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The map label for this gene is holA [H]

Identifier: 195977789

GI number: 195977789

Start: 676518

End: 677579

Strand: Direct

Name: holA [H]

Synonym: Sez_0653

Alternate gene names: 195977789

Gene position: 676518-677579 (Clockwise)

Preceding gene: 195977788

Following gene: 195977790

Centisome position: 33.42

GC content: 41.34

Gene sequence:

>1062_bases
ATGATTGCGATAGAAAAGATAGATGCCTTAAGCAAAGAAAGCTTAGGCTTGATTACGGTTGTAGCTGGTGAGGATATTGG
GCAATATAGCCATATGAAGGCGCTGCTACTAAAAAAAATAGCCTTTGATCCGTCTGACTTGACCTATTCTTATTTTGATA
TGTCTGAGGCTTTGTATCAAACAGCTGAGATGGACCTTGTGAGCATGCCCTTTTTTGCTGACCAAAAGGTGGTTATTTTG
GATCATCTGCTGGATATTACCACCAGTAAAAAAAGCTACCTAAAGGAAAAAGAGCTAAAGGCATTTGAGGACTATTTGGA
AAATCCTGTAGAGACCACACGTTTGGTTATCTTTGCACCAGGAAAGCTTGATGGTAAGCGTCGTTTGGTCAAGATTCTCA
AGCGTGATGCCCTTATTTTTGAAGCTAGTCCTTTGAAGGCTGCTGAAAAAAGAACCTATTTTCAAAAATACAGTCACCAG
CTGGACTTGAGCTTTGCTAGTGGTGCTTTTGATCAATTGCTGCTGAAGTCAAATGATGATTTTAGTCAAATCATGAAGAA
TATGACCTTCTTGAAGGCCTATAAAAAAAGTGGTCCTATCACAGTAGAGGACATTGCTCAAGCGATTCCCAAGAGCTTGC
AGGATAATGTCTTTGACTTGACAAGATTGGTGTTACAAGGAAAGATTGATGCTGCTCGGGAGCTGGTTCATGATTTGCGC
CTATCTGGCGAGGACGATATTAAGCTTATTGCCATTATGCTGGGGCAGTTTCGTCTGTTTTTGCAGCTGGCAACCTTGGT
GCGGTCTGGAAAAACAGAACAGCAGCTAGTCACTAGCCTATCAGACCTGTTAGGCAGACGTGTTAATCCCTATCAGGTGA
AATATGCACTCAAGGATTCTAGAGCCTTGTCTCTCTCTTATTTGCAGCTGGCTGTAAAGACCTTAATTGAAACAGATTAT
CACATTAAAACAGGTGTTTACACAAAGGATTATCTTTTTGACCTTGCTCTCTTAAAGCTAGTAGCGCATTCTCAGGGAAA
TACTGACCTCTCAGACCTATGA

Upstream 100 bases:

>100_bases
AGAGCTATATGCAAGGGCCTAGGTCTGGCAGTGAAGTAGAGAATGAAAAAGATCAGCTTTAGCAAGGTCATATTTAGTAA
GAAAATGCTATAATAAAACC

Downstream 100 bases:

>100_bases
GCATCAATCAAATTAGTTGAAAGCCTCTATTTTTTGAGATAAGATAGACTTATCATAAAGGAAAAGAGGAAAGAGACATG
ACCATTATATTACCGGATCT

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIAIEKIDALSKESLGLITVVAGEDIGQYSHMKALLLKKIAFDPSDLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIL
DHLLDITTSKKSYLKEKELKAFEDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVFDLTRLVLQGKIDAARELVHDLR
LSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQLVTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDY
HIKTGVYTKDYLFDLALLKLVAHSQGNTDLSDL

Sequences:

>Translated_353_residues
MIAIEKIDALSKESLGLITVVAGEDIGQYSHMKALLLKKIAFDPSDLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIL
DHLLDITTSKKSYLKEKELKAFEDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVFDLTRLVLQGKIDAARELVHDLR
LSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQLVTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDY
HIKTGVYTKDYLFDLALLKLVAHSQGNTDLSDL
>Mature_353_residues
MIAIEKIDALSKESLGLITVVAGEDIGQYSHMKALLLKKIAFDPSDLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIL
DHLLDITTSKKSYLKEKELKAFEDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVFDLTRLVLQGKIDAARELVHDLR
LSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQLVTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDY
HIKTGVYTKDYLFDLALLKLVAHSQGNTDLSDL

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 39925; Mature: 39925

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAIEKIDALSKESLGLITVVAGEDIGQYSHMKALLLKKIAFDPSDLTYSYFDMSEALYQ
CCCHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
TAEMDLVSMPFFADQKVVILDHLLDITTSKKSYLKEKELKAFEDYLENPVETTRLVIFAP
HHHCCHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
GKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQLDLSFASGAFDQLLLKSNDD
CCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHCCCCC
FSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVFDLTRLVLQGKIDAARELVHDLR
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQLVTSLSDLLGRRVNPYQVKYALKDS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
RALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFDLALLKLVAHSQGNTDLSDL
CHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIAIEKIDALSKESLGLITVVAGEDIGQYSHMKALLLKKIAFDPSDLTYSYFDMSEALYQ
CCCHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
TAEMDLVSMPFFADQKVVILDHLLDITTSKKSYLKEKELKAFEDYLENPVETTRLVIFAP
HHHCCHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
GKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQLDLSFASGAFDQLLLKSNDD
CCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHCCCCC
FSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVFDLTRLVLQGKIDAARELVHDLR
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQLVTSLSDLLGRRVNPYQVKYALKDS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
RALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFDLALLKLVAHSQGNTDLSDL
CHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]