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The map label for this gene is hypA

Identifier: 194334450

GI number: 194334450

Start: 1790910

End: 1791251

Strand: Reverse

Name: hypA

Synonym: Paes_1645

Alternate gene names: 194334450

Gene position: 1791251-1790910 (Counterclockwise)

Preceding gene: 194334453

Following gene: 194334449

Centisome position: 71.28

GC content: 49.42

Gene sequence:

>342_bases
ATGCACGAAATGTCTATCGCTCTTTCCGTCGTTGATGCTATAACGGCAAGGGCAAGGGAGGAACAGGCTGAAAAAGTGAC
CGCTATCGAGCTGGTGGCAGGAAAGCTTTCAGGGGTAGAGATTGAGTCTCTGAAGTTCTGTTTCTCTGCAGCTGTTCGCG
GTACAATCATGGAGGATGCTGAGCTTATGGTGACGGTTCCTCTTTCGGAAGGTCTTTGTGAGGTGTGCGGGGAACGGTTT
GCTGTCGACGGCTATTATACGCAATGTCCTTCCTGTGGTTCTTACAAGGTGAGGATTGTTTCAGGAAAAGAGTTGTCAAT
ACGCTCGATAACGCTGGAGTAG

Upstream 100 bases:

>100_bases
GCTCTCTGGGGGCAGTTGCGGGAAGCGGAAGGATTGGGTAGGTTACAGAGGAGATTATTTTTTCCCAGCCATCGCAGAAC
TCGTTAATCCTTGGATGTGT

Downstream 100 bases:

>100_bases
CGCGATCGCCGTTGTATGCTGCAGGTGCAACCAGAGCGGCTTGAGGTGATCTGCAAAACCCATTTACGGTTGATTTCTGA
TTTGATTTTCGTTCATCCAA

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHEMSIALSVVDAITARAREEQAEKVTAIELVAGKLSGVEIESLKFCFSAAVRGTIMEDAELMVTVPLSEGLCEVCGERF
AVDGYYTQCPSCGSYKVRIVSGKELSIRSITLE

Sequences:

>Translated_113_residues
MHEMSIALSVVDAITARAREEQAEKVTAIELVAGKLSGVEIESLKFCFSAAVRGTIMEDAELMVTVPLSEGLCEVCGERF
AVDGYYTQCPSCGSYKVRIVSGKELSIRSITLE
>Mature_113_residues
MHEMSIALSVVDAITARAREEQAEKVTAIELVAGKLSGVEIESLKFCFSAAVRGTIMEDAELMVTVPLSEGLCEVCGERF
AVDGYYTQCPSCGSYKVRIVSGKELSIRSITLE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=30.0884955752212, Blast_Score=69, Evalue=5e-14,
Organism=Escherichia coli, GI1789081, Length=114, Percent_Identity=30.7017543859649, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_PROA2 (B4S9J3)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016310.1
- GeneID:   6459318
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_1645
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- ProtClustDB:   CLSK571892
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12224; Mature: 12224

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMSIALSVVDAITARAREEQAEKVTAIELVAGKLSGVEIESLKFCFSAAVRGTIMEDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEECCC
ELMVTVPLSEGLCEVCGERFAVDGYYTQCPSCGSYKVRIVSGKELSIRSITLE
EEEEEEECCCCHHHHCCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEC
>Mature Secondary Structure
MHEMSIALSVVDAITARAREEQAEKVTAIELVAGKLSGVEIESLKFCFSAAVRGTIMEDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEECCC
ELMVTVPLSEGLCEVCGERFAVDGYYTQCPSCGSYKVRIVSGKELSIRSITLE
EEEEEEECCCCHHHHCCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA