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The map label for this gene is map [H]

Identifier: 195952665

GI number: 195952665

Start: 251827

End: 252600

Strand: Direct

Name: map [H]

Synonym: HY04AAS1_0287

Alternate gene names: 195952665

Gene position: 251827-252600 (Clockwise)

Preceding gene: 195952664

Following gene: 195952666

Centisome position: 16.15

GC content: 37.98

Gene sequence:

>774_bases
ATGATAGAGCTTTATTCAAAATCTGAGATAGAAAAGATAAAAAAAGCTTGTCAAATAGTTAGTGATGTGCTAAAATATAT
AGCTTCTATGGTAAAACCAGGAGTTATAACTTACGATTTGGAAATGGCAGCTAGAGAAAAGACTAAAGAGCTTGGTGGTA
TACCGGCTTTTTTGAATTATCAACCGCCATTTTCCAAAAAAAAATACCCGGCTGCTTTGTGTGTTTCTATAAACGATGAA
GTAGTGCACGGTATTCCATCAAAAACAAAAAAGATAAAGGATGGTGACTTTGTAAGTCTTGATTTTGGCGCTATATACGA
TGGTTATGCAGGTGATGCGGCCATGACGATAGGGGTTGGTAATATTTCTTTAGAAAATCGGAAACTTATTGAGGCTACAA
AAAAGGCGTTATATGAGGCTATCGCACAATGTAAACCGGGAAACTACCTTTATAATATATCTAAAAGCATAGAAACCGTA
GCAAAAGAGTATGGTTTTGGTGTAGTGTGCGAATACGGTGGTCATGGAATAGGTAGAAACAGCCATGAGGAACCTTTTGT
AGCCAATTGTACAGAGGTTATTACTTCTAAAATGAACGCACAGTTAAGGCCTGGTATGGTGATAGCTATAGAACCTATGT
TTACCACTGGTAATGGCGCTGTTTATAAATCAAACGATGGTTGGACTGTAAAAGCAAAAGGTAAGTACGCTTGTCACTTC
GAGCATACGGTAGCTATACTTGAAGACGGTCCTGTAGTGTTAACGGAGTGGTGA

Upstream 100 bases:

>100_bases
CCTTCCCGCTCATAGAGTATTATAAATATAAAAACAAGCTTTTTGTAGTGTCTGCTGATGGTACTCAGGAAGAGGTCTTC
GAAAAACTAAAAAGTATGTT

Downstream 100 bases:

>100_bases
TATGGCAAAGAAGAACAAGAATCAAGAACCGGAAAAAGAAAAGGGTATAGTGTTTGAAGGTGTTATAGAAGAGGCTCTTC
CAAACGCTATGTTTAGAGTT

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIELYSKSEIEKIKKACQIVSDVLKYIASMVKPGVITYDLEMAAREKTKELGGIPAFLNYQPPFSKKKYPAALCVSINDE
VVHGIPSKTKKIKDGDFVSLDFGAIYDGYAGDAAMTIGVGNISLENRKLIEATKKALYEAIAQCKPGNYLYNISKSIETV
AKEYGFGVVCEYGGHGIGRNSHEEPFVANCTEVITSKMNAQLRPGMVIAIEPMFTTGNGAVYKSNDGWTVKAKGKYACHF
EHTVAILEDGPVVLTEW

Sequences:

>Translated_257_residues
MIELYSKSEIEKIKKACQIVSDVLKYIASMVKPGVITYDLEMAAREKTKELGGIPAFLNYQPPFSKKKYPAALCVSINDE
VVHGIPSKTKKIKDGDFVSLDFGAIYDGYAGDAAMTIGVGNISLENRKLIEATKKALYEAIAQCKPGNYLYNISKSIETV
AKEYGFGVVCEYGGHGIGRNSHEEPFVANCTEVITSKMNAQLRPGMVIAIEPMFTTGNGAVYKSNDGWTVKAKGKYACHF
EHTVAILEDGPVVLTEW
>Mature_257_residues
MIELYSKSEIEKIKKACQIVSDVLKYIASMVKPGVITYDLEMAAREKTKELGGIPAFLNYQPPFSKKKYPAALCVSINDE
VVHGIPSKTKKIKDGDFVSLDFGAIYDGYAGDAAMTIGVGNISLENRKLIEATKKALYEAIAQCKPGNYLYNISKSIETV
AKEYGFGVVCEYGGHGIGRNSHEEPFVANCTEVITSKMNAQLRPGMVIAIEPMFTTGNGAVYKSNDGWTVKAKGKYACHF
EHTVAILEDGPVVLTEW

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=257, Percent_Identity=33.0739299610895, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI40385867, Length=256, Percent_Identity=29.296875, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1786364, Length=256, Percent_Identity=37.109375, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1788728, Length=226, Percent_Identity=27.4336283185841, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=260, Percent_Identity=32.6923076923077, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6323273, Length=256, Percent_Identity=36.71875, Blast_Score=154, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24583427, Length=255, Percent_Identity=30.5882352941176, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355531, Length=256, Percent_Identity=32.03125, Blast_Score=130, Evalue=9e-31,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28139; Mature: 28139

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELYSKSEIEKIKKACQIVSDVLKYIASMVKPGVITYDLEMAAREKTKELGGIPAFLNY
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCEEECC
QPPFSKKKYPAALCVSINDEVVHGIPSKTKKIKDGDFVSLDFGAIYDGYAGDAAMTIGVG
CCCCCCCCCCEEEEEEECHHHHCCCCCHHCCCCCCCEEEEECCCEECCCCCCEEEEEEEC
NISLENRKLIEATKKALYEAIAQCKPGNYLYNISKSIETVAKEYGFGVVCEYGGHGIGRN
CEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCCCCC
SHEEPFVANCTEVITSKMNAQLRPGMVIAIEPMFTTGNGAVYKSNDGWTVKAKGKYACHF
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCEEEECCCCEEEEECCCEEEEE
EHTVAILEDGPVVLTEW
EEEEEEEECCCEEEECC
>Mature Secondary Structure
MIELYSKSEIEKIKKACQIVSDVLKYIASMVKPGVITYDLEMAAREKTKELGGIPAFLNY
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCEEECC
QPPFSKKKYPAALCVSINDEVVHGIPSKTKKIKDGDFVSLDFGAIYDGYAGDAAMTIGVG
CCCCCCCCCCEEEEEEECHHHHCCCCCHHCCCCCCCEEEEECCCEECCCCCCEEEEEEEC
NISLENRKLIEATKKALYEAIAQCKPGNYLYNISKSIETVAKEYGFGVVCEYGGHGIGRN
CEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCCCCC
SHEEPFVANCTEVITSKMNAQLRPGMVIAIEPMFTTGNGAVYKSNDGWTVKAKGKYACHF
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCEEEECCCCEEEEECCCEEEEE
EHTVAILEDGPVVLTEW
EEEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]