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The map label for this gene is yeiR [H]

Identifier: 195952562

GI number: 195952562

Start: 162944

End: 163870

Strand: Direct

Name: yeiR [H]

Synonym: HY04AAS1_0182

Alternate gene names: 195952562

Gene position: 162944-163870 (Clockwise)

Preceding gene: 195952561

Following gene: 195952563

Centisome position: 10.45

GC content: 30.1

Gene sequence:

>927_bases
ATGATATCTTCTTTTGTAATAACGGGGTTTTTAGGTGCTGGTAAAACTACTTTTATGCTAAAAGCTGTAAAAGAGCATTT
TAAAGATAAAAAAGTAGCTGTTATTGTAAACGAGATTGGTGATGTAGGTGTTGATGGTAAAATACTTCAAAATGTTTATT
CTAACGTGCTTGAGCTTTCAGAGGGTTGTATATGCTGCACTTTGCAGGCGGAGTTTGAAAAAGGCGTTTACGAGATTTTA
GAAAAATACAATCCAGATTTTCTTTTTGTAGAAACCTCTGGAGCTTCAAATCCCTTTCCTATCATGTTAAGCCTTCAAAA
TATAGGTTCTTTGTTAGAAGGTGTTGTATGTGTTGTAGATGCAAAAAATTTTCATAACTATAAATCTAACGAAACTTTTA
AATATCAAATAGGCAGCTCAAATATAATAGTTATAAATAAGATAGATTTGGTATCTGAAAAAGAATTAGAAAATATAGAG
AACGAGGTAAAAGTCATAAAGAAAGAGTATAATCTAAGAGATTTTCTAACCTCAGAAGAATTTTTTAAAGATTTTAAAAT
CTATAAAAGTAAATACGGCCAAGTAGACGAAAATTTGTTTAAACACGTCTATCCTATAAGAGATTTACCAAATCTACCAG
TCAATTTAGCTGGAGTAAACCATCTTGAAGAATCCCATATAGGGGAGTTTGTGGTATTTTTAGAAAAAGAGATATTTTAC
GATGAATTGGAGCAGAAGTTAAAAAATATACCTAAAAATATATACAGGATAAAAGGTATCGTGAGGCTTAAAGATTTTCA
AACTCCTATGGTTGTCAACTATGTGTTTGGTTATACGGAGTTAAGCCCCATAGAAAAATACGATGGTAAGTCTTTTTTAG
TATTTATTGGTGAGAATATCAAAAAAGAAAATGTTTTTGTATTATAA

Upstream 100 bases:

>100_bases
ACGTTATATCTGGAAGCGTTGTCAATACAACTACTGGCAAGGTGCAAGTACCAGATATGAGCAAATTTAACACCACAGAC
AACACTACAAACAATCAGCA

Downstream 100 bases:

>100_bases
TTAATGTATGGGTATATTGTTTGATAAGAAAGATTTTTTGTCGTTGGTGGGATACTCCTTTTCTTTGCTTGGAAGGATAA
ACAAAGAGCTAAGTCTAGCA

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MISSFVITGFLGAGKTTFMLKAVKEHFKDKKVAVIVNEIGDVGVDGKILQNVYSNVLELSEGCICCTLQAEFEKGVYEIL
EKYNPDFLFVETSGASNPFPIMLSLQNIGSLLEGVVCVVDAKNFHNYKSNETFKYQIGSSNIIVINKIDLVSEKELENIE
NEVKVIKKEYNLRDFLTSEEFFKDFKIYKSKYGQVDENLFKHVYPIRDLPNLPVNLAGVNHLEESHIGEFVVFLEKEIFY
DELEQKLKNIPKNIYRIKGIVRLKDFQTPMVVNYVFGYTELSPIEKYDGKSFLVFIGENIKKENVFVL

Sequences:

>Translated_308_residues
MISSFVITGFLGAGKTTFMLKAVKEHFKDKKVAVIVNEIGDVGVDGKILQNVYSNVLELSEGCICCTLQAEFEKGVYEIL
EKYNPDFLFVETSGASNPFPIMLSLQNIGSLLEGVVCVVDAKNFHNYKSNETFKYQIGSSNIIVINKIDLVSEKELENIE
NEVKVIKKEYNLRDFLTSEEFFKDFKIYKSKYGQVDENLFKHVYPIRDLPNLPVNLAGVNHLEESHIGEFVVFLEKEIFY
DELEQKLKNIPKNIYRIKGIVRLKDFQTPMVVNYVFGYTELSPIEKYDGKSFLVFIGENIKKENVFVL
>Mature_308_residues
MISSFVITGFLGAGKTTFMLKAVKEHFKDKKVAVIVNEIGDVGVDGKILQNVYSNVLELSEGCICCTLQAEFEKGVYEIL
EKYNPDFLFVETSGASNPFPIMLSLQNIGSLLEGVVCVVDAKNFHNYKSNETFKYQIGSSNIIVINKIDLVSEKELENIE
NEVKVIKKEYNLRDFLTSEEFFKDFKIYKSKYGQVDENLFKHVYPIRDLPNLPVNLAGVNHLEESHIGEFVVFLEKEIFY
DELEQKLKNIPKNIYRIKGIVRLKDFQTPMVVNYVFGYTELSPIEKYDGKSFLVFIGENIKKENVFVL

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=331, Percent_Identity=24.773413897281, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI146231952, Length=331, Percent_Identity=25.3776435045317, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI148727351, Length=331, Percent_Identity=25.3776435045317, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI33469141, Length=331, Percent_Identity=24.773413897281, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI223941779, Length=327, Percent_Identity=24.4648318042813, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI223941776, Length=321, Percent_Identity=23.98753894081, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI119120938, Length=132, Percent_Identity=32.5757575757576, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788499, Length=223, Percent_Identity=30.4932735426009, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082430, Length=168, Percent_Identity=32.7380952380952, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324356, Length=177, Percent_Identity=29.9435028248588, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 35299; Mature: 35299

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSFVITGFLGAGKTTFMLKAVKEHFKDKKVAVIVNEIGDVGVDGKILQNVYSNVLELS
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHC
EGCICCTLQAEFEKGVYEILEKYNPDFLFVETSGASNPFPIMLSLQNIGSLLEGVVCVVD
CCCEEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHCEEEEEE
AKNFHNYKSNETFKYQIGSSNIIVINKIDLVSEKELENIENEVKVIKKEYNLRDFLTSEE
CCCCCCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCHHH
FFKDFKIYKSKYGQVDENLFKHVYPIRDLPNLPVNLAGVNHLEESHIGEFVVFLEKEIFY
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
DELEQKLKNIPKNIYRIKGIVRLKDFQTPMVVNYVFGYTELSPIEKYDGKSFLVFIGENI
HHHHHHHHHCCHHHHHHHHEEEEECCCCCEEEHEECCCCCCCCHHHCCCCEEEEEECCCC
KKENVFVL
CCCCEEEC
>Mature Secondary Structure
MISSFVITGFLGAGKTTFMLKAVKEHFKDKKVAVIVNEIGDVGVDGKILQNVYSNVLELS
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHC
EGCICCTLQAEFEKGVYEILEKYNPDFLFVETSGASNPFPIMLSLQNIGSLLEGVVCVVD
CCCEEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHCEEEEEE
AKNFHNYKSNETFKYQIGSSNIIVINKIDLVSEKELENIENEVKVIKKEYNLRDFLTSEE
CCCCCCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCHHH
FFKDFKIYKSKYGQVDENLFKHVYPIRDLPNLPVNLAGVNHLEESHIGEFVVFLEKEIFY
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
DELEQKLKNIPKNIYRIKGIVRLKDFQTPMVVNYVFGYTELSPIEKYDGKSFLVFIGENI
HHHHHHHHHCCHHHHHHHHEEEEECCCCCEEEHEECCCCCCCCHHHCCCCEEEEEECCCC
KKENVFVL
CCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]