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The map label for this gene is idnT [H]

Identifier: 194734465

GI number: 194734465

Start: 4601845

End: 4603164

Strand: Reverse

Name: idnT [H]

Synonym: SeSA_A4737

Alternate gene names: 194734465

Gene position: 4603164-4601845 (Counterclockwise)

Preceding gene: 194737794

Following gene: 194736291

Centisome position: 97.75

GC content: 52.35

Gene sequence:

>1320_bases
ATGCCATTAATAATTATTGCGGCAGGCGTTGCGCTGCTGTTGGTCTTAATGATTGGCTTTAAAGTTAACGGCTTTATCGC
CCTTGTTCTGGTTGCCGCCGTGGTGGGATTTGCCGAAGGGATGGGCGCGCAAGACGCCCTGCACTCCATACAAAACGGAA
TTGGCGGTACTCTGGGCGGACTCGCCATGATCCTCGGTTTTGGCGCGATGCTGGGAAGATTAATTTCCGACACCGGCGCA
GCGCAGCGCATTGCGACGACGCTCATTAATACGTTCGGCAAAAAACGCGTGCAATGGGCGCTGGTGATCACCGGGCTTAT
CGTCGGCCTGGCAATGTTTTTTGAAGTCGGGTTCGTACTGCTGTTGCCGCTCGTTTTTACGATTGTGGCCTCATCGGGAC
TGCCCTTGCTGTATGTCGGGGTTCCAATGGTCGCCGCCTTATCCGTTACGCACTGCTTCCTGCCGCCGCATCCCGGCCCT
ACCGCTATTGCGACAATTTTTGAGGCAAATCTCGGTACGACCCTGCTGTATGGGTTAATCATTACCATACCGACAGTGAT
TGTTGCCGGCCCTCTGTTTTCAAAATTACTGGCGCGATTTGAAAAAGCGCCGCCTGAAGGATTATTTAATCCTCACCTAT
TCAGTGAAGAAGAGATGCCGTCATTCTGGAACAGTATTTTTGCCGCCGTGATCCCGGTCATTCTGATGGCCATCGCAGCG
GTATGTGAAATCACGCTGCCAAAAACGAATGCCGTGCGGGTTTTCTTCGAATTTATCGGTAATCCAGCAGTGGCGTTGTT
TATTGCCATTATCATCGCCATTTTTACGCTGGGGCGACGCAATGGACGTACGGTTGAGCAGGTGATGGATATCGTCGGCG
AGTCCATTGGCGCTATTGCGATGATTGTTTTTATCATCGCGGGCGGCGGCGCGTTTAAACAAGTGCTGGTGGATAGCGGC
GTGGGCCAATATATCTCGCAATTAATGACCGGCACATCGCTATCTCCGTTATTAATGTGCTGGACGGTAGCCGCCGTGCT
GCGTATTGCGTTAGGTTCCGCGACCGTGGCTGCGATAACCACAGCGGGCGTCGTATTGCCGATTATTAACGTAACCCACG
CCGATCCGGCGTTAATGGTACTGGCGACAGGCGCGGGAAGCGTTATTGCATCACATGTTAACGATCCCGGTTTTTGGCTG
TTTAAAGGGTATTTTAATCTTAGCGTCGGGGAAACCCTACGCACCTGGACCGTTATGGAAACATTGATTTCTGTCATGGG
GTTGCTGGGCGTACTGGCGCTGAATGCGGTTCTGCATTAA

Upstream 100 bases:

>100_bases
CTGCTGTTTGTCGATGGCGGTATGCTGGTTGCCGTCTGACCAGGGAAATACGACGCAGCGCGTAAGCGCTGCTATTTTGG
CGCTAATAAGAGAGACGAAT

Downstream 100 bases:

>100_bases
TTCATCATCCGCAGCCCAATTAACCATGGGGGCGACGTTCCCGCCCCCGGTACTGGAGAAAACATGAGGAATCACAGAAT
TTCTTTGCAGGATATCGCTA

Product: transporter gluconate:H+ symporter (GntP) family protein

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: L-Ido transporter; 5-keto-D-gluconate transporter [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MPLIIIAAGVALLLVLMIGFKVNGFIALVLVAAVVGFAEGMGAQDALHSIQNGIGGTLGGLAMILGFGAMLGRLISDTGA
AQRIATTLINTFGKKRVQWALVITGLIVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGP
TAIATIFEANLGTTLLYGLIITIPTVIVAGPLFSKLLARFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAA
VCEITLPKTNAVRVFFEFIGNPAVALFIAIIIAIFTLGRRNGRTVEQVMDIVGESIGAIAMIVFIIAGGGAFKQVLVDSG
VGQYISQLMTGTSLSPLLMCWTVAAVLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWL
FKGYFNLSVGETLRTWTVMETLISVMGLLGVLALNAVLH

Sequences:

>Translated_439_residues
MPLIIIAAGVALLLVLMIGFKVNGFIALVLVAAVVGFAEGMGAQDALHSIQNGIGGTLGGLAMILGFGAMLGRLISDTGA
AQRIATTLINTFGKKRVQWALVITGLIVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGP
TAIATIFEANLGTTLLYGLIITIPTVIVAGPLFSKLLARFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAA
VCEITLPKTNAVRVFFEFIGNPAVALFIAIIIAIFTLGRRNGRTVEQVMDIVGESIGAIAMIVFIIAGGGAFKQVLVDSG
VGQYISQLMTGTSLSPLLMCWTVAAVLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWL
FKGYFNLSVGETLRTWTVMETLISVMGLLGVLALNAVLH
>Mature_438_residues
PLIIIAAGVALLLVLMIGFKVNGFIALVLVAAVVGFAEGMGAQDALHSIQNGIGGTLGGLAMILGFGAMLGRLISDTGAA
QRIATTLINTFGKKRVQWALVITGLIVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPT
AIATIFEANLGTTLLYGLIITIPTVIVAGPLFSKLLARFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAV
CEITLPKTNAVRVFFEFIGNPAVALFIAIIIAIFTLGRRNGRTVEQVMDIVGESIGAIAMIVFIIAGGGAFKQVLVDSGV
GQYISQLMTGTSLSPLLMCWTVAAVLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLF
KGYFNLSVGETLRTWTVMETLISVMGLLGVLALNAVLH

Specific function: Transports L-idonate, D-gluconate and 5-keto-D- gluconate, from the periplasm across the inner membrane [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1790716, Length=439, Percent_Identity=94.3052391799544, Blast_Score=818, Evalue=0.0,
Organism=Escherichia coli, GI48994935, Length=438, Percent_Identity=61.8721461187215, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI2367370, Length=449, Percent_Identity=48.5523385300668, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1790776, Length=435, Percent_Identity=40.4597701149425, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI48994939, Length=439, Percent_Identity=36.9020501138952, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1788707, Length=435, Percent_Identity=33.5632183908046, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1789097, Length=439, Percent_Identity=32.8018223234624, Blast_Score=211, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 45859; Mature: 45728

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLIIIAAGVALLLVLMIGFKVNGFIALVLVAAVVGFAEGMGAQDALHSIQNGIGGTLGG
CCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
LAMILGFGAMLGRLISDTGAAQRIATTLINTFGKKRVQWALVITGLIVGLAMFFEVGFVL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGLI
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHH
ITIPTVIVAGPLFSKLLARFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VCEITLPKTNAVRVFFEFIGNPAVALFIAIIIAIFTLGRRNGRTVEQVMDIVGESIGAIA
HHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
MIVFIIAGGGAFKQVLVDSGVGQYISQLMTGTSLSPLLMCWTVAAVLRIALGSATVAAIT
HHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
TAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLSVGETLRTWTVME
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
TLISVMGLLGVLALNAVLH
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLIIIAAGVALLLVLMIGFKVNGFIALVLVAAVVGFAEGMGAQDALHSIQNGIGGTLGG
CEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
LAMILGFGAMLGRLISDTGAAQRIATTLINTFGKKRVQWALVITGLIVGLAMFFEVGFVL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGLI
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHH
ITIPTVIVAGPLFSKLLARFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VCEITLPKTNAVRVFFEFIGNPAVALFIAIIIAIFTLGRRNGRTVEQVMDIVGESIGAIA
HHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
MIVFIIAGGGAFKQVLVDSGVGQYISQLMTGTSLSPLLMCWTVAAVLRIALGSATVAAIT
HHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
TAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLSVGETLRTWTVME
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
TLISVMGLLGVLALNAVLH
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]