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The map label for this gene is mcrB [H]

Identifier: 194334822

GI number: 194334822

Start: 2222348

End: 2222635

Strand: Reverse

Name: mcrB [H]

Synonym: Paes_2025

Alternate gene names: 194334822

Gene position: 2222635-2222348 (Counterclockwise)

Preceding gene: 194334823

Following gene: 194334821

Centisome position: 88.45

GC content: 56.94

Gene sequence:

>288_bases
ATGAACCCTGAAAAAGTCGACAGAGCCAGACTGCACAAGCTTACCGACCTGCCCAATATCGGTCCGGCTCTTGCGGATGA
TCTTCGTCTGATCGGTATCGAAAGACCGTTGGATCTGGTGGGTCGCTCGCCCGTCGAACTCTATCAGGCCTTGTCATCGA
TCACAGGCACGCGACAGGACCCCTGCGTGCTGGACGTGTTCATCTCCATCACCCGCTTCATGGAGGGGGAGGAGCCTCGC
CCGTGGTGGCACTACAGCACCGAACGGAAAAAGATGTCTCACACATGA

Upstream 100 bases:

>100_bases
AAGCCTCTCTTTCCGGTGAGTGAACCGGAGCGGGGCTCTTTGTGGCCGCATTGTCAGCACAGGCGGGAGGAATCGTCAAC
AGGAAAAAGTCTTTTCTGAT

Downstream 100 bases:

>100_bases
AGATGTTCTGGAGTTACGCACGGCTCGACGACATGGAGCCGAAACGCAAGGTATCGAAACTGCGCAAGGCGTTCGAAAAT
GTCCTGTCGCAGACGCAGGG

Product: putative mitomycin resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MNPEKVDRARLHKLTDLPNIGPALADDLRLIGIERPLDLVGRSPVELYQALSSITGTRQDPCVLDVFISITRFMEGEEPR
PWWHYSTERKKMSHT

Sequences:

>Translated_95_residues
MNPEKVDRARLHKLTDLPNIGPALADDLRLIGIERPLDLVGRSPVELYQALSSITGTRQDPCVLDVFISITRFMEGEEPR
PWWHYSTERKKMSHT
>Mature_95_residues
MNPEKVDRARLHKLTDLPNIGPALADDLRLIGIERPLDLVGRSPVELYQALSSITGTRQDPCVLDVFISITRFMEGEEPR
PWWHYSTERKKMSHT

Specific function: Involved in mitomycin resistance. May operate with mcrA or may be a type of transcriptional activator protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021725 [H]

Pfam domain/function: PF11731 Cdd1 [H]

EC number: NA

Molecular weight: Translated: 10927; Mature: 10927

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPEKVDRARLHKLTDLPNIGPALADDLRLIGIERPLDLVGRSPVELYQALSSITGTRQD
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCCCC
PCVLDVFISITRFMEGEEPRPWWHYSTERKKMSHT
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MNPEKVDRARLHKLTDLPNIGPALADDLRLIGIERPLDLVGRSPVELYQALSSITGTRQD
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCCCC
PCVLDVFISITRFMEGEEPRPWWHYSTERKKMSHT
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7517396 [H]