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The map label for this gene is der [H]

Identifier: 195952865

GI number: 195952865

Start: 431135

End: 432424

Strand: Direct

Name: der [H]

Synonym: HY04AAS1_0490

Alternate gene names: 195952865

Gene position: 431135-432424 (Clockwise)

Preceding gene: 195952864

Following gene: 195952866

Centisome position: 27.65

GC content: 33.1

Gene sequence:

>1290_bases
ATGGAGAAAATCGTTATAACCGGAAGAGCAAACGTTGGTAAATCTACACTATTTAACAAGATTTCCAAAAGAAGGATATC
GATAGTAGAAAATATACCAGGGATCACAAGAGATGTGATAGAGTCTAAAGCTGTTTTTCAAGATAAGGTTTTTAAGCTGG
TGGATACCGGTGGTTTGACAGATTCTAAAGAAGAGATATCTCAAGCTATAAGGGATAAAGTGCTTAAACTTTACAAAGAA
GCTTATAAGATAATATTTGTAGTGGATGGCAAGACCGGGCTTATGCCAGAAGATAAAGATATTGCTAAGCTTCTTTACCC
TTATAAAGAAAAAGTTTATGTGGCGGTAAACAAAACAGATAGTAAAAAAGCCAGTGCTTCAGAGTTTTATGAGCTTGGGT
TTGATAACGTATTTGAGATTTCAGCCACTCATGGTACCGGTGTTTTTGAGCTTTTAGAAGAGATAACAAAAGATTTAAAA
GCTATGGAAGAGCTAGAAGAAAAGGCTGATTTTATAAAACTAAGCTTTGTTGGAAAGCCAAATAGTGGTAAATCTTCTTT
GCTAAACTCTATTTTAAAGCAAGATAGAGTGATAGTTTCAAACATAGCTGGCACTACAAGAGACGCTGTTGATGTAGAGT
TTAGCTATGAAGGTAAAGATTTTATCTTGGTGGATACTGCTGGTATAAGAAGGCCTTCAAATATAGATTATGGTGTAGAG
TTTTTTGCGGTAAATAGAAGTTTAGAAGCTATAGAAAAATCAGATGTTTGTGCTCTTGTGATAGATGCTACAGAAGGAGT
TTCAAGGCAAGACATGAGGCTTGCTAGTCTTGTGAATAGGAAAGGTAAGGGGCTTATAGTGGTATTAAACAAAATAGATT
TGATAAAAGACATCGAGGCTCTTAAAAAACACGTAGATAAAAAGTTAGAGTTTGTTTATTTTGCTCCAAGAGTTTACGTA
TCCGCAAAAGAAGGTATAAATGTTTTTTCTATACTGCAAAAAGCTATAGATATTTACGAAGAATATTCAAAGCCTATTAA
GACTTCCTATGTAAATAGAGTTGTAGAAAAAATTTTAGAAGAGTATCCACAAAACTCAACAAAATCTATAAAAGTTTATT
ATACAGTATTTTCGCCAAAGCCTCCAACCATTGTGCTTCATACCAACAACAAAGATTTTTGGAGAGAGGATTATCTTAGA
TTTTTTGAGAAAAAGTTAAGAGAGAAACTAAATATAAACTATGCACCTTTAAATATAATATTAAAAGAGCATCAAAAGAA
AGAGGTATAG

Upstream 100 bases:

>100_bases
AGACCAAATAAAAGCTTTATTATCTTTAAAAGCCAAATACGATGAGAATTTTATACTAAAGTCTTTGATGTCAGAACGGC
TTTTGTGAGATAATTAATAA

Downstream 100 bases:

>100_bases
ATTATGAACAACGTTTTAATGGGGATTGCAAAAGCTGGTATAAAAGAATCTGGAAAAGAAGATTTGCTTGTGATAAAGCT
TCCCTTTGCCTGCGAATCTC

Product: small GTP-binding protein

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MEKIVITGRANVGKSTLFNKISKRRISIVENIPGITRDVIESKAVFQDKVFKLVDTGGLTDSKEEISQAIRDKVLKLYKE
AYKIIFVVDGKTGLMPEDKDIAKLLYPYKEKVYVAVNKTDSKKASASEFYELGFDNVFEISATHGTGVFELLEEITKDLK
AMEELEEKADFIKLSFVGKPNSGKSSLLNSILKQDRVIVSNIAGTTRDAVDVEFSYEGKDFILVDTAGIRRPSNIDYGVE
FFAVNRSLEAIEKSDVCALVIDATEGVSRQDMRLASLVNRKGKGLIVVLNKIDLIKDIEALKKHVDKKLEFVYFAPRVYV
SAKEGINVFSILQKAIDIYEEYSKPIKTSYVNRVVEKILEEYPQNSTKSIKVYYTVFSPKPPTIVLHTNNKDFWREDYLR
FFEKKLREKLNINYAPLNIILKEHQKKEV

Sequences:

>Translated_429_residues
MEKIVITGRANVGKSTLFNKISKRRISIVENIPGITRDVIESKAVFQDKVFKLVDTGGLTDSKEEISQAIRDKVLKLYKE
AYKIIFVVDGKTGLMPEDKDIAKLLYPYKEKVYVAVNKTDSKKASASEFYELGFDNVFEISATHGTGVFELLEEITKDLK
AMEELEEKADFIKLSFVGKPNSGKSSLLNSILKQDRVIVSNIAGTTRDAVDVEFSYEGKDFILVDTAGIRRPSNIDYGVE
FFAVNRSLEAIEKSDVCALVIDATEGVSRQDMRLASLVNRKGKGLIVVLNKIDLIKDIEALKKHVDKKLEFVYFAPRVYV
SAKEGINVFSILQKAIDIYEEYSKPIKTSYVNRVVEKILEEYPQNSTKSIKVYYTVFSPKPPTIVLHTNNKDFWREDYLR
FFEKKLREKLNINYAPLNIILKEHQKKEV
>Mature_429_residues
MEKIVITGRANVGKSTLFNKISKRRISIVENIPGITRDVIESKAVFQDKVFKLVDTGGLTDSKEEISQAIRDKVLKLYKE
AYKIIFVVDGKTGLMPEDKDIAKLLYPYKEKVYVAVNKTDSKKASASEFYELGFDNVFEISATHGTGVFELLEEITKDLK
AMEELEEKADFIKLSFVGKPNSGKSSLLNSILKQDRVIVSNIAGTTRDAVDVEFSYEGKDFILVDTAGIRRPSNIDYGVE
FFAVNRSLEAIEKSDVCALVIDATEGVSRQDMRLASLVNRKGKGLIVVLNKIDLIKDIEALKKHVDKKLEFVYFAPRVYV
SAKEGINVFSILQKAIDIYEEYSKPIKTSYVNRVVEKILEEYPQNSTKSIKVYYTVFSPKPPTIVLHTNNKDFWREDYLR
FFEKKLREKLNINYAPLNIILKEHQKKEV

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=457, Percent_Identity=33.0415754923414, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI2367268, Length=117, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=115, Percent_Identity=36.5217391304348, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=220, Percent_Identity=32.2727272727273, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48846; Mature: 48846

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIVITGRANVGKSTLFNKISKRRISIVENIPGITRDVIESKAVFQDKVFKLVDTGGLT
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DSKEEISQAIRDKVLKLYKEAYKIIFVVDGKTGLMPEDKDIAKLLYPYKEKVYVAVNKTD
CCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHCCCCCEEEEEEECCC
SKKASASEFYELGFDNVFEISATHGTGVFELLEEITKDLKAMEELEEKADFIKLSFVGKP
CCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
NSGKSSLLNSILKQDRVIVSNIAGTTRDAVDVEFSYEGKDFILVDTAGIRRPSNIDYGVE
CCCHHHHHHHHHHHCCEEEHHCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEE
FFAVNRSLEAIEKSDVCALVIDATEGVSRQDMRLASLVNRKGKGLIVVLNKIDLIKDIEA
EEEECCHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHH
LKKHVDKKLEFVYFAPRVYVSAKEGINVFSILQKAIDIYEEYSKPIKTSYVNRVVEKILE
HHHHHCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EYPQNSTKSIKVYYTVFSPKPPTIVLHTNNKDFWREDYLRFFEKKLREKLNINYAPLNII
HCCCCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LKEHQKKEV
EEHHHCCCC
>Mature Secondary Structure
MEKIVITGRANVGKSTLFNKISKRRISIVENIPGITRDVIESKAVFQDKVFKLVDTGGLT
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DSKEEISQAIRDKVLKLYKEAYKIIFVVDGKTGLMPEDKDIAKLLYPYKEKVYVAVNKTD
CCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHCCCCCEEEEEEECCC
SKKASASEFYELGFDNVFEISATHGTGVFELLEEITKDLKAMEELEEKADFIKLSFVGKP
CCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
NSGKSSLLNSILKQDRVIVSNIAGTTRDAVDVEFSYEGKDFILVDTAGIRRPSNIDYGVE
CCCHHHHHHHHHHHCCEEEHHCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEE
FFAVNRSLEAIEKSDVCALVIDATEGVSRQDMRLASLVNRKGKGLIVVLNKIDLIKDIEA
EEEECCHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHH
LKKHVDKKLEFVYFAPRVYVSAKEGINVFSILQKAIDIYEEYSKPIKTSYVNRVVEKILE
HHHHHCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EYPQNSTKSIKVYYTVFSPKPPTIVLHTNNKDFWREDYLRFFEKKLREKLNINYAPLNII
HCCCCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LKEHQKKEV
EEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]