| Definition | Hydrogenobaculum sp. Y04AAS1 chromosome, complete genome. |
|---|---|
| Accession | NC_011126 |
| Length | 1,559,514 |
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The map label for this gene is ftsH
Identifier: 195952893
GI number: 195952893
Start: 455434
End: 457344
Strand: Direct
Name: ftsH
Synonym: HY04AAS1_0518
Alternate gene names: 195952893
Gene position: 455434-457344 (Clockwise)
Preceding gene: 195952892
Following gene: 195952894
Centisome position: 29.2
GC content: 37.94
Gene sequence:
>1911_bases TTGCAGACAGCTAAGAATATACTTATTTGGTTTTTAATTATAGGTTTTATGATAGTAGCTTTTAACTTGTTTGAGGAAAA AGGTTCATCCTCACCAAGTGCAACCCCTATGTCTTTAACAACATTGGTTGACATGGTAAAACAAAACAAAATAGGTGAGG CTGATATCAAAGGCGACAAGATAATAGCTTATACCAAAGACGGCCAGAAAGTAGAAACCTATATTCCAAAAGGTTATACA TCTATTATAGATGAAATGATAAAAGATGGAGTAAAGGTAAAAGCTTCACCATCTAGCGGAGGAGATATATCCTCCAGTGG AAACTGGCTTGTATCAATGCTAATATCTTGGTTTCCGGTACTTTTGTTTGCTGGTATTTGGATTTTAATGATGAGACAAA TGGGAAACGGTGGACCCACAAGAGCGTTCTCTTTTGGAAAATCTAAAGCGAAAGTGTATATAGAAGAAAAACCAAACGTA AAGCTAGACAATGTAGCTGGTATGGATGAAGTTAAAGAAGAAGTGGCTGAAGTTATAGAATATTTAAAAGACCCGGCAAG ATTTAGAAAATTAGGTGGTAGACCTCCAAAGGGAATACTGTTTTATGGAGAACCAGGCGTTGGAAAGACACTTTTAGCTA AGGCTCTTGCAGGAGAAGCACACGTACCTTTCATATCGGTATCTGGATCAGATTTTGTTGAGATGTTTGTAGGTGTAGGT GCCGCTAGAATGAGAGATACGTTTGAAACAGCTCGTAAAAATGCCCCTTGTATAGTATTTATAGATGAGATTGATGCGGT AGGAAGAAGCAGAGGGGCTATCAACCTAGGTGGTAACGACGAAAGAGAACAAACATTAAACCAGCTTCTGGTAGAAATGG ATGGTTTTGACACTTCTGAAGGTATACTCATAATAGCAGCTACAAATAGACCAGATATTTTAGATCCAGCTCTTCTAAGA CCAGGAAGGTTTGATAGACAAATATTTATTCCAAAGCCAGATGTAAAAGGAAGATACGAGATATTAAAAGTACACGCTAA AAATAAACCGCTTGCAAAGGATGTAGATTTAGAGCTTATAGCAAGAGCAACGCCCGGATTTACAGGAGCTGACCTTGAGA ACATATTAAACGAAGCAGCGCTTTTGGCAGCTAGAAAAAGAAAAGATCTTATACATATGGAGGATTTGGAAGAAGCTATA GATAGAGTTATGATGGGGTTGGAAAGAAGAGGTATGGCCATATCGCCAAAAGAAAAAGAAAAAATAGCTGTTCATGAAGC AGGACACGCTTTAATGGGGCTTATGATGCCAGACGCAGATCCTCTTCACAAAGTTTCAATTATACCAAGAGGTATGGCTT TGGGAGTGACTACTCAGCTTCCAATAGACGATAAGCATATTTACGATAAAGCAGATCTTCTTTCAAGAATACATATACTT ATGGGTGGAAGATGTGCGGAGGAAGTGTTTTACGGTAAGGATGGTATAACTACAGGAGCAGAAAATGACCTACAAAGGGC TACCGATTTAGCTTACCGTATAGTGGCTACTTGGGGAATGAGCGAGAATGTAGGACCAATATCTGTAAGAAGAAATATCA ATCCTTTCCTTGGGGGTTCTACAGTCACGGAAGGAAGCCCAGATCTTCTAAAAGAGATAGACAAAGAAGTGCAAAAACTC CTAGCATCTGCTTACGAAGAAACAAAAAGAGTTATAGCCGAGAACAAAGAAGCTTTAAGCAGTGTGGTAAAAAGGCTAAT AGAAAAAGAAACCATAGATTGTAAAGAATTTGTGGAGATACTTAGTTTACATGGCGTTGAGGTAAAAAATGCTTGTAAAC AAGAGGAATCTTTGGAGAAAAAAGAAAATAATGTAGAGCCTAAAATTGATAAAAATGTTGTTAACGTATGA
Upstream 100 bases:
>100_bases ATCAGAGAATTAACCTTGCAGAAAATATCTGGAAAAGTATTGCTAATTTTTAATTTTATTTTAAATTTATATTTATCACT TCATTTTGGAGGTAAGTGTT
Downstream 100 bases:
>100_bases GAAAGCCACTGTTGACAATAAATTTCTCATATTGTAAAATAGTTAGCTAGATTTTAAGAGGTGATTATATGGGACATACT ATTACTGAAAAAATAATTGC
Product: ATP-dependent metalloprotease FtsH
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 636; Mature: 636
Protein sequence:
>636_residues MQTAKNILIWFLIIGFMIVAFNLFEEKGSSSPSATPMSLTTLVDMVKQNKIGEADIKGDKIIAYTKDGQKVETYIPKGYT SIIDEMIKDGVKVKASPSSGGDISSSGNWLVSMLISWFPVLLFAGIWILMMRQMGNGGPTRAFSFGKSKAKVYIEEKPNV KLDNVAGMDEVKEEVAEVIEYLKDPARFRKLGGRPPKGILFYGEPGVGKTLLAKALAGEAHVPFISVSGSDFVEMFVGVG AARMRDTFETARKNAPCIVFIDEIDAVGRSRGAINLGGNDEREQTLNQLLVEMDGFDTSEGILIIAATNRPDILDPALLR PGRFDRQIFIPKPDVKGRYEILKVHAKNKPLAKDVDLELIARATPGFTGADLENILNEAALLAARKRKDLIHMEDLEEAI DRVMMGLERRGMAISPKEKEKIAVHEAGHALMGLMMPDADPLHKVSIIPRGMALGVTTQLPIDDKHIYDKADLLSRIHIL MGGRCAEEVFYGKDGITTGAENDLQRATDLAYRIVATWGMSENVGPISVRRNINPFLGGSTVTEGSPDLLKEIDKEVQKL LASAYEETKRVIAENKEALSSVVKRLIEKETIDCKEFVEILSLHGVEVKNACKQEESLEKKENNVEPKIDKNVVNV
Sequences:
>Translated_636_residues MQTAKNILIWFLIIGFMIVAFNLFEEKGSSSPSATPMSLTTLVDMVKQNKIGEADIKGDKIIAYTKDGQKVETYIPKGYT SIIDEMIKDGVKVKASPSSGGDISSSGNWLVSMLISWFPVLLFAGIWILMMRQMGNGGPTRAFSFGKSKAKVYIEEKPNV KLDNVAGMDEVKEEVAEVIEYLKDPARFRKLGGRPPKGILFYGEPGVGKTLLAKALAGEAHVPFISVSGSDFVEMFVGVG AARMRDTFETARKNAPCIVFIDEIDAVGRSRGAINLGGNDEREQTLNQLLVEMDGFDTSEGILIIAATNRPDILDPALLR PGRFDRQIFIPKPDVKGRYEILKVHAKNKPLAKDVDLELIARATPGFTGADLENILNEAALLAARKRKDLIHMEDLEEAI DRVMMGLERRGMAISPKEKEKIAVHEAGHALMGLMMPDADPLHKVSIIPRGMALGVTTQLPIDDKHIYDKADLLSRIHIL MGGRCAEEVFYGKDGITTGAENDLQRATDLAYRIVATWGMSENVGPISVRRNINPFLGGSTVTEGSPDLLKEIDKEVQKL LASAYEETKRVIAENKEALSSVVKRLIEKETIDCKEFVEILSLHGVEVKNACKQEESLEKKENNVEPKIDKNVVNV >Mature_636_residues MQTAKNILIWFLIIGFMIVAFNLFEEKGSSSPSATPMSLTTLVDMVKQNKIGEADIKGDKIIAYTKDGQKVETYIPKGYT SIIDEMIKDGVKVKASPSSGGDISSSGNWLVSMLISWFPVLLFAGIWILMMRQMGNGGPTRAFSFGKSKAKVYIEEKPNV KLDNVAGMDEVKEEVAEVIEYLKDPARFRKLGGRPPKGILFYGEPGVGKTLLAKALAGEAHVPFISVSGSDFVEMFVGVG AARMRDTFETARKNAPCIVFIDEIDAVGRSRGAINLGGNDEREQTLNQLLVEMDGFDTSEGILIIAATNRPDILDPALLR PGRFDRQIFIPKPDVKGRYEILKVHAKNKPLAKDVDLELIARATPGFTGADLENILNEAALLAARKRKDLIHMEDLEEAI DRVMMGLERRGMAISPKEKEKIAVHEAGHALMGLMMPDADPLHKVSIIPRGMALGVTTQLPIDDKHIYDKADLLSRIHIL MGGRCAEEVFYGKDGITTGAENDLQRATDLAYRIVATWGMSENVGPISVRRNINPFLGGSTVTEGSPDLLKEIDKEVQKL LASAYEETKRVIAENKEALSSVVKRLIEKETIDCKEFVEILSLHGVEVKNACKQEESLEKKENNVEPKIDKNVVNV
Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COG id: COG0465
COG function: function code O; ATP-dependent Zn proteases
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the peptidase M41 family
Homologues:
Organism=Homo sapiens, GI300192933, Length=512, Percent_Identity=49.609375, Blast_Score=457, Evalue=1e-128, Organism=Homo sapiens, GI21327685, Length=451, Percent_Identity=46.119733924612, Blast_Score=404, Evalue=1e-112, Organism=Homo sapiens, GI7657689, Length=451, Percent_Identity=46.119733924612, Blast_Score=403, Evalue=1e-112, Organism=Homo sapiens, GI4507173, Length=512, Percent_Identity=41.6015625, Blast_Score=372, Evalue=1e-103, Organism=Homo sapiens, GI6005942, Length=229, Percent_Identity=47.5982532751092, Blast_Score=228, Evalue=1e-59, Organism=Homo sapiens, GI4506209, Length=252, Percent_Identity=44.047619047619, Blast_Score=226, Evalue=7e-59, Organism=Homo sapiens, GI24497435, Length=264, Percent_Identity=42.8030303030303, Blast_Score=221, Evalue=2e-57, Organism=Homo sapiens, GI195539395, Length=252, Percent_Identity=44.4444444444444, Blast_Score=212, Evalue=8e-55, Organism=Homo sapiens, GI21361144, Length=248, Percent_Identity=39.9193548387097, Blast_Score=202, Evalue=8e-52, Organism=Homo sapiens, GI24430151, Length=252, Percent_Identity=40.4761904761905, Blast_Score=202, Evalue=1e-51, Organism=Homo sapiens, GI89064750, Length=251, Percent_Identity=41.4342629482072, Blast_Score=199, Evalue=8e-51, Organism=Homo sapiens, GI5729991, Length=251, Percent_Identity=41.4342629482072, Blast_Score=198, Evalue=1e-50, Organism=Homo sapiens, GI24430155, Length=251, Percent_Identity=41.4342629482072, Blast_Score=198, Evalue=1e-50, Organism=Homo sapiens, GI157671927, Length=249, Percent_Identity=39.7590361445783, Blast_Score=196, Evalue=8e-50, Organism=Homo sapiens, GI229577436, Length=244, Percent_Identity=43.8524590163934, Blast_Score=188, Evalue=1e-47, Organism=Homo sapiens, GI4505725, Length=222, Percent_Identity=43.2432432432432, Blast_Score=188, Evalue=2e-47, Organism=Homo sapiens, GI45643125, Length=235, Percent_Identity=41.2765957446808, Blast_Score=185, Evalue=1e-46, Organism=Homo sapiens, GI45643123, Length=235, Percent_Identity=41.2765957446808, Blast_Score=185, Evalue=1e-46, Organism=Homo sapiens, GI40806173, Length=208, Percent_Identity=47.5961538461538, Blast_Score=165, Evalue=1e-40, Organism=Homo sapiens, GI24497618, Length=291, Percent_Identity=35.3951890034364, Blast_Score=162, Evalue=6e-40, Organism=Homo sapiens, GI5901990, Length=277, Percent_Identity=37.1841155234657, Blast_Score=159, Evalue=7e-39, Organism=Homo sapiens, GI194018488, Length=248, Percent_Identity=39.9193548387097, Blast_Score=159, Evalue=1e-38, Organism=Homo sapiens, GI153792536, Length=291, Percent_Identity=34.7079037800687, Blast_Score=157, Evalue=4e-38, Organism=Homo sapiens, GI14149767, Length=244, Percent_Identity=37.2950819672131, Blast_Score=150, Evalue=3e-36, Organism=Homo sapiens, GI62177112, Length=244, Percent_Identity=37.2950819672131, Blast_Score=150, Evalue=3e-36, Organism=Homo sapiens, GI7019569, Length=246, Percent_Identity=36.1788617886179, Blast_Score=149, Evalue=1e-35, Organism=Homo sapiens, GI17865802, Length=244, Percent_Identity=37.2950819672131, Blast_Score=144, Evalue=2e-34, Organism=Homo sapiens, GI226371754, Length=245, Percent_Identity=35.1020408163265, Blast_Score=139, Evalue=9e-33, Organism=Homo sapiens, GI31742536, Length=232, Percent_Identity=33.6206896551724, Blast_Score=135, Evalue=1e-31, Organism=Homo sapiens, GI112789543, Length=232, Percent_Identity=33.6206896551724, Blast_Score=135, Evalue=1e-31, Organism=Homo sapiens, GI31377644, Length=238, Percent_Identity=35.7142857142857, Blast_Score=133, Evalue=6e-31, Organism=Homo sapiens, GI156564401, Length=217, Percent_Identity=36.405529953917, Blast_Score=128, Evalue=1e-29, Organism=Homo sapiens, GI310125280, Length=216, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=1e-28, Organism=Homo sapiens, GI11875211, Length=228, Percent_Identity=35.0877192982456, Blast_Score=124, Evalue=3e-28, Organism=Homo sapiens, GI310125282, Length=217, Percent_Identity=35.9447004608295, Blast_Score=124, Evalue=3e-28, Organism=Homo sapiens, GI40806170, Length=228, Percent_Identity=35.0877192982456, Blast_Score=124, Evalue=4e-28, Organism=Homo sapiens, GI64084766, Length=277, Percent_Identity=26.7148014440433, Blast_Score=99, Evalue=1e-20, Organism=Homo sapiens, GI116292174, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=2e-15, Organism=Escherichia coli, GI1789568, Length=633, Percent_Identity=47.8672985781991, Blast_Score=597, Evalue=1e-172, Organism=Caenorhabditis elegans, GI71994521, Length=465, Percent_Identity=49.0322580645161, Blast_Score=421, Evalue=1e-118, Organism=Caenorhabditis elegans, GI17554264, Length=462, Percent_Identity=44.8051948051948, Blast_Score=388, Evalue=1e-108, Organism=Caenorhabditis elegans, GI115534323, Length=474, Percent_Identity=43.0379746835443, Blast_Score=363, Evalue=1e-100, Organism=Caenorhabditis elegans, GI17554786, Length=264, Percent_Identity=43.5606060606061, Blast_Score=228, Evalue=7e-60, Organism=Caenorhabditis elegans, GI25144281, Length=264, Percent_Identity=43.5606060606061, Blast_Score=226, Evalue=4e-59, Organism=Caenorhabditis elegans, GI17563248, Length=254, Percent_Identity=44.4881889763779, Blast_Score=226, Evalue=4e-59, Organism=Caenorhabditis elegans, GI25144278, Length=264, Percent_Identity=43.5606060606061, Blast_Score=225, Evalue=4e-59, Organism=Caenorhabditis elegans, GI17532375, Length=250, Percent_Identity=44, Blast_Score=224, Evalue=1e-58, Organism=Caenorhabditis elegans, GI17531535, Length=249, Percent_Identity=44.1767068273092, Blast_Score=217, Evalue=2e-56, Organism=Caenorhabditis elegans, GI17563250, Length=252, Percent_Identity=41.6666666666667, Blast_Score=209, Evalue=5e-54, Organism=Caenorhabditis elegans, GI71987372, Length=254, Percent_Identity=41.3385826771654, Blast_Score=205, Evalue=7e-53, Organism=Caenorhabditis elegans, GI71987364, Length=254, Percent_Identity=41.3385826771654, Blast_Score=205, Evalue=7e-53, Organism=Caenorhabditis elegans, GI17508701, Length=248, Percent_Identity=40.3225806451613, Blast_Score=202, Evalue=3e-52, Organism=Caenorhabditis elegans, GI17505546, Length=253, Percent_Identity=41.1067193675889, Blast_Score=202, Evalue=6e-52, Organism=Caenorhabditis elegans, GI17554784, Length=251, Percent_Identity=41.4342629482072, Blast_Score=191, Evalue=1e-48, Organism=Caenorhabditis elegans, GI17508053, Length=256, Percent_Identity=41.40625, Blast_Score=186, Evalue=3e-47, Organism=Caenorhabditis elegans, GI17537217, Length=239, Percent_Identity=42.6778242677824, Blast_Score=172, Evalue=4e-43, Organism=Caenorhabditis elegans, GI25153574, Length=227, Percent_Identity=38.3259911894273, Blast_Score=157, Evalue=1e-38, Organism=Caenorhabditis elegans, GI133931034, Length=245, Percent_Identity=37.9591836734694, Blast_Score=155, Evalue=7e-38, Organism=Caenorhabditis elegans, GI193206116, Length=245, Percent_Identity=37.9591836734694, Blast_Score=155, Evalue=8e-38, Organism=Caenorhabditis elegans, GI193209502, Length=227, Percent_Identity=38.3259911894273, Blast_Score=155, Evalue=8e-38, Organism=Caenorhabditis elegans, GI193206114, Length=245, Percent_Identity=37.9591836734694, Blast_Score=155, Evalue=8e-38, Organism=Caenorhabditis elegans, GI17562804, Length=233, Percent_Identity=37.3390557939914, Blast_Score=151, Evalue=9e-37, Organism=Caenorhabditis elegans, GI86561515, Length=246, Percent_Identity=36.1788617886179, Blast_Score=141, Evalue=1e-33, Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=45.4545454545455, Blast_Score=141, Evalue=1e-33, Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=45.4545454545455, Blast_Score=141, Evalue=1e-33, Organism=Caenorhabditis elegans, GI17541224, Length=256, Percent_Identity=34.375, Blast_Score=127, Evalue=1e-29, Organism=Caenorhabditis elegans, GI25146157, Length=233, Percent_Identity=37.3390557939914, Blast_Score=127, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17541226, Length=256, Percent_Identity=34.375, Blast_Score=127, Evalue=2e-29, Organism=Caenorhabditis elegans, GI32563584, Length=233, Percent_Identity=36.9098712446352, Blast_Score=126, Evalue=4e-29, Organism=Caenorhabditis elegans, GI17508421, Length=233, Percent_Identity=36.9098712446352, Blast_Score=126, Evalue=4e-29, Organism=Caenorhabditis elegans, GI133901662, Length=209, Percent_Identity=37.799043062201, Blast_Score=124, Evalue=2e-28, Organism=Caenorhabditis elegans, GI133901658, Length=209, Percent_Identity=37.799043062201, Blast_Score=123, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17560432, Length=279, Percent_Identity=29.0322580645161, Blast_Score=112, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17570511, Length=147, Percent_Identity=34.0136054421769, Blast_Score=72, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6323736, Length=502, Percent_Identity=45.2191235059761, Blast_Score=417, Evalue=1e-117, Organism=Saccharomyces cerevisiae, GI6320854, Length=537, Percent_Identity=42.8305400372439, Blast_Score=406, Evalue=1e-114, Organism=Saccharomyces cerevisiae, GI6325281, Length=446, Percent_Identity=45.7399103139013, Blast_Score=393, Evalue=1e-110, Organism=Saccharomyces cerevisiae, GI6322704, Length=257, Percent_Identity=43.9688715953307, Blast_Score=225, Evalue=1e-59, Organism=Saccharomyces cerevisiae, GI6321390, Length=252, Percent_Identity=44.047619047619, Blast_Score=221, Evalue=3e-58, Organism=Saccharomyces cerevisiae, GI6320077, Length=263, Percent_Identity=44.4866920152091, Blast_Score=215, Evalue=2e-56, Organism=Saccharomyces cerevisiae, GI6324833, Length=249, Percent_Identity=43.3734939759036, Blast_Score=207, Evalue=3e-54, Organism=Saccharomyces cerevisiae, GI6320197, Length=252, Percent_Identity=39.6825396825397, Blast_Score=204, Evalue=5e-53, Organism=Saccharomyces cerevisiae, GI6324691, Length=251, Percent_Identity=39.8406374501992, Blast_Score=199, Evalue=9e-52, Organism=Saccharomyces cerevisiae, GI6320602, Length=246, Percent_Identity=43.0894308943089, Blast_Score=195, Evalue=2e-50, Organism=Saccharomyces cerevisiae, GI6322994, Length=249, Percent_Identity=36.9477911646586, Blast_Score=179, Evalue=2e-45, Organism=Saccharomyces cerevisiae, GI6324000, Length=233, Percent_Identity=41.2017167381974, Blast_Score=169, Evalue=9e-43, Organism=Saccharomyces cerevisiae, GI6323429, Length=257, Percent_Identity=39.2996108949416, Blast_Score=168, Evalue=2e-42, Organism=Saccharomyces cerevisiae, GI6321709, Length=240, Percent_Identity=37.5, Blast_Score=168, Evalue=3e-42, Organism=Saccharomyces cerevisiae, GI6322651, Length=248, Percent_Identity=37.0967741935484, Blast_Score=166, Evalue=1e-41, Organism=Saccharomyces cerevisiae, GI6325431, Length=255, Percent_Identity=38.4313725490196, Blast_Score=160, Evalue=7e-40, Organism=Saccharomyces cerevisiae, GI6325183, Length=253, Percent_Identity=32.4110671936759, Blast_Score=132, Evalue=2e-31, Organism=Saccharomyces cerevisiae, GI6321465, Length=232, Percent_Identity=36.6379310344828, Blast_Score=129, Evalue=1e-30, Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=37.037037037037, Blast_Score=127, Evalue=4e-30, Organism=Saccharomyces cerevisiae, GI6320887, Length=244, Percent_Identity=30.7377049180328, Blast_Score=119, Evalue=1e-27, Organism=Saccharomyces cerevisiae, GI6320583, Length=216, Percent_Identity=28.7037037037037, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24665814, Length=500, Percent_Identity=47, Blast_Score=442, Evalue=1e-124, Organism=Drosophila melanogaster, GI28574878, Length=500, Percent_Identity=47, Blast_Score=442, Evalue=1e-124, Organism=Drosophila melanogaster, GI24639391, Length=461, Percent_Identity=44.2516268980477, Blast_Score=390, Evalue=1e-108, Organism=Drosophila melanogaster, GI24658770, Length=508, Percent_Identity=41.3385826771654, Blast_Score=385, Evalue=1e-107, Organism=Drosophila melanogaster, GI17137560, Length=233, Percent_Identity=47.6394849785408, Blast_Score=228, Evalue=1e-59, Organism=Drosophila melanogaster, GI161076488, Length=233, Percent_Identity=47.6394849785408, Blast_Score=228, Evalue=1e-59, Organism=Drosophila melanogaster, GI161076486, Length=234, Percent_Identity=47.8632478632479, Blast_Score=228, Evalue=1e-59, Organism=Drosophila melanogaster, GI19920408, Length=262, Percent_Identity=43.5114503816794, Blast_Score=224, Evalue=1e-58, Organism=Drosophila melanogaster, GI24651451, Length=263, Percent_Identity=42.5855513307985, Blast_Score=218, Evalue=9e-57, Organism=Drosophila melanogaster, GI17137738, Length=252, Percent_Identity=42.4603174603175, Blast_Score=217, Evalue=2e-56, Organism=Drosophila melanogaster, GI17738151, Length=248, Percent_Identity=39.9193548387097, Blast_Score=208, Evalue=7e-54, Organism=Drosophila melanogaster, GI24640100, Length=250, Percent_Identity=43.2, Blast_Score=206, Evalue=5e-53, Organism=Drosophila melanogaster, GI24652279, Length=216, Percent_Identity=47.6851851851852, Blast_Score=202, Evalue=7e-52, Organism=Drosophila melanogaster, GI24649446, Length=252, Percent_Identity=40.8730158730159, Blast_Score=202, Evalue=7e-52, Organism=Drosophila melanogaster, GI24663015, Length=252, Percent_Identity=43.2539682539683, Blast_Score=200, Evalue=2e-51, Organism=Drosophila melanogaster, GI18860063, Length=245, Percent_Identity=41.6326530612245, Blast_Score=198, Evalue=8e-51, Organism=Drosophila melanogaster, GI19921202, Length=253, Percent_Identity=40.7114624505929, Blast_Score=198, Evalue=1e-50, Organism=Drosophila melanogaster, GI45554047, Length=165, Percent_Identity=55.1515151515151, Blast_Score=194, Evalue=1e-49, Organism=Drosophila melanogaster, GI24660075, Length=235, Percent_Identity=43.8297872340426, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI281365776, Length=235, Percent_Identity=43.8297872340426, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI281361487, Length=245, Percent_Identity=40, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI45552965, Length=235, Percent_Identity=43.8297872340426, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI24656820, Length=245, Percent_Identity=40.8163265306122, Blast_Score=183, Evalue=4e-46, Organism=Drosophila melanogaster, GI24656825, Length=245, Percent_Identity=40.8163265306122, Blast_Score=183, Evalue=4e-46, Organism=Drosophila melanogaster, GI281363136, Length=240, Percent_Identity=40.8333333333333, Blast_Score=167, Evalue=2e-41, Organism=Drosophila melanogaster, GI78707192, Length=240, Percent_Identity=40.8333333333333, Blast_Score=167, Evalue=2e-41, Organism=Drosophila melanogaster, GI21355121, Length=231, Percent_Identity=35.0649350649351, Blast_Score=153, Evalue=4e-37, Organism=Drosophila melanogaster, GI18859657, Length=244, Percent_Identity=38.5245901639344, Blast_Score=149, Evalue=6e-36, Organism=Drosophila melanogaster, GI281360144, Length=240, Percent_Identity=35, Blast_Score=138, Evalue=1e-32, Organism=Drosophila melanogaster, GI281360140, Length=240, Percent_Identity=35, Blast_Score=138, Evalue=1e-32, Organism=Drosophila melanogaster, GI281360136, Length=240, Percent_Identity=35, Blast_Score=138, Evalue=1e-32, Organism=Drosophila melanogaster, GI24644411, Length=240, Percent_Identity=35, Blast_Score=138, Evalue=1e-32, Organism=Drosophila melanogaster, GI281360142, Length=243, Percent_Identity=34.9794238683128, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI21357333, Length=243, Percent_Identity=34.9794238683128, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI281360146, Length=243, Percent_Identity=34.9794238683128, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI281360138, Length=243, Percent_Identity=34.9794238683128, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI24644145, Length=239, Percent_Identity=33.4728033472803, Blast_Score=134, Evalue=2e-31, Organism=Drosophila melanogaster, GI20129529, Length=240, Percent_Identity=34.5833333333333, Blast_Score=132, Evalue=8e-31, Organism=Drosophila melanogaster, GI20129423, Length=233, Percent_Identity=33.9055793991416, Blast_Score=128, Evalue=1e-29, Organism=Drosophila melanogaster, GI17864540, Length=209, Percent_Identity=38.2775119617225, Blast_Score=127, Evalue=3e-29, Organism=Drosophila melanogaster, GI28573010, Length=216, Percent_Identity=37.5, Blast_Score=125, Evalue=6e-29, Organism=Drosophila melanogaster, GI24581396, Length=238, Percent_Identity=35.2941176470588, Blast_Score=123, Evalue=3e-28, Organism=Drosophila melanogaster, GI28571849, Length=234, Percent_Identity=33.7606837606838, Blast_Score=115, Evalue=9e-26, Organism=Drosophila melanogaster, GI28571847, Length=234, Percent_Identity=33.7606837606838, Blast_Score=115, Evalue=9e-26, Organism=Drosophila melanogaster, GI24639486, Length=244, Percent_Identity=29.5081967213115, Blast_Score=94, Evalue=4e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): FTSH_HYDS0 (B4U7U4)
Other databases:
- EMBL: CP001130 - RefSeq: YP_002121183.1 - MEROPS: M41.001 - GeneID: 6743314 - GenomeReviews: CP001130_GR - KEGG: hya:HY04AAS1_0518 - HOGENOM: HBG724153 - OMA: ELDNRVQ - ProtClustDB: CLSK2299557 - GO: GO:0006508 - HAMAP: MF_01458 - InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR005936 - InterPro: IPR011546 - InterPro: IPR000642 - SMART: SM00382 - TIGRFAMs: TIGR01241
Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41
EC number: 3.4.24.-
Molecular weight: Translated: 70037; Mature: 70037
Theoretical pI: Translated: 5.80; Mature: 5.80
Prosite motif: PS00674 AAA
Important sites: ACT_SITE 426-426
Signals:
None
Transmembrane regions:
HASH(0x2140451c)-; HASH(0x2565b2ec)-;
Cys/Met content:
0.6 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQTAKNILIWFLIIGFMIVAFNLFEEKGSSSPSATPMSLTTLVDMVKQNKIGEADIKGDK CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCE IIAYTKDGQKVETYIPKGYTSIIDEMIKDGVKVKASPSSGGDISSSGNWLVSMLISWFPV EEEECCCCCEEEHHCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH LLFAGIWILMMRQMGNGGPTRAFSFGKSKAKVYIEEKPNVKLDNVAGMDEVKEEVAEVIE HHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHH YLKDPARFRKLGGRPPKGILFYGEPGVGKTLLAKALAGEAHVPFISVSGSDFVEMFVGVG HHHCHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCC AARMRDTFETARKNAPCIVFIDEIDAVGRSRGAINLGGNDEREQTLNQLLVEMDGFDTSE HHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCC GILIIAATNRPDILDPALLRPGRFDRQIFIPKPDVKGRYEILKVHAKNKPLAKDVDLELI CEEEEEECCCCCCCCHHHCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHE ARATPGFTGADLENILNEAALLAARKRKDLIHMEDLEEAIDRVMMGLERRGMAISPKEKE EECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHH KIAVHEAGHALMGLMMPDADPLHKVSIIPRGMALGVTTQLPIDDKHIYDKADLLSRIHIL HHHHHHHCHHHHHHCCCCCCCCCEEEECCCCEEECCEEECCCCCHHHHHHHHHHHHHHHH MGGRCAEEVFYGKDGITTGAENDLQRATDLAYRIVATWGMSENVGPISVRRNINPFLGGS HCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCC TVTEGSPDLLKEIDKEVQKLLASAYEETKRVIAENKEALSSVVKRLIEKETIDCKEFVEI CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHH LSLHGVEVKNACKQEESLEKKENNVEPKIDKNVVNV HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH >Mature Secondary Structure MQTAKNILIWFLIIGFMIVAFNLFEEKGSSSPSATPMSLTTLVDMVKQNKIGEADIKGDK CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCE IIAYTKDGQKVETYIPKGYTSIIDEMIKDGVKVKASPSSGGDISSSGNWLVSMLISWFPV EEEECCCCCEEEHHCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH LLFAGIWILMMRQMGNGGPTRAFSFGKSKAKVYIEEKPNVKLDNVAGMDEVKEEVAEVIE HHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHH YLKDPARFRKLGGRPPKGILFYGEPGVGKTLLAKALAGEAHVPFISVSGSDFVEMFVGVG HHHCHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCC AARMRDTFETARKNAPCIVFIDEIDAVGRSRGAINLGGNDEREQTLNQLLVEMDGFDTSE HHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCC GILIIAATNRPDILDPALLRPGRFDRQIFIPKPDVKGRYEILKVHAKNKPLAKDVDLELI CEEEEEECCCCCCCCHHHCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHE ARATPGFTGADLENILNEAALLAARKRKDLIHMEDLEEAIDRVMMGLERRGMAISPKEKE EECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHH KIAVHEAGHALMGLMMPDADPLHKVSIIPRGMALGVTTQLPIDDKHIYDKADLLSRIHIL HHHHHHHCHHHHHHCCCCCCCCCEEEECCCCEEECCEEECCCCCHHHHHHHHHHHHHHHH MGGRCAEEVFYGKDGITTGAENDLQRATDLAYRIVATWGMSENVGPISVRRNINPFLGGS HCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCC TVTEGSPDLLKEIDKEVQKLLASAYEETKRVIAENKEALSSVVKRLIEKETIDCKEFVEI CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHH LSLHGVEVKNACKQEESLEKKENNVEPKIDKNVVNV HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA