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The map label for this gene is gudP [H]

Identifier: 194736132

GI number: 194736132

Start: 3915684

End: 3916946

Strand: Direct

Name: gudP [H]

Synonym: SeSA_A4044

Alternate gene names: 194736132

Gene position: 3915684-3916946 (Clockwise)

Preceding gene: 194736770

Following gene: 194736491

Centisome position: 83.15

GC content: 47.35

Gene sequence:

>1263_bases
ATGTCGATGGCCCTTACCGCCCCCCCAACCAGGAAAAGATTTTTAATCGTTGCCTGTCTGTTTATTGGAATATTTATTGC
TTATCTCGATCGCGTTAATGTTTCGGTATTAGCCGCGAATGAACCCTTCTTAGCCTATATGGGTATTGAAAGTATGCCAT
TGCAAATCGGCATGATGATGACCGTCTTTCTGGCCGCTTATGGTATCGCTAACGTTGTATTATCACCGCTTGGCGATTAT
CTCGGCCCCAGAAAAGCAATGATGCTTTGTATTCTGATCTGGACTATCGCTTTAATGGTTGGCGGCGTAGCAACATCATT
CGCTCTAATTATTATTTGCCGTATATTACTGGGCATCGGAGAGGGATTTTATTATCCACTGCAAAGCGTATTTATTAAAA
ACTGGTTCCCGAAGCAGGAGCGCGGCAGAGCAAACGCGGCGTGGATCGTCGGCCAGTCGGTGGCACCCGCCATTGCGATG
CCTTTTTTCACCTGGTGGATAGGCACCCACGGCTGGCGTTCCAACTTCTTTTTATGCGCCGCTCTCGGGTTAATCCCACT
CTGGCTACTCTGGCGATATGTTGCTGATAAACCAGAACAACATAAAAGTATCAGCGAACAGGAACTGGCTTATATCAAAG
CCGGACAGGAAACGGAAAGCGCAGGCAACAGCGAAAGTTTTATGTTGCGGGTCAAACCGGTGATCACCAACTATTGCTAC
TGGTTGCTGGTGCTGTGGTACCTGTGCCTGCAATGCCTGTACTGGGGGATGATTACCTGGCTGCCGACCTATCTTAAATC
AGCCAGAGGATTTAGCTGGGCGGAAATGGGCTGGCTGGCGTCGCTTCCCTTTGTCCTGTCAATATTTTCTAAAGCCGCTG
CGGGGATCTTCGTCGATAAAATAGGACGCAGCGCCCCCATATTAATGGTATTAATGTTTTTCGCTGGCGTCAGTATCTAT
TTCGGTACCATAACCGAACATAAATATATGTCAGCGGTACTCCTCTCCTTTGCTGTTGCTTTCTGTACGATGGGTACGCC
CGTTGCCTGGACGTTATTACAGGGAATGATACCCGGAAAATCTATTTCCGCCGCCAGCGGCGTAATGAACGGCGTCGCCA
ATGGACTCTCTTCATTATCTCCCGTATTTATCGGCTTATTTATTTCTATCACTGGAACTTATACCGGCGGCTTACTATGC
CTGGTTTTTATCAGCGCTATCGCCGTGGTATCGGCATTAATCTTAACGATTAAAAAATATTAA

Upstream 100 bases:

>100_bases
CATCATCACTTAGAGCCTAATGGGATTGGCTCTTAATCAGTAAAAATCAACAAAAACTTATATTTTAAAACAACCTTATC
CGATGAGAAGGAGATCGCTA

Downstream 100 bases:

>100_bases
TTACGAGGAGTAAATGATGAAAATTACCAGCGTTGATATTATTGATGTGGCGAACGATTTTGCGTCCGCCACCAGCAAAT
GGCGTCCGGTGGTGGTAAAA

Product: putative permease

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIESMPLQIGMMMTVFLAAYGIANVVLSPLGDY
LGPRKAMMLCILIWTIALMVGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAM
PFFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGNSESFMLRVKPVITNYCY
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGIFVDKIGRSAPILMVLMFFAGVSIY
FGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLC
LVFISAIAVVSALILTIKKY

Sequences:

>Translated_420_residues
MSMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIESMPLQIGMMMTVFLAAYGIANVVLSPLGDY
LGPRKAMMLCILIWTIALMVGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAM
PFFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGNSESFMLRVKPVITNYCY
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGIFVDKIGRSAPILMVLMFFAGVSIY
FGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLC
LVFISAIAVVSALILTIKKY
>Mature_419_residues
SMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIESMPLQIGMMMTVFLAAYGIANVVLSPLGDYL
GPRKAMMLCILIWTIALMVGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMP
FFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGNSESFMLRVKPVITNYCYW
LLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGIFVDKIGRSAPILMVLMFFAGVSIYF
GTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCL
VFISAIAVVSALILTIKKY

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=262, Percent_Identity=24.4274809160305, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI6912666, Length=320, Percent_Identity=23.75, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI9945322, Length=184, Percent_Identity=25.5434782608696, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=26.7441860465116, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI2367379, Length=407, Percent_Identity=27.027027027027, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082320, Length=429, Percent_Identity=27.039627039627, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789515, Length=413, Percent_Identity=23.0024213075061, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082071, Length=428, Percent_Identity=23.1308411214953, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367193, Length=276, Percent_Identity=24.2753623188406, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082404, Length=163, Percent_Identity=26.9938650306748, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790550, Length=260, Percent_Identity=25.3846153846154, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17569727, Length=305, Percent_Identity=27.2131147540984, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI86561091, Length=241, Percent_Identity=26.9709543568465, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25141318, Length=241, Percent_Identity=26.9709543568465, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25141316, Length=241, Percent_Identity=26.9709543568465, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25141341, Length=273, Percent_Identity=24.5421245421245, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32567120, Length=203, Percent_Identity=26.1083743842365, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561502, Length=203, Percent_Identity=26.1083743842365, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561498, Length=210, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115534558, Length=210, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=200, Percent_Identity=27, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115533554, Length=200, Percent_Identity=27, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17566884, Length=388, Percent_Identity=25.7731958762887, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560966, Length=233, Percent_Identity=26.6094420600858, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=346, Percent_Identity=22.5433526011561, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=236, Percent_Identity=23.3050847457627, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=274, Percent_Identity=21.5328467153285, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71991448, Length=258, Percent_Identity=24.8062015503876, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991453, Length=258, Percent_Identity=24.8062015503876, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193208223, Length=209, Percent_Identity=26.7942583732057, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17554962, Length=239, Percent_Identity=23.0125523012552, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534562, Length=232, Percent_Identity=25.4310344827586, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561500, Length=231, Percent_Identity=25.5411255411255, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=203, Percent_Identity=23.6453201970443, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32565916, Length=203, Percent_Identity=23.6453201970443, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641682, Length=269, Percent_Identity=25.6505576208178, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550460, Length=429, Percent_Identity=22.6107226107226, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24654215, Length=322, Percent_Identity=23.6024844720497, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19922400, Length=307, Percent_Identity=23.7785016286645, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI20130167, Length=416, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580790, Length=271, Percent_Identity=23.6162361623616, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24583789, Length=247, Percent_Identity=24.2914979757085, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648416, Length=308, Percent_Identity=22.7272727272727, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356189, Length=308, Percent_Identity=22.7272727272727, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655271, Length=409, Percent_Identity=21.760391198044, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130135, Length=409, Percent_Identity=21.760391198044, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24655255, Length=321, Percent_Identity=22.1183800623053, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28573299, Length=402, Percent_Identity=23.134328358209, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46227; Mature: 46096

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIESMPLQIGMMM
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCHHHHHHH
TVFLAAYGIANVVLSPLGDYLGPRKAMMLCILIWTIALMVGGVATSFALIIICRILLGIG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMPFFTWWIGTHGWRSNFFLCA
CCHHHHHHHHHHHHCCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
ALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGNSESFMLRVKPVITNYCY
HHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHH
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGIFVDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRSAPILMVLMFFAGVSIYFGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
SISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCLVFISAIAVVSALILTIKKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIESMPLQIGMMM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCHHHHHHH
TVFLAAYGIANVVLSPLGDYLGPRKAMMLCILIWTIALMVGGVATSFALIIICRILLGIG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMPFFTWWIGTHGWRSNFFLCA
CCHHHHHHHHHHHHCCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
ALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGNSESFMLRVKPVITNYCY
HHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHH
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGIFVDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRSAPILMVLMFFAGVSIYFGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
SISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCLVFISAIAVVSALILTIKKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]