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The map label for this gene is idnR [H]

Identifier: 194736291

GI number: 194736291

Start: 4600783

End: 4601781

Strand: Reverse

Name: idnR [H]

Synonym: SeSA_A4736

Alternate gene names: 194736291

Gene position: 4601781-4600783 (Counterclockwise)

Preceding gene: 194734465

Following gene: 194737065

Centisome position: 97.72

GC content: 50.15

Gene sequence:

>999_bases
ATGAGGAATCACAGAATTTCTTTGCAGGATATCGCTACGCTTGCTGGCGTGACAAAAATGACGGTGAGCCGTTACATCCG
CTCGCCGAAAAAAGTCGCCAGGGAAACCGGCGAGCGTATTGCGCAGATCATGGAGGAAATTAACTACATACCAAATCGCG
CGCCTGCTATGCTGTTAAACGCGCAAAGTTACACTCTGGGCGTGCTGATCCCCTCTTTTCAGAATCAGTTGTTTGCCGAC
ATTCTTGCCGGGATTGAATCCGTAACGTCGGGTCATAACTACCAAACTCTCATTGCGAATTACAATTACAATCGCGATTC
GGAAGAAGAGTCCGTTATCAATTTACTGTCTTACAATATCGACGGCATTATTCTTTCAGAAAAATATCATACCCTCAGAA
CCGTCAAATTCCTGCGCTCAGCAACCCTTCCGATTGTAGAACTCATGGACATCCAGGGCGATCGCTTAGATATGGAGGTG
GGGTTTGATAACCGTCAGGCCGCCTTTGATATGGTCAGTACCATGCTGGATAAACGCCAGCGGCGAAAAATCCTCTATCT
GGGTTCAAAAGACGATATCCGAGATGAGCAGCGTTATCACGGCTACTGCGATGCGATGACGCGCCGGGGGCTGGCGCCGT
TGCGCATCAATCCCCGCGCTATCTCCTCTATCCATCTGGGGATACAGCTAATGCGTGATGCGCTTACTGCGCACCCGGAC
GTGGATGGCGTCTTTTGTACAAATGACGATATCGCAATGGGCGCTCTACTGTGGTGCCGCGAGCGTCAACTGGCCGTACC
GGAGCAGATCTCCATCGCCGGCTTCCACGGTCTGGAGATGGGCAGGCAAATGATACCGAGCCTCGCCAGCGTAATTACCC
CTCGTTTTGAGATCGGGCGCAGAGCCGCGCAGATGTTGCTCAACAAAATTAAAAATAACGATCTCAACCATAATACGATT
GATTTGGGTTATCAGATTTATCACGGCAGCACGTTATAA

Upstream 100 bases:

>100_bases
GCTGGGCGTACTGGCGCTGAATGCGGTTCTGCATTAATTCATCATCCGCAGCCCAATTAACCATGGGGGCGACGTTCCCG
CCCCCGGTACTGGAGAAAAC

Downstream 100 bases:

>100_bases
ATTTTTTGATCTACTTTTTCCCGCAGCTTGCCTGAGCTTAACGCGTAGCCAAAAGCGCCACGCGTCAGGTTACGCACTAC
ATCATTCGAGGAATACCAGG

Product: HTH-type transcriptional regulator IdnR

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVARETGERIAQIMEEINYIPNRAPAMLLNAQSYTLGVLIPSFQNQLFAD
ILAGIESVTSGHNYQTLIANYNYNRDSEEESVINLLSYNIDGIILSEKYHTLRTVKFLRSATLPIVELMDIQGDRLDMEV
GFDNRQAAFDMVSTMLDKRQRRKILYLGSKDDIRDEQRYHGYCDAMTRRGLAPLRINPRAISSIHLGIQLMRDALTAHPD
VDGVFCTNDDIAMGALLWCRERQLAVPEQISIAGFHGLEMGRQMIPSLASVITPRFEIGRRAAQMLLNKIKNNDLNHNTI
DLGYQIYHGSTL

Sequences:

>Translated_332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVARETGERIAQIMEEINYIPNRAPAMLLNAQSYTLGVLIPSFQNQLFAD
ILAGIESVTSGHNYQTLIANYNYNRDSEEESVINLLSYNIDGIILSEKYHTLRTVKFLRSATLPIVELMDIQGDRLDMEV
GFDNRQAAFDMVSTMLDKRQRRKILYLGSKDDIRDEQRYHGYCDAMTRRGLAPLRINPRAISSIHLGIQLMRDALTAHPD
VDGVFCTNDDIAMGALLWCRERQLAVPEQISIAGFHGLEMGRQMIPSLASVITPRFEIGRRAAQMLLNKIKNNDLNHNTI
DLGYQIYHGSTL
>Mature_332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVARETGERIAQIMEEINYIPNRAPAMLLNAQSYTLGVLIPSFQNQLFAD
ILAGIESVTSGHNYQTLIANYNYNRDSEEESVINLLSYNIDGIILSEKYHTLRTVKFLRSATLPIVELMDIQGDRLDMEV
GFDNRQAAFDMVSTMLDKRQRRKILYLGSKDDIRDEQRYHGYCDAMTRRGLAPLRINPRAISSIHLGIQLMRDALTAHPD
VDGVFCTNDDIAMGALLWCRERQLAVPEQISIAGFHGLEMGRQMIPSLASVITPRFEIGRRAAQMLLNKIKNNDLNHNTI
DLGYQIYHGSTL

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=89.1566265060241, Blast_Score=620, Evalue=1e-179,
Organism=Escherichia coli, GI48994940, Length=332, Percent_Identity=45.7831325301205, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1790369, Length=319, Percent_Identity=26.9592476489028, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789068, Length=302, Percent_Identity=25.8278145695364, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790194, Length=320, Percent_Identity=25.9375, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789202, Length=305, Percent_Identity=25.5737704918033, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788474, Length=319, Percent_Identity=25.0783699059561, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787948, Length=321, Percent_Identity=23.6760124610592, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787906, Length=261, Percent_Identity=23.7547892720307, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786540, Length=290, Percent_Identity=22.7586206896552, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786268, Length=294, Percent_Identity=27.5510204081633, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787580, Length=326, Percent_Identity=20.2453987730061, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37656; Mature: 37656

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVARETGERIAQIMEEINYIPNRAPAMLLN
CCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
AQSYTLGVLIPSFQNQLFADILAGIESVTSGHNYQTLIANYNYNRDSEEESVINLLSYNI
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCC
DGIILSEKYHTLRTVKFLRSATLPIVELMDIQGDRLDMEVGFDNRQAAFDMVSTMLDKRQ
CEEEECCHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
RRKILYLGSKDDIRDEQRYHGYCDAMTRRGLAPLRINPRAISSIHLGIQLMRDALTAHPD
CCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCC
VDGVFCTNDDIAMGALLWCRERQLAVPEQISIAGFHGLEMGRQMIPSLASVITPRFEIGR
CCEEEECCCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHH
RAAQMLLNKIKNNDLNHNTIDLGYQIYHGSTL
HHHHHHHHHHHCCCCCCCEEEEEEEEECCCCC
>Mature Secondary Structure
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVARETGERIAQIMEEINYIPNRAPAMLLN
CCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
AQSYTLGVLIPSFQNQLFADILAGIESVTSGHNYQTLIANYNYNRDSEEESVINLLSYNI
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCC
DGIILSEKYHTLRTVKFLRSATLPIVELMDIQGDRLDMEVGFDNRQAAFDMVSTMLDKRQ
CEEEECCHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
RRKILYLGSKDDIRDEQRYHGYCDAMTRRGLAPLRINPRAISSIHLGIQLMRDALTAHPD
CCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCC
VDGVFCTNDDIAMGALLWCRERQLAVPEQISIAGFHGLEMGRQMIPSLASVITPRFEIGR
CCEEEECCCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHH
RAAQMLLNKIKNNDLNHNTIDLGYQIYHGSTL
HHHHHHHHHHHCCCCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]