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The map label for this gene is bioC [H]

Identifier: 194737115

GI number: 194737115

Start: 918479

End: 919234

Strand: Direct

Name: bioC [H]

Synonym: SeSA_A0946

Alternate gene names: 194737115

Gene position: 918479-919234 (Clockwise)

Preceding gene: 194734987

Following gene: 194736665

Centisome position: 19.5

GC content: 59.92

Gene sequence:

>756_bases
ATGGCGCAGGTGAATAAGCAGGCTATTGCGGCGGCGTTTGGCCGGGCCGCATCGCAATATGAACAACACGCCTCTTTGCA
GCAACACAGCGCGGATGCGCTACTGACGCTGTTGGCAGGCCGCCAGTTTGCCAGTGTGTTGGACGCAGGCTGCGGCCCTG
GACGTATGAGTCGTTACTGGCGAGAGCGGGGGAGCGAAGTGACCGCCCTGGATCTTTCGCTGGCGATGCTGCAACAGGCG
CGCGATCGTCAGGCGGCGCATCACTATTTGCTGGCGGATATCGAAGCGATTCCCCATGACGCCGAAGTTTTTGACCTGGC
CTGGAGCAACCTGGCGGTCCAGTGGTGCGGCGATTTACGTGATGCGTTGAGCGAGTTGTATCGGGTTGTACGGCCCGGCG
GCGTGGTGGCGTTTACCACCTTGTGCCAGGGGTCGTTGCCGGAGCTGCGTCAGGCATGGCAGGCCGTCGATAATCGCGCT
CACGCGAATAGCTTTTTGCCGGAAGAGGCCATTGACCACGCGCTGCGCGGCTGGCGGGCGTCTCGTCATACTCAGGCGAT
GACATTGTGGTTTGAGGATGCCCTGAGTGCGATGCGCTCGCTTAAAGGCATTGGCGCCACCCATCTTCATGAAGGGCGGG
AGTCGGATGTATTAACCCGCGCCCGGCTTAGACAGATTCAACTGGCATGGCCGCAGCGGCAGGGGAAATATCCGCTGACG
TACCATCTTTTTATGGGAGTGATTGAACGTGACTAA

Upstream 100 bases:

>100_bases
ATTCGTCCGCCGACGGTGCCTGTCGGTACGGCGCGCCTGCGCTTAACGTTAACGCAGGCGCATGAAGCGTGCGATATAGA
CCGTCTGCTGGAGGTGCTGC

Downstream 100 bases:

>100_bases
ACGCTATTTTGTGACCGGTACTGATACTGAAGTCGGTAAAACGGTTGCCAGTTGCGCCTTATTGCAGGCCGCAACGCAGT
TAGGTTATCAAACCGTAGGC

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAQVNKQAIAAAFGRAASQYEQHASLQQHSADALLTLLAGRQFASVLDAGCGPGRMSRYWRERGSEVTALDLSLAMLQQA
RDRQAAHHYLLADIEAIPHDAEVFDLAWSNLAVQWCGDLRDALSELYRVVRPGGVVAFTTLCQGSLPELRQAWQAVDNRA
HANSFLPEEAIDHALRGWRASRHTQAMTLWFEDALSAMRSLKGIGATHLHEGRESDVLTRARLRQIQLAWPQRQGKYPLT
YHLFMGVIERD

Sequences:

>Translated_251_residues
MAQVNKQAIAAAFGRAASQYEQHASLQQHSADALLTLLAGRQFASVLDAGCGPGRMSRYWRERGSEVTALDLSLAMLQQA
RDRQAAHHYLLADIEAIPHDAEVFDLAWSNLAVQWCGDLRDALSELYRVVRPGGVVAFTTLCQGSLPELRQAWQAVDNRA
HANSFLPEEAIDHALRGWRASRHTQAMTLWFEDALSAMRSLKGIGATHLHEGRESDVLTRARLRQIQLAWPQRQGKYPLT
YHLFMGVIERD
>Mature_250_residues
AQVNKQAIAAAFGRAASQYEQHASLQQHSADALLTLLAGRQFASVLDAGCGPGRMSRYWRERGSEVTALDLSLAMLQQAR
DRQAAHHYLLADIEAIPHDAEVFDLAWSNLAVQWCGDLRDALSELYRVVRPGGVVAFTTLCQGSLPELRQAWQAVDNRAH
ANSFLPEEAIDHALRGWRASRHTQAMTLWFEDALSAMRSLKGIGATHLHEGRESDVLTRARLRQIQLAWPQRQGKYPLTY
HLFMGVIERD

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=251, Percent_Identity=70.1195219123506, Blast_Score=340, Evalue=4e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 28093; Mature: 27962

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCC
>Mature Secondary Structure 
AQVNKQAIAAAFGRAASQYEQHASLQQHSADALLTLLAGRQFASVLDAGCGPGRMSRYW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RERGSEVTALDLSLAMLQQARDRQAAHHYLLADIEAIPHDAEVFDLAWSNLAVQWCGDLR
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DALSELYRVVRPGGVVAFTTLCQGSLPELRQAWQAVDNRAHANSFLPEEAIDHALRGWRA
HHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SRHTQAMTLWFEDALSAMRSLKGIGATHLHEGRESDVLTRARLRQIQLAWPQRQGKYPLT
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHH
YHLFMGVIERD
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3058702; 9278503 [H]