Definition Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome.
Accession NC_011094
Length 4,709,075

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The map label for this gene is idnO [H]

Identifier: 194737794

GI number: 194737794

Start: 4603226

End: 4603990

Strand: Reverse

Name: idnO [H]

Synonym: SeSA_A4738

Alternate gene names: 194737794

Gene position: 4603990-4603226 (Counterclockwise)

Preceding gene: 194734309

Following gene: 194734465

Centisome position: 97.77

GC content: 53.46

Gene sequence:

>765_bases
ATGAACGATCTTTTTTCACTGGCAGGTAAAAATATCCTTATCACCGGAGCCGCTCAGGGAATTGGTTATTTGCTGGCAAC
CGGTCTTGGTCGCTATGGCGCGCGCATTATTGTTAACGATATTACCCCGGAGCGCGCCGAAACAGCCGTGACGAAACTTC
AGCAGGAAGGGATAAAGGCTATTGCCGCTCCCTTTAATGTCACCCATAAACAGGATATTGAAGCTGCGGTTGAACATATC
GAAAAAGATATCGGCGTCATTGACGTCCTGATAAATAACGCCGGTATCCAGCGCCGTCATCCGTTTACTGAGTTTCCCGA
GCAGGAGTGGAATGACGTCATCGCCGTAAATCAGACCGCGGTTTTTCTCGTCTCTCAGGCCGTTACGCGCCGTATGGTGG
CGCGGCAGGCAGGAAAAGTGATCAACATCTGTTCGATGCAAAGCGAGCTGGGCCGCGACACGATTACGCCATACGCCGCG
TCGAAGGGTGCCGTGAAGATGCTGACTCGCGGCATGTGCGTGGAGCTGGCGCGTCATAATATCCAGGTCAACGGTATTGC
GCCGGGATACTTCAAAACGGAGATGACCAAAGCGCTGGTTGAAGATGAAGCCTTCACCTCCTGGCTATGCAAACGTACGC
CTGCCGCACGCTGGGGCGATCCCCAGGAGCTTATTGGCGCAGCGGTGTTTCTCTCGTCAAAAGCCTCCGACTTTGTTAAC
GGACATCTGCTGTTTGTCGATGGCGGTATGCTGGTTGCCGTCTGA

Upstream 100 bases:

>100_bases
ATTTACCGACCTGGAAGCGGCGCTGATCTTTGCCGGAGACAAAACACAGGCGGCAAAAGTTCAGCTCGTTTTCTGAGAAA
GTAAAATAAGGGACACTATC

Downstream 100 bases:

>100_bases
CCAGGGAAATACGACGCAGCGCGTAAGCGCTGCTATTTTGGCGCTAATAAGAGAGACGAATATGCCATTAATAATTATTG
CGGCAGGCGTTGCGCTGCTG

Product: gluconate 5-dehydrogenase

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MNDLFSLAGKNILITGAAQGIGYLLATGLGRYGARIIVNDITPERAETAVTKLQQEGIKAIAAPFNVTHKQDIEAAVEHI
EKDIGVIDVLINNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRRMVARQAGKVINICSMQSELGRDTITPYAA
SKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTSWLCKRTPAARWGDPQELIGAAVFLSSKASDFVN
GHLLFVDGGMLVAV

Sequences:

>Translated_254_residues
MNDLFSLAGKNILITGAAQGIGYLLATGLGRYGARIIVNDITPERAETAVTKLQQEGIKAIAAPFNVTHKQDIEAAVEHI
EKDIGVIDVLINNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRRMVARQAGKVINICSMQSELGRDTITPYAA
SKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTSWLCKRTPAARWGDPQELIGAAVFLSSKASDFVN
GHLLFVDGGMLVAV
>Mature_254_residues
MNDLFSLAGKNILITGAAQGIGYLLATGLGRYGARIIVNDITPERAETAVTKLQQEGIKAIAAPFNVTHKQDIEAAVEHI
EKDIGVIDVLINNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRRMVARQAGKVINICSMQSELGRDTITPYAA
SKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTSWLCKRTPAARWGDPQELIGAAVFLSSKASDFVN
GHLLFVDGGMLVAV

Specific function: Catalyzes a reversible reduction of 5-ketoglutanate to form D-gluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=32.0675105485232, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=30.7692307692308, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=31.8548387096774, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=29.718875502008, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=29.1497975708502, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=26.8, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=28.3400809716599, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=28.1632653061224, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=31.2775330396476, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=29.2, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI4504505, Length=232, Percent_Identity=27.1551724137931, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=29.5918367346939, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=30.2197802197802, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI210032110, Length=195, Percent_Identity=24.6153846153846, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=27.8350515463918, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=26.9430051813472, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503301, Length=199, Percent_Identity=25.6281407035176, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI4503817, Length=206, Percent_Identity=23.7864077669903, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=25.2631578947368, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI209862901, Length=205, Percent_Identity=26.3414634146341, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI19923983, Length=205, Percent_Identity=26.3414634146341, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=27.7992277992278, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI142976729, Length=181, Percent_Identity=24.3093922651934, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI310128830, Length=211, Percent_Identity=23.2227488151659, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI310115468, Length=211, Percent_Identity=23.2227488151659, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI109715829, Length=191, Percent_Identity=28.2722513089005, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI226371731, Length=199, Percent_Identity=27.1356783919598, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=92.1259842519685, Blast_Score=490, Evalue=1e-140,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=39.2, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=41.3654618473896, Blast_Score=180, Evalue=6e-47,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=34.9593495934959, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=34.8, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=35.4838709677419, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=31.6872427983539, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=30.4526748971193, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=25.4980079681275, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=23.3201581027668, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=25.609756097561, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=191, Percent_Identity=29.3193717277487, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=32.520325203252, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=31.8367346938775, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17560676, Length=239, Percent_Identity=26.7782426778243, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=31.2252964426877, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=27.5303643724696, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193203117, Length=194, Percent_Identity=25.2577319587629, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=25.9259259259259, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=28.9156626506024, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=26.9430051813472, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=25.2918287937743, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=26.0536398467433, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=255, Percent_Identity=25.4901960784314, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=26.0223048327138, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=28.8973384030418, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=27.8625954198473, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=25.8687258687259, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=24.9056603773585, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=24.904214559387, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=24.2424242424242, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=24.3027888446215, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=254, Percent_Identity=25.5905511811024, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555612, Length=217, Percent_Identity=27.6497695852535, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=198, Percent_Identity=26.2626262626263, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=23.6220472440945, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=256, Percent_Identity=26.171875, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=27.1698113207547, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=24.5210727969349, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=24.904214559387, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193210355, Length=196, Percent_Identity=26.0204081632653, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=255, Percent_Identity=25.0980392156863, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=23.4200743494424, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=24.0601503759398, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997099, Length=238, Percent_Identity=26.890756302521, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=22.3938223938224, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=28.4974093264249, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=31.0880829015544, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=31.3131313131313, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=25.9842519685039, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320089, Length=199, Percent_Identity=29.6482412060301, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=33.1983805668016, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=32.0158102766798, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=30.1204819277108, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=24.5967741935484, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=29.3172690763052, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=28.2868525896414, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24640492, Length=193, Percent_Identity=28.4974093264249, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=28.1746031746032, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=27.8884462151394, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364892, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24584744, Length=195, Percent_Identity=29.2307692307692, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=29.2307692307692, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=30.2083333333333, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581726, Length=196, Percent_Identity=28.0612244897959, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18859837, Length=206, Percent_Identity=28.6407766990291, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=28.3505154639175, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=29.1338582677165, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21357673, Length=234, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 27580; Mature: 27580

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNDLFSLAGKNILITGAAQGIGYLLATGLGRYGARIIVNDITPERAETAVTKLQQEGIKA
CCCHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
IAAPFNVTHKQDIEAAVEHIEKDIGVIDVLINNAGIQRRHPFTEFPEQEWNDVIAVNQTA
HHCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHCCCEEEECHHH
VFLVSQAVTRRMVARQAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHN
HHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
IQVNGIAPGYFKTEMTKALVEDEAFTSWLCKRTPAARWGDPQELIGAAVFLSSKASDFVN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHC
GHLLFVDGGMLVAV
CEEEEEECCEEEEC
>Mature Secondary Structure
MNDLFSLAGKNILITGAAQGIGYLLATGLGRYGARIIVNDITPERAETAVTKLQQEGIKA
CCCHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
IAAPFNVTHKQDIEAAVEHIEKDIGVIDVLINNAGIQRRHPFTEFPEQEWNDVIAVNQTA
HHCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHCCCEEEECHHH
VFLVSQAVTRRMVARQAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHN
HHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
IQVNGIAPGYFKTEMTKALVEDEAFTSWLCKRTPAARWGDPQELIGAAVFLSSKASDFVN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHC
GHLLFVDGGMLVAV
CEEEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]