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The map label for this gene is nuoE [H]

Identifier: 195952595

GI number: 195952595

Start: 195107

End: 195571

Strand: Direct

Name: nuoE [H]

Synonym: HY04AAS1_0215

Alternate gene names: 195952595

Gene position: 195107-195571 (Clockwise)

Preceding gene: 195952594

Following gene: 195952596

Centisome position: 12.51

GC content: 40.43

Gene sequence:

>465_bases
ATGCTAACTCAAGAGATAAAAGAGGCTATAGAAGGTCATATAAAGTATTTTGGGTCTAAGGAAGAGGCTATGCTGCTTTC
TCTTCACTCTATTCAAGAGCACCTTGGCCACATACCAGAAGAGGCTTTGGAAGAGCTCTCAGAGATTTTAGATATACCGC
TTCATCATATAAAAGGTGTGGTGGCTTTTTATGAAATGTTTGACACAGGCGAAAAAGCCAAGCACCGCATATACGTATGC
AATAGCATAGTTTGCTATCTTCTTAAAAGCCACAAAGTTTTCAACGCTGTAAAAGAACTTCTTGGTATAGAGCCAGGCCA
AGTGACAAGAGATGGCATGTTTAAGCTTGTGGAAGTCCAATGCCTTGGTGCTTGCTCAGAAGCACCGGTTTTCATGGTAG
ACAACGATACGTATAGGTATGAATCAAAGGAGAAGCTTCATGAAATACTTGCCAAATATAGCTAA

Upstream 100 bases:

>100_bases
ATAAAGCTCTTTACTACGCAAAAAGAAGCGGTAAAAATCGTATTGAGATTTTGATATAAATTAAGTTGCAAAAATAACTA
TAAAAGCTTAAAATGTATAT

Downstream 100 bases:

>100_bases
TATACACGCTGAAACGGAGCTAAACCTTCTTCTTAAAAGAGCCAAACGCAAGCGAACCGCCGATATAAAAGAATACTTAA
AAGACAATGGATATCTTGCG

Product: NADH-quinone oxidoreductase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MLTQEIKEAIEGHIKYFGSKEEAMLLSLHSIQEHLGHIPEEALEELSEILDIPLHHIKGVVAFYEMFDTGEKAKHRIYVC
NSIVCYLLKSHKVFNAVKELLGIEPGQVTRDGMFKLVEVQCLGACSEAPVFMVDNDTYRYESKEKLHEILAKYS

Sequences:

>Translated_154_residues
MLTQEIKEAIEGHIKYFGSKEEAMLLSLHSIQEHLGHIPEEALEELSEILDIPLHHIKGVVAFYEMFDTGEKAKHRIYVC
NSIVCYLLKSHKVFNAVKELLGIEPGQVTRDGMFKLVEVQCLGACSEAPVFMVDNDTYRYESKEKLHEILAKYS
>Mature_154_residues
MLTQEIKEAIEGHIKYFGSKEEAMLLSLHSIQEHLGHIPEEALEELSEILDIPLHHIKGVVAFYEMFDTGEKAKHRIYVC
NSIVCYLLKSHKVFNAVKELLGIEPGQVTRDGMFKLVEVQCLGACSEAPVFMVDNDTYRYESKEKLHEILAKYS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=151, Percent_Identity=32.4503311258278, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788621, Length=147, Percent_Identity=31.9727891156463, Blast_Score=100, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17561328, Length=151, Percent_Identity=31.7880794701987, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18859877, Length=151, Percent_Identity=33.112582781457, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355353, Length=129, Percent_Identity=34.1085271317829, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17596; Mature: 17596

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTQEIKEAIEGHIKYFGSKEEAMLLSLHSIQEHLGHIPEEALEELSEILDIPLHHIKGV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VAFYEMFDTGEKAKHRIYVCNSIVCYLLKSHKVFNAVKELLGIEPGQVTRDGMFKLVEVQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
CLGACSEAPVFMVDNDTYRYESKEKLHEILAKYS
HHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLTQEIKEAIEGHIKYFGSKEEAMLLSLHSIQEHLGHIPEEALEELSEILDIPLHHIKGV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VAFYEMFDTGEKAKHRIYVCNSIVCYLLKSHKVFNAVKELLGIEPGQVTRDGMFKLVEVQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
CLGACSEAPVFMVDNDTYRYESKEKLHEILAKYS
HHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]