| Definition | Hydrogenobaculum sp. Y04AAS1 chromosome, complete genome. |
|---|---|
| Accession | NC_011126 |
| Length | 1,559,514 |
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The map label for this gene is mrcA [H]
Identifier: 195952822
GI number: 195952822
Start: 387461
End: 390007
Strand: Direct
Name: mrcA [H]
Synonym: HY04AAS1_0444
Alternate gene names: 195952822
Gene position: 387461-390007 (Clockwise)
Preceding gene: 195952821
Following gene: 195952823
Centisome position: 24.84
GC content: 38.59
Gene sequence:
>2547_bases ATGAAAAACATACTTTCTTTTTTAGGTTTTTTTATAGTTGTTGTATTTGTGCTTTTAGGAGTATATGTTTATAGCGTAAG TATTGGGCTTCCGGACGTGAGAGCCTTAGAGAATTGGCATCCACCAGAAGCGTCAATGGTGTACGACTCAAACGGTAAAC TTATAGGTACGATAGGAGCTCAGAATAGGATTTATGTAACAATAGACAAAATACCTAAAATAGTTCAAGATGCTTTTGTT TCTGCTGAAGATAAGACTTTTTATCACAACATAGGAATAGACCCAACAAGTATAATAAGGGCTTTAATAGTAGATTTAGA AAAGGGAAAGGCTGTAGAAGGCGGAAGCACTATAACCCAGCAACTGGCGAAAAACCTTTTCCTTACCCCTAAGAAGACAA TATCTAGGAAGATAAAAGAAGCAATCCTTGCCATAGAGATAACCCATACTTTTCCCAAAAGCAAAATACTTGAAATGTAT CTCAACCAGATATATTTGGGGCATGGTGCCTTTGGTGTAGAAGCTGCATCGGAAACTTACTTTGGTAAACACGTTTGGCA ACTGGGCCTTGACGAAGCTGCTCTTTTGGCTGGGCTTCCTAGGGCTCCTACAAAGTATGATCCATATATAAATCCAAACT TGGCTCTTCAGAGAAGAAACTACGTTTTGTATAGAATGTATAAAGATGGCTATATTACGAAAGAAGAGTACCTTAAAGCC TCTCAGAAACCTATTGTTTTAAACAAACATACAAACCCCATCACCAATAGCGATTATTTCGTTAGTTTTTTAAAAGATTA TATGTATAGAAATTTTCCCGATCTTATTTATCAAGGTGGATTAAAAATTTATACCACTTTAAATGAAACGCTTCAGCAAG CAGCGGAAAATGCTGTTAGAAACCAAATATTGTATATATCTAAACTAGAACATTATCCAGTTCTACCTTGGTCTATTACC GATACTATAGCAAAATTTAAGGCTCAAAAAATAGATCTTAAGAAATCCAGGTATTATATAGGTTTTGTTAAAAGCATAAA AAATAATCAGGCAAATATAGATATAAACGGCACAGAGGTCACCGCTAAAATTTTCCCCGGTATAAACGCTGGCGAGTACG TAATGGTAGAACTTTCACGCCCCACAAGTATGCCACGATCTACAAGTATGCCACGATCTACAAGTATGCCACGATCTACA AGTATGCCACGATCTACAAGTATGCCACGATCTACAAGTATGCCACGATCTACAAGTATGCCACGCCCCAATAACGGATT TAATGCAAAGATAATACCGCAGCTTCAATCGGCTTTGGTTAGCATGAACGTACATAATGGTGCTATATTGGCTTTGGTGG GTGGATACTCTTATCAGCTTTCTTCTTACAATAGAGCAGTTTATGCTTTAAGACAGACTGGTTCTGCTATAAAACCTATA GTTTACCTATCAGCCTTGATGAAAGGCTATACTCAGATAACCGAGATAGACGCTACGCCTCATGCTTATAAAGATCCATC TGCCCCGGGTGGATTTTGGACACCTAGAAATTATGAGGGAGAGAGTTTTACTACAATTACCTTAAGAAAAGCTTTGGCTT ACAGCGTTAATACTGCGAGCGTAAATCTTTTGGCTCAGGTGGGTTTTGATCTACCAATATCTTTAGCAGCAAGGGTGGGT ATAAAACTTCCTCCATATTATTCTATGGTGCTTGGTAGTACAAGCGTTACTCCGCTTCAACTTACAAACATGTTTCAAGC TTTCGCCAACTTAGGGACTTACTGTGAACCGTATTTTATAACAAAGATAGTAAACTCTCAAAACCAAGTGGTATATACAG GTCATCCAGTTTGCTACAACGTATTCCCAGCTCCTTACGATAGAGTCTTGATATCTATGTTAGAATATGTGGTAAAAGTT GGGACTGGCTATGCTGCCCATGTGTTGGGACCTTATATAGCTGGTAAGACAGGTACTACAAACCATTACGACGATGCTTG GTTTGAGGGCTTTTCCTCTGATGTGGTGACTGGTGTTTGGACTGGGTTTGATATAAGAAAAAGAATAGGCTACAATATGG CTGGTGCTGCAGCATCGCTTCCTACTTGGATAAACTATATGAAAGAAGCACTAAGCATATATCCGGAAAAGCCGTTTCCT TTGCCAGATGGGGTAGAGTATGTGGATATAGACCCAAAAACCTACTTAAGGGCTACCCCTTCTTGTCCTGGAGAACCTAT ACTTTTTGTAAAAGGTACAGCACCAAAAACAACTTGTCAAAACGTTTCCTTGCCGGTTCTTCAAAGTTTAAACCCAAATC AACCGCAAAGCCCCGGAAGTCCTTTGCAGCCTTTAAACAACACTCCCTCATCATCTCAACAACAGTCGTCTCAAGGCACT ATATCACCTACCAAGCCTCCCGCAAACCCTAATTCAAAAAATCCAAATGGCGTATTACCTAAAATAATACAAGAGATAAA CAAAGAAACTTATCAAATAGATAATGAAACGAAAAATATAAATAAGGAGTTAAACAATGCTCGCTAA
Upstream 100 bases:
>100_bases GTTTTGAGCTTTTAGCATATACAAAAGCAAGACCAAAAGGTACCAAAGGAAACGAAGAATTTTTTACTTATTTCATATTA AAGGATTATAATAAGACAAA
Downstream 100 bases:
>100_bases GAGGATTATACCATGTCTTGATATAAAAGATGGTAGGGTAGTAAAAGGTATAAACTTTGTAGATTTGAAAGACGCTGGGG ACCCAGTGGAAAATGCAATT
Product: penicillin-binding protein, 1A family
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 848; Mature: 848
Protein sequence:
>848_residues MKNILSFLGFFIVVVFVLLGVYVYSVSIGLPDVRALENWHPPEASMVYDSNGKLIGTIGAQNRIYVTIDKIPKIVQDAFV SAEDKTFYHNIGIDPTSIIRALIVDLEKGKAVEGGSTITQQLAKNLFLTPKKTISRKIKEAILAIEITHTFPKSKILEMY LNQIYLGHGAFGVEAASETYFGKHVWQLGLDEAALLAGLPRAPTKYDPYINPNLALQRRNYVLYRMYKDGYITKEEYLKA SQKPIVLNKHTNPITNSDYFVSFLKDYMYRNFPDLIYQGGLKIYTTLNETLQQAAENAVRNQILYISKLEHYPVLPWSIT DTIAKFKAQKIDLKKSRYYIGFVKSIKNNQANIDINGTEVTAKIFPGINAGEYVMVELSRPTSMPRSTSMPRSTSMPRST SMPRSTSMPRSTSMPRSTSMPRPNNGFNAKIIPQLQSALVSMNVHNGAILALVGGYSYQLSSYNRAVYALRQTGSAIKPI VYLSALMKGYTQITEIDATPHAYKDPSAPGGFWTPRNYEGESFTTITLRKALAYSVNTASVNLLAQVGFDLPISLAARVG IKLPPYYSMVLGSTSVTPLQLTNMFQAFANLGTYCEPYFITKIVNSQNQVVYTGHPVCYNVFPAPYDRVLISMLEYVVKV GTGYAAHVLGPYIAGKTGTTNHYDDAWFEGFSSDVVTGVWTGFDIRKRIGYNMAGAAASLPTWINYMKEALSIYPEKPFP LPDGVEYVDIDPKTYLRATPSCPGEPILFVKGTAPKTTCQNVSLPVLQSLNPNQPQSPGSPLQPLNNTPSSSQQQSSQGT ISPTKPPANPNSKNPNGVLPKIIQEINKETYQIDNETKNINKELNNAR
Sequences:
>Translated_848_residues MKNILSFLGFFIVVVFVLLGVYVYSVSIGLPDVRALENWHPPEASMVYDSNGKLIGTIGAQNRIYVTIDKIPKIVQDAFV SAEDKTFYHNIGIDPTSIIRALIVDLEKGKAVEGGSTITQQLAKNLFLTPKKTISRKIKEAILAIEITHTFPKSKILEMY LNQIYLGHGAFGVEAASETYFGKHVWQLGLDEAALLAGLPRAPTKYDPYINPNLALQRRNYVLYRMYKDGYITKEEYLKA SQKPIVLNKHTNPITNSDYFVSFLKDYMYRNFPDLIYQGGLKIYTTLNETLQQAAENAVRNQILYISKLEHYPVLPWSIT DTIAKFKAQKIDLKKSRYYIGFVKSIKNNQANIDINGTEVTAKIFPGINAGEYVMVELSRPTSMPRSTSMPRSTSMPRST SMPRSTSMPRSTSMPRSTSMPRPNNGFNAKIIPQLQSALVSMNVHNGAILALVGGYSYQLSSYNRAVYALRQTGSAIKPI VYLSALMKGYTQITEIDATPHAYKDPSAPGGFWTPRNYEGESFTTITLRKALAYSVNTASVNLLAQVGFDLPISLAARVG IKLPPYYSMVLGSTSVTPLQLTNMFQAFANLGTYCEPYFITKIVNSQNQVVYTGHPVCYNVFPAPYDRVLISMLEYVVKV GTGYAAHVLGPYIAGKTGTTNHYDDAWFEGFSSDVVTGVWTGFDIRKRIGYNMAGAAASLPTWINYMKEALSIYPEKPFP LPDGVEYVDIDPKTYLRATPSCPGEPILFVKGTAPKTTCQNVSLPVLQSLNPNQPQSPGSPLQPLNNTPSSSQQQSSQGT ISPTKPPANPNSKNPNGVLPKIIQEINKETYQIDNETKNINKELNNAR >Mature_848_residues MKNILSFLGFFIVVVFVLLGVYVYSVSIGLPDVRALENWHPPEASMVYDSNGKLIGTIGAQNRIYVTIDKIPKIVQDAFV SAEDKTFYHNIGIDPTSIIRALIVDLEKGKAVEGGSTITQQLAKNLFLTPKKTISRKIKEAILAIEITHTFPKSKILEMY LNQIYLGHGAFGVEAASETYFGKHVWQLGLDEAALLAGLPRAPTKYDPYINPNLALQRRNYVLYRMYKDGYITKEEYLKA SQKPIVLNKHTNPITNSDYFVSFLKDYMYRNFPDLIYQGGLKIYTTLNETLQQAAENAVRNQILYISKLEHYPVLPWSIT DTIAKFKAQKIDLKKSRYYIGFVKSIKNNQANIDINGTEVTAKIFPGINAGEYVMVELSRPTSMPRSTSMPRSTSMPRST SMPRSTSMPRSTSMPRSTSMPRPNNGFNAKIIPQLQSALVSMNVHNGAILALVGGYSYQLSSYNRAVYALRQTGSAIKPI VYLSALMKGYTQITEIDATPHAYKDPSAPGGFWTPRNYEGESFTTITLRKALAYSVNTASVNLLAQVGFDLPISLAARVG IKLPPYYSMVLGSTSVTPLQLTNMFQAFANLGTYCEPYFITKIVNSQNQVVYTGHPVCYNVFPAPYDRVLISMLEYVVKV GTGYAAHVLGPYIAGKTGTTNHYDDAWFEGFSSDVVTGVWTGFDIRKRIGYNMAGAAASLPTWINYMKEALSIYPEKPFP LPDGVEYVDIDPKTYLRATPSCPGEPILFVKGTAPKTTCQNVSLPVLQSLNPNQPQSPGSPLQPLNNTPSSSQQQSSQGT ISPTKPPANPNSKNPNGVLPKIIQEINKETYQIDNETKNINKELNNAR
Specific function: Cell Wall Formation. Synthesis Of Cross-Linked Peptidoglycan From The Lipid Intermediates. The Enzyme Has A Penicillin-Insensitive Transglycosylase N-Terminal Domain (Formation Of Linear Glycan Strands) And A Penicillin-Sensitive Transpeptidase C-Terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=309, Percent_Identity=42.3948220064725, Blast_Score=246, Evalue=5e-66, Organism=Escherichia coli, GI1786343, Length=260, Percent_Identity=34.6153846153846, Blast_Score=154, Evalue=2e-38, Organism=Escherichia coli, GI1788867, Length=288, Percent_Identity=30.9027777777778, Blast_Score=119, Evalue=5e-28, Organism=Escherichia coli, GI1789601, Length=166, Percent_Identity=37.3493975903614, Blast_Score=102, Evalue=1e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 94107; Mature: 94107
Theoretical pI: Translated: 9.63; Mature: 9.63
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNILSFLGFFIVVVFVLLGVYVYSVSIGLPDVRALENWHPPEASMVYDSNGKLIGTIGA CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEECCCCCEEEEECC QNRIYVTIDKIPKIVQDAFVSAEDKTFYHNIGIDPTSIIRALIVDLEKGKAVEGGSTITQ CCEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHH QLAKNLFLTPKKTISRKIKEAILAIEITHTFPKSKILEMYLNQIYLGHGAFGVEAASETY HHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHEECCCCCCCCCCCHHH FGKHVWQLGLDEAALLAGLPRAPTKYDPYINPNLALQRRNYVLYRMYKDGYITKEEYLKA HHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCHHHHHHC SQKPIVLNKHTNPITNSDYFVSFLKDYMYRNFPDLIYQGGLKIYTTLNETLQQAAENAVR CCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCEEEEEHHHHHHHHHHHHHHH NQILYISKLEHYPVLPWSITDTIAKFKAQKIDLKKSRYYIGFVKSIKNNQANIDINGTEV HHEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCEEEECCCEE TAKIFPGINAGEYVMVELSRPTSMPRSTSMPRSTSMPRSTSMPRSTSMPRSTSMPRSTSM EEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PRPNNGFNAKIIPQLQSALVSMNVHNGAILALVGGYSYQLSSYNRAVYALRQTGSAIKPI CCCCCCCCCEEHHHHHHHHHHEECCCCEEEEEECCCEEEECCCCHHHHHHHHCCCHHHHH VYLSALMKGYTQITEIDATPHAYKDPSAPGGFWTPRNYEGESFTTITLRKALAYSVNTAS HHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCHH VNLLAQVGFDLPISLAARVGIKLPPYYSMVLGSTSVTPLQLTNMFQAFANLGTYCEPYFI HEEHHHCCCCCCHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHH TKIVNSQNQVVYTGHPVCYNVFPAPYDRVLISMLEYVVKVGTGYAAHVLGPYIAGKTGTT HHHHCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC NHYDDAWFEGFSSDVVTGVWTGFDIRKRIGYNMAGAAASLPTWINYMKEALSIYPEKPFP CCCCCHHHCCCCCCCHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC LPDGVEYVDIDPKTYLRATPSCPGEPILFVKGTAPKTTCQNVSLPVLQSLNPNQPQSPGS CCCCCEEEECCCHHHEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCC PLQPLNNTPSSSQQQSSQGTISPTKPPANPNSKNPNGVLPKIIQEINKETYQIDNETKNI CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHEECCCHHHHH NKELNNAR HHHHCCCC >Mature Secondary Structure MKNILSFLGFFIVVVFVLLGVYVYSVSIGLPDVRALENWHPPEASMVYDSNGKLIGTIGA CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEECCCCCEEEEECC QNRIYVTIDKIPKIVQDAFVSAEDKTFYHNIGIDPTSIIRALIVDLEKGKAVEGGSTITQ CCEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHH QLAKNLFLTPKKTISRKIKEAILAIEITHTFPKSKILEMYLNQIYLGHGAFGVEAASETY HHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHEECCCCCCCCCCCHHH FGKHVWQLGLDEAALLAGLPRAPTKYDPYINPNLALQRRNYVLYRMYKDGYITKEEYLKA HHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCHHHHHHC SQKPIVLNKHTNPITNSDYFVSFLKDYMYRNFPDLIYQGGLKIYTTLNETLQQAAENAVR CCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCEEEEEHHHHHHHHHHHHHHH NQILYISKLEHYPVLPWSITDTIAKFKAQKIDLKKSRYYIGFVKSIKNNQANIDINGTEV HHEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCEEEECCCEE TAKIFPGINAGEYVMVELSRPTSMPRSTSMPRSTSMPRSTSMPRSTSMPRSTSMPRSTSM EEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PRPNNGFNAKIIPQLQSALVSMNVHNGAILALVGGYSYQLSSYNRAVYALRQTGSAIKPI CCCCCCCCCEEHHHHHHHHHHEECCCCEEEEEECCCEEEECCCCHHHHHHHHCCCHHHHH VYLSALMKGYTQITEIDATPHAYKDPSAPGGFWTPRNYEGESFTTITLRKALAYSVNTAS HHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCHH VNLLAQVGFDLPISLAARVGIKLPPYYSMVLGSTSVTPLQLTNMFQAFANLGTYCEPYFI HEEHHHCCCCCCHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHH TKIVNSQNQVVYTGHPVCYNVFPAPYDRVLISMLEYVVKVGTGYAAHVLGPYIAGKTGTT HHHHCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC NHYDDAWFEGFSSDVVTGVWTGFDIRKRIGYNMAGAAASLPTWINYMKEALSIYPEKPFP CCCCCHHHCCCCCCCHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC LPDGVEYVDIDPKTYLRATPSCPGEPILFVKGTAPKTTCQNVSLPVLQSLNPNQPQSPGS CCCCCEEEECCCHHHEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCC PLQPLNNTPSSSQQQSSQGTISPTKPPANPNSKNPNGVLPKIIQEINKETYQIDNETKNI CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHEECCCHHHHH NKELNNAR HHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]