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The map label for this gene is cfa [H]

Identifier: 195952955

GI number: 195952955

Start: 517921

End: 519132

Strand: Direct

Name: cfa [H]

Synonym: HY04AAS1_0580

Alternate gene names: 195952955

Gene position: 517921-519132 (Clockwise)

Preceding gene: 195952954

Following gene: 195952956

Centisome position: 33.21

GC content: 34.57

Gene sequence:

>1212_bases
ATGTTAGAATCTTTAATTCAGGAGGTTAGTAAAAAGTTAGAAGAAGGACTATGCGTCGAGCTTCCAGACGGTAGAGTTCT
CGGTAGTGGTAATTGCAAAGTTAAAGTCAAAGATAAGAATGTTATATTAAACATACTAAAAGATCCTGAAATGGGCTTTG
GAGAGGCATATATGAAAGGAGCCATAGAGATAGATGGAGATATTGAGAGATTTTTAGTGGCCTGCCTTAATTATCTTGAA
GAAAATAAACAAGAGAAAAATTTTAGAAATAGTTTATTTAGAAATATTCTTAAATATACCGGACTTCTGAAGTTTACTGA
GGAAAAGGAAGTAAGAAGTCATTATGATCTTGGCAACGACTTTTATAAGCTTTGGCTTGATGATTCTATGACATATTCTT
GTGCTTTTTTTACAGATGCACATCAGAGTTTAGAGATGGCGCAAAAGGAAAAAAGGAAGATTATATATGGGAAACTGCAA
CTTACCGATGGGGATAAATTATTGGATATAGGCTGTGGTTGGGGTGCCATAATTCTTGAAGTATCAAAACTATACAACAT
AGAAGCTGTAGGTATAACGGTTTCAAAAAACCAATACGATTATGTAAAATCAAAGATAGAAAACAATGGACTAAGTAGTA
GAACAAGAGTTTATCTAATGCACTATGAAGATCTACCAAGCCTTGGAGAGAAGTTTAACAAAATAGTTTCGGTAGGTATG
TTTGAGCATGTAGGTAAAGGAAGACATAAAGACTTCTTTAAAATAGTACACAATACTATTGAAGAAAAAGGCCTTTTCCT
CCTTCACACCATAGGAAAGGTTTTGCCAGAAAGCCAGAGCAAGTGGATAAGAAAGTACATATTTCCCGGAGGATATTTAC
CTGCACTTACCGAAATAATCGAAGCAACCAAAGGGTCAGAATTCAACCTTATAGATATAGATGATTGGAGACTCCATTAT
TACAAGACGCTTCAAGAGTGGAGAAAAAGATTTTATAAGCATGCCGAAGAAGTTGTGAAAAAAAATGGCGAGGAGTTCTT
CCGCATGTGGGACCTTTACTTAATAGGTTCTGCGGTATCGTTCCTGACCGGTTCCAATCATCTTTTTCAAATTCTTTTTT
CTAAAGGTGTACTTAATGAATACCCTGTTATAAAAAGACAATTCCTTAGCCCTATAACTATTAATAAATTAAGCTATGAT
TATTCATATTGA

Upstream 100 bases:

>100_bases
TGATAATAAATATTTTAGGCAAAAGACGAGTGCAAAAATTTTTGATAGGCTCAAGTGAGGCTTTATCTTGTGTAAGAAAA
ATAAAATGAGGAGGTTATAA

Downstream 100 bases:

>100_bases
ACCTATGAATAAAGGAATAGAGCAATGAAATGGTTTTGTCCTTATTGCTGGGCTGAACTAAAAGGGGATGAAAGGATATG
TCCCAATTGCGGGAAAGATA

Product: Cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MLESLIQEVSKKLEEGLCVELPDGRVLGSGNCKVKVKDKNVILNILKDPEMGFGEAYMKGAIEIDGDIERFLVACLNYLE
ENKQEKNFRNSLFRNILKYTGLLKFTEEKEVRSHYDLGNDFYKLWLDDSMTYSCAFFTDAHQSLEMAQKEKRKIIYGKLQ
LTDGDKLLDIGCGWGAIILEVSKLYNIEAVGITVSKNQYDYVKSKIENNGLSSRTRVYLMHYEDLPSLGEKFNKIVSVGM
FEHVGKGRHKDFFKIVHNTIEEKGLFLLHTIGKVLPESQSKWIRKYIFPGGYLPALTEIIEATKGSEFNLIDIDDWRLHY
YKTLQEWRKRFYKHAEEVVKKNGEEFFRMWDLYLIGSAVSFLTGSNHLFQILFSKGVLNEYPVIKRQFLSPITINKLSYD
YSY

Sequences:

>Translated_403_residues
MLESLIQEVSKKLEEGLCVELPDGRVLGSGNCKVKVKDKNVILNILKDPEMGFGEAYMKGAIEIDGDIERFLVACLNYLE
ENKQEKNFRNSLFRNILKYTGLLKFTEEKEVRSHYDLGNDFYKLWLDDSMTYSCAFFTDAHQSLEMAQKEKRKIIYGKLQ
LTDGDKLLDIGCGWGAIILEVSKLYNIEAVGITVSKNQYDYVKSKIENNGLSSRTRVYLMHYEDLPSLGEKFNKIVSVGM
FEHVGKGRHKDFFKIVHNTIEEKGLFLLHTIGKVLPESQSKWIRKYIFPGGYLPALTEIIEATKGSEFNLIDIDDWRLHY
YKTLQEWRKRFYKHAEEVVKKNGEEFFRMWDLYLIGSAVSFLTGSNHLFQILFSKGVLNEYPVIKRQFLSPITINKLSYD
YSY
>Mature_403_residues
MLESLIQEVSKKLEEGLCVELPDGRVLGSGNCKVKVKDKNVILNILKDPEMGFGEAYMKGAIEIDGDIERFLVACLNYLE
ENKQEKNFRNSLFRNILKYTGLLKFTEEKEVRSHYDLGNDFYKLWLDDSMTYSCAFFTDAHQSLEMAQKEKRKIIYGKLQ
LTDGDKLLDIGCGWGAIILEVSKLYNIEAVGITVSKNQYDYVKSKIENNGLSSRTRVYLMHYEDLPSLGEKFNKIVSVGM
FEHVGKGRHKDFFKIVHNTIEEKGLFLLHTIGKVLPESQSKWIRKYIFPGGYLPALTEIIEATKGSEFNLIDIDDWRLHY
YKTLQEWRKRFYKHAEEVVKKNGEEFFRMWDLYLIGSAVSFLTGSNHLFQILFSKGVLNEYPVIKRQFLSPITINKLSYD
YSY

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=365, Percent_Identity=35.6164383561644, Blast_Score=212, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI133904226, Length=374, Percent_Identity=30.2139037433155, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 46812; Mature: 46812

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESLIQEVSKKLEEGLCVELPDGRVLGSGNCKVKVKDKNVILNILKDPEMGFGEAYMKG
CHHHHHHHHHHHHHCCCEEECCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCHHHHCC
AIEIDGDIERFLVACLNYLEENKQEKNFRNSLFRNILKYTGLLKFTEEKEVRSHYDLGND
CEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHEECHHHHHHHHCCCCCC
FYKLWLDDSMTYSCAFFTDAHQSLEMAQKEKRKIIYGKLQLTDGDKLLDIGCGWGAIILE
EEEEEECCCCEEEEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VSKLYNIEAVGITVSKNQYDYVKSKIENNGLSSRTRVYLMHYEDLPSLGEKFNKIVSVGM
HHHHCCEEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHH
FEHVGKGRHKDFFKIVHNTIEEKGLFLLHTIGKVLPESQSKWIRKYIFPGGYLPALTEII
HHHHCCCCCHHHHHHHHHHHHHCCEEHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
EATKGSEFNLIDIDDWRLHYYKTLQEWRKRFYKHAEEVVKKNGEEFFRMWDLYLIGSAVS
HHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLTGSNHLFQILFSKGVLNEYPVIKRQFLSPITINKLSYDYSY
HHCCCHHHHHHHHHCCCCCCCCHHHHHHCCCEEEEEECCCCCC
>Mature Secondary Structure
MLESLIQEVSKKLEEGLCVELPDGRVLGSGNCKVKVKDKNVILNILKDPEMGFGEAYMKG
CHHHHHHHHHHHHHCCCEEECCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCHHHHCC
AIEIDGDIERFLVACLNYLEENKQEKNFRNSLFRNILKYTGLLKFTEEKEVRSHYDLGND
CEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHEECHHHHHHHHCCCCCC
FYKLWLDDSMTYSCAFFTDAHQSLEMAQKEKRKIIYGKLQLTDGDKLLDIGCGWGAIILE
EEEEEECCCCEEEEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VSKLYNIEAVGITVSKNQYDYVKSKIENNGLSSRTRVYLMHYEDLPSLGEKFNKIVSVGM
HHHHCCEEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHH
FEHVGKGRHKDFFKIVHNTIEEKGLFLLHTIGKVLPESQSKWIRKYIFPGGYLPALTEII
HHHHCCCCCHHHHHHHHHHHHHCCEEHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
EATKGSEFNLIDIDDWRLHYYKTLQEWRKRFYKHAEEVVKKNGEEFFRMWDLYLIGSAVS
HHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLTGSNHLFQILFSKGVLNEYPVIKRQFLSPITINKLSYDYSY
HHCCCHHHHHHHHHCCCCCCCCHHHHHHCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]