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The map label for this gene is ackA [H]

Identifier: 194334426

GI number: 194334426

Start: 1764579

End: 1765760

Strand: Reverse

Name: ackA [H]

Synonym: Paes_1621

Alternate gene names: 194334426

Gene position: 1765760-1764579 (Counterclockwise)

Preceding gene: 194334431

Following gene: 194334425

Centisome position: 70.27

GC content: 52.12

Gene sequence:

>1182_bases
ATGAGTATTGTTATGGCTGTCAATACAGGATCGTCAAGTATCCGGTTTGCGTTGTATCGAATGGATCAGGGCGAGATTCC
GCTTTATACCGGTGCTCTGACCTCGATAGCTTCGAAAGACGCGATGTTTTCAGTTATCGATTCCGATGGTCATGCGTTAA
TCCGAGAAGCGGTATGTGTTGCTGACCATGGAGCTGCCTGCGAGCATGTATTCGGATGGCTGCATGACAGCAATACCCTC
CGTCCTGATGCAGTGGGGCACCGGATCGTTCATGGAGGTCCATTGTACTCTTCTCCTCAGGTTGTTTCACCTGCACTGGT
CGAATCACTCCACGGACTTGTCGTTTTTGCACCGCAACACCTTCCGCAGGCATTGCAGGCTCTTGACCACGCGTCCCGGC
TTTTTCCCGGCAGCACTCAGGTTGCATGTTTTGATACGGCATTTCACCGTTCCATGCCGGATGTTGCCCGTCTCTATGCG
CTGCCGGAAGAGGTTCGTCGTCATGGCGTTCAGCGTTATGGTTTTCATGGGCTTTCGTATCAGTATCTGATGAGTGAACT
TGAGCGTACAGTCGGTACAGAGATTGCACGGGGAAGGCTTGTTCTTGCACATCTTGGACATGGAGCGAGTATGGCTGCCG
TCAAAGAGGGCAGAAGTATCGATACGACAATGGGGTTTTCCCCGGCGGGCGGGCTGGTCATGAGTACCAGAAGCGGCGAT
CTCGACCCCGGAGTGCTTCTCTTTCTTCTCGAGCAGGAACATATGGATGCCGCTGCCATTACAACGATGATCAACAGTGG
ATCAGGAATGCTTGGATTGTCGGGGATCAGTGGCGATATGCAGATGCTTCTTGATGCTGTCGGGGATAGTCACCGGGCCC
GTCAGGCGGTAGATCTATTCTGTTATCAGGCAAAAAAGACTATTGGAGCTTTTGCTGCTGCCATGGGCGGACTTGATTCA
GTGATTTTTACCGGTGGGATTGGTGAGCATTCAGCCGTGATTCGACAGCGTCTCTGCAGTGGGTTGGGTTTTCTCGGTAT
AGAGCTTGATGATGGGAGAAATCATCATCATGAGCCGGTCATTTCCGGAGAGGCAAGTCGCGTGGATATCAGAGTTATGG
CGACAAATGAGGAGCTGATGATTGCCCGGCTTGTTGCCGCAGAGCTGTCAGCTCATGAATGA

Upstream 100 bases:

>100_bases
AGTAATGCTGAAAACTAAATCGCAGGTTTCATTAGATTGATCAAGAAGGCAGGTGCTGCCAGATTCCTTTGTCAGCAATG
AAGATGATGAGGAGCTGCAT

Downstream 100 bases:

>100_bases
ACAGGCGAGACTGATGGGTGAGTGTCGTGTTCGGGATTATGGTGTTTGGTAGTCATTTTTTTCAGTACAATTGAAAACGG
AGTCGATTCATGAGCGATGC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSIVMAVNTGSSSIRFALYRMDQGEIPLYTGALTSIASKDAMFSVIDSDGHALIREAVCVADHGAACEHVFGWLHDSNTL
RPDAVGHRIVHGGPLYSSPQVVSPALVESLHGLVVFAPQHLPQALQALDHASRLFPGSTQVACFDTAFHRSMPDVARLYA
LPEEVRRHGVQRYGFHGLSYQYLMSELERTVGTEIARGRLVLAHLGHGASMAAVKEGRSIDTTMGFSPAGGLVMSTRSGD
LDPGVLLFLLEQEHMDAAAITTMINSGSGMLGLSGISGDMQMLLDAVGDSHRARQAVDLFCYQAKKTIGAFAAAMGGLDS
VIFTGGIGEHSAVIRQRLCSGLGFLGIELDDGRNHHHEPVISGEASRVDIRVMATNEELMIARLVAAELSAHE

Sequences:

>Translated_393_residues
MSIVMAVNTGSSSIRFALYRMDQGEIPLYTGALTSIASKDAMFSVIDSDGHALIREAVCVADHGAACEHVFGWLHDSNTL
RPDAVGHRIVHGGPLYSSPQVVSPALVESLHGLVVFAPQHLPQALQALDHASRLFPGSTQVACFDTAFHRSMPDVARLYA
LPEEVRRHGVQRYGFHGLSYQYLMSELERTVGTEIARGRLVLAHLGHGASMAAVKEGRSIDTTMGFSPAGGLVMSTRSGD
LDPGVLLFLLEQEHMDAAAITTMINSGSGMLGLSGISGDMQMLLDAVGDSHRARQAVDLFCYQAKKTIGAFAAAMGGLDS
VIFTGGIGEHSAVIRQRLCSGLGFLGIELDDGRNHHHEPVISGEASRVDIRVMATNEELMIARLVAAELSAHE
>Mature_392_residues
SIVMAVNTGSSSIRFALYRMDQGEIPLYTGALTSIASKDAMFSVIDSDGHALIREAVCVADHGAACEHVFGWLHDSNTLR
PDAVGHRIVHGGPLYSSPQVVSPALVESLHGLVVFAPQHLPQALQALDHASRLFPGSTQVACFDTAFHRSMPDVARLYAL
PEEVRRHGVQRYGFHGLSYQYLMSELERTVGTEIARGRLVLAHLGHGASMAAVKEGRSIDTTMGFSPAGGLVMSTRSGDL
DPGVLLFLLEQEHMDAAAITTMINSGSGMLGLSGISGDMQMLLDAVGDSHRARQAVDLFCYQAKKTIGAFAAAMGGLDSV
IFTGGIGEHSAVIRQRLCSGLGFLGIELDDGRNHHHEPVISGEASRVDIRVMATNEELMIARLVAAELSAHE

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=386, Percent_Identity=37.5647668393782, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1788633, Length=399, Percent_Identity=36.5914786967419, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 41993; Mature: 41861

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVMAVNTGSSSIRFALYRMDQGEIPLYTGALTSIASKDAMFSVIDSDGHALIREAVCV
CEEEEEEECCCCCEEEEEEECCCCCCCEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
ADHGAACEHVFGWLHDSNTLRPDAVGHRIVHGGPLYSSPQVVSPALVESLHGLVVFAPQH
CCCCCHHHHHHHHHCCCCCCCCHHHCCEEEECCCCCCCCCCCCHHHHHHHCCEEEECCHH
LPQALQALDHASRLFPGSTQVACFDTAFHRSMPDVARLYALPEEVRRHGVQRYGFHGLSY
HHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCHHHHHHHHCHHHHHHCCHHHHCCCCCCH
QYLMSELERTVGTEIARGRLVLAHLGHGASMAAVKEGRSIDTTMGFSPAGGLVMSTRSGD
HHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCEEEECCCCC
LDPGVLLFLLEQEHMDAAAITTMINSGSGMLGLSGISGDMQMLLDAVGDSHRARQAVDLF
CCCCEEEEEEEHHCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHH
CYQAKKTIGAFAAAMGGLDSVIFTGGIGEHSAVIRQRLCSGLGFLGIELDDGRNHHHEPV
HHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
ISGEASRVDIRVMATNEELMIARLVAAELSAHE
CCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIVMAVNTGSSSIRFALYRMDQGEIPLYTGALTSIASKDAMFSVIDSDGHALIREAVCV
EEEEEEECCCCCEEEEEEECCCCCCCEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
ADHGAACEHVFGWLHDSNTLRPDAVGHRIVHGGPLYSSPQVVSPALVESLHGLVVFAPQH
CCCCCHHHHHHHHHCCCCCCCCHHHCCEEEECCCCCCCCCCCCHHHHHHHCCEEEECCHH
LPQALQALDHASRLFPGSTQVACFDTAFHRSMPDVARLYALPEEVRRHGVQRYGFHGLSY
HHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCHHHHHHHHCHHHHHHCCHHHHCCCCCCH
QYLMSELERTVGTEIARGRLVLAHLGHGASMAAVKEGRSIDTTMGFSPAGGLVMSTRSGD
HHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCEEEECCCCC
LDPGVLLFLLEQEHMDAAAITTMINSGSGMLGLSGISGDMQMLLDAVGDSHRARQAVDLF
CCCCEEEEEEEHHCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHH
CYQAKKTIGAFAAAMGGLDSVIFTGGIGEHSAVIRQRLCSGLGFLGIELDDGRNHHHEPV
HHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
ISGEASRVDIRVMATNEELMIARLVAAELSAHE
CCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA