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The map label for this gene is dprE1 [H]

Identifier: 195952864

GI number: 195952864

Start: 429845

End: 431122

Strand: Direct

Name: dprE1 [H]

Synonym: HY04AAS1_0489

Alternate gene names: 195952864

Gene position: 429845-431122 (Clockwise)

Preceding gene: 195952863

Following gene: 195952865

Centisome position: 27.56

GC content: 32.63

Gene sequence:

>1278_bases
ATGAATACATCAAAAAACCTTAGTTTTCTCTGTGGGTGGGGTAGATTTCCTTGCATAGAAGCAAATGTTTTAGATAAAGT
AGATTTTTCTAAAAGCTTTATACCAAGAGCTTACGGTAGAAGTTACGGCGATGAAGCTTTGTATAAAAATATATACGATA
CAACGGGTTTAAATCTATTTTTAAATGTAGATTTTGAAAAAGAATACATAGAAGTTCAATCTGGTATACAACTTCAAAAA
TTATTGGAGTTTTTATTACCAAGAGGATACGCTTTGCCGATAGTTCCTGGTACTTCTCTTATAAGTGTAGGTGGTGCTAT
AGCAAACGATATACACGGCAAAAGCTCAAAGGGGGTTTTTGGAGATTTTATAGAGGGTTTTGAAATAATAACACCAAGAG
GTGTTTATCAGTGCTCTAAAGAAAAAAACAGTGAGCTTTTTTGGGGTGCTATAGGGTCAATGGGCCTTCTTGGAATTATC
ACAAAAGCTAAACTAAAGATAGTAAAGGCAAGCCAGTATATAAGACAAAATATCATACCTACCAAAGGCATAGACAAGGC
TATAGAGTTATTGGAAACATTTGACAAAAATTACGAATTTTCAGTATGTTGGATAGACGCTTTTACCGAAAATGCTTTGG
TAATGTTTGGAGATTATGAGTATTATGAAAAGCTTCCTCTTGATTTAAAATTTAGTTTTAAGGCTTTTAAAAGCAAAAAA
ACAATAGATATACCTTTTGTGATGCCAAACTTTATCTTAAACGATATGGATATAAGAGCTTACAATGTTTATTATTTTAC
CAAGATGCCAAAAGGCGAATCTTTGGTACATTATTTTGATTTTTTCTTTCCTTTGGACAATATAAAAAATTGGAACAGAT
TTTACGGCAAAAGAGGGTTTTTGCAATATCAGTTTGTAGGACCAAAAGAGGCTTGTTTTGAAGTTTTTGATATTATAAAA
TCTCATAAGATATATCCATATCTAGTGGTGTTAAAAAGAATGAAAAACGCTTCAAATAGAGTGTTTTCTTTTGCGAAAGA
GGGCTTTACGCTGGCCTTAGATTTTCCAGTGAAAGACGATGTCCTTAAGATGCTTCATAAATTTGACGATGTCGTTGTGC
GTTATAACGGACTTATATACATGGCAAAGGATTCAAGGCTTCCTAAAGACGTGTTTCAGCATATATACAAAGACCAAATA
AAAGCTTTATTATCTTTAAAAGCCAAATACGATGAGAATTTTATACTAAAGTCTTTGATGTCAGAACGGCTTTTGTGA

Upstream 100 bases:

>100_bases
AACGAAAAGAAGGATATATTAATTTGTGGTAATTGTAAACTCGTTTACGAGATTGAAGAAGATATACCAATTCTTCTTGT
AGAACAAGCAAAACCTCTTG

Downstream 100 bases:

>100_bases
GATAATTAATAAATGGAGAAAATCGTTATAACCGGAAGAGCAAACGTTGGTAAATCTACACTATTTAACAAGATTTCCAA
AAGAAGGATATCGATAGTAG

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MNTSKNLSFLCGWGRFPCIEANVLDKVDFSKSFIPRAYGRSYGDEALYKNIYDTTGLNLFLNVDFEKEYIEVQSGIQLQK
LLEFLLPRGYALPIVPGTSLISVGGAIANDIHGKSSKGVFGDFIEGFEIITPRGVYQCSKEKNSELFWGAIGSMGLLGII
TKAKLKIVKASQYIRQNIIPTKGIDKAIELLETFDKNYEFSVCWIDAFTENALVMFGDYEYYEKLPLDLKFSFKAFKSKK
TIDIPFVMPNFILNDMDIRAYNVYYFTKMPKGESLVHYFDFFFPLDNIKNWNRFYGKRGFLQYQFVGPKEACFEVFDIIK
SHKIYPYLVVLKRMKNASNRVFSFAKEGFTLALDFPVKDDVLKMLHKFDDVVVRYNGLIYMAKDSRLPKDVFQHIYKDQI
KALLSLKAKYDENFILKSLMSERLL

Sequences:

>Translated_425_residues
MNTSKNLSFLCGWGRFPCIEANVLDKVDFSKSFIPRAYGRSYGDEALYKNIYDTTGLNLFLNVDFEKEYIEVQSGIQLQK
LLEFLLPRGYALPIVPGTSLISVGGAIANDIHGKSSKGVFGDFIEGFEIITPRGVYQCSKEKNSELFWGAIGSMGLLGII
TKAKLKIVKASQYIRQNIIPTKGIDKAIELLETFDKNYEFSVCWIDAFTENALVMFGDYEYYEKLPLDLKFSFKAFKSKK
TIDIPFVMPNFILNDMDIRAYNVYYFTKMPKGESLVHYFDFFFPLDNIKNWNRFYGKRGFLQYQFVGPKEACFEVFDIIK
SHKIYPYLVVLKRMKNASNRVFSFAKEGFTLALDFPVKDDVLKMLHKFDDVVVRYNGLIYMAKDSRLPKDVFQHIYKDQI
KALLSLKAKYDENFILKSLMSERLL
>Mature_425_residues
MNTSKNLSFLCGWGRFPCIEANVLDKVDFSKSFIPRAYGRSYGDEALYKNIYDTTGLNLFLNVDFEKEYIEVQSGIQLQK
LLEFLLPRGYALPIVPGTSLISVGGAIANDIHGKSSKGVFGDFIEGFEIITPRGVYQCSKEKNSELFWGAIGSMGLLGII
TKAKLKIVKASQYIRQNIIPTKGIDKAIELLETFDKNYEFSVCWIDAFTENALVMFGDYEYYEKLPLDLKFSFKAFKSKK
TIDIPFVMPNFILNDMDIRAYNVYYFTKMPKGESLVHYFDFFFPLDNIKNWNRFYGKRGFLQYQFVGPKEACFEVFDIIK
SHKIYPYLVVLKRMKNASNRVFSFAKEGFTLALDFPVKDDVLKMLHKFDDVVVRYNGLIYMAKDSRLPKDVFQHIYKDQI
KALLSLKAKYDENFILKSLMSERLL

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI13375618, Length=143, Percent_Identity=27.972027972028, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17568041, Length=175, Percent_Identity=27.4285714285714, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 49131; Mature: 49131

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSKNLSFLCGWGRFPCIEANVLDKVDFSKSFIPRAYGRSYGDEALYKNIYDTTGLNLF
CCCCCCCEEEECCCCCCEECCCHHCCCCCCHHHCCHHHCCCCCHHHHHHHHHCCCCCEEE
LNVDFEKEYIEVQSGIQLQKLLEFLLPRGYALPIVPGTSLISVGGAIANDIHGKSSKGVF
EEECCCHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCHHHHHCCHHHHCCCCCCCCCCH
GDFIEGFEIITPRGVYQCSKEKNSELFWGAIGSMGLLGIITKAKLKIVKASQYIRQNIIP
HHHHCCEEEECCCCHHECCCCCCCCEEEECHHHHHHHHHHHHHHHEEHHHHHHHHHCCCC
TKGIDKAIELLETFDKNYEFSVCWIDAFTENALVMFGDYEYYEKLPLDLKFSFKAFKSKK
CCCHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEECHHHHHHCCCCEEEEHHHHCCCC
TIDIPFVMPNFILNDMDIRAYNVYYFTKMPKGESLVHYFDFFFPLDNIKNWNRFYGKRGF
CEEECEECHHHHCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCHHHCCHHHHHHCCCCC
LQYQFVGPKEACFEVFDIIKSHKIYPYLVVLKRMKNASNRVFSFAKEGFTLALDFPVKDD
EEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHCCCEEEEEECCCCHH
VLKMLHKFDDVVVRYNGLIYMAKDSRLPKDVFQHIYKDQIKALLSLKAKYDENFILKSLM
HHHHHHHHHHEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SERLL
HHHCC
>Mature Secondary Structure
MNTSKNLSFLCGWGRFPCIEANVLDKVDFSKSFIPRAYGRSYGDEALYKNIYDTTGLNLF
CCCCCCCEEEECCCCCCEECCCHHCCCCCCHHHCCHHHCCCCCHHHHHHHHHCCCCCEEE
LNVDFEKEYIEVQSGIQLQKLLEFLLPRGYALPIVPGTSLISVGGAIANDIHGKSSKGVF
EEECCCHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCHHHHHCCHHHHCCCCCCCCCCH
GDFIEGFEIITPRGVYQCSKEKNSELFWGAIGSMGLLGIITKAKLKIVKASQYIRQNIIP
HHHHCCEEEECCCCHHECCCCCCCCEEEECHHHHHHHHHHHHHHHEEHHHHHHHHHCCCC
TKGIDKAIELLETFDKNYEFSVCWIDAFTENALVMFGDYEYYEKLPLDLKFSFKAFKSKK
CCCHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEECHHHHHHCCCCEEEEHHHHCCCC
TIDIPFVMPNFILNDMDIRAYNVYYFTKMPKGESLVHYFDFFFPLDNIKNWNRFYGKRGF
CEEECEECHHHHCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCHHHCCHHHHHHCCCCC
LQYQFVGPKEACFEVFDIIKSHKIYPYLVVLKRMKNASNRVFSFAKEGFTLALDFPVKDD
EEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHCCCEEEEEECCCCHH
VLKMLHKFDDVVVRYNGLIYMAKDSRLPKDVFQHIYKDQIKALLSLKAKYDENFILKSLM
HHHHHHHHHHEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SERLL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]