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The map label for this gene is fimC [H]

Identifier: 194737410

GI number: 194737410

Start: 1244737

End: 1245414

Strand: Reverse

Name: fimC [H]

Synonym: SeSA_A1272

Alternate gene names: 194737410

Gene position: 1245414-1244737 (Counterclockwise)

Preceding gene: 194735681

Following gene: 194737765

Centisome position: 26.45

GC content: 49.85

Gene sequence:

>678_bases
ATGAATAAATATAGTTTACTCACTGCCGCCACGCTTATATTCACTACGGCAACCGTACAGGCCGGTGTTATTATCGGCGG
AACCCGTATTATTTATAACGGCGATAAAAAAGAAACGTCGATTAGCGTTAAAAATCCGGACCAATCTTCTTATCTCATTC
AGTCATGGAGTGACGCCGGGGAAAAAAGCAGCGATAAATCGCCGTTTATGGTCACGCCGCCGCTTTTTCGTTTAGGCGCA
GGGCAGGAAAATAATCTGCGAATTCTCCGTACTGGCGGCAATTTGCCGGAAGATCGTGAGTCCCTCTACTGGATGAATAT
TAAGTCGATCCCATCGACGACAGAAAAGCAGGATAACGTTAACACTCTGCAAATTGCGGTGAAAACCCGCATTAAATTAA
TTTACCGTCCGCAGGCGTTGACGGAGCAACCGGAAAACGTCACCGCGAAGCTGACCTGGCAGCACAGCGGTAACCGTCTT
ACCGTGACCAATCCCACAGCCTACTACATGAACTTCAGCACGGTGAAGATAGGAACCAGCACCGTGAAAGACGCTACCTA
TGTCGCGCCGATGAGTTCCGCCAGCTTTACCGCGCCCGCCGAAGCCAGCGGCGACGTAACCTGGACACTTATTAACGATT
TCGGCTCTATCGGGTCTGAACACCACACACGCCTGTAA

Upstream 100 bases:

>100_bases
TAACTTTACCCTGACCTACAACTAATCGCGCGGAATTTATTCTCTCGTTTTAGTAAACCAATAAAGCCGGATGGACCCGG
CTTTGCTTTGGAGATACTCC

Downstream 100 bases:

>100_bases
GACCACACCGAAAGGATATCGGGATGAATGCAGACGCATACAAAAAAATAATGACGCTCAGTCGAATCGCCTGCTTTATC
GCCCTGCAGTGCGCACTGCC

Product: chaperone protein FimC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MNKYSLLTAATLIFTTATVQAGVIIGGTRIIYNGDKKETSISVKNPDQSSYLIQSWSDAGEKSSDKSPFMVTPPLFRLGA
GQENNLRILRTGGNLPEDRESLYWMNIKSIPSTTEKQDNVNTLQIAVKTRIKLIYRPQALTEQPENVTAKLTWQHSGNRL
TVTNPTAYYMNFSTVKIGTSTVKDATYVAPMSSASFTAPAEASGDVTWTLINDFGSIGSEHHTRL

Sequences:

>Translated_225_residues
MNKYSLLTAATLIFTTATVQAGVIIGGTRIIYNGDKKETSISVKNPDQSSYLIQSWSDAGEKSSDKSPFMVTPPLFRLGA
GQENNLRILRTGGNLPEDRESLYWMNIKSIPSTTEKQDNVNTLQIAVKTRIKLIYRPQALTEQPENVTAKLTWQHSGNRL
TVTNPTAYYMNFSTVKIGTSTVKDATYVAPMSSASFTAPAEASGDVTWTLINDFGSIGSEHHTRL
>Mature_225_residues
MNKYSLLTAATLIFTTATVQAGVIIGGTRIIYNGDKKETSISVKNPDQSSYLIQSWSDAGEKSSDKSPFMVTPPLFRLGA
GQENNLRILRTGGNLPEDRESLYWMNIKSIPSTTEKQDNVNTLQIAVKTRIKLIYRPQALTEQPENVTAKLTWQHSGNRL
TVTNPTAYYMNFSTVKIGTSTVKDATYVAPMSSASFTAPAEASGDVTWTLINDFGSIGSEHHTRL

Specific function: Required for the biogenesis of type 1 fimbriae. Binds and interact with fimH [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1790771, Length=217, Percent_Identity=41.9354838709677, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1789532, Length=227, Percent_Identity=37.0044052863436, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1786743, Length=214, Percent_Identity=35.5140186915888, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787171, Length=205, Percent_Identity=37.5609756097561, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786333, Length=239, Percent_Identity=33.4728033472803, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788428, Length=217, Percent_Identity=32.258064516129, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87081806, Length=234, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788677, Length=200, Percent_Identity=34.5, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786936, Length=219, Percent_Identity=31.9634703196347, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI87082203, Length=233, Percent_Identity=27.8969957081545, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 24742; Mature: 24742

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYSLLTAATLIFTTATVQAGVIIGGTRIIYNGDKKETSISVKNPDQSSYLIQSWSDAG
CCCHHHHHHHHHHHHHHHEECCEEEECEEEEECCCCCCEEEEEECCCCCCCEEEECCCCC
EKSSDKSPFMVTPPLFRLGAGQENNLRILRTGGNLPEDRESLYWMNIKSIPSTTEKQDNV
CCCCCCCCEEECCCHHEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCC
NTLQIAVKTRIKLIYRPQALTEQPENVTAKLTWQHSGNRLTVTNPTAYYMNFSTVKIGTS
EEEEEEEEEEEEEEECCHHHCCCCCCEEEEEEEEECCCEEEEECCEEEEEEEEEEEECCC
TVKDATYVAPMSSASFTAPAEASGDVTWTLINDFGSIGSEHHTRL
CCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNKYSLLTAATLIFTTATVQAGVIIGGTRIIYNGDKKETSISVKNPDQSSYLIQSWSDAG
CCCHHHHHHHHHHHHHHHEECCEEEECEEEEECCCCCCEEEEEECCCCCCCEEEECCCCC
EKSSDKSPFMVTPPLFRLGAGQENNLRILRTGGNLPEDRESLYWMNIKSIPSTTEKQDNV
CCCCCCCCEEECCCHHEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCC
NTLQIAVKTRIKLIYRPQALTEQPENVTAKLTWQHSGNRLTVTNPTAYYMNFSTVKIGTS
EEEEEEEEEEEEEEECCHHHCCCCCCEEEEEEEEECCCEEEEECCEEEEEEEEEEEECCC
TVKDATYVAPMSSASFTAPAEASGDVTWTLINDFGSIGSEHHTRL
CCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]