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The map label for this gene is pdxJ

Identifier: 195953021

GI number: 195953021

Start: 580594

End: 581316

Strand: Direct

Name: pdxJ

Synonym: HY04AAS1_0646

Alternate gene names: 195953021

Gene position: 580594-581316 (Clockwise)

Preceding gene: 195953020

Following gene: 195953022

Centisome position: 37.23

GC content: 37.21

Gene sequence:

>723_bases
ATGAGACTGGGCGTAAATATAGATCATGTTGCTACCATCAGAGAAGCGAGAAAAACCTTCGAACCATCTGTATTAGAAGC
TGCTTTTATAGCAAAAAGAGCTGGCGCTCACCAAATCACAATGCATTTAAGAGAAGATAGAAGACACATAAAAGATGAAG
ATGTAAGACTGGTGAGGACTTCGGTGGAAATTCCACTGAACCTTGAAATGGCACCTACGCAAGAAATAAAAACTATCGCA
TTAGAAATAAAGCCTCAAAGAGTTACGCTTGTACCAGAAAAAAGACAAGAAGTAACCACCGAAGGAGGGCTAGACATATT
ATCAAACGCAGATTATTTAAAGAACTATATAAAGGATTTTAAAGAAAATCAGATAGAGGTGTCTTTTTTTATAGACCCAG
ACCTTGGGCAAGTAGAAGCATCGAAATTTACGGGCGCAGATGCAATAGAACTGCATACTGGAAGATTTGCAGAGAGTTTT
CATAAGAGAGATTTTAGGCTTTTAGAAGAAGAAAAAAATAGGCTAAGAAAAGCTGCAACCTTAGCAAGAGAACTAGGTTT
GAATGTTTACGCAGGGCACGGCATCACTTATCAAAATATACATCTTATATTGGATTTAAAAGGGCTTATAGAAGAGCTTA
ACATAGGACATTCTATAATATCAAATGCGGTGCTGTTTGGCTTGGAGAAAGCGATCACAAAAATGCTTGGTATAATATCA
TGA

Upstream 100 bases:

>100_bases
CATGTGATGAGGAGAATAATACAAGAAGTAAAAGGTATTAATAGAGTGGTTTACGATATATCTTCAAAACCACCAGCCAC
AATAGAGTGGGAATAGTGTT

Downstream 100 bases:

>100_bases
GCGATTATTCTAAAAAGAGGGATTTTTCAAAAACACCAGAACCTCGATGGAGTGTAATAGAAAGCCACGAATCTATATTT
GTAATACAAGAACATCATGC

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRLGVNIDHVATIREARKTFEPSVLEAAFIAKRAGAHQITMHLREDRRHIKDEDVRLVRTSVEIPLNLEMAPTQEIKTIA
LEIKPQRVTLVPEKRQEVTTEGGLDILSNADYLKNYIKDFKENQIEVSFFIDPDLGQVEASKFTGADAIELHTGRFAESF
HKRDFRLLEEEKNRLRKAATLARELGLNVYAGHGITYQNIHLILDLKGLIEELNIGHSIISNAVLFGLEKAITKMLGIIS

Sequences:

>Translated_240_residues
MRLGVNIDHVATIREARKTFEPSVLEAAFIAKRAGAHQITMHLREDRRHIKDEDVRLVRTSVEIPLNLEMAPTQEIKTIA
LEIKPQRVTLVPEKRQEVTTEGGLDILSNADYLKNYIKDFKENQIEVSFFIDPDLGQVEASKFTGADAIELHTGRFAESF
HKRDFRLLEEEKNRLRKAATLARELGLNVYAGHGITYQNIHLILDLKGLIEELNIGHSIISNAVLFGLEKAITKMLGIIS
>Mature_240_residues
MRLGVNIDHVATIREARKTFEPSVLEAAFIAKRAGAHQITMHLREDRRHIKDEDVRLVRTSVEIPLNLEMAPTQEIKTIA
LEIKPQRVTLVPEKRQEVTTEGGLDILSNADYLKNYIKDFKENQIEVSFFIDPDLGQVEASKFTGADAIELHTGRFAESF
HKRDFRLLEEEKNRLRKAATLARELGLNVYAGHGITYQNIHLILDLKGLIEELNIGHSIISNAVLFGLEKAITKMLGIIS

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=233, Percent_Identity=51.5021459227468, Blast_Score=226, Evalue=9e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_HYDS0 (B4U872)

Other databases:

- EMBL:   CP001130
- RefSeq:   YP_002121311.1
- ProteinModelPortal:   B4U872
- SMR:   B4U872
- GeneID:   6743446
- GenomeReviews:   CP001130_GR
- KEGG:   hya:HY04AAS1_0646
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 27188; Mature: 27188

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: ACT_SITE 42-42 ACT_SITE 69-69 ACT_SITE 193-193 BINDING 6-6 BINDING 17-17 BINDING 44-44 BINDING 49-49 BINDING 99-99 BINDING 194-194

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGVNIDHVATIREARKTFEPSVLEAAFIAKRAGAHQITMHLREDRRHIKDEDVRLVRT
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEE
SVEIPLNLEMAPTQEIKTIALEIKPQRVTLVPEKRQEVTTEGGLDILSNADYLKNYIKDF
EECCCEEEECCCCHHEEEEEEEECCCEEEECCCHHHHHCCCCCCHHHCCCHHHHHHHHHH
KENQIEVSFFIDPDLGQVEASKFTGADAIELHTGRFAESFHKRDFRLLEEEKNRLRKAAT
HCCCEEEEEEECCCCCCEEHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LARELGLNVYAGHGITYQNIHLILDLKGLIEELNIGHSIISNAVLFGLEKAITKMLGIIS
HHHHHCCEEEECCCCEEEEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLGVNIDHVATIREARKTFEPSVLEAAFIAKRAGAHQITMHLREDRRHIKDEDVRLVRT
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEE
SVEIPLNLEMAPTQEIKTIALEIKPQRVTLVPEKRQEVTTEGGLDILSNADYLKNYIKDF
EECCCEEEECCCCHHEEEEEEEECCCEEEECCCHHHHHCCCCCCHHHCCCHHHHHHHHHH
KENQIEVSFFIDPDLGQVEASKFTGADAIELHTGRFAESFHKRDFRLLEEEKNRLRKAAT
HCCCEEEEEEECCCCCCEEHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LARELGLNVYAGHGITYQNIHLILDLKGLIEELNIGHSIISNAVLFGLEKAITKMLGIIS
HHHHHCCEEEECCCCEEEEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA