATGAGGAGCTTGCGCCTGAGGCTATGCCTA
AAAAGGGTAGAACGAAAAAAAAGAAGGGACGTCTGAGACGTTTTTTCAGAGTACTCTTTTTCTTGTTGCTGCTGCTTGTT
GCAGGGATAGCTTTCATGTTTTTCAAGGGAATGATGGACGTGTCTACTAACAAGGCCAATTATAAGCCAGCAGTTTCGCA
GGTCTTTCATGGTCAGGATACTAGCGATGGCACTAATATTTTAATTCTAGGCTCAGACCAGAGGATTACGCAAGGCTCAA
CAGATGCTCGAACAGATACAATCATGGTGGTTAATGTTGGCAATAAGGAGAATAAAATCAAAATGGTCTCCTTCATGAGA
GATACCTTGGTTAATATTCCTGGCTATAGCTATAATAATCAGGATTCCTATGATTTAAAATTGAACGCCTCCTTTAATTT
AGGAGAGCAGGAAAATCATCAAGGAGCAGAATTTGTGCGTCAGACACTCAAGCATAATTTTGATATTGACATTAAATATT
ATGTCATGGTTGACTTTGAAACCTTTGCTGAGGCTATTGACACACTGTTTCCAGATGGTGTTACCATTGATGCCAAATTT
GCTACTGTAAATGGCGAAGCAGTCGCTGCTGTTGATGTACCAGATGATTTACGAATGAAAGACGGAGTGGTTCCCAACCA
AACCATAACGGTTGGTGAGCAAAAAATGGATGGTCGTACCCTGCTCAACTATGCTCGCTTCCGAAAGGACGATGAGGGTG
ATTTTGGTCGGACCGTACGTCAGCAGCAGGTGATGGCTGCTATCATGTCTCAAATCAAGGATCCAACCAAGCTCTTTACG
GGCTCAGCAGCTATTGGTAAGATTTATGCCCTAACCTCAACCAATGTCTCCTTCCCATTTGTCCTTAAAAATGGAGTGTC
CGTCTTGACTAATGGCAAAAACGGTGTGGAGCATGTGACGATTCCTGAAAATGGGGATTGGATTGATGAATATGACATGT
ATGGTGGTCAGGCTCTCTTTATTGATTTTGCTAAGTATCAAAATCGATTATCTAAGCTGGGATTACGCTAA

Upstream 100 bases:

>100_bases
TAACGAATTTTAGAGGACAATCTCGTTAATATAGGTTATAATAGAATCATTAGACAAAGAATAGAAGAAATTGTATTAGA
ATACTAAGAGTTGGAAGAGC

Downstream 100 bases:

>100_bases
GATATGCTATAATGAAGGGTAACGATGGTTGCTCTTCTTTTTTGAGTGATTAGTGTAGTAAAAGAAAAGGAAAGTAAATG
TTAAGTAAAAACGATATTGT

Product: Putative PBP 5 synthesis repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMESRAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMS
DEQQAGPNGLPLYPRSERRSKRHQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRTKKKKGRLRRFFRVLFFLLLLLV
AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDARTDTIMVVNVGNKENKIKMVSFMR
DTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGAEFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKF
ATVNGEAVAAVDVPDDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQIKDPTKLFT
GSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDEYDMYGGQALFIDFAKYQNRLSKLGLR

Sequences:

>Translated_476_residues
MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMESRAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMS
DEQQAGPNGLPLYPRSERRSKRHQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRTKKKKGRLRRFFRVLFFLLLLLV
AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDARTDTIMVVNVGNKENKIKMVSFMR
DTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGAEFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKF
ATVNGEAVAAVDVPDDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQIKDPTKLFT
GSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDEYDMYGGQALFIDFAKYQNRLSKLGLR
>Mature_475_residues
TRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMESRAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSD
EQQAGPNGLPLYPRSERRSKRHQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRTKKKKGRLRRFFRVLFFLLLLLVA
GIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDARTDTIMVVNVGNKENKIKMVSFMRD
TLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGAEFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFA
TVNGEAVAAVDVPDDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQIKDPTKLFTG
SAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDEYDMYGGQALFIDFAKYQNRLSKLGLR

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 54144; Mature: 54013

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMESRAMPSRSQRSLTHYTR
CCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKRHQQKPILAPQQDFYDDPD
CCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCCHH
QAIYEELAPEAMPKKGRTKKKKGRLRRFFRVLFFLLLLLVAGIAFMFFKGMMDVSTNKAN
HHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDARTDTIMVVNVGNKENKIKMVSFMR
CCHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHH
DTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGAEFVRQTLKHNFDIDIKYYVMVDFE
HHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEHH
TFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVPDDLRMKDGVVPNQTITVGEQKMDGRT
HHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCCCHHHCCCCCCCEEEECCCCCCCHH
LLNYARFRKDDEGDFGRTVRQQQVMAAIMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPF
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHCEEEEEEECCCCCCE
VLKNGVSVLTNGKNGVEHVTIPENGDWIDEYDMYGGQALFIDFAKYQNRLSKLGLR
EECCCCEEEECCCCCCEEEECCCCCCCCHHHHCCCCEEEEEEHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMESRAMPSRSQRSLTHYTR
CCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKRHQQKPILAPQQDFYDDPD
CCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCCHH
QAIYEELAPEAMPKKGRTKKKKGRLRRFFRVLFFLLLLLVAGIAFMFFKGMMDVSTNKAN
HHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDARTDTIMVVNVGNKENKIKMVSFMR
CCHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHH
DTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGAEFVRQTLKHNFDIDIKYYVMVDFE
HHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEHH
TFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVPDDLRMKDGVVPNQTITVGEQKMDGRT
HHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCCCHHHCCCCCCCEEEECCCCCCCHH
LLNYARFRKDDEGDFGRTVRQQQVMAAIMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPF
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHCEEEEEEECCCCCCE
VLKNGVSVLTNGKNGVEHVTIPENGDWIDEYDMYGGQALFIDFAKYQNRLSKLGLR
EECCCCEEEECCCCCCEEEECCCCCCCCHHHHCCCCEEEEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]