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The map label for this gene is pncA [H]

Identifier: 195977531

GI number: 195977531

Start: 416842

End: 417399

Strand: Direct

Name: pncA [H]

Synonym: Sez_0388

Alternate gene names: 195977531

Gene position: 416842-417399 (Clockwise)

Preceding gene: 195977530

Following gene: 195977532

Centisome position: 20.59

GC content: 49.46

Gene sequence:

>558_bases
GTGAAGGCCTTGATTTCTATTGATTATACGAATGACTTTGTAGCTGATGATGGTAGCCTGACGGCAGGAGCACCTGCTCA
GGTGATTTCAGAGGCGATGGCTAGCGTTGTTGAGGCTGCCTTTGAGGCCGGCTACTATATCTTTTTTGCGATTGATGCCC
ACGAGGAGGGAGATAGCTTTCACCCGGAGGCAGCCTTGTTTCCACCGCATAATATTATCGGGACAAGGGGTCGGGACCTG
TATGGTCCTTTGATGACCGTCTATAGCAAATACCAGCAGGATCAGCGGGTCTTTTGGCTGGATAAGCGGCATTATTCTGC
CTTTTCGGGGACTGATTTGGATATTCGTCTTCGTGAGCGTGGCGTCACGACGCTGGTCTTGACAGGTGTGCTGACGGATA
TTTGTGTCCTTCATACAGCGATTGATGCCTATAAATTGGGCTACAAGCTTGAGATTATCACATCAGCAGTGGCGAGCAAT
TCAAGAGAAAATCACCAGTGGGCGCTGAACCACTGTAGGACTGTCCTAGGAGCAAAGCTTCTTGATCGGCTTTCTTAG

Upstream 100 bases:

>100_bases
ATAAGTGTCTAATCATACTGAATATTAAAAGCAGGCTTAGTTCTTATGGCTTGCTGTCATGCAGCTAAGAGAGCATAAGC
TTTTTGGGGAGGGATAAGCT

Downstream 100 bases:

>100_bases
GTGATTGTTTGATCAGCTGGGGCAGCTGATCAAGTAAGGTAGTATTAGCTGCTGCTTGGCTCAGCACTGATCTTAAGGGC
TTTCTAGTCAGATCCTTTGG

Product: pyrazinamidase/nicotinamidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAGYYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDL
YGPLMTVYSKYQQDQRVFWLDKRHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
SRENHQWALNHCRTVLGAKLLDRLS

Sequences:

>Translated_185_residues
MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAGYYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDL
YGPLMTVYSKYQQDQRVFWLDKRHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
SRENHQWALNHCRTVLGAKLLDRLS
>Mature_185_residues
MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAGYYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDL
YGPLMTVYSKYQQDQRVFWLDKRHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
SRENHQWALNHCRTVLGAKLLDRLS

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

Organism=Escherichia coli, GI87081992, Length=70, Percent_Identity=45.7142857142857, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 20530; Mature: 20530

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAGYYIFFAIDAHEEGDSF
CCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCC
HPEAALFPPHNIIGTRGRDLYGPLMTVYSKYQQDQRVFWLDKRHYSAFSGTDLDIRLRER
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCC
GVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASNSRENHQWALNHCRTVLGAKL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LDRLS
HHHCC
>Mature Secondary Structure
MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAGYYIFFAIDAHEEGDSF
CCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCC
HPEAALFPPHNIIGTRGRDLYGPLMTVYSKYQQDQRVFWLDKRHYSAFSGTDLDIRLRER
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCC
GVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASNSRENHQWALNHCRTVLGAKL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LDRLS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]