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The map label for this gene is hypB [H]

Identifier: 194334449

GI number: 194334449

Start: 1789913

End: 1790725

Strand: Reverse

Name: hypB [H]

Synonym: Paes_1644

Alternate gene names: 194334449

Gene position: 1790725-1789913 (Counterclockwise)

Preceding gene: 194334450

Following gene: 194334448

Centisome position: 71.26

GC content: 51.05

Gene sequence:

>813_bases
ATGTGCGATACCTGTGGATGTTCTTCTGAAGGGGGGGCGGTCTTGTGTAAGCCGGGAGATGCTTCGTGGCATGTTCATCT
TCACGGCCATGATGATTCCGGCCACGGCCACGGAGGCCATCACCATCATGCCGATGAGTCTCATGCGCATCATGCCGGTG
GCCGAAAGGTCGCGATGGAGCAGGATGTGCTTCTTCACAATAACCTCCTTGCCGAACGCAACCGGGGGTATTTTGATGCA
AGAAATATTTTTGCGTTGAATTTTCTCAGCTCACCCGGATCAGGCAAAACGACACTGCTTGAAAAGACCATACCGATGAT
CGGCAGCGATTTTCCTGTCAGCGTTATCGAAGGGGATCAGCAGACCATGCGTGATGCAGAACGTATCGATGCTCTCGGTG
TTCCGGTCCTTCAGGTCAATACCGGTACAGGATGCCATCTTGATGCTCAGATGATTCAGAGGGCGGTCAAGGAGATGGAT
ATTGCGGATCGCTCTCTGCTGTGCATTGAAAATGTTGGAAACCTGGTCTGCCCCGCGCTGTTTGATCTTGGTGAAGCCTT
GAAGGTGGTCGTTATCAGTGTTACGGAAGGGGATGATAAACCGCTGAAATATCCGACGATGTTTCATGAGGCCGATGTCT
GTATTCTCAACAAGATTGACCTTCTGCCGTATGTTCCCTTTGATGCTGTGCAATGCCGGGAAAATGCGATGAACGTCAAT
CATCATCTTGCCTGGTTTGAGCTTTCAGCTTCAACAGGTGAAGGAGTTGACGCATGGGTGGCGTGGTTGAAAGCAGCAAT
GAACCGATCCTGA

Upstream 100 bases:

>100_bases
ATTTTCGTTCATCCAAAACCATAACTTCTTTACGAATAACGAATAACGAATAACGAATAACGAATAACGAATAACGAATA
ACGAATAACGAATAACGAAT

Downstream 100 bases:

>100_bases
GCGGGAGAGCAAGGCGCCTGCGTCTCGCGGTTAACGGGATTGTTCAGGGTGTCGGGTTCCGGCCTTATGTCTACCGCCTT
GCGACATCTCTGGGGCTGAG

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MCDTCGCSSEGGAVLCKPGDASWHVHLHGHDDSGHGHGGHHHHADESHAHHAGGRKVAMEQDVLLHNNLLAERNRGYFDA
RNIFALNFLSSPGSGKTTLLEKTIPMIGSDFPVSVIEGDQQTMRDAERIDALGVPVLQVNTGTGCHLDAQMIQRAVKEMD
IADRSLLCIENVGNLVCPALFDLGEALKVVVISVTEGDDKPLKYPTMFHEADVCILNKIDLLPYVPFDAVQCRENAMNVN
HHLAWFELSASTGEGVDAWVAWLKAAMNRS

Sequences:

>Translated_270_residues
MCDTCGCSSEGGAVLCKPGDASWHVHLHGHDDSGHGHGGHHHHADESHAHHAGGRKVAMEQDVLLHNNLLAERNRGYFDA
RNIFALNFLSSPGSGKTTLLEKTIPMIGSDFPVSVIEGDQQTMRDAERIDALGVPVLQVNTGTGCHLDAQMIQRAVKEMD
IADRSLLCIENVGNLVCPALFDLGEALKVVVISVTEGDDKPLKYPTMFHEADVCILNKIDLLPYVPFDAVQCRENAMNVN
HHLAWFELSASTGEGVDAWVAWLKAAMNRS
>Mature_270_residues
MCDTCGCSSEGGAVLCKPGDASWHVHLHGHDDSGHGHGGHHHHADESHAHHAGGRKVAMEQDVLLHNNLLAERNRGYFDA
RNIFALNFLSSPGSGKTTLLEKTIPMIGSDFPVSVIEGDQQTMRDAERIDALGVPVLQVNTGTGCHLDAQMIQRAVKEMD
IADRSLLCIENVGNLVCPALFDLGEALKVVVISVTEGDDKPLKYPTMFHEADVCILNKIDLLPYVPFDAVQCRENAMNVN
HHLAWFELSASTGEGVDAWVAWLKAAMNRS

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=285, Percent_Identity=47.3684210526316, Blast_Score=243, Evalue=7e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 29388; Mature: 29388

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00816 AIPM_HOMOCIT_SYNTH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDTCGCSSEGGAVLCKPGDASWHVHLHGHDDSGHGHGGHHHHADESHAHHAGGRKVAME
CCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCEEEEC
QDVLLHNNLLAERNRGYFDARNIFALNFLSSPGSGKTTLLEKTIPMIGSDFPVSVIEGDQ
CCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEHHHHHHHCCCCCCEEEEECCH
QTMRDAERIDALGVPVLQVNTGTGCHLDAQMIQRAVKEMDIADRSLLCIENVGNLVCPAL
HHHHHHHHHHHCCCCEEEEECCCCCEECHHHHHHHHHHCCCCCCCEEEHHHCCHHHHHHH
FDLGEALKVVVISVTEGDDKPLKYPTMFHEADVCILNKIDLLPYVPFDAVQCRENAMNVN
HHHHCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
HHLAWFELSASTGEGVDAWVAWLKAAMNRS
CEEEEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCDTCGCSSEGGAVLCKPGDASWHVHLHGHDDSGHGHGGHHHHADESHAHHAGGRKVAME
CCCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCEEEEC
QDVLLHNNLLAERNRGYFDARNIFALNFLSSPGSGKTTLLEKTIPMIGSDFPVSVIEGDQ
CCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEHHHHHHHCCCCCCEEEEECCH
QTMRDAERIDALGVPVLQVNTGTGCHLDAQMIQRAVKEMDIADRSLLCIENVGNLVCPAL
HHHHHHHHHHHCCCCEEEEECCCCCEECHHHHHHHHHHCCCCCCCEEEHHHCCHHHHHHH
FDLGEALKVVVISVTEGDDKPLKYPTMFHEADVCILNKIDLLPYVPFDAVQCRENAMNVN
HHHHCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
HHLAWFELSASTGEGVDAWVAWLKAAMNRS
CEEEEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]