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The map label for this gene is dgoD [H]

Identifier: 194736491

GI number: 194736491

Start: 3916963

End: 3918153

Strand: Direct

Name: dgoD [H]

Synonym: SeSA_A4045

Alternate gene names: 194736491

Gene position: 3916963-3918153 (Clockwise)

Preceding gene: 194736132

Following gene: 194735080

Centisome position: 83.18

GC content: 52.98

Gene sequence:

>1191_bases
ATGAAAATTACCAGCGTTGATATTATTGATGTGGCGAACGATTTTGCGTCCGCCACCAGCAAATGGCGTCCGGTGGTGGT
AAAAATTAATACCGACGAAGGCATTTCCGGTTTTGGCGAAGTCGGGCTGGCTTACGGCGTCGGCGCCTCTGCGGGCATCG
GCATGGCAAAAGATTTAGCCGCCATTATCATCGGCATGGACCCGATGAATAACGAAGCTATCTGGGAAAAGATGCTCAAA
AAAACCTTCTGGGGGCAGGGCGGCGGCGGCATCTTTTCCGCGGCGATGAGCGGCATCGATATCGCGCTGTGGGATATCAA
AGGCAAAGCATGGGGCGTACCGCTGTATAAAATGCTTGGCGGCAAAAGCCGCGAGAAAATCAGAACCTACGCCAGTCAGC
TACAGTTTGATTGGGGGGACGGCAGCGATAAAGATATGCTGACCGAGCCGGAGCAGTATGCACAGGCGGCGCTGACCGCC
GTCAGCGAAGGCTATGACGCAATAAAAGTGGATACCGTCGCAATGGATCGCCACGGCAACTGGAACCAGCAAAACCTCAA
CGGGCCTCTCACCGATAAAATCCTTCGTCTGGGCTACGACCGTATGGCCGCCATTCGTGATGCGGTCGGCCCGGACGTGG
ATATCATCGCCGAAATGCACGCCTTTACGGATACTACATCCGCAATTCAGTTTGGTCGCATGATAGAAGAACTGGGTATT
TTCTACTACGAAGAACCAGTCATGCCATTAAACCCCGGACAAATGAAACAAGTGGCTGATAAAGTTAATATTCCACTGGC
GGCTGGCGAACGCATTTACTGGCGCTGGGGATACCGTCCTTTCCTGGAAAACGGCAGCCTGAGCGTTATTCAGCCCGATA
TCTGCACCTGCGGCGGCATCACCGAAGTGAAGAAAATCTGCGATATGGCGCACGTTTACGACAAAACGGTGCAAATCCAC
GTTTGCGGCGGGCCGATTTCCACGGCGGTGGCGCTGCATATGGAAACCGCAATCCCCAACTTCGTCATCCACGAACTGCA
CCGGTATGCGCTGCTGGAACCGAATACACAGACCTGTAAATACAACTATCTACCCAAGAACGGCATGTACGAAGTCCCGG
AGCTTCCTGGTATCGGCCAGGAGCTGACCGAGGAAACCATGAAAAAATCACCAACCATCACCGTAAAATAA

Upstream 100 bases:

>100_bases
TATACCGGCGGCTTACTATGCCTGGTTTTTATCAGCGCTATCGCCGTGGTATCGGCATTAATCTTAACGATTAAAAAATA
TTAATTACGAGGAGTAAATG

Downstream 100 bases:

>100_bases
GCCAACTGTCTGCCTGCGCCGCAGGCAGACCCCCTGTATTTGCGAGTCGTATCAACACGACCTTATCCAGCCTGAGATAA
AATCCTCTCTGTAAAGGGGT

Product: mandelate racemase/muconate lactonizing enzyme family protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKITSVDIIDVANDFASATSKWRPVVVKINTDEGISGFGEVGLAYGVGASAGIGMAKDLAAIIIGMDPMNNEAIWEKMLK
KTFWGQGGGGIFSAAMSGIDIALWDIKGKAWGVPLYKMLGGKSREKIRTYASQLQFDWGDGSDKDMLTEPEQYAQAALTA
VSEGYDAIKVDTVAMDRHGNWNQQNLNGPLTDKILRLGYDRMAAIRDAVGPDVDIIAEMHAFTDTTSAIQFGRMIEELGI
FYYEEPVMPLNPGQMKQVADKVNIPLAAGERIYWRWGYRPFLENGSLSVIQPDICTCGGITEVKKICDMAHVYDKTVQIH
VCGGPISTAVALHMETAIPNFVIHELHRYALLEPNTQTCKYNYLPKNGMYEVPELPGIGQELTEETMKKSPTITVK

Sequences:

>Translated_396_residues
MKITSVDIIDVANDFASATSKWRPVVVKINTDEGISGFGEVGLAYGVGASAGIGMAKDLAAIIIGMDPMNNEAIWEKMLK
KTFWGQGGGGIFSAAMSGIDIALWDIKGKAWGVPLYKMLGGKSREKIRTYASQLQFDWGDGSDKDMLTEPEQYAQAALTA
VSEGYDAIKVDTVAMDRHGNWNQQNLNGPLTDKILRLGYDRMAAIRDAVGPDVDIIAEMHAFTDTTSAIQFGRMIEELGI
FYYEEPVMPLNPGQMKQVADKVNIPLAAGERIYWRWGYRPFLENGSLSVIQPDICTCGGITEVKKICDMAHVYDKTVQIH
VCGGPISTAVALHMETAIPNFVIHELHRYALLEPNTQTCKYNYLPKNGMYEVPELPGIGQELTEETMKKSPTITVK
>Mature_396_residues
MKITSVDIIDVANDFASATSKWRPVVVKINTDEGISGFGEVGLAYGVGASAGIGMAKDLAAIIIGMDPMNNEAIWEKMLK
KTFWGQGGGGIFSAAMSGIDIALWDIKGKAWGVPLYKMLGGKSREKIRTYASQLQFDWGDGSDKDMLTEPEQYAQAALTA
VSEGYDAIKVDTVAMDRHGNWNQQNLNGPLTDKILRLGYDRMAAIRDAVGPDVDIIAEMHAFTDTTSAIQFGRMIEELGI
FYYEEPVMPLNPGQMKQVADKVNIPLAAGERIYWRWGYRPFLENGSLSVIQPDICTCGGITEVKKICDMAHVYDKTVQIH
VCGGPISTAVALHMETAIPNFVIHELHRYALLEPNTQTCKYNYLPKNGMYEVPELPGIGQELTEETMKKSPTITVK

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=326, Percent_Identity=31.5950920245399, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787864, Length=375, Percent_Identity=27.7333333333333, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI226510960, Length=381, Percent_Identity=23.0971128608924, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 43556; Mature: 43556

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITSVDIIDVANDFASATSKWRPVVVKINTDEGISGFGEVGLAYGVGASAGIGMAKDLA
CCCEEEEHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHE
AIIIGMDPMNNEAIWEKMLKKTFWGQGGGGIFSAAMSGIDIALWDIKGKAWGVPLYKMLG
EEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHC
GKSREKIRTYASQLQFDWGDGSDKDMLTEPEQYAQAALTAVSEGYDAIKVDTVAMDRHGN
CCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCC
WNQQNLNGPLTDKILRLGYDRMAAIRDAVGPDVDIIAEMHAFTDTTSAIQFGRMIEELGI
CCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCC
FYYEEPVMPLNPGQMKQVADKVNIPLAAGERIYWRWGYRPFLENGSLSVIQPDICTCGGI
EEEECCCCCCCCCHHHHHHHHHCCCEECCCEEEEEECCCHHHCCCCEEEECCCCCCCCCH
TEVKKICDMAHVYDKTVQIHVCGGPISTAVALHMETAIPNFVIHELHRYALLEPNTQTCK
HHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCCEE
YNYLPKNGMYEVPELPGIGQELTEETMKKSPTITVK
EECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEC
>Mature Secondary Structure
MKITSVDIIDVANDFASATSKWRPVVVKINTDEGISGFGEVGLAYGVGASAGIGMAKDLA
CCCEEEEHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHE
AIIIGMDPMNNEAIWEKMLKKTFWGQGGGGIFSAAMSGIDIALWDIKGKAWGVPLYKMLG
EEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHC
GKSREKIRTYASQLQFDWGDGSDKDMLTEPEQYAQAALTAVSEGYDAIKVDTVAMDRHGN
CCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCC
WNQQNLNGPLTDKILRLGYDRMAAIRDAVGPDVDIIAEMHAFTDTTSAIQFGRMIEELGI
CCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCC
FYYEEPVMPLNPGQMKQVADKVNIPLAAGERIYWRWGYRPFLENGSLSVIQPDICTCGGI
EEEECCCCCCCCCHHHHHHHHHCCCEECCCEEEEEECCCHHHCCCCEEEECCCCCCCCCH
TEVKKICDMAHVYDKTVQIHVCGGPISTAVALHMETAIPNFVIHELHRYALLEPNTQTCK
HHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCCEE
YNYLPKNGMYEVPELPGIGQELTEETMKKSPTITVK
EECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA